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المملكة العربية السعودية وزارة التعليم العالي جامعة سلمان بن عبدالعزيز كلية العلوم الطبية التطبيقية وادي الدواسر Kingdom of Saudi Arabia Ministry of Higher Education Salman Bin Abdulaziz University College of Applied Medical Science Wadi Addawasir Medical Lab Sciences Department First Midterm Exam nd 2 Semester, Level-5, 1433/1434 H Student name: ...................................... Student number: ................................. Day/Date: Saturday, 04/05/1434 H Course Title: Clinical chemistry-I Course code and number: MLAB-353 Section-47 Total marks: 30 Time: 2 hours ____________________________________________________________________________________________ Student marks Section No. Marks 1 2 3 4 5 10 6 ______ Total 30 Name of teacher Corrected by Signature Dr. Kakul Husain Reviewed by 1 Dr. Kakul Husain المملكة العربية السعودية وزارة التعليم العالي جامعة سلمان بن عبدالعزيز كلية العلوم الطبية التطبيقية وادي الدواسر Kingdom of Saudi Arabia Ministry of Higher Education Salman Bin Abdulaziz University College of Applied Medical Science Wadi Addawasir Medical Lab Sciences Department First Midterm Exam nd 2 Semester, Level-5, 1433/1434 H Student Name: ...................................... Day/Date: Saturday, 04/05/1434 H Course Title: Clinical Chemistry-I Student Number: ................................. Time: 2 hours ______________________________________________________________________________________ Please answer all the following questions: [1] Choose the correct answer:- [10X½= 5 Marks] 1. Epinehrine is produced in the ................... …………… a. beta-cells b. alpha-cells c. adrenal cortex d. adrenal medulla 2. Actin and myosin are the examples of …………………… proteins. a. contractile b. structural c. storage d. transport 3. Which one of the following represents the following reaction………………… a. catabolism b. polarization c. rotation d. mutarotation 4. The amino acids are converted in the body to ……………………. a. proteins b. carbohydrates c. fats 2 Dr. Kakul Husain d. none of the above 5. ………………………..are specialized proteins involved in defending the body from antigens. a. Enzymes b. Antibodies c. Transport proteins d. Structural proteins 6. The process called …………..………is the first source utilized as the fat deposits within the body. a. b. c. d. gluconeogenesis hydrolysis lipolysis glycogenesis 7. Amino acids that cannot be synthesized by our body are known as……………….. a. acidic amino acids b. basic amino acids c. non-essential amino acids d. essential amino acids 8. …………... is a compound lipid. a. fatty acid b. oils c. waxes d. phospholipids 9. Each triplet of nucleotides, called a codon, specifies ……….… amino acid. a. one b. two c. three d. none 10. Which one of the following is a complex protein…………………………. a. lipoproteins b. phospho-proteins c. glycoproteins 3 Dr. Kakul Husain d. all if the above [2] Fill in the blanks from the following table: sucrose bi-functional [10X½=5 Marks] lipids hