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RESEARCH PAPERS Proteins Endogenous cleavage of the Arg-379-Ala-380 bond in vitronectin results in a distinct conformational change which 'buries' Ser-378, its site of phosphorylation by protein kinase A Effects of lithium ions on actin polymerization in the presence of magnesium ions The interaction of troponin C with phosphofructokinase. Comparison with calmodulin Structure and biological activities of a new mastoparan isolated from the venom of the hornet Vespa basalis Further studies on the topography of the N-terminal region of human platelet glycoprotein Illa. Localization of monoclonal antibody epitopes and the putative fibrinogen-binding sites Comparative properties of three functionally different but structurally related serpin variants from horse plasma The principal site of glycation of human complement Factor B The secondary structure of Protein G', a robust molecule Biosynthesis of bone proteins [SPP-1 (secreted phosphoprotein-1, osteopontin), BSP (bone sialoprotein) and SPARC (osteonectin)] in association with mineralized-tissue formation by fetal-rat calvarial cells in culture Carbohydrate-recognition domains as tools for rapid purification of recombinant eukaryotic proteins Enzymes Radioimmunoassay of carbonic anhydrase VI in saliva and sheep tissues The binding of D-gluconohydroximo-1,5-lactone to glycogen phosphorylase. Kinetic, ultracentrifugation and crystallographic studies A comparison of the active site of maltase-glucoamylase from the brush border of rabbit small intestine and kidney by chemical modification studies Purification and properties of adenosine 5'-phosphosulphate sulphotransferase from Euglena Hepatic protein tyrosine phosphatases in the rat Purification and characterization of acidic glutathione S-transferase 6 from human brain Theta, a new class of glutathione transferases purified from rat and man Characterization of the enzyme activity of human plasma lipoprotein (a) using synthetic peptide substrates Fitting integrated enzyme rate equations to progress curves with the use of a weighting matrix Effects of directed mutagenesis on conserved arginine residues in a human Class Alpha glutathione transferase 2,3-Di-O-tetradecyl- l-O-(,/-D-glucopyranosyl)-sn-glycerol is a substrate for human glucocerebrosidase Carbohydrates and lipids Purification and N-terminal amino acid sequence of a chondroitin sulphate/dermatan sulphate proteoglycan isolated from intima/ media preparations of human aorta (vii) D. CHAIN, B. KORC-GRODZICKI, T. KREIZMAN & S. SHALTIEL 387-394 R. COLOMBO, A. MILZANI, P. CONTINI & I. DALLE DONNE J. LAN & R. F. STEINER 421-425 C.-L. Ho & L.-L. HWANG 453-456 J. J. CALVETE, J. ARIAS, M. V. ALVAREZ, M. M. LOPEZ, A. HENSCHEN & J. GONZALEZ-RODRIGUEZ J. POTEMPA, J. K. WUNDERLICH & J. TRAVIS M. A. NIEMANN, A. S. BHOWN & E. J. MILLER C. R. GOWARD, L. I. IRONS, J. P. MURPHY & T. ATKINSON T. NAGATA, C. G. BELLOWS, S. KASUGAI, W. T. BUTLER & J. SODEK 457-463 445-451 465-471 473-480 503-507 513-520 M. E. TAYLOR & K. DRICKAMER 575-580 R. T. FERNLEY, R. D. WRIGHT & J. P. COGHLAN A. C. PAPAGEORGIOU, N. G. OIKONOMAKOS, D. D. LEONIDAS, B. BERNET, D. BEER & A. VASELLA B. PEREIRA & S. SIVAKAMI 313-316 J. LI & J. A. SCHIFF 355-360 P. A. GRUPPUSO, J. M. BOYLAN, B. L. SMILEY, R. J. FALLON & D. L. BRAUTIGAN T. SUZUKI, D. C. SHAW & P. G. BOARD 361-367 D. J. MEYER, B. COLES, S. E. PEMBLE, K. S. GILMORE, G. M. FRASER & B. KETTERER M. JAUHIAINEN, J. METSO, P. KOSKINEN & C. EHNHOLM R. FRANCO, J. M. ARAN & E. I. CANELA 409-414 G. STENBERG, P. G. BOARD, I. CARLBERG & B. MANNERVIK R. H. GLEW, V. GOPALAN, C. A. HUBBELL, R. V. DEVRAJ, R. A. LAWSON, W. F. DIVEN & D. A. MANNOCK 549-555 G. ST6CKER, H. E. MEYER, C. WAGENER & H. GREILING 415-420 329-338 349-354 405-408 491-496 509-511 557-563 CONTENTS (continued) Ganglioside incorporation and release by the isolated perfused rat liver Gene structure and expression Characterization and organization of the genes encoding the A-, Band C-chains of human complement subcomponent Clq. The complete derived amino acid sequence of human Clq The translation in vitro of rat ornithine decarboxylase mRNA is blocked by its 5' untranslated region in a polyamine-independent way Structure of human glutathione S-transferase class Mu genes c-myc mRNA in cytoskeletal-bound polysomes in fibroblasts Regulation of metabolism Transport in isolated rat hepatocytes of the phospho-oligosaccharide that mimics insulin