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Structural basis for quinine-dependent antibody binding to platelet integrin αIIbβ3 by Jianghai Zhu, Jieqing Zhu, Daniel W. Bougie, Richard H. Aster, and Timothy A. Springer Blood Volume 126(18):2138-2145 October 29, 2015 ©2015 by American Society of Hematology Alignment of 314.1 and 314.3 V domains and corresponding germline sequences. Jianghai Zhu et al. Blood 2015;126:2138-2145 ©2015 by American Society of Hematology Crystal structures of Fabs 314.1 and 314.3 and their complexes with quinine. Jianghai Zhu et al. Blood 2015;126:2138-2145 ©2015 by American Society of Hematology Details of quinine binding. Jianghai Zhu et al. Blood 2015;126:2138-2145 ©2015 by American Society of Hematology Quinine-Fab binding. Jianghai Zhu et al. Blood 2015;126:2138-2145 ©2015 by American Society of Hematology Models for DDAb binding to a cell-surface molecule. Jianghai Zhu et al. Blood 2015;126:2138-2145 ©2015 by American Society of Hematology