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Radial glial cells serve as precursors to neurons in the central nervous system and also provide a scaffold for radial neuronal migration. Progenitor cells in
the ventricular zone of the developing cerebral cortex have nuclei that migrate along the apical-basal axis as they progress through the cell cycle. Left:
During the G1 phase nuclei rise from the inner (apical) surface of the ventricular zone. During the S phase they reside in the outer (basal) third of the
ventricular zone. During the G2 phase they migrate apically, and mitosis occurs when the nuclei reach the ventricular surface. Right: During cell division
radial glial cells give rise to postmitotic neurons that migrate away from the ventricular zone using radial glial cells as a guide.
Source: Differentiation and Survival of Nerve Cells, Principles of Neural Science, Fifth Editon
Citation: Kandel ER, Schwartz JH, Jessell TM, Siegelbaum SA, Hudspeth AJ, Mack S. Principles of Neural Science, Fifth Editon; 2012 Available
at: http://mhmedical.com/ Accessed: April 29, 2017
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