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Odor responses in the olfactory bulb. A. The axons from neurons in one epithelial zone with the same odorant receptor type usually converge to two
glomeruli, one on each side of the olfactory bulb. Here a probe specific for one odorant receptor gene labeled a glomerulus on the medial side (left) and
lateral side (right) of a mouse olfactory bulb. The probe hybridized to receptor messenger RNAs present in sensory axons in these coronal sections.
(Adapted from Ressler, Sullivan, and Buck 1994.)
B. This section of a rat olfactory bulb shows the uptake of radiolabeled 2-deoxglucose at multiple foci (red) following exposure of the animal to the odorant
methyl benzoate.
The
labeled
correspond
to numerous
glomeruli of
at Neural
different
locations
the olfactory bulb. (Reproduced, with permission, from
Source:
Smell
and foci
Taste:
The Chemical
Senses, Principles
Science,
FifthinEditon
Johnson, Farahbod, and Leon 2005.)
Citation: Kandel ER, Schwartz JH, Jessell TM, Siegelbaum SA, Hudspeth AJ, Mack S. Principles of Neural Science, Fifth Editon; 2012 Available
C. The olfactory bulb
has a precise map of Accessed:
odorant receptor
inputs
at: http://mhmedical.com/
June 11,
2017because each glomerulus is dedicated to only one type of receptor. The maps in the
two olfactoryCopyright
bulbs are©bilaterally
symmetrical
and
are
nearly
identical
2017 McGraw-Hill Education. All rights reservedacross individuals. The maps on the medial and lateral sides of each bulb are
similar, but slightly displaced along the dorsal-ventral and anterior-posterior axes.