TRANSLOCATIONS INVOLVING T H E THIRD AND THE FOURTH
... Cytological changes produced by the translocations.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Genetical consequences of the breakage of the third chromosome in the translocations.. .. Non-disjunction of the fourth chromosome in the translocations.. ..................... Behavi ...
... Cytological changes produced by the translocations.. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . Genetical consequences of the breakage of the third chromosome in the translocations.. .. Non-disjunction of the fourth chromosome in the translocations.. ..................... Behavi ...
Complete genome sequence of the prototype lactic acid bacterium
... of the resulting products, was used to close the remaining 800 gaps, in combination with inverse PCR for the gaps for which no linkage information could be obtained. To verify the complete assembly, PCRs predicted to be separated by 9 kb were performed on the genome, covering the entire genome with ...
... of the resulting products, was used to close the remaining 800 gaps, in combination with inverse PCR for the gaps for which no linkage information could be obtained. To verify the complete assembly, PCRs predicted to be separated by 9 kb were performed on the genome, covering the entire genome with ...
Polyploidy
... – the population of haploid organisms is then screened for favorable traits, – the plants are then treated with colchicine which generates a 2n plant homozygous for the ...
... – the population of haploid organisms is then screened for favorable traits, – the plants are then treated with colchicine which generates a 2n plant homozygous for the ...
pdf
... hypothetical proteins. A transposase (Noc_A0021), phage integrase (Noc_A0015), and a small number of other phagerelated genes along with restriction modification systems are also found on this replicon. A possible replication protein (Noc_A0039) whose only putative homologue (56% similar over 80% of ...
... hypothetical proteins. A transposase (Noc_A0021), phage integrase (Noc_A0015), and a small number of other phagerelated genes along with restriction modification systems are also found on this replicon. A possible replication protein (Noc_A0039) whose only putative homologue (56% similar over 80% of ...
Standard PDF - Wiley Online Library
... consider in reference to speculations about the possible relationship between the gene content and the life style of P. carinii. A stark feature of P. carinii is its failure to multiply in vitro, which implies that the microbe lacks certain biosynthetic capabilities, and is therefore dependent on a ...
... consider in reference to speculations about the possible relationship between the gene content and the life style of P. carinii. A stark feature of P. carinii is its failure to multiply in vitro, which implies that the microbe lacks certain biosynthetic capabilities, and is therefore dependent on a ...
Chromosome Variation
... Because developmental processes often require the interaction of many proteins, they may critically depend on the relative amounts of the proteins. If the amount of one protein increases while the amounts of others remain constant, problems can result ( ◗ FIGURE 9.9). Although duplications can have ...
... Because developmental processes often require the interaction of many proteins, they may critically depend on the relative amounts of the proteins. If the amount of one protein increases while the amounts of others remain constant, problems can result ( ◗ FIGURE 9.9). Although duplications can have ...
Spinocerebellar ataxia type 1 (SCA1): Phenotype-genotype
... Sequence analysis revealed that the 14 normal SCA1 alleles with 29 and 30 triplets as well as the alleles with 35 ± 38 triplets are interrupted by the sequence CAT CAG CAT. In alleles with 39 ± 41 triplets the interruption is missing in six of seven cases. DNA sequences are summarised in Table 1. Al ...
... Sequence analysis revealed that the 14 normal SCA1 alleles with 29 and 30 triplets as well as the alleles with 35 ± 38 triplets are interrupted by the sequence CAT CAG CAT. In alleles with 39 ± 41 triplets the interruption is missing in six of seven cases. DNA sequences are summarised in Table 1. Al ...
Product description P018-G1 SHOX-v03 - MRC
... SHOX gene function. - Please note that single exon deletions have a considerable chance of being a false positive result, either due to non-pathogenic copy number variants (Benito-Sanz et al. 2011a), mutations within the probe binding site (Barca-Tierno et al. 2011) or due to impurities in the DNA. ...
... SHOX gene function. - Please note that single exon deletions have a considerable chance of being a false positive result, either due to non-pathogenic copy number variants (Benito-Sanz et al. 2011a), mutations within the probe binding site (Barca-Tierno et al. 2011) or due to impurities in the DNA. ...
