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Name ______________________________ Class ___________________ Date __________________
SECTION 11-1 REVIEW
CONTROL OF GENE EXPRESSION
VOCABULARY REVIEW Explain the relationship between the terms in each
of the following pairs of terms.
1. regulator gene, repressor protein _______________________________________
__________________________________________________________________
2. operator, operon ___________________________________________________
__________________________________________________________________
3. intron, exon _______________________________________________________
__________________________________________________________________
4. transcription factor, enhancer _________________________________________
__________________________________________________________________
MULTIPLE CHOICE Write the correct letter in the blank.
_____ 1. A gene is expressed when it is
a. present in the genome of an individual.
b. prevented from interacting with RNA polymerase.
c. transcribed into mRNA.
d. duplicated during the replication of DNA.
_____ 2. In the lac operon of E. coli, lactose functions as
a. a promoter. b.an operator.
c. a repressor protein
d. an inducer.
_____ 3. In eukaryotic cells, transcription occurs
a. on parts of the DNA that are uncoiled. c.
b. only on introns.
d.
only on exons.
on all parts of the DNA.
_____ 4. Unlike gene expression in prokaryotes, gene expression in eukaryotes
a. cannot be regulated before transcription has occurred.
b. can be regulated after transcription has occurred.
c. does not involve promoters.
d. involves the transcription of groups of genes called operons.
_____ 5. Enhancers
a. code for proteins called inducers.
prokaryotic
b. must be located close to the genes
binding to they activate.
c.
are found only in
genomes.
d. facilitate transcription by
transcription factors.
Original content Copyright © by Holt, Rinehart and Winston. Additions and changes to the original content are the responsibility of the instructor.
Modern Biology
57
Control of Gene Expression
Name ______________________________ Class ___________________ Date __________________
SHORT ANSWER Answer the questions in the space provided.
1. What is an operon, and in what type of organism are operons found?
________________________________________________________________
________________________________________________________________
2. Describe what occurs during activation of the lac operon. ________________
________________________________________________________________
________________________________________________________________
3. Describe what occurs during repression of the lac operon. ________________
________________________________________________________________
4. Critical Thinking How does the absence of a nuclear envelope in prokaryotes
prevent prokaryotes from controlling gene expression by modifying RNA after
transcription?
________________________________________________________________
________________________________________________________________
STRUCTURES AND FUNCTIONS Use the figure to answer the following
questions.
1. The diagram below represents the lac operon in the presence of lactose. Label
each part of the diagram in the space provided.
2. If the regulator gene were deleted, how would this affect expression of the
structural genes? Explain your answer. _______________________________
________________________________________________________________
3. Is transcription of the structural genes activated or repressed under the
conditions shown above? Explain your answer. ________________________
________________________________________________________________
Original content Copyright © by Holt, Rinehart and Winston. Additions and changes to the original content are the responsibility of the instructor.
Modern Biology
58
Control of Gene Expression
Name ______________________________ Class ___________________ Date __________________
SECTION 11-2 REVIEW
GENE EXPRESSION IN
DEVELOPMENT AND CELL DIVISION
VOCABULARY REVIEW Distinguish between the terms in each of the
following pairs of terms.
1. homeobox, homeotic gene _________________________________________
________________________________________________________________
2. proto-oncogene, oncogene _________________________________________
________________________________________________________________
3. sarcoma, lymphoma ______________________________________________
________________________________________________________________
4. oncogene, tumor-suppressor gene ___________________________________
________________________________________________________________
MULTIPLE CHOICE Write the correct letter in the blank.
_____ 1. The expression of different genes in different cells of a multicellular
organism
a. contributes to the development of form in an organism.
b. causes the uncontrolled proliferation of cells.
c. is caused by the transfer of cells from one organism to another.
d. results from mutations that destroy normal gene functioning.
_____ 2. Homeoboxes are
a. found only in prokaryotes.
b. found only in Drosophila.
c. mutations that can have
devastating consequences on
development.
d. DNA sequences that regulate
patterns of development.
_____ 3. The major distinguishing characteristic of cancer is
a. uncontrolled cell division.
c. metastasis.
b. production of viruses.
d. tumor formation.
_____ 4. More than 85 percent of all lung cancers are caused by
a. asbestos. b.tobacco smoke. c. X rays.
d. ultraviolet light.
Original content Copyright © by Holt, Rinehart and Winston. Additions and changes to the original content are the responsibility of the instructor.
Modern Biology
59
Gene Expression in Development and Cell Division
Name ______________________________ Class ___________________ Date __________________
_____ 5. A gene whose normal function is to prevent uncontrolled cell division
is
a. an oncogene.
c. a homeotic gene.
b. a cancer gene.
d. a tumor-suppressor gene.
SHORT ANSWER Answer the questions in the space provided.
1. How do homeotic genes regulate development in Drosophila? ____________
________________________________________________________________
________________________________________________________________
2. What factors influence whether a person will develop cancer? _____________
________________________________________________________________
________________________________________________________________
3. How can viruses induce cancer? ____________________________________
________________________________________________________________
4. What are two key characteristics of cancer cells? _______________________
________________________________________________________________
5. Critical Thinking A great deal of research on the causes of and a possible
cure for cancer focuses on the genes that control the cell cycle. Why?
________________________________________________________________
________________________________________________________________
________________________________________________________________
________________________________________________________________
STRUCTURES AND FUNCTIONS Complete the flowchart below by filling in
the three boxes at the bottom.
Original content Copyright © by Holt, Rinehart and Winston. Additions and changes to the original content are the responsibility of the instructor.
Modern Biology
60
Gene Expression in Development and Cell Division