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StanfordEncyclopedia_2016_Inheritance
... existence of non-genetic inheritance, and its significance for evolutionary accounts, these researchers argue against separating these phenomena into multiple channels or systems of inheritance (Griffiths & Gray 2001): Inheritance phenomena are so intertwined in their effects on development, and eac ...
... existence of non-genetic inheritance, and its significance for evolutionary accounts, these researchers argue against separating these phenomena into multiple channels or systems of inheritance (Griffiths & Gray 2001): Inheritance phenomena are so intertwined in their effects on development, and eac ...
Reprint
... and for a broad range of phenotypic traits (Avital & Jablonka 2000; Jablonka & Lamb 1995, 2005; Youngson & Whitelaw 2008). In plants, researchers have long recognized that environmental influences can be transmitted across generations ( Jablonka & Lamb 1995, Johannes et al. 2008). Likewise, in animal ...
... and for a broad range of phenotypic traits (Avital & Jablonka 2000; Jablonka & Lamb 1995, 2005; Youngson & Whitelaw 2008). In plants, researchers have long recognized that environmental influences can be transmitted across generations ( Jablonka & Lamb 1995, Johannes et al. 2008). Likewise, in animal ...
Health outcomes of children born after IVF/ICSI: a review of current
... organ development and function in developing organisms (Barker, 1995). The resulting physiological, metabolic and endocrine changes can be persistent and may predispose children to increased susceptibility to disease in later life. It remains to be seen whether assisted reproduction procedures affec ...
... organ development and function in developing organisms (Barker, 1995). The resulting physiological, metabolic and endocrine changes can be persistent and may predispose children to increased susceptibility to disease in later life. It remains to be seen whether assisted reproduction procedures affec ...
Defining characteristics of Tn5 Transposase non
... recombinases and retroviral integrases. Two of the three domains of the bacteriophage Mu Tnp (MuA) independently bind DNA non-specifically. Filter binding experiments with proteolytic fragments of MuA reveal that the N-terminal 26 amino acids of domain III binds supercoiled DNA nonspecifically (3) a ...
... recombinases and retroviral integrases. Two of the three domains of the bacteriophage Mu Tnp (MuA) independently bind DNA non-specifically. Filter binding experiments with proteolytic fragments of MuA reveal that the N-terminal 26 amino acids of domain III binds supercoiled DNA nonspecifically (3) a ...
Assessing the Probative Value of DNA Evidence
... jurisdictions. It goes without saying that the laws of probability, unlike the laws of the land, are valid irrespective of geography. It would be artificial and sometimes misleading when describing criminal litigation to avoid any reference whatsoever to legal precepts and doctrines, and we have not ...
... jurisdictions. It goes without saying that the laws of probability, unlike the laws of the land, are valid irrespective of geography. It would be artificial and sometimes misleading when describing criminal litigation to avoid any reference whatsoever to legal precepts and doctrines, and we have not ...
2. Assessing the probative value of DNA evidence
... jurisdictions. It goes without saying that the laws of probability, unlike the laws of the land, are valid irrespective of geography. It would be artificial and sometimes misleading when describing criminal litigation to avoid any reference whatsoever to legal precepts and doctrines, and we have not ...
... jurisdictions. It goes without saying that the laws of probability, unlike the laws of the land, are valid irrespective of geography. It would be artificial and sometimes misleading when describing criminal litigation to avoid any reference whatsoever to legal precepts and doctrines, and we have not ...
Arabidopsis onset of leaf death mutants identify a regulatory
... Under these induction conditions distinct sets of SAGs are induced, suggesting the existence of a complex regulatory network. The complexity is further shown by a recent screening for SAGs which takes advantage of an enhancer trap system (He et al., 2001). In addition, plant hormones have been impli ...
... Under these induction conditions distinct sets of SAGs are induced, suggesting the existence of a complex regulatory network. The complexity is further shown by a recent screening for SAGs which takes advantage of an enhancer trap system (He et al., 2001). In addition, plant hormones have been impli ...
Charge Transport in DNA - Insights from
... the overstretching profile of DNA was attributed to force-induced dehybridization based on thermodynamic observations.[26] Since then, reports have been constantly appearing against,[27] as well as in favor of the thermally induced melting.[28] Importantly, the nature of the overstretched state of DN ...
... the overstretching profile of DNA was attributed to force-induced dehybridization based on thermodynamic observations.[26] Since then, reports have been constantly appearing against,[27] as well as in favor of the thermally induced melting.[28] Importantly, the nature of the overstretched state of DN ...
Telomere maintenance without telomerase
... Dierent telomeres in post-senescent survivors exhibited variable lengths, often with tract lengths longer than telomeres of a telomerase-pro®cient strain. However, these elongated telomeres still exhibited the same gradual shortening observed during the initial senescence of a newly generated telom ...
... Dierent telomeres in post-senescent survivors exhibited variable lengths, often with tract lengths longer than telomeres of a telomerase-pro®cient strain. However, these elongated telomeres still exhibited the same gradual shortening observed during the initial senescence of a newly generated telom ...
The daily rhythm of mice
... established [12]. These mice had a slightly shorter period length than their wild-type controls. In further experiments it was found that NPAS2, a true homolog [13], compensates for the lack of functional CLOCK protein in the SCN [14]. Consequently, double knock out mice, by contrast to the individu ...
... established [12]. These mice had a slightly shorter period length than their wild-type controls. In further experiments it was found that NPAS2, a true homolog [13], compensates for the lack of functional CLOCK protein in the SCN [14]. Consequently, double knock out mice, by contrast to the individu ...
Mechanistic Comparison of High-Fidelity and Error
... 1.1. Scope of This Review Discovered in the early 1970s, DNA polymerase β (Pol β) was the first mammalian DNA repair polymerase to be characterized. Its relatively small size (39 kD) and the fact that it lacks an exonuclease proofreading activity make it a tractable system for studying the mechanism ...
... 1.1. Scope of This Review Discovered in the early 1970s, DNA polymerase β (Pol β) was the first mammalian DNA repair polymerase to be characterized. Its relatively small size (39 kD) and the fact that it lacks an exonuclease proofreading activity make it a tractable system for studying the mechanism ...
Waddington`s Legacy in Development and
... mental pathways to produce standard pheWaddington's early interests in theoreti- notypes despite environmental or genetic cal biology, fostered in the Theoretical Biol- influences that would otherwise disrupt ogy Club, were manifested in his editorship development. It is the buffering of develof a f ...
... mental pathways to produce standard pheWaddington's early interests in theoreti- notypes despite environmental or genetic cal biology, fostered in the Theoretical Biol- influences that would otherwise disrupt ogy Club, were manifested in his editorship development. It is the buffering of develof a f ...
RHD - Labex
... samples was performed using the Free Fetal DNA Kit® RhD (by using exon 5, 7 and 10) ...
... samples was performed using the Free Fetal DNA Kit® RhD (by using exon 5, 7 and 10) ...
PDF
... have been developing head to head to achieve nowadays a remarkable level of sophistication. They have their own unique advantages but, largely, offer similar capabilities and require the same workflow. The main advantage of optical tweezers is the ease with which single beads can be manipulated and ...
... have been developing head to head to achieve nowadays a remarkable level of sophistication. They have their own unique advantages but, largely, offer similar capabilities and require the same workflow. The main advantage of optical tweezers is the ease with which single beads can be manipulated and ...
SALSA MLPA KIT ME003-A1 Tumor suppressor-3 - MRC
... islands upstream of genes for which an altered methylation status in one or more types of tumours has been reported in literature. In case interesting results are obtained by users, it is possible to develop methylation kits specific for a certain tumour in collaboration with MRC-Holland. Interpreta ...
... islands upstream of genes for which an altered methylation status in one or more types of tumours has been reported in literature. In case interesting results are obtained by users, it is possible to develop methylation kits specific for a certain tumour in collaboration with MRC-Holland. Interpreta ...