Methods Five 1536-SNP GoldenGate assays (Fig. 1) Three pilot
... University Genomics Institute) and Alan Schulman (University of Helsinki). For pairwise genotype comparisons, a SNP was accepted only if there were at least two sequences from each genotype and no disagreement at the SNP position between opposite strands from a single clone. A base call was used onl ...
... University Genomics Institute) and Alan Schulman (University of Helsinki). For pairwise genotype comparisons, a SNP was accepted only if there were at least two sequences from each genotype and no disagreement at the SNP position between opposite strands from a single clone. A base call was used onl ...
Genetic Analysis of Variation in Human Meiotic Recombination
... analysis, we used the genotype data from members of twogeneration families that have two or more children to infer recombination phenotypes of the parents in these families. The 511 AGRE families have an average of 2.26 children (median = 2; range: 2 to 7) and provided data for 1,155 female and 1,15 ...
... analysis, we used the genotype data from members of twogeneration families that have two or more children to infer recombination phenotypes of the parents in these families. The 511 AGRE families have an average of 2.26 children (median = 2; range: 2 to 7) and provided data for 1,155 female and 1,15 ...
Array-based sequencing of filaggrin gene for
... The filaggrin gene (FLG) is essential for skin differentiation and epidermal barrier formation with links to skin diseases, however it has a highly repetitive nucleotide sequence containing very limited stretches of unique nucleotides for precise mapping to reference genomes. Sequencing strategies u ...
... The filaggrin gene (FLG) is essential for skin differentiation and epidermal barrier formation with links to skin diseases, however it has a highly repetitive nucleotide sequence containing very limited stretches of unique nucleotides for precise mapping to reference genomes. Sequencing strategies u ...
Persistence and Loss of Meiotic Recombination
... individuals one at a time to undergo meiosis until N euploid gametes have been obtained. Highly fit individuals may contribute more than one meiosis while less fit individuals may contribute none. Meiosis: The molecular events of meiosis are explicitly specified in the model: DNA replication, DNA br ...
... individuals one at a time to undergo meiosis until N euploid gametes have been obtained. Highly fit individuals may contribute more than one meiosis while less fit individuals may contribute none. Meiosis: The molecular events of meiosis are explicitly specified in the model: DNA replication, DNA br ...
Evolutionary dynamics of nematode operons
... model postulates that coregulation of functionally related genes by a single promoter (as in operons) is beneficial. Indeed, prokaryotic operons often consist of genes involved in the same metabolic pathways that need to be coregulated (Lawrence 2002). But in C. elegans, constituent genes of an oper ...
... model postulates that coregulation of functionally related genes by a single promoter (as in operons) is beneficial. Indeed, prokaryotic operons often consist of genes involved in the same metabolic pathways that need to be coregulated (Lawrence 2002). But in C. elegans, constituent genes of an oper ...
gsea user guide
... dataset. This prevents flat genes from driving the clustering result and improves processing time by focusing on a smaller number of interesting genes. The GSEA algorithm does not filter the expression dataset and does not benefit from your filtering of the expression dataset. During the analysis, g ...
... dataset. This prevents flat genes from driving the clustering result and improves processing time by focusing on a smaller number of interesting genes. The GSEA algorithm does not filter the expression dataset and does not benefit from your filtering of the expression dataset. During the analysis, g ...
NCBI Molecular Biology Resources
... • Examples: Refseq, TPA, RefSNP, UniGene, Protein, Structure, ...
... • Examples: Refseq, TPA, RefSNP, UniGene, Protein, Structure, ...
Chapter 1: What is PKU?
... one PKU gene and one normal gene) • 25% chance of inheriting two normal genes There is a 25 percent chance that another child born to the same parents will also have PKU. Individuals with PKU can have children that do not have PKU if their partner is unaffected. However, their children will be carri ...
... one PKU gene and one normal gene) • 25% chance of inheriting two normal genes There is a 25 percent chance that another child born to the same parents will also have PKU. Individuals with PKU can have children that do not have PKU if their partner is unaffected. However, their children will be carri ...
Introns Structure Patterns of Variation in Nucleotide Composition in
... regions. In addition, negative correlations among codon positions inside internal coding regions suggest stabilizing selection for a GC-content level that was similar in both species. Finally, the intron/exon architecture was shown to affect all codon positions and reveals a pervasive impact of gene ...
