Download Correction: The paper by Yamamoto et al. (1998) that appeared in

Correction: The paper by Yamamoto et al. (1998) that appeared in the March 15, 1998 issue
failed to cite an earlier paper that reached similar conclusions. In particular, Kim et al. (1997)
also analyzed knock-out mice lacking the protein repair enzyme L-isoaspartate
methyltransferase and demonstrated the accumulation of altered proteins in several tissues,
including brain, leading to the retardation of growth and fatal seizures. The authors were
unaware of this work at the time of submitting their manuscript. They also apologize for the
direct use of sentences from the introduction of a previous paper (Lowenson ard Clarke,
1992) without appropriate citation.
Kim E, Lowenson JD, MacLaren DC, Clarke S, Young SG (1997) Deficiency of a proteinrepair enzyme results in the accumulation of altered proteins, retardation of growth, ard fatal
seizures in mice. Proc Natl Acad Sci USA 94:6132-6137.
Lowenson JD, Clarke S (1992) Recognition of D-aspartyl residues in polypeptides by the
erythrocyte L-isoaspartyl/D-aspartyl protein methyltransferase. J Biol Chem 267:5985-5995.
Yamamoto A, Takagi H. Kitamura Dn Tatsuoka H. Nakano H. Kawano H. Kuroyanagi H.
Yahagi Y, Kobayashi S, Koizumi K, Sakai T, Saito K, Chiba T, Kawamura K, Suzuki K,
Watanabe T, Mori H, Shirasawa T (1998) Deficiency in protein L-isoaspartyl
methyltransferase results in a fatal progressive epilepsy. J Neurosci 18:2063-2074.