Message in a bottle: small signalling peptide
... In the Arabidopsis genome, over 600 putative receptor-like kinase proteins have been detected (Shiu and Bleecker, 2001), while over 1000 putative small signalling peptide sequences can be recognized (Lease and Walker, 2006). There are several ways to explain this seeming overabundance of putative sm ...
... In the Arabidopsis genome, over 600 putative receptor-like kinase proteins have been detected (Shiu and Bleecker, 2001), while over 1000 putative small signalling peptide sequences can be recognized (Lease and Walker, 2006). There are several ways to explain this seeming overabundance of putative sm ...
Figure 2 - Trace: Tennessee Research and Creative Exchange
... In order to ensure their survival, bacteria must sense and adapt to a variety of environmental signals. Motile bacteria are able to orient their movement in a chemical gradient by chemotaxis. During chemotaxis, environmental signals are detected by chemotaxis receptors and are propagated via a signa ...
... In order to ensure their survival, bacteria must sense and adapt to a variety of environmental signals. Motile bacteria are able to orient their movement in a chemical gradient by chemotaxis. During chemotaxis, environmental signals are detected by chemotaxis receptors and are propagated via a signa ...
Full PDF
... matrix (ECM) and innate immune receptors in regulating noninfectious lung injury and repair. The ECM plays an important role in regulating the host response to lung injury. Accumulation of ECM can be seen during tissue injury following a variety of insults such as those that occur in the adult respi ...
... matrix (ECM) and innate immune receptors in regulating noninfectious lung injury and repair. The ECM plays an important role in regulating the host response to lung injury. Accumulation of ECM can be seen during tissue injury following a variety of insults such as those that occur in the adult respi ...
Modulation of calcium by sympathetic activation
... are present at 50 mM or higher concentrations and are dispersed widely in the cell. Relative receptor locations can also regulate this signalling cascade. For example, M2-muscarinic receptor activation can either decrease or increase concentrations of cAMP levels, depending on whether they were prod ...
... are present at 50 mM or higher concentrations and are dispersed widely in the cell. Relative receptor locations can also regulate this signalling cascade. For example, M2-muscarinic receptor activation can either decrease or increase concentrations of cAMP levels, depending on whether they were prod ...
MolCellNeuroCBl
... by stimulation of afferent fibers of LC neurons in the presence of the AMPAR blocker CNQX (193 ⫾ 30% versus 111 ⫾ 8% without D15, n ⫽ 5, P ⬍ 0.02, Fig. 1A and inset). Similar results were obtained by monitoring excitatory postsynaptic currents (not shown). In either case the developing increase of t ...
... by stimulation of afferent fibers of LC neurons in the presence of the AMPAR blocker CNQX (193 ⫾ 30% versus 111 ⫾ 8% without D15, n ⫽ 5, P ⬍ 0.02, Fig. 1A and inset). Similar results were obtained by monitoring excitatory postsynaptic currents (not shown). In either case the developing increase of t ...
Involvement of Native TRPC3 Proteins in ATP
... cyte chemoattractant protein-1 in dermal microvascular endothelium.6 In human coronary artery endothelial cells (HCAECs) ATP induces expression of VCAM-1 and monocyte adhesion through stimulation of P2Y2 receptors,7 in line with its effect in an in vivo model of neointima hyperplasia.8 This effect i ...
... cyte chemoattractant protein-1 in dermal microvascular endothelium.6 In human coronary artery endothelial cells (HCAECs) ATP induces expression of VCAM-1 and monocyte adhesion through stimulation of P2Y2 receptors,7 in line with its effect in an in vivo model of neointima hyperplasia.8 This effect i ...
FluoProbes Luciferin substrates
... Here are proven buffer systems that are known maximize performance and sensitivity: Notes: To dissolve in buffered saline start by using the predicted molar alkalinity using Sodium Hydroxide (NaOH) added to the buffer before adding d-Luciferin. If a precipitate forms adjust the pH higher until the s ...
... Here are proven buffer systems that are known maximize performance and sensitivity: Notes: To dissolve in buffered saline start by using the predicted molar alkalinity using Sodium Hydroxide (NaOH) added to the buffer before adding d-Luciferin. If a precipitate forms adjust the pH higher until the s ...
Analgetika kuat, Schunack
... It controls a wide range of biological functions ranging from nociception to food intake, from memory processes to cardiovascular and renal functions, from spontaneous locomotor activity to gastrointestinal motility, from anxiety to the control of neurotransmitter release at peripheral and central s ...
