Download MIP636- Mechanisms of Viral Infection and Disease

MIP636- Mechanisms of Viral Infection and Disease
Instructor Information:
Dr. Ken Olson
Office Location: AIDL Foothills Campus
Phone: 491-8604
E-mail: [email protected]
Office Hours: by appointment
Dr. Sandra L. Quackenbush
Office Location: 315 Pathology Bldg
Phone: 491-3545
E-mail: [email protected]
Office Hours: by appointment
Required Texts:
None required. Electronic copies of course-related materials, such as peer-reviewed
publications will be posted on RamCT.
Course Description:
This graduate course will focus on the mechanisms by which viruses cause disease.
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Course Objectives or
Course Learning
Outcomes:
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Course Prerequisite
Credit Hours
Class Breakdown
Teaching Strategies
Course Policies and
Procedures:
Students will be able to describe viral evolution
Students will be able to describe how viruses are transmitted and spread within the
host and populations
Students will be able to explain the mechanisms by which the host elicits an
immune response
Students will be able to describe the mechanisms by which viruses modulate the
immune response
Students will be able to describe the mechanisms by which viruses cause tissue
damage and loss of function, inflammation and cancer
MIP420 or MIP530
4
Lecture Hours: 3
Recitation: 1
Total hours: 4
Teaching strategies for this course will be lecture, presentation of current literature and class
discussions
The course is designed to require two hours minimum outside work for each contact hours
in achieving the learning objectives through the readings and presentation assignments.
Attendance: Class attendance strongly advised.
Academic Honesty:
This course will adhere to the CSU Academic Integrity Policy as found in the
General Catalog - 1.6, pages 7-9. (http://www.catalog.colostate.edu/Content/files/2012/
FrontPDF/1.6POLICIES.pdf) and the Student Conduct Code
(http://www.conflictresolution.colostate.edu/conduct-code ). At a minimum, violations
will result in a grading penalty in this course and a report to the Office of Conflict
Resolution and Student Conduct Services.
Late work & Educational Responsibility: All assignments for the week must be
completed by the last day in the week unless an alternate due date has been previously
approved or documentation has been provided for extreme circumstances. It is the
student's responsibility to communicate with the instructor about extreme circumstances or
questions concerning the assignment and their due dates.
Grading Scale: Students will be evaluated and assessed using in class exam, oral
presentation and written critique of an assigned paper and participation in discussions. This
class uses a traditional A-F grading system.
A- 91-100%
B- 81-90%
C- 71-80%
D- 61-70%
F- less than 61%
Evaluation
Breakdown:
Midterm Examination
Final Examination
Paper presentation and
critique
Discussions
Total:
30 points
35 points
25 points
10 points
100 points
MIP636- Mechanisms of Viral Infection and Disease
Spring 2015
Wednesday and Friday 2:00- 4:30 pm
Pathology Room 109
Lecturer
1) Jan 21, 2015 (W) Introduction to course
Olson
Overview of viral structure and replication
Wilusz
mailto:[email protected]
2) Jan 23, 2015 (F)
Origin and emergence of viral diseases
Olson
3) Jan 28, 2015 (W) Bioinformatics: tools for understanding
virus-host interactions
mailto:[email protected]
Stenglein
4) Jan 30, 2015 (F)
Viral Epidemiology: an overview
Moore
5) Feb 4, 2015 (W)
Viral variation and evolution in viral pathogenesis Ebel
mailto:[email protected]
6) Feb 6, 2015 (F)
Life of viruses in cells: entry/exit
mailto:[email protected]
Perera
7) Feb 11, 2015 (W) Mechanisms of adaptive immunity
and evasion by viruses
mailto:[email protected]
Schenkel
8) Feb 13, 2015 (F) Mechanisms of innate immunity and evasion
by viruses
mailto:[email protected]
Blair
9) Feb 18, 2015 (W) Vaccines and innate immunity
mailto:[email protected]
Dean
10) Feb 20, 2015 (F) Virus-induced apoptosis
mailto:[email protected]
Clarke
11) Feb 25, 2015 (W) Overview of pathology
Experimental approaches to viral pathogenesis\
mailto:[email protected]
Aboellail
12) Feb 27, 2015 (F) Virus-induced immunopathology
Aboellail
13) Mar 4, 2015 (F) Virus induced immunosuppression;
pathogenesis of AIDS
Akkina
[email protected]
14) Mar 6, 2015 (W) Host factors in disease
mailto:[email protected]
Schountz
15) Mar 11, 2015 (W) Viral oncogenesis- RNA viruses
and DNA viruses
Quackenbush
16) Mar 13, 2015 (F) Midterm exam
17) March 14-23 2015 Spring Break
18) Mar 25, 2015 (W) Viral encephalitis
mailto:[email protected]
Bowen
19) Mar 27, 2015 (F) Alphaherpesvirus latency
mailto:[email protected]
Cohrs
20) Apr 1, 2015 (W) Viral reproductive and congenital infections
Bowen
21) Apr 3, 2015 (F)
Landolt
Viral respiratory diseases- influenza
mailto:[email protected]
22) Apr 8, 2015 (W) Viral enteric diseases
mailto:[email protected]
MacNeil
23) Apr 10, 2015 (F) Mosquito-borne viral diseases
mailto:[email protected]
Powers
24) Apr 15, 2015 (W) Vector biology and arboviruses
Olson
25) Apr 17, 2015 (F) Innate immunity and the mosquito vector
Blair
26) Apr 22, 2015 (F) Prion diseases
mailto:[email protected]
Hoover
27) Apr 24, 2015 (F) Bats and zoonotic viral diseases
Schountz
28) Apr 29, 2015 (W) Viral hepatitis
mailto:[email protected]
Barton
29) May 1, 2015 (W) Rodent-borne zoonotic viral diseases
Schountz
30) May 6, 2015 (W) Antiviral Therapy
Geiss
mailto: [email protected]
31) May 8, 2015 (F) Vaccine and Antiviral product development
mailto:[email protected]
Pierro
32)
Olson/Quackenbush
Final Exam