Download Bio 256 Unit 4C - Iowa State University

Human Physiology Unit 4C:
Urinary: Glomerular Filtration
Supplemental Instruction
Iowa State University
Leader:
Course:
Instructor:
Date:
Paige Stieneke
BIOL 256
Dr. Karri Haen
April 10, 2013
Juxtaglomerular Apparatus
Two types of cells:
1. _____________________: Enlarged cells that lie next to the afferent (sometimes efferent) arteriole
a. Controls ____ and Na+ (reabsorption, secretion), therefore (increasing, decreasing) BP
2. _____________________: Contain granules, secrete the hormone ________ (to increase BP)
Glomerular Hydrostatic Pressure (PGC)
Bowman’s Capsule Hydrostatic Pressure (PBC)
Glomerular Osmotic Pressure (πGC)
Bowman’s Capsule Osmotic Pressure (πBC)
Glomerular Filtration Pressures
1. During the process of glomerular filtration, plasma is filtered out from the _______ and into the
_______________________.
2. Which two pressures push plasma against the walls of the capillaries? (i.e. favor filtration)
a.
b.
3. Which two pressures draws fluids into the capillaries? (i.e. oppose filtration)
a.
b.
Net Filtration Pressure (NFP)
1. Net Filtration Pressure =
2. NFP =
Supplemental Instruction
1060 Hixson-Lied Student Success Center v 294-6624 v www.si.iastate.edu
Glomerular Filtration Rate
1. What is the Glomerular Filtration Rate (GFR)?
2. What three factors affect the Glomerular Filtration Rate?
a.
b.
c.
3. Glomerular Filtration Imbalances
a. If needed substances are not reabsorbed, then GFR is too (high, low)
b. If everything is reabsorbed, including wastes, then GFR is too (high, low)
4. Which three mechanisms control or regulate the Glomerular Filtration Rate?
a.
I.
Intrinsic System
i. ___________________: Affects afferent arteriole constriction or dilation
ii. ___________________: Affects afferent arteriole constriction or dilation
b.
c.
Renin-Angiotensin System
1. Juxtaglomerular ______________________ release _________
2. Renin stimulates _______________________ (from liver) to produce ___________________
3. ________________________________________(from lungs) converts Angiotensin I to produce
_______________________
4. What is the function of Angiotensin II?
a. Stimulates adrenal cortex to release ________________ à conserves Na+ (Sodium
reabsorption causes water retention) which in turn conserves __________
b. Stimulates the posterior pituitary to release ________, also conserving water
c. Stimulates your hypothalamic neurons, causing _________
d. RESULT:
5. Is the Renin-Angiotensin System a positive or negative feedback mechanism?
Supplemental Instruction
1060 Hixson-Lied Student Success Center v 294-6624 v www.si.iastate.edu