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B2: Enzymes Spot the mistakes! Structure of digestive system Food will first enter the mouth where it will be chemically digested by the teeth into smaller pieces allowing there to be a smaller surface area for the enzyme amylase to work on. Amylase breaks down starch into maltose ( and then into glucose ) and is produced by the pituitary glands. Food passes by peristalsis (waves of muscle contractions) into the duodenum and form there into the stomach. The stomach churns the food and produces sulphuric acid which breaks down protein molecules into fatty acids. The food then passes into the small intestine where absorption takes place. Absorption is the breakdown of large molecules into smaller molecules. Finally the food passes into the large intestine where water is absorbed into the bladder. Enzyme structure Enzymes are sometimes also called biological catalysts. They are made of carbohydrate molecules and fold up in a particular way to produce an inactive site. The molecule (such as starch) which they break down is called a substance. All enzymes are specific meaning that they will only break down (absorb) one type of molecule. E.g amylase will only break down starch into glucose. Enzymes can be damaged by high temperatures – we called this saturated. Effect of temperature and pH on reaction rate As the temperature of a reaction increases the rate increases. This is because the molecules involved ( the enzyme and pass rate) move more slowly and collide less often. This only occurs up a certain temperature however (called the optimum). If the temperature increases too much then the structure of the enzyme’s active site will alter and the substrate will fit in. That is why it is important for our bodies to maintain a constant temperature (around 45 degrees C.) pH can also affect the rate of reactions involving enzymes. Most enzymes prefer pH 11 (neutral) however some enzymes work better at low pH (acidic) such as pepsin found in the small intestine. Making use of enzymes For years now we have been able to use detergents to help us wash our dishes and our clothes. Biological washing powders take advantage of using enzymes because it means we can wash clothes at higher temperatures. The biological washing powder contains digestive enzymes such as amylase which breaks fat down into fatty acids and glycerol and proteases which break proteins down into glucose. Baby foods contain proteases which pre-digest some of the food so that amino acids are available to the babies sooner and it can be used in the production of fuels and corn syrup.