action. Effects of adrenalectomy and glucocorticoid treatment Metabolic consequences of methylenecyclopropylglycine poisoning in rats Counter-regulation by insulin and isoprenaline of a prominent fatassociated phosphoprotein doublet in rat adipocytes Antitrypanosomal effects of polyamine biosynthesis inhibitors correlate with increases in Trypanosoma brucei brucei S-adenosyl-Lmethionine Modulation of the activity of acetyl-CoA carboxylase and other lipogenic enzymes by growth hormone, insulin and dexamethasone in sheep adipose tissue and relationship to adaptations to lactation Glucose metabolic pathways in the anaerobic rumen fungus Neocallimastix frontalis EB1 88 Relative rates of biosynthesis of collagen type I, type V and type VI in calf cornea Membranes and bioenergetics An acetylation method for the quantification of membrane lipids, including phospholipids, polyphosphoinositides and cholesterol Ectocytosis caused by sublytic autologous complement attack on human neutrophils. The sorting of endogenous plasma-membrane proteins and lipids into shed vesicles Correlation between Ca2+ uptake, Ca2+ efflux and phosphoenzyme level in sarcoplasmic-reticulum vesicles Maintenance of structural and functional characteristics of skeletalmuscle mitochondria and sarcoplasmic-reticular membranes after chronic ethanol treatment Further evidence that cyclosporin A protects mitochondria from calcium overload by inhibiting a matrix peptidyl-prolyl cis-trans isomerase. Implications for the immunosuppressive and toxic effects of cyclosporin Receptors and signal transduction Okadaic acid identifies a phosphorylation/dephosphorylation cycle controlling the inhibitory guanine-nucleotide-binding regulatory protein G12 Cell density modulates the decrease of cytosolic free Ca2+ induced by atrial natriuretic hormone, S-nitroso-N-acetylpenicillamine and 8-bromo cyclic GMP in cultured rat mesangial cells A pertussis-toxin-sensitive protein controls exocytosis in chromaffin cells at a step distal to the generation of second messengers Nucleoside triphosphates promote the transformation of Ah receptor to its DNA-binding form Ontogeny of guanine-nucleotide-binding regulatory proteins in rabbit liver (viii) S. C. KIVATINITZ, A. MIGLIO & R. GHIDoNI 581-585 G. C. SELLAR, D. J. BLAKE & K. B. M. REID 481-490 H. VAN STEEG, C. T. M. VAN OOSTROM, H. M. HODEMAEKERS, L. PETERS & A. A. M. THOMAS J. B. TAYLOR, J. OLIVER, R. SHERRINGTON & S. E. PEMBLE J. E. HESKETH, G. P. CAMPBELL & P. F. WHITELAW 521-526 J. F. ALVAREZ, J. A. SANcHEz-ARIAS, A. GUADANO, F. ESTEVEZ, I. VARELA, J. E. FELIU & J. M. MATO K. MELDE, S. JACKSON, K. BARTLETT, H. S. A. SHERRATT & S. GHISLA R. A. MooNEY & K. L. BORDWELL 369-374 587-593 607-609 395-400 433-438 T. L. BYERS, T. L. BUSH, P. P. MCCANN & A. J. BITONTI 527-533 R. G. VERNON, M. C. BARBER & E. FINLEY 543-548 J. V. O'FALLON, R. W. WRIGHT, JR. & R. E. CALZA P. KERN, M. MENASCHE & L. ROBERT 595-599 615-617 J. M. STEIN, G. SMITH & J. P. LuzIo 375-379 J. M. STEIN & J. P. LuzIo 381-386 J. C. BENECH, A. GALINA & L. DE MEIS 427-432 F. CARDELLACH, T. F. TARASCHI, J. S. ELLINGSON, C. D. STUBBS, E. RUBIN & J. B. HOEK E. J. GRIFFITHS & A. P. HALESTRAP 565-573 611-614 M. BUSHFIELD, B. E. LAVAN & M. D. HOUSLAY 317-321 F. LERMIOGLU, J. GOYAL & A. HASSID 323-328 J.-M. SONTAG, D. THIERSE, B. RoUOT, D. AUNIS & M.-F. BADER A. J. CARY & J. J. DOUGHERTY 339-347 Y. KAWAI & I. J. ARINZE 439444 401404 CONTENTS (continued) Interaction of human platelets with laminin and identification of the 67 kDa laminin receptor on platelets Cell biology and development Investigation of the role of calpain as a stimulus-response mediator in human platelets using new synthetic inhibitors Ferritin accumulation and degradation in different organs of pea (Pisum sativum) during development BJ LETTERS Structural distinction of rat GSH transferase subunit 10 On the mechanism of induction of chick embryo hepatic &aminolaevulinate synthase by translational blockers Does MAPIB bind to tubulin through the interaction of a-helices? Inositol 1,4,5-trisphosphate 3-kinase activity in high-speed supernatants from rat pancreatoma cells, AR4-2J (ix) N. N. TANDON, E. A. HOLLAND, U. KRALISZ, H. K. KLEINMAN, F. A. ROBEY & G. A. JAMIESON 535-542 J. ANAGLI, J. HAGMANN & E. SHAw 497-502 S. LOBREAUX & J.-F. BRIAT 601-606 D. J. MEYER, K. S. GILMORE, B. COLES, 619 K. DALTON, P. B. HULBERT & B. KETTERER G. RYAN & I. Z. ADES 619-621 J. AVILA F. S. MENNITI & J. W. PUTNEY, JR. 621-622 622-623