Enteric Glia - Department of Physiology
... and these neurons communicate among themselves using all known major classes of neurotransmitters found in the brain. Enteric neurons form integrative circuits that are capable of directly determining the moment-to-moment behaviors of the intestine in the absence of signals from central nervous syst ...
... and these neurons communicate among themselves using all known major classes of neurotransmitters found in the brain. Enteric neurons form integrative circuits that are capable of directly determining the moment-to-moment behaviors of the intestine in the absence of signals from central nervous syst ...
Author`s personal copy
... site so that nursing behavior can occur. [Of course, if the pups are already located in an adequate nest, then the return of the mother to the nest after a period of absence can also be considered an appetitive approach response.] Therefore, we would like to categorize pup-seeking and retrieval beha ...
... site so that nursing behavior can occur. [Of course, if the pups are already located in an adequate nest, then the return of the mother to the nest after a period of absence can also be considered an appetitive approach response.] Therefore, we would like to categorize pup-seeking and retrieval beha ...
the Report - The Lasker Foundation
... Practically speaking, this means that visual acuity is reduced despite a normal structural eye examination due to the presence of at least one amblyopia risk factor early in life. These risk factors include deprivation (induced by congenital cataract or ptosis, for example), manifest strabismus of ...
... Practically speaking, this means that visual acuity is reduced despite a normal structural eye examination due to the presence of at least one amblyopia risk factor early in life. These risk factors include deprivation (induced by congenital cataract or ptosis, for example), manifest strabismus of ...
JAMA SIDS
... to the lack of understanding of the basic biological mechanisms. We have proposed the triple risk model,8 which suggests that sudden death results when 3 factors impinge on the infant simultaneously: (1) an underlying vulnerability; (2) an exogenous stressor (eg, prone sleep position, bed sharing); ...
... to the lack of understanding of the basic biological mechanisms. We have proposed the triple risk model,8 which suggests that sudden death results when 3 factors impinge on the infant simultaneously: (1) an underlying vulnerability; (2) an exogenous stressor (eg, prone sleep position, bed sharing); ...
CURRICULUM VITAE - Test - University of South Florida
... GRANT AWARDS R01HL109025 5/21/12 to 4/30/16 NIH/NHLBI Mechanisms of Swallow Neural Control (2012-2016) The goal of this project is to determine (i) how the respiratory neural network generates the swallow breathing pattern during the pharyngeal phase of swallowing, and (ii) mechanisms for respirator ...
... GRANT AWARDS R01HL109025 5/21/12 to 4/30/16 NIH/NHLBI Mechanisms of Swallow Neural Control (2012-2016) The goal of this project is to determine (i) how the respiratory neural network generates the swallow breathing pattern during the pharyngeal phase of swallowing, and (ii) mechanisms for respirator ...
Gastric Effects of Cholecystokinin and Its Interaction with Leptin on
... Stimulation and Recording Methods. A suction microelectrode was placed on the gastric vagal branch from the subdiaphragmatic vagi for electrical stimulation and units in the medial subnucleus of the NTS receiving gastric vagal inputs were evaluated in this study. The gastric vagal fibers were stimul ...
... Stimulation and Recording Methods. A suction microelectrode was placed on the gastric vagal branch from the subdiaphragmatic vagi for electrical stimulation and units in the medial subnucleus of the NTS receiving gastric vagal inputs were evaluated in this study. The gastric vagal fibers were stimul ...
Calcium Transients in the Garter Snake Vomeronasal Organ
... transients in retrogradely labeled snake vomeronasal (VN) neurons. A shows a video image illustrating the selective staining of VN neurons with Ca2⫹ Green after retrograde transport of this dye from their axonal terminals in the accessory olfactory bulb (AOB). Observe the labeling in the cell bodies ...
... transients in retrogradely labeled snake vomeronasal (VN) neurons. A shows a video image illustrating the selective staining of VN neurons with Ca2⫹ Green after retrograde transport of this dye from their axonal terminals in the accessory olfactory bulb (AOB). Observe the labeling in the cell bodies ...
Wild type human TDP-43 potentiates ALS-linked mutant TDP
... defective RNA processing or aberrant assembly of these aggregation prone proteins [16, 17] are mechanistic contributors in the pathogenesis of ALS. TDP-43 is a 414 amino acid protein, consisting of two RNA recognition motifs (RRM1 and RRM2) [18, 19], a nuclear import and export signal [20], and a gl ...
... defective RNA processing or aberrant assembly of these aggregation prone proteins [16, 17] are mechanistic contributors in the pathogenesis of ALS. TDP-43 is a 414 amino acid protein, consisting of two RNA recognition motifs (RRM1 and RRM2) [18, 19], a nuclear import and export signal [20], and a gl ...