... It controls a wide range of biological functions ranging from nociception to food intake, from memory processes to cardiovascular and renal functions, from spontaneous locomotor activity to gastrointestinal motility, from anxiety to the control of neurotransmitter release at peripheral and central s ...
pdf file - John Innes Centre
... Downloaded from www.jbc.org at JOHN INNES CENTRE LIBRARY, on October 22, 2010 ...
... Downloaded from www.jbc.org at JOHN INNES CENTRE LIBRARY, on October 22, 2010 ...
The Primary Sensations of Smell
... first diffuses into the mucus that covers the cilia. Then it binds with receptor proteins in the membrane of each cilium it is coupled with Gprotein, immediately activates adenylyl cyclase, which converts adenosine triphosphate(ATP) into cyclic adenosine monophosphate (cAMP). Finally, this cAMP open ...
... first diffuses into the mucus that covers the cilia. Then it binds with receptor proteins in the membrane of each cilium it is coupled with Gprotein, immediately activates adenylyl cyclase, which converts adenosine triphosphate(ATP) into cyclic adenosine monophosphate (cAMP). Finally, this cAMP open ...
Wnt signaling
... Canonical pathway • In developing thymocytes or in thymic epithelium • Signals from the Wnt-Fz-LRP6 complex lead to the phosphorylation of three domains of Dishevelled (Dvl), a family of cytosolic signal transducer molecules. • Activation of Dvl ultimately leads to phosphorylation and consequently i ...
... Canonical pathway • In developing thymocytes or in thymic epithelium • Signals from the Wnt-Fz-LRP6 complex lead to the phosphorylation of three domains of Dishevelled (Dvl), a family of cytosolic signal transducer molecules. • Activation of Dvl ultimately leads to phosphorylation and consequently i ...
Nitrogen Assimilation
... • Properties of Glutamine Synthetase • Regulation of Glutamine Synthetase • Glutamine as a major nitrogen donor ...
... • Properties of Glutamine Synthetase • Regulation of Glutamine Synthetase • Glutamine as a major nitrogen donor ...
Receptors as Drug Targets
... Design of agonists •Agonists mimic the natural messenger of a receptor • Agonists bind reversibly to the binding site and produce the same induced fit as the natural messenger - receptor is activated • Similar intermolecular bonds formed as with natural messenger • Agonists are often similar in str ...
... Design of agonists •Agonists mimic the natural messenger of a receptor • Agonists bind reversibly to the binding site and produce the same induced fit as the natural messenger - receptor is activated • Similar intermolecular bonds formed as with natural messenger • Agonists are often similar in str ...
Functions and Mechanisms of Fibroblast Growth Factor (FGF
... system is the respiratory organ of insects and is formed as a multicellular, branched tubular network. It develops by sequential sprouting of primary, secondary, and terminal branches from an epithelial sac of ~80 cells in each body segment of the embryo (Figure 1D) [32]. First, six tracheal buds fo ...
... system is the respiratory organ of insects and is formed as a multicellular, branched tubular network. It develops by sequential sprouting of primary, secondary, and terminal branches from an epithelial sac of ~80 cells in each body segment of the embryo (Figure 1D) [32]. First, six tracheal buds fo ...
General principles of cellular communication
... receptors (names that variously identify a key component, signal, receptor type or function). These seven pathways are used during development to define the size, shape and other characteristics of an animal. How can so few pathways achieve so much? The answer is that signalling pathways can act tog ...
... receptors (names that variously identify a key component, signal, receptor type or function). These seven pathways are used during development to define the size, shape and other characteristics of an animal. How can so few pathways achieve so much? The answer is that signalling pathways can act tog ...
Review Article GPCRs: Lipid-Dependent Membrane Receptors That
... five main families, named Glutamate, Rhodopsin, Adhesion, Frizzled, and Secretin according to the GRAFS classification [7, 8]. Each of these families is characterized by long evolutionary history. Cellular signaling by GPCRs involves their activation by ligands present in the extracellular environme ...
... five main families, named Glutamate, Rhodopsin, Adhesion, Frizzled, and Secretin according to the GRAFS classification [7, 8]. Each of these families is characterized by long evolutionary history. Cellular signaling by GPCRs involves their activation by ligands present in the extracellular environme ...
Purinergic signalling
Purinergic signalling (or signaling: see American and British English differences) is a form of extracellular signalling mediated by purine nucleotides and nucleosides such as adenosine and ATP. It involves the activation of purinergic receptors in the cell and/or in nearby cells, thereby regulating cellular functions.The purinergic signalling complex of a cell is sometimes referred to as the “purinome”.