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Biology II—Chapter 12 Reading Guide—“The Cell Cycle” 1. What is the continuity of life based on? 2. What is a cell’s genetic information called? (not DNA) 3. How are DNA molecules packaged into cells? 4. What are human body cells called? What are reproductive cells called? 5. What is nuclear division called? What is cytoplasmic division called? 6. List the phases if the cell cycle (include the subphases of interphase) and briefly tell what is happening during each. 7. What are the 5 subphases of mitosis? Briefly give an overview of each. 8. Describe the difference in cytokinesis in animal cells and plant cells. 9. How do prokaryotes reproduce? 10. Since prokaryotes do not have mitotic spindles, what was the hypothesis formed during the 1960s explaining how daughter cells are separated during division? How has that hypothesis been updated? 11. What controls the sequential events of the cell cycle? 12. What do checkpoints in the cell cycle do? Where are the 3 major checkpoints found? 13. What does it mean that cancer cells don’t exhibit density-dependent inhibition? 14. What is transformation in cells? 15. What may happen if a transformed cell evades destruction by the immune system? 16. What is the difference between benign and malignant tumors? 17. Name 3 ways malignant tumors are abnormal. 18. If cancer cell separate from the original tumor where may they spread? 19. What is it called when cancer cells spread from their original site? 20. What are possible treatments for this?