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Table 1. Proteins encoded by representative ESTs cloned from Crepidula fornicata
Parentheses include specific family members recovered (see www.life.illinois.edu/henry for further details)
Transcriptional Regulation
Beta-catenin
Bicoid type transcription factor Pitx
Bone morphogenetic protein 2 precursor
Brachyenteron
Brachyury
Cnot, partial
Ddx5 protein
DNA-dependent protein kinase catalytic subunit
DNA polymerase III subunits (gamma, tau)
DNA topoisomerase I
Decapentaplegic
Eyes absent 1
Floating head
Forkhead box M1-like
transcription factor
Goosecoid
H3 histone, family 3A
Heterogenous nuclear ribonucleoprotein L
Lark
Leucine-rich repeat protein (LRRP)
LIM-domain protein
Maturase
Notocord homeobox-like protein
Nucleolin
NusB-family protein
ORF2-encoded protein
Pax-B
Pitx
Pl10
Polymerase RNA III-DNA directed polypeptide D
Probable RNA-dependent helicase p72
Reverse transcriptase
Reverse transcriptase-like protein
rRNA promoter binding protein
Seali
Similar to engrailed
SWI/SNF complex subunit SMARCC2
Superkiller viralicidic activity 2-like 2
Transcription elongation factor SPT6
Transcriptional activator FtrA
Twist
Vasa
Zinc finger proteins (7, 181, 233, 271)
Matrix metalloproteinases
Zinc metalloproteinase, STE24 homolog
Cell Cycle Proteins
CDC5 cell division cycle 5-like
CDH1-D
Cell division cycle and apoptosis regulator 1
CHK1 checkpoint homolog
EGF-like domain-containing protein
Programmed cell death (4a, 11)
Structural Proteins
Alpha tubulin a1
Actin binding protein anillin
Myosin 31DF
Similar to CaLPain family member (clp-2),
T-complex protein 1 subunit delta
Striatin, calmodulin binding protein 3
Cell Signaling Proteins
Alpha-L1 nicotinic acetyl choline receptor
Allatotropin neuropeptide precursor
Ankyrin (2, 3, UNC-44)
Ankyrin repeat domain protein 17
BMP receptor I (ALK3)
Cell Signaling Proteins (cont.)
Calmodulin
Doublecortin domain-containing 5
G protein-coupled receptor, putative
Heat shock cognate 70 isoform 1
Mitogen-activated protein kinase kinase kinase 1
Na+/K+ ATPase alpha subunit
Nodal
Protein phosphatase 4, catalytic subunit
Smad (1/5, 2/3, 4)
Smurf (1, 2)
TGF RECEPTOR I (ALK5)
Tnf receptor-associated factor 7
WD domain, G-beta repeat
WD-repeat protein, putative
Metabolic Proteins
6-phosphofructo-2-kinase/fructose-2,6biphosphatase bifunctional
ATP Synthase FO, subunit 6
ATPase, class I, type 8B, member 2
ATP-binding cassette, sub-family C, member 3
isoform MRP3
Cytochrome b
Cytochrome c oxidase subunit IV
Cytochrome oxidase subunits (I , II)
Cytochrome P450
Cytocrome P450-like protein precursor
Cytochrome P450-like TBP protein
Isocitrate dehydrogenase, mitochondrial precursor
Left-right dynein
NADH hydrogenase 1, subunits (2, 4, 5)
Nucleoside diphosphate kinase
Outer mitochondrial translocase subunit
Ubiquinol-cytochrome c reductase core protein II
isoform 1
Ubiquitin conjugating enzymes (E2, J2)
Ubiquitin-activating enzyme E1
Protein Processing & Degradation
60s ribosomal proteins (L7a, L34, L35a)
39S ribosomal protein (L13)
Cathepsin I
Cathepsin L precursor
Chaperonin containing TCP1, subunit 2
Elongation factor 1 (alpha, beta)
Kelch-like 29
Ribosomal proteins (L4, S10, S20)
rRNA intron-encoded homing endonuclease
Thioester-containing protein
Threonyl-tRNA synthetase
Translationally-controlled tumor protein
Transport Proteins
Scavenger receptor cysteine-rich protein variant 1
Sec23 protein
Solute carrier family 6 (neurotransmitter
transporter, glycine), member 5
Stress/Inflammatory/Innate Immunity
Defender against cell death 1
Miscellaneous Proteins
Cell wall protein FLO11p, putative
Chromosome 10 open reading frame 46
Dynamin-associated protein
Hypothetical proteins (40 total)
Senescence-associated protein
Unknown proteins (64 total)