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Afterload
15/11/10
Part I Notes
= left ventricular wall tension required to overcome resistance to ejection (impedance to
ejection of blood from the heart into the arterial circulation)
- developed as ventricular muscle fibres shorten during isovolumetric contraction & ejection
phases of systole
DETERMINED BY
-
Ventricular size
Ventricular volume
Chamber radius
Wall thickness
SVR
Aortic compliance
MANIPULATION IN ICU
- optimal fluid therapy to ensure adequate ventricular size, volume and radius (diastolic
volume)
- vasopressors: increase SVR
- vasodilators: decrease SVR
- IABP: decreases afterload
- replacement of aortic valve (emergently)
Jeremy Fernando (2010)