Selective stimulation of the subthalamic nucleus in Parkinson`s
... non-human primate animal model of PD shed new light on the pathophysiological mechanisms of the disease. An important discovery was that in this animal model of PD the STN neurons were hyperactive and showed bursty firing properties (Bergman, et al., 1994, Miller and DeLong, 1987), which was later a ...
... non-human primate animal model of PD shed new light on the pathophysiological mechanisms of the disease. An important discovery was that in this animal model of PD the STN neurons were hyperactive and showed bursty firing properties (Bergman, et al., 1994, Miller and DeLong, 1987), which was later a ...
A decade of the anaphase-promoting complex in the nervous system
... the anaphase-promoting complex (Zachariae et al. 1998; Kramer et al. 2000). Characterization of the functions and regulation of Cdh1–APC and Cdc20–APC in dividing cells has provided invaluable clues for our understanding of the novel functions and mechanisms of the anaphasepromoting complex in the n ...
... the anaphase-promoting complex (Zachariae et al. 1998; Kramer et al. 2000). Characterization of the functions and regulation of Cdh1–APC and Cdc20–APC in dividing cells has provided invaluable clues for our understanding of the novel functions and mechanisms of the anaphasepromoting complex in the n ...
[ H]GABA and - The University of Sydney
... µM) had no significant effect on the potassium3 stimulated release of [ H]GABA in the spinal cord, cortex, and retina (Table 1). Preincubation of cerebellar and retinal slices with unlabeled βalanine (100 µM) to block uptake of GABA into ...
... µM) had no significant effect on the potassium3 stimulated release of [ H]GABA in the spinal cord, cortex, and retina (Table 1). Preincubation of cerebellar and retinal slices with unlabeled βalanine (100 µM) to block uptake of GABA into ...
Neurotransmitters, Drugs and Brain Function Wiley
... effects of a neurotransmitter and second, since only the excitatory effects of ACh at the neuromuscular junction fulfil the original definition of a neurotransmitter in transmitting excitation, either acetylcholine cannot be considered to be a neurotransmitter in the heart, despite its effects, or t ...
... effects of a neurotransmitter and second, since only the excitatory effects of ACh at the neuromuscular junction fulfil the original definition of a neurotransmitter in transmitting excitation, either acetylcholine cannot be considered to be a neurotransmitter in the heart, despite its effects, or t ...
Interactions between amygdala central nucleus and the ventral
... scoring, many of the video tapes were scored by multiple observers, who agreed on 95% of > 10 000 joint observations. The number of observations scored as rearing was divided by the total number of observations in a scoring period to form the measure ‘‘% rearing’. Because the number of observations ...
... scoring, many of the video tapes were scored by multiple observers, who agreed on 95% of > 10 000 joint observations. The number of observations scored as rearing was divided by the total number of observations in a scoring period to form the measure ‘‘% rearing’. Because the number of observations ...
INVESTIGATING THE SOPHISTICATION OF LONG-LATENCY UPPER LIMB
... Although this theory can explain how people move in the world, it does not specifically describe how this control process is implemented by the nervous system. In this thesis, we propose and explore one physiological implication of this theory. Specifically, we hypothesize that rapid feedback respon ...
... Although this theory can explain how people move in the world, it does not specifically describe how this control process is implemented by the nervous system. In this thesis, we propose and explore one physiological implication of this theory. Specifically, we hypothesize that rapid feedback respon ...
Spatial cognition, body representation and affective processes
... be refined in order to better assess what participants are doing when they recall from memory previously experienced vestibular sensations. As pointed out by zu Eulenburg et al. (2013a), they used a non-visual first-person strategy that differed from similar mental body transformation tasks, which r ...
... be refined in order to better assess what participants are doing when they recall from memory previously experienced vestibular sensations. As pointed out by zu Eulenburg et al. (2013a), they used a non-visual first-person strategy that differed from similar mental body transformation tasks, which r ...
Local Field Potentials Related to Bimanual Movements in the
... potentials in motor cortex has focused on the relationship of synchronous oscillations to movement and to single unit activity (Sanes and Donoghue, 1993;Eckhorn and Obermueller, 1993;Murthy and Fetz, 1996a;Baker et al., 1999), but the character of the evoked potential in this area and its relationsh ...
... potentials in motor cortex has focused on the relationship of synchronous oscillations to movement and to single unit activity (Sanes and Donoghue, 1993;Eckhorn and Obermueller, 1993;Murthy and Fetz, 1996a;Baker et al., 1999), but the character of the evoked potential in this area and its relationsh ...
