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Virology–BiologyW3310/W4310Spring2016 ProfV.Racaniello StudyquestionsforLecture5–Attachmentandentry 1.Whymustvirusesattachtoreceptorstoentercells?Docellreceptorsexistsolelyfor virusentry? 2.Describehowicosahedralandenvelopedvirionsattachtocellreceptors. 3.Whyaretworeceptorssometimesrequiredforentryintoacell? 4.Whatarethedifferentwaysthatnucleicacidsexitanakedicosahedralcapsid?An envelopedvirusparticle? 5.Whymustfusionofviralandcellularmembranesberegulated?Namethreewaysby whichitisregulated. 6.Howdoestheviralorsubviralparticlemovewithinthecell?Doesdiffusionplaya role? 7.Areviralnucleicacidsalwaysreleasedfromthecapsid/nucleocapsidduringentry? If not,provideanexample. 8.MostDNAviralgenomesmustenterthenucleus.Howisthismovement accomplished?DoanyRNAvirusgenomesenterthenucleus?Ifso,howdotheycross? StudyquestionsW3310/43102016