Imprinting and Seed Development
... nutrients from the maternal parent to the endosperm and thus are likely to be a site of parental conflict and subject to parentof-origin effects. This phenotype, however, contradicts the hypothesis that paternal genomic excess will be associated with an increased transfer of nutrients from mother to ...
... nutrients from the maternal parent to the endosperm and thus are likely to be a site of parental conflict and subject to parentof-origin effects. This phenotype, however, contradicts the hypothesis that paternal genomic excess will be associated with an increased transfer of nutrients from mother to ...
Joseph L. Izzo, Jr Answer the Genetic Riddle Aging and Systolic
... hypothetical approach to the deeply intertwined relationship between hypertension and aging in humans. He describes existing evidence for 3 different hypotheses that might explain why blood pressure increases with age: the “fetal origin hypothesis,” which holds that a disorder of intrauterine growth ...
... hypothetical approach to the deeply intertwined relationship between hypertension and aging in humans. He describes existing evidence for 3 different hypotheses that might explain why blood pressure increases with age: the “fetal origin hypothesis,” which holds that a disorder of intrauterine growth ...
Classification of colorectal cancer based on correlation of clinical
... subset of CRCs without APC mutation is unproven. presence of unexp ect ed genetic s ignatures In addition to the absence of adenoma-specific mutations, sporadic MSI-H CRCs are characterized by alterations, specifically extensive DNA methylation and BRAF mutation, that are not only rare in sporadic a ...
... subset of CRCs without APC mutation is unproven. presence of unexp ect ed genetic s ignatures In addition to the absence of adenoma-specific mutations, sporadic MSI-H CRCs are characterized by alterations, specifically extensive DNA methylation and BRAF mutation, that are not only rare in sporadic a ...
Developmental Validation of the Quantifiler Real-Time
... The fluorogenic 5 nuclease assay process can be summarized as follows. At the start of PCR thermal cycling, all TaqMan probe molecules are intact, and the close physical proximity of the dye and quencher suppresses the fluorescence of the dye molecules by Förster-type energy transfer (14,15). Duri ...
... The fluorogenic 5 nuclease assay process can be summarized as follows. At the start of PCR thermal cycling, all TaqMan probe molecules are intact, and the close physical proximity of the dye and quencher suppresses the fluorescence of the dye molecules by Förster-type energy transfer (14,15). Duri ...
Harvey ras (H-ras) Point Mutations Are Induced by 4
... induced human malignancies closely associated with tobacco expo sure and alcohol consumption (1, 2). To define the molecular events involved in oral squamous mucosa neoplastic transformation, we have established a murine model which mimics human oropharyngeal SCCs using the chemical carcinogen, 4NQO ...
... induced human malignancies closely associated with tobacco expo sure and alcohol consumption (1, 2). To define the molecular events involved in oral squamous mucosa neoplastic transformation, we have established a murine model which mimics human oropharyngeal SCCs using the chemical carcinogen, 4NQO ...
Epigenetic Regulation ofbdnfGene Transcription in the
... is in a highly methylated or unmethylated basal state, the two different primer sets will be preferentially sensitive to alterations in methylation (Li and Dahiya, 2002). For example, a specific CpG island that is highly methylated in the basal state is much more likely to reveal demethylation chang ...
... is in a highly methylated or unmethylated basal state, the two different primer sets will be preferentially sensitive to alterations in methylation (Li and Dahiya, 2002). For example, a specific CpG island that is highly methylated in the basal state is much more likely to reveal demethylation chang ...
Replication timing as an epigenetic mark
... during ESC differentiation to neural precursor cells (NPCs) revealed changes across ~20% of the mouse genome.10 Importantly, the replication-timing changes that occurred were nearly identical using two different neural differentiation protocols and three cell lines. The ~20% changes seen are certain ...
... during ESC differentiation to neural precursor cells (NPCs) revealed changes across ~20% of the mouse genome.10 Importantly, the replication-timing changes that occurred were nearly identical using two different neural differentiation protocols and three cell lines. The ~20% changes seen are certain ...