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Describe the role of phagocyte in non-specific
defence
Complete the stages involved in the
inflammatory response
Describe the role of cytokines
Damage to connective tissue causes,
__________ cells to release a chemical
called ___________
Unit 4 KA1:
Non-Specific Defence
Histamine causes ________________
of blood vessels and increased
permeability of __________________
List three examples first
line physical or chemical
defences
The increased blood flow and secretion
Describe the role of
NK cells
of _____________ leads to the
accumulation of ______cytes and
1.
the delivery of ______________
proteins and _____________ factors
2.
to the site of infection.
3.
Describe the role of phagocyte in
specific defence
Complete the stages involved in the clonal
selection of lymphocytes
Which type of
cell produces
antibodies?
___________ on a pathogen binds to
Describe the role of
antibodies
__________ on the lymphocyte
Unit 4 KA2:
Specific Defence
Lymphocyte then _______________
forming a clonal population
Lymphocytes become activated when…
Type of
lymphocyte
Allergy
Auto
immune
disease
List two ways in which
activated T Lymphocytes
respond to pathogens
Describe importance
of memory B
lymphocytes in the
secondary response
1.
Why are lymphocytes specific to one
antigen?
2.
.
Condition
Attacks
what type
of antigen
Describe the following patterns of
infectious disease spread
Sporadic
Define the
term antisepsis
Endemic
Unit 4 KA3: Transmission
and Control
Epidemic
Pandemic
List four ways in which
disease causing pathogens
can be transmitted
Define the term
quarantine
Describe two ways other than
quarantine that spread of pathogens
can be controlled
1.
1.
2.
2.
.
.
3.
4.
.
Describe the following terms relating to
clinical trials
Describe the contents of a
vaccine
Define the term
active
immunity
Placebo
What is an
adjuvant?
Unit 4 KA4: Vaccination
and Evasion
Randomised
The immunisation of large
percentages of the
population is known as…
Double Blind
Describe and give examples of three ways in which
pathogens evade the immune response
1. Antigenic Variation
.
Herd immunity protects non
immune individuals because…
2. Avoid Detection
.
.
3. Direct Attack on Immune System
.
Describe herd immunity threshold
and list some factors that influence it
.
Two reasons vaccination
programmes may be
unsuccessful