Download Genomics and Bioinformatics KEY CONCEPT Entire genomes are

Genomics and Bioinformatics
KEY CONCEPT
Entire genomes are sequenced, studied, and
compared.
Genomics and Bioinformatics
Gene sequencing: Determining the sequence of a gene
or an entire genome
• Determining the
sequence of a gene or
an entire genome
• The genomes of
several different
organisms have been
sequenced
Genomics and Bioinformatics
Genomics:
– Study of entire genomes
– can include the sequencing of the
genome
– Compare genomes within & across
species to find similarities &
differences among different
organisms
Genomics and Bioinformatics
Human Genome Project:
– Sequenced entire human
genome
– analyzed DNA from a few
people
– still working on identifying
all genes, finding their
locations & determining
their functions
Genomics and Bioinformatics
Bioinformatics:
• Using computer databases to organize & analyze the vast
amounts of data that result from studies of genetics (and other
biological information)
Genomics and Bioinformatics
DNA microarrays:
• Allow scientists to study
the expression of many
genes at one time
• Used to compare gene
expression in different
types of cells
Genomics and Bioinformatics
Proteomics: the study & comparison of proteins within
& across species
• Study & comparison of proteins within & across species
• Used to study evolutionary relationships & human diseases
Genomics and Bioinformatics
Summary of these techniques:
• Bioinformatics is the use of computer databases to
organize and analyze biological data.
• DNA microarrays are used to study the expression of
many genes at once.
• Proteomics is the study and comparison of proteins