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April 11th, 2017 Group Innate Immunity and Viral Evasion Prof. Christine GOFFINET Post-doctoral position in virus-host communication: HIV-1, Chikungunya virus, HIV1/M.tb coinfection Post-doctoral position available in the Group Innate Immunity and Viral Evasion led by Prof. Christine Goffinet at TWINCORE, Hannover, Germany Research Topic: Our group is interested in the characterization of cellular restriction factors which inhibit viral infection and spread (Goffinet et al., Cell Host & Microbe 2009; Lodermeyer et al., Retrovirology 2013). Furthermore, we aim to elucidate cellular signaling pathways which sense virus infection and, vice versa, identify virus-mediated antagonistic strategies directed against those (Xu and Ducroux et al., Cell Host & Microbe 2016). Our pathogens of interests are HIV-1 and Chikungunya virus. Future projects furthermore aim to unravel innate immunity cross-talk in the context of bacterial-viral coinfections. http://www.twincore.de/en/institutes/experimental-virology/rg-innate-immunity-and-viralevasion/ Environment: TWINCORE, a joint venture of Helmholtz Center for Infection Research (HZI) and Hannover Medical School (MHH), aims at combining basic research and clinical application. It is a multi-disciplinary research institute and focuses on the study of microbial virulence factors, host-pathogens interactions and immunity to develop strategies for the diagnosis, prevention and therapy of human infectious diseases. http://www.twincore.de/en/home/ Qualifications: The successful candidate will have a strong and productive experience in virology, molecular biology, immunology and cell biology, and excellent technical, organization and communication skills. A strong interest in virology and innate immunity, the ability to perform creative and independent research, and a very high level of motivation is expected. Experience in working under BSL3 conditions and with primary cells is beneficial. Please send a cover letter describing past research accomplishments and future research interests, CV, and a list of 2-3 references to [email protected].