... regions. In addition, negative correlations among codon positions inside internal coding regions suggest stabilizing selection for a GC-content level that was similar in both species. Finally, the intron/exon architecture was shown to affect all codon positions and reveals a pervasive impact of gene ...
Tracing the Thread of Plastid Diversity through the Tapestry of Life
... Herrmann 1998). Those plastid proteins not encoded in the plastid genome are encoded in the nuclear genome and must be targeted to the plastid. Three mechanisms underlie this reduction of the plastid genome; gene loss, substitution, and transfer. First, in the case of gene loss, genes that no longer ...
... Herrmann 1998). Those plastid proteins not encoded in the plastid genome are encoded in the nuclear genome and must be targeted to the plastid. Three mechanisms underlie this reduction of the plastid genome; gene loss, substitution, and transfer. First, in the case of gene loss, genes that no longer ...
Additional Table 1. Genotype and phenotype of the
... kb, 14,823,878-15,041,954, genomic yes build hg 18). One gene involved (MACROD2 ). No parental studies were performed. The clinical significance of these copy number variants is unclear. ...
... kb, 14,823,878-15,041,954, genomic yes build hg 18). One gene involved (MACROD2 ). No parental studies were performed. The clinical significance of these copy number variants is unclear. ...
Phylogenetic analysis of three complete gap
... from the zebrafish genome, some are found as single relatives, and others are found in multiple copies. In addition, the zebrafish has 14 apparently novel connexins, several of which arose by recent tandem duplication events. This analysis provides evidence that the connexin gene family is increasin ...
... from the zebrafish genome, some are found as single relatives, and others are found in multiple copies. In addition, the zebrafish has 14 apparently novel connexins, several of which arose by recent tandem duplication events. This analysis provides evidence that the connexin gene family is increasin ...
The amelogenin gene
... protein is now well characterized from the data of amino acid sequences which have been shown to be at a high degree of homology between all species investigated to date. The gene structure of this protein has been demonstrated and it is confirmed that there are two amelogenin genes, one on the X.ch ...
... protein is now well characterized from the data of amino acid sequences which have been shown to be at a high degree of homology between all species investigated to date. The gene structure of this protein has been demonstrated and it is confirmed that there are two amelogenin genes, one on the X.ch ...
Intellectual property rights and innovation: Evidence from
... From this empirical context, I construct three research designs to test for the effects of Celera’s IP on subsequent scientific research and product development outcomes. The first research design tests whether genes that ever had Celera’s IP differ in subsequent innovation, as of 2009, from genes ...
... From this empirical context, I construct three research designs to test for the effects of Celera’s IP on subsequent scientific research and product development outcomes. The first research design tests whether genes that ever had Celera’s IP differ in subsequent innovation, as of 2009, from genes ...
The first page should show the paper title, names and addresses of
... Galliformes could be resolved using the FISH on lampbrush chromosomes as an investigative procedure? On the other hand, why should we still use time-consuming methods like comparative FISH mapping on LBCs when next-generation sequencing approaches are opening up new opportunities for genome-wide ana ...
... Galliformes could be resolved using the FISH on lampbrush chromosomes as an investigative procedure? On the other hand, why should we still use time-consuming methods like comparative FISH mapping on LBCs when next-generation sequencing approaches are opening up new opportunities for genome-wide ana ...
Copy-number variation
Copy-number variations (CNVs)—a form of structural variation—are alterations of the DNA of a genome that results in the cell having an abnormal or, for certain genes, a normal variation in the number of copies of one or more sections of the DNA. CNVs correspond to relatively large regions of the genome that have been deleted (fewer than the normal number) or duplicated (more than the normal number) on certain chromosomes. For example, the chromosome that normally has sections in order as A-B-C-D might instead have sections A-B-C-C-D (a duplication of ""C"") or A-B-D (a deletion of ""C"").This variation accounts for roughly 13% of human genomic DNA and each variation may range from about one kilobase (1,000 nucleotide bases) to several megabases in size. CNVs contrast with single-nucleotide polymorphisms (SNPs), which affect only one single nucleotide base.