Molecules and circuits involved in nicotine addiction: The many
... 2010; Gotti et al., 2010; Pons et al., 2008). Taken together, a combination of pharmacological, molecular genetic, electrophysiological, neurochemical and behavioral approaches has identified a4/a6/ b2* nAChRs in DA neurons of the VTA as essential for nicotine reinforcement, and suggests an important ...
... 2010; Gotti et al., 2010; Pons et al., 2008). Taken together, a combination of pharmacological, molecular genetic, electrophysiological, neurochemical and behavioral approaches has identified a4/a6/ b2* nAChRs in DA neurons of the VTA as essential for nicotine reinforcement, and suggests an important ...
The Role of Kv7 in Peripheral Neurons
... functional role of each Kv7 subunits within the peripheral sensory system have not been fully elucidated. In this thesis, I first investigate the expression pattern of Kv7.5 with immunohistochemical techniques, which allow me to show that Kv7.5 is localized in the axons of the Remak bundles (unmyeli ...
... functional role of each Kv7 subunits within the peripheral sensory system have not been fully elucidated. In this thesis, I first investigate the expression pattern of Kv7.5 with immunohistochemical techniques, which allow me to show that Kv7.5 is localized in the axons of the Remak bundles (unmyeli ...
Decreased cohesin in the brain leads to defective synapse
... the disruption of chromosomal architecture by malfunctioning cohesin; however, evidence for this hypothesis is lacking. We postulated that epigenetic control of gene expression by cohesin is required for normal brain development and higher brain function. Here, we show that abnormally low cohesin ex ...
... the disruption of chromosomal architecture by malfunctioning cohesin; however, evidence for this hypothesis is lacking. We postulated that epigenetic control of gene expression by cohesin is required for normal brain development and higher brain function. Here, we show that abnormally low cohesin ex ...
neuropathology of dopamine systems in schizophrenia
... black/brown pigmentation that accumulates in the cytoplasm of mesodiencephalic dopaminergic neurons. This pigmentation is due to the presence of neuromelanin, which is a byproduct of the metabolism of dopamine, giving the SN its distinct dark color (Double et al., 2000; Zecca et al., 2008). Within t ...
... black/brown pigmentation that accumulates in the cytoplasm of mesodiencephalic dopaminergic neurons. This pigmentation is due to the presence of neuromelanin, which is a byproduct of the metabolism of dopamine, giving the SN its distinct dark color (Double et al., 2000; Zecca et al., 2008). Within t ...
Novelty exploration training tasks - Repositório da Universidade de
... The rostral ventrolateral medulla (RVLM) is a medullar sympathoexcitatory area of the central autonomic network, which plays a crucial role in essential hypertension pathophysiology. Physiologically, RVLM has a key role in peripheral sympathetic tone generation. Its neurons monosynaptically project ...
... The rostral ventrolateral medulla (RVLM) is a medullar sympathoexcitatory area of the central autonomic network, which plays a crucial role in essential hypertension pathophysiology. Physiologically, RVLM has a key role in peripheral sympathetic tone generation. Its neurons monosynaptically project ...
The Role of Temporal Structure in Human Vision
... human visual systems to simplify the grouping of local features into global forms and to promote the segregation of those forms from their backgrounds. Indeed, grouping and figure/ground segregation have constituted two of visual perception’s most enduring, widely studied problems. Dating back to th ...
... human visual systems to simplify the grouping of local features into global forms and to promote the segregation of those forms from their backgrounds. Indeed, grouping and figure/ground segregation have constituted two of visual perception’s most enduring, widely studied problems. Dating back to th ...
PHYSIOLOGY OF PAIN
... pain nerve fibers. This action potential is transmitted to the spinal cord and makes a synaptic connection in lamina I and/or II. The cell bodies of nociceptors are mainly in the dorsal root and trigeminal ganglia. No nociceptors are found inside the CNS. Nociceptors are not uniformly sensitive. The ...
... pain nerve fibers. This action potential is transmitted to the spinal cord and makes a synaptic connection in lamina I and/or II. The cell bodies of nociceptors are mainly in the dorsal root and trigeminal ganglia. No nociceptors are found inside the CNS. Nociceptors are not uniformly sensitive. The ...
Neck Muscle Responses to Stimulation of Monkey Superior
... to keep their gaze within a computer-controlled fixation window (between 3 ⫻ 3 to 5 ⫻ 5° depending on FP position) for between 800 and 1,500 ms. SC stimulation (variable duration, described in the following text) was delivered on 80 –90% of all trials between 500 and 1,000 ms after the onset of fixa ...
... to keep their gaze within a computer-controlled fixation window (between 3 ⫻ 3 to 5 ⫻ 5° depending on FP position) for between 800 and 1,500 ms. SC stimulation (variable duration, described in the following text) was delivered on 80 –90% of all trials between 500 and 1,000 ms after the onset of fixa ...