* Your assessment is very important for improving the workof artificial intelligence, which forms the content of this project
Download Chromosomes Notes
Cancer epigenetics wikipedia , lookup
No-SCAR (Scarless Cas9 Assisted Recombineering) Genome Editing wikipedia , lookup
Molecular cloning wikipedia , lookup
Epigenetics of human development wikipedia , lookup
Point mutation wikipedia , lookup
DNA damage theory of aging wikipedia , lookup
Genealogical DNA test wikipedia , lookup
Site-specific recombinase technology wikipedia , lookup
Nucleic acid analogue wikipedia , lookup
Deoxyribozyme wikipedia , lookup
Primary transcript wikipedia , lookup
Cell-free fetal DNA wikipedia , lookup
DNA vaccination wikipedia , lookup
Epigenetics in stem-cell differentiation wikipedia , lookup
Nucleic acid double helix wikipedia , lookup
DNA supercoil wikipedia , lookup
Genomic library wikipedia , lookup
Epigenomics wikipedia , lookup
Therapeutic gene modulation wikipedia , lookup
Y chromosome wikipedia , lookup
Cre-Lox recombination wikipedia , lookup
Designer baby wikipedia , lookup
History of genetic engineering wikipedia , lookup
Polycomb Group Proteins and Cancer wikipedia , lookup
Extrachromosomal DNA wikipedia , lookup
Artificial gene synthesis wikipedia , lookup
Microevolution wikipedia , lookup
X-inactivation wikipedia , lookup
Vectors in gene therapy wikipedia , lookup
CHROMOSOMES DNA is a diffuse spaghetti-like mass called chromatin during interphase. Interphase is the non-dividing phase. DNA condenses into chromosomes when the cell is dividing. Chromosomes are xshaped structures containing two identical copies of DNA DNA wraps around histone proteins to maintain a compact structure. (Each cell has about 3m of DNA) Nonhistone proteins serve as scaffolding for DNA. ________________________________________________________________________________________________________________________________________________ CHROMOSOME STRUCTURE Chromatids are identical copies of DNA. The Centromere is the structure that holds two chromatids together until they divide. HOMOLOGOUS CHROMOSOMES Homologous chromosomes are 2 chromosomes that have the same genes. However, they will be different versions of the gene (alleles) You get one chromosome of the pair from each parent. ________________________________________________________________________________________________________________________________________________ AUTOSOMES & SEX CHROMOSOMES Humans normally have 46 chromosomes (23 pairs from each of our parents). 22 pairs are called autosomes. One pair is sex chromosomes. XX or XY Haploid (1N) cells (egg & sperm) have ½ as many chromosomes. Diploid (2N) cells (all others) have 46 chromosomes. _________________________________________________________________________________________________________________________________________________ _________________________________________________________________________________________________________________________________________________ KARYOTYPES A karyotype is a picture of the chromosomes in a dividing cell. They can be used to identify genetic diseases. THE CELL CYCLE A regular cycle of growth and division. Interphase is the longest phase in the cell cycle. During interphase the cell grows and prepares to divide. ________________________________________________________________________________________________________________________________________________ CELL DIVISION Mitosis: 1 parent and 2 daughter cells = 2N. Meiosis: 1 parent and 4 daughter cells = 1N. Photos from Modern Biology, Holt, Rinehart & Winston. 2002 unless otherwise noted.