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NURS 315/501 Bootcamp Lecture: Disorders of cardiac function Perfusion of the Heart Describe how is the myocardium supplied with oxygen. Discuss the factors that regulate blood flow to the myocardium. Volume, pressure, resistance, and flow Cardiac Conduction System Describe the cardiac conduction system. SA node, AV node, Bundle of His, bundle branches, Purkinje fibers Coronary Perfusion and Electrical Activity Describe the 3 phases of the action potential. Resting membrane potential Depolarization Repolarization Correlate the ECG events with the mechanical events of a cardiac cycle. Phases of the Action Potential Describe the 5 phases of a cardiac action potential. Phase Phase Phase Phase Phase 4 0 1 2 3 Coronary Heart Disease Describe the pathogenesis of CAD. Discuss how does atherosclerosis in coronary arteries can lead to ischemia, injury, and infarction. Compare and contrast ischemia, injury, and infarction. Describe the pathologic changes associated with MI. Coronary Heart Disease Schematically represent the 2 types of coronary heart disease. Coronary Heart Disease Acute Coronary Syndrome: Define unstable angina Describe changes in ECG and serum markers during a NSTEMI vs. STEMI. What does abnormal Q-waves in a 12-lead ECG mean? Coronary Heart Disease Chronic Ischemic Disease. Compare and contrast stable angina, variant/vasospastic angina, and silent myocardial infarction. Coronary Heart Disease Identify the goals for the management of angina, CHD, and AMI. Describe the management strategies utilized to achieve management goals. Anti-anginal drugs Anti-platelet therapy Anticoagulant therapy Heart Failure Describe the common causes of heart failure. Describe the cycle through which compensatory mechanisms lead to heart failure and how is the cycle perpetuated. Describe the compensatory mechanisms involved in the physiologic response to decreased cardiac output. Heart Failure Distinguish between systolic and diastolic heart failure. Distinguish between right and left sided heart failure. Identify the goals of HF management. Heart Failure Describe the role of diuretics in the management of HF Describe how ACE-I and ARB’s achieve the goals for HF management. Describe the function of beta-blockers in the management of HF. Describe the function of digoxin in the management of HF. What role does calcium channel blockers play in the management of HF? Disorders of Valve Function Compare and contrast the following disorders of valve function: Mitral stenosis Mitral regurgitation Aortic stenosis Aortic regurgitation Disorders of cardiac electrical conduction Compare and contrast the following sinus dysrhythmias; Normal sinus rhythm Sinus bradycardia Sinus tachycardia Sinus dysrhythmia Compare and contrast the following atrial dysrhythmias: Premature atrial contraction Atrial flutter Atrial fibrillation Disorders of cardiac electrical conduction Compare and contrast the following ventricular dysrhythmias: Premature ventricular contraction Ventricular tachycardia Ventricular fibrillation Compare and contrast the following atrioventricular conduction dysrhythmias: 1st degree AV block 2nd degree AV block 3rd degree AV block Disorders of cardiac electrical conduction Outline in a table: The four classes of anti-dysrhythmic drugs, Agents classified under the class, Their mechanism of action, Indications, Adverse effects, Special considerations. Shock Define shock Name an important serum marker used to assess cellular aerobic metabolism in tissues. Identify SNS compensatory mechanisms to ensure adequate tissue oxygenation. Shock Compare and contrast the 4 types of circulatory shock. Name common complications of shock on organ systems. Shock What is the ultimate goal of therapy in management of shock? Identify mechanisms to ensure adequate oxygen delivery during shock.