Download BDS Ist YEAR EXAMINATION 2008-09

MBBS II (Second) Professional Examination 2012-13
Course Code:MBS203
Paper ID: 0322410
Pharmacology-I
Time: 2 Hours 40 Minutes
Max Marks: 30
Note: Attempt all questions. Draw proper diagrams to support
your answer.
Part ‘B’
1.
Describe various mechanism of drug action with suitable
example.
(7)
2.
Write therapeutic approach to status epilepticus.
3.
(4+4)
a)
b)
Write pharmacological rational of:
H2 blockers in peptic ulcer
Diazepam in convulsion
(4+4)
a)
b)
Comment on following drug combination:
Diclofenac with Omeprazole
Levodopa with carbidopa
4.
(7)
MBBS II (Second) Professional Examination 2012-13
Roll No.
Student’s Name
Student’s Signature
Invigilator’s Signature
Course Code:MBS203
Paper ID: 0322410
Pharmacology-I
Part ‘A’
Time: 20 Minutes
Max Marks: 10
Note: 1. Attempt all questions and return this part of the question paper to the invigilator after 20 Minutes.
2. Please tick (√) correct one only. Cutting, overwriting or any other marking are not allowed.
3. For answering please use Ball- pen only.
a)
Adrenaline
Q.1
Pharmacokinetics is:
b)
Noradrenaline
a)
Study of drug movement in body
c)
Dopamine
b)
Study of drug effect
d)
Isoprenaline
c)
Study of pharmacogenetics
d)
None of the above
Q.7
Which antihistaminic is least sedative?:
a)
Promethazine
Q.2
A highly ionized drug :
b)
Chlorpheniramine
a.
Excreted by kidney
c)
Levocetrizine
b.
Cross placental barrier
d)
Hydroxyzine
c.
Well absorbed from GIT
Q.8
Pt. taking terfenadine with ketoconzole is
d.
Accumulate in cellular lipid
prone for:
a)
Cardiac arrhythmia
Q.3
Rate limiting step in Ach synthesis:
b)
CHF
a)
Choline acetyl transferase activity
c)
Toxicity of ketoconzole.
b)
Choline uptake by nerve ending
d)
None of the above
c)
Transport of Ach into vesicle
d)
Release of Ach from vesicle
Q.9
Which of the following is not an amide?:
Q.4.
Q.5
Q.6
Pralidoxime act by:
a)
Reactivating cholinesterase enzyme
b)
Promoting
synthesis
of
cholinesterase
c)
Promoting synthesis of Ach
d)
Direct action on cholinergic
receptor
Drug of choice for anaphylactic shock:
a)
Antihistamine
b)
Theophylline
c)
Corticosteroid
d)
Adrenaline
Which drug increases renal perfusion?:
a)
b)
c)
d)
Lignocaine
Procaine
Mepivacaine
Dibucaine
Q.10
Dissociative anaesthesia is produced by:
a)
Thiopentone
b)
Etomidate
c)
Ketamine
d
Propofol
Q.11
Barbiturates are:
a)
Enzyme inducers
b)
Enzyme inhibitors
c)
Have no effect on enzyme
d)
None of the above
P.T.O
Q.12
Antagonist of Benzodiazepine is:
a)
Nalorphine
b)
Carbamazepine
c)
Naloxone
d)
Flumazenil
Q.13
Drug of choice for seizures in pregnancy:
a)
MgSO4
b)
Sod. Valproate
c)
Phenobarbitone
d)
Phenytoin
Q.14
Phenytoin does not cause:
a)
Osteomalacia
b)
Gum hyperplasia
c)
Megaloblastic anaemia
d)
Weight gain
Q.15
Omalizumab is used in:
a)
Rheumatoid arthritis
b)
Bronchial asthma
c)
Psoriasis
d)
Myaesthenia
Q.16
Which of the following drug is leukotrien
antagonist?:
a)
Terbutaline
b)
Montelukast
c)
Na Cromoglycate
d)
Nedocromil
Q.17
Longest acting insulin is:
a)
Aspartate
b)
Lispro
c)
Glargine
d)
Glulisine
Q.18
Lactic acidosis is side effect of :
a)
Glipizide
b)
Phenformin
c)
Rapaglinide
d)
Pioglitazone
Q.19
Aromatase inhibitor is:
a)
Tamoxifen
b)
Letrazole
c)
Danazole
d)
Jaxane
Q.20
Uterine Contractions are suppressed by:
a)
Progesterone
b)
Testosterone
c)
Glucagon
d)
Thyroxine