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It is not known whether norfloxacin is excreted in human milk. Other drugs in this class are secreted in human milk, therefore the decision to discontinue nursing or to discontinue the drug should be made (Prod Info Noroxin(R), 2000). Detectable amounts of codeine may appear in breast milk. The manufacturer notes that the levels are probably not clinically significant after usual therapeutic doses (Prod Info Tylenol(R) with Codeine, 2000). ELIMINATION HALF-LIFE: 1 to 4 hours for acetaminophen and 2.5 to 3 hours for codeine (Prod Info Tylenol(R) with Codeine, 2000).