Download BIOL 103 Syllabus w2017 - Queen`s Biology

BIOL 103
Introductory Biology of Organisms
Winter2017
CALENDARDESCRIPTION
Anintroductiontothebasicthemesandconceptsofmodernbiologyspanningorganizationallevelsfrom
organismstoecosystemsinanevolutionarycontext.
SCHEDULE
LectureSection1(DuncanMacArthur)–Monday10:30,Wednesday9:30,Friday8:30.
LectureSection2(BioSciAud)–Monday1:30,Wednesday12:30,Friday11:30.
LectureSection3(HumphreyAud)–Monday4:30,Wednesday3:30,Friday2:30.
Labs:SeeSOLUSforalistofvariouslabtimesandlocations
CONTACTINFO
Instructors
ProfsVirginiaWalkerandAdamChippindale
InstructorContact
Dr.Walker,Rm.2522BioSci
[email protected],ph:613-533-6123
Dr.Chippindale(coursecoordinator),2420BioSci
[email protected],ph:613-533-6139
OfficeHours
TBA
LabInstructor
RobSnetsinger([email protected])
LabInstructorContactInfo
Ph:613-533-6000ext77439,
Rm.2322ABioscience
Rob’sOfficeHours
Normally,9:30-11:30and1:30-3:30Mondayto
Friday
LearningObjectives
Justaseukaryoticcellsarecomplexandintegratedmachines,organismsarebuiltaroundthespecialization
ofcellsintotissuesandorgansthatgrow,differentiateandcommunicateinordertocompeteandachieve
reproductivesuccessasanintegratedunit.Biology103developsasolidunderstandingofhowananimalis
builtandinteractswiththeabioticandbioticenvironment;howitstissuesandorgansworktogetherto
maintainasteadystateoradaptinthefaceofchallengesfromstressandinfection.Evolutioniskeyto
understandingboththehistoryoflifeandorganismalfunction,andtheBiologyofOrganismsissteepedin
evolutionaryprinciplesateachlevelofbiologicalorganization,includingtheforcesthatdrivechangeingene
frequencieswithinpopulations.Finally,recognizinghowpopulationsofdifferentspeciesinteractin
communitiesandecosystemsisvitaltounderstandingandprotectingbioticdiversityfromlocaltoglobal
scales.Thus,althoughBiology103istitledIntroductoryBiologyofOrganisms,understandingtheorganism
requireszoominginandoutfromgenestoecosystems,andtravellingbackintimesowemaypredictthe
future.
LearningHours
2
Other
In-classhours
Thetableoflearninghoursisonlyaroughestimateofthetimerequiredforthecourse.A3.0unitcourse
wouldnormallyrequireatotalof110to130totallearninghoursandthiscoursewillfallwithinthatrange,
butofcourse,isdependentuponindividualvariation.
Teachingmethod
Averagehoursper
Numberofweeks
Totalhours
week
Lecture
3
12
36
Seminar
Laboratory
2
12
24
Tutorial
Practicum
Grouplearning
Individualinstruction Onlineactivity
2
12
24
Off-campusactivity
Privatestudy
3
13
39
Totalhoursontask
123
CourseOutline
A.
1.
2.
3.
4.
5.
TheMakingofOrganismsfromCells(Dr.Walker)
(Duration:thefirst6weeksoflectures;18lecturestotal)
IntracellularandExtracellularDigestion
Ageneralintroductiontothecourse,guidelines,expectationsandlabannouncementswillbemade.
Inaddition,intracellularandextracellulardigestionwillbeexaminedwithexamplesfromprotists,
fungiandmorecomplexmetazoans.
DigestionandAbsorption
Enzymesimportantfordigestionwillbeexplored,aswellasthespecificityofactionofselected
proteases,withmostexamplesfromhumans.
DigestionandProblems
Thediscussionofdigestiveenzymeswillbecontinued,andsomehumandiseasesassociatedwith
digestionwillbeexplored.
ExcretionandIonTransportI
Thenitrogenouswasteproblemwillbepresentedusingexamplesfromfish,insects,developingbirds
andhumans).
ExcretionandIonTransportII
Thehumankidneyandexcretorydiseaseswillbehighlighted.Knowledgeofkidneyfunctioncrucially
dependsontheunderstandingofosmoticregulationandiontransport.Examplesofpumpsrelevant
6.
7.
8.
9.
10.
11.
12.
13.
14.
16.
3
tothissectionincludedrugpumps,bilesaltexportpumpsandthecysticfibrosistransmembrane
conductanceregulator.
MovementandMuscleControl
Anintroductiontomovement(plants,protists,culturedcells)withemphasisonthevertebrate
skeletalmuscleswillbepresented.
NeuralTransmissionandNervousControlI
Theclasswillinvestigatethetransmissionofasignaldownaneuronandclassesofneural
transmittersusingthevertebrateasaprimarymodel.
Neuroscience
Furtherunderstandingofsynaptictransmissionofthesignalwillbeamplifiedbypractical
applicationsofneuroscience(e.g.insecticides,neurologicaldiseasesandtheirtreatments,poisons
producedbysnakes,fishandplants).Anoverviewofthecomparativephysiologyofnervoussystems
(e.g.cnidarians,annelids,mollusksandvertebrates)andofthebrainwillalsobepresented.
CirculatorySystems
Ageneralintroductiontocirculatorysystemsindiverseorganismswillbepresentedbutwithan
emphasisonmammaliancirculatorysystem.Thebloodclottingcascadeandvariousgeneticdiseases
associatedwiththecirculatorysystemwillbediscussed.
RespirationandGasExchange
Thetransportofoxygentothetissuesinvertebratesusingredbloodcells,andtransportofwaste
carbondioxideisthefocusofthelecture.Adaptationstohighaltitudesandembryonicdevelopment
willbeexploredaswellasadditionaldiseasesofthecirculatorysystem.
DefenceandImmunityI
Anintroductiontotherecognitionofselfanddefenceagainstpathogens(innatevs.adaptive)willbe
presented.Thehumoralresponseinmammalsisemphasizedinthisfirstlectureoftheseries.
ImmunityandImmunogenetics
Thecellularresponsetopathogens(TcellsandtheassemblyofTreceptors,MHCproteinsetc)will
bepresented,aswilltheconceptsofimmunetoleranceandhumandiseasesoftheimmunesystem.
ImmunityandCancer
Genomerearrangements(e.g.Burkett’slymphoma)inlymphocytesfollowfromperturbationsofthe
immunesystem.Therewillbeageneralreviewofthecausesofcancerswithasectiondevotedto
retroviruses.
EvadingtheImmuneSystem
AcasestudyofHIVwillbepresentedincludingthevirallifecycle,itsepidemiologyandthesocial
responsibilitiesofthedisease.TheskirmishesinthebattlebetweenHIVandtheimmunesystemas
wellastestedtherapies,andHIVresistancemechanismsmakeforafascinatingexploration.
DefenceinOtherOrganismsandanIntroductiontoHormones
Immunityininsectsandplantsisexplored,aswellasanintroductiontohormonesimportantin
development.
17.
18.
4
HormonesandEndocrineSystems
Developmentwillbefurtherexploredasanorchestrationofsteroidandpeptidehormonesynthesis
byendocrineglands.Practicalapplicationsofhormonestudiesincludingcheatinginathletic
performanceandanti-dopingmonitoring,fishbehavior,osmoregulationinhumans,andmineral
balanceinhumanswillbeusedasexamples.
PuttingitAllTogether:HomeostasisandReview
Hormone-associateddiseases,andabriefoverviewofhomeostasisanditsimportance,willbe
discussed.Participationinaguidedreviewofthecoursewillfollowwithexamplestaken
fromrecentnewsitemsassociatedwiththesubjectscoveredbythecourse.
B.
OrganismstoEcosystems(Dr.Chippindale)
(the6weeksoflecturesfollowingReadingWeek)
Week7.Introduction Therelevanceofevolution;theevidenceforevolution;naturalselectioninthelabandinthewild;thepace
ofevolutionarychange;evolution&diversity.
Week8.GenesinPopulations
Theforcesofevolutionarychange(selection,drift,migration,mutation);detectingevolution
Week9.EvolutionaryEnigmas
Sexandmulticellularity;originsofsex;originsofdifferentmatingtypesandgametes;consequencesof
separatesexes;sexualselection&conflict;theoriginoforganisms.
Week10.SpeciesandSpeciation
Speciesdefinitions;modesofspeciation;hybridzones;micro-versusmacroevolution.
Week11.Population&CommunityEcology
Lifehistorystrategies;populationgrowth;theniche,speciesinteractions–symbioses,mutualism,parasitism
etc.
Week12.Ecosystems&Conservation
Energyflow;productivity;elementalcycles;biodiversity;conservationbiology.
C.
5
LaboratoryExercises:
Informationonthelaboratoryexercisesisavailableinthelaboratorymanual,butislikelytoincludemuscle
physiology,respirationphysiology,andevolution
Textbooks/Readings
Website:http://www.queensu.ca/biology/undergrad/courses/course/courselistings.htmlCourseText
(required;second-handoldereditionsfineoruselibrarytexts):
CampbellBiology,CanadianEditionbyReece,Urry,Cainet.al.,2014,publishedbyPearson.
*Note:Accesstothepublisher’swebsiteisassociatedwiththetext(providedwithpurchaseofnewtext)
DepartmentofBiologywebsite:http://biology.queensu.ca
Datesanddetailsofreadingsandassignmentswillbeannouncedinclassand/orpostedonthecourse
websiteinOnQ.DatesanddetailsforlabactivitiessessionassignmentswillbepresentedinOnQand/orthe
labs.
GradingScheme
(ifthisischanged,amplenoticewillbegivenonthefirstdayofclassandpostedonOnQ)
Component
OnQtests(5)
Online/Connectorother
activities
Lab:Assignments(announced
inlab)
IClickeruse:mostlectures
FinalExam
Weight(%)
15%
7%
Date
TBA
TBA
35%
TBA
3%
40%
TBA
6
GradingMethod
Mostcomponents(e.g.exams,onlinequizzes)ofthiscoursewillreceivenumericalpercentagemarks.The
finalgradeyoureceiveforthecoursewillbederivedbyconvertingyournumericalcourseaveragetoaletter
gradeaccordingtoQueen’sOfficialGradeConversionScale.Othercomponentswillreceivelettergrades,
whichwillbetranslatedintonumericalequivalentsusingtheFacultyofArtsandScienceapprovedscale.
Students’courseaverageisthenconvertedtoafinallettergradeaccordingtoQueen’sOfficialGrade
ConversionScale:
Queen’sOfficialGradeConversionScale
NumericalCourse
Grade
Average(Range)
A+
90-100
A
85-89
A-
80-84
B+
77-79
B
73-76
B-
70-72
C+
67-69
C
63-66
C-
60-62
D+
57-59
D
53-56
D-
50-52
F
49andbelow
AcademicIntegrityandQueen’sCodeofConduct
Studentsareresponsibleforfamiliarizingthemselveswiththeregulationsconcerningacademicintegrityand
forensuringthattheirassignmentsandconductconformtotheprinciplesofacademicintegrity.Information
isavailableintheArtsandScienceCalendar(seeAcademicRegulation1-
http://www.queensu.ca/artsci/academic-calendars/regulations/academic-regulations,ontheArtsand
Sciencewebsite(seehttp://www.queensu.ca/artsci/academics/undergraduate/academic-integrity),andat
Biology’swebsite(http://www.queensu.ca/biology/undergrad/integrity.html)andfromtheinstructorofthis
course.Departuresfromacademicintegrityincludeplagiarism,useofunauthorizedmaterials,facilitation,
forgeryandfalsification,andareantitheticaltothedevelopmentofanacademiccommunityatQueen's.
Giventheseriousnessofthesematters,actionswhichcontravenetheregulationsonacademicintegrity
carrysanctionsthatcanrangefromawarningorthelossofgradesonanassignmenttothefailureofa
coursetoarequirementtowithdrawfromtheuniversity.
AccommodationPolicy,ExamConflicts,andOtherConflicts
Studentswhofeeltheyneedaccommodationsfordisabilitiesorextenuatingcircumstances,orhavea
conflictbetweenexamsorothercommitmentsshouldconsulttheBiologyDepartment’swebsitefordetails
abouthowtoproceed(http://www.queensu.ca/biology/undergrad/integrity.html).Ingeneral,theearliera
coursecoordinatorisapprisedofanextenuatingcircumstance,themorelikelyanaccommodationcanbe
made.Studentsareencouragedtobeproactiveinanticipatingdifficulties,whenitispossibletodoso.
7
Studentsmayapplytowriteamake-upordeferredexamiftheyhaveanexamconflictasdefinedinthe
AcademicRegulationsoftheFaculty(SeeArtsandScienceCalendarRegulation8-
http://www.queensu.ca/artsci/academic-calendars/regulations/academic-regulations).Inthiscase,the
studentshouldreporttotheExamsOfficefirsttoverifythatthereisagenuineexamconflict.Biology
professorswillnotconsideryoursituationtobeaconflictunlessitmeetsthecriteriasetoutbytheFaculty
ofArtsandSciences.
Studentsmayrequestamake-upordeferredexamiftheyhaveanexamconflictwithoff-campustravel
associatedwithafieldcourse(e.gBIOL-307/3.0or407/3.0)thatisheldduringthefallorwinterterms.
Copyright
Allmaterialpresentedisthepropertyoftheinstructor(s)unlessotherwisestatedorposted.Thirdparty
copyrightedmaterials(suchasbookchaptersandarticles)haveeitherbeenlicensedforuseinthiscourse,
havebeenprovidedbythetextbookpublishersforuseinthecourse,orfallunderanexceptionorlimitation
inCanadianCopyrightlaw.Copyingthismaterialfordistribution(e.g.uploadingmaterialtoacommercial
thirdpartywebsite)canleadtoaviolationofCopyrightlaw.Findoutmoreaboutcopyrightat
http://library.queensu.ca/copyright.
AccommodationofDisabilities
Queen'sUniversityiscommittedtoachievingfullaccessibilityforpersonswithdisabilities.Partofthis
commitmentincludesarrangingacademicaccommodationsforstudentswithdisabilitiestoensuretheyhave
anequitableopportunitytoparticipateinalloftheiracademicactivities.Ifyouareastudentwithadisability
andthinkyoumayneedaccommodations,youarestronglyencouragedtocontacttheDisabilityServices
Office(DSO)andregisterasearlyaspossible.Formoreinformation,includingimportantdeadlines,please
visittheDSOwebsiteat:http://www.queensu.ca/hcds/ds/