Download Vocabulary deletion – inversion – translocation – nondisjunction

Vocabulary
deletion –
P. 239
3. Mutations can involve: a) __________ __________________
b) ___________ DNA __________________
inversion –
Chromosomal Mutations
P. 239
1. 2 ways to have a chromosomal mutation are: a) ____________ in the _____________
of a chromosome
b) ______ or _______ of a chromosome
translocation –
 2. Make sure you wrote complete definitions to the left….REREAD THEM to check for
completeness. YOU WILL NEED THEM FOR THE NEXT QUESTION!!!
nondisjunction –
Use Figure 12-6 and the definitions from this section to identify which type of mutation is
affecting the following cells.
BEFORE MUTATION:
AFTER MUTATION:
What is the problem here? ____________________
_________________________________________
Cell 1
____________________
Type of Mutation
Cell 2
____________________
Type of Mutation
Cell 3
____________________
Type of Mutation
Cell 4
____________________
Type of Mutation
What I can’t
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Vocabulary
Use the drawings from the previous page and Figure 12-6 on p. 239 to answer the following
questions.
1. Which cell is the only one that is undergoing meiosis?
#1
#2
#3
#4
(Circle one)
2. In the cell mentioned in #4 above, one ___________ receives an ____________ ________
of a chromosome, and another _______________ receives ________ ______________.
3. What disorder can a cell like #4 cause? (See Figure 12-7) __________ ________________
4. Why does the boy in the Figure 12-7 have that disorder?
5. What does this mean? (see Figure 12-7)
6. BONUS – How could this happen? Explain.
point mutation –
Gene Mutations
p. 240
¶1 – 1. What 3 things cause a point mutation?
a.
b.
c.
substitution –
2. A point mutation occurs _________ a ___________ _________ or other ___________
of DNA on a ___________________.
3. If a substitution mutation occurs, can it change the amino acid? YES or NO (circle one)
4. If a substitution mutation occurs, can it affect the protein? YES or NO (circle one)
What I can’t
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Vocabulary
p. 240
5. Looking at Figure 12-8, part a,
a. What amino acid should be there? _________________ ___________
b. Due to substitution, what amino acid is there? __________________
c. How did that happen? Explain.
deletion –
(not boldfaced in paragraph)
6. If a base or group of bases is DELETED, what can this loss cause?
_________________ ________________ of the remaining ___________ making
all the ___________ __________ downstream ___________.
7. What happens to the codons in a frameshift? Circle the correct answer.
stay the same or changes the codons after the frameshift mutation or changes the codons before the frameshift mutation
frameshift mutation –
8. Is a frameshift dangerous to us? YES or NO (circle one)
9. Explain the answer to #8.
10. In Figure 12-8b, what is causing the frameshift? (compare the “normal” to the
“frameshift”)
insertion mutation –
11. What type of mutation do you see in Figure 12-8b?
deletion or insertion or substitution (Circle one)
12. Which 2 mutations cause a frameshift mutation?
substitution or insertion or deletion (Circle two)
What I can’t
explain in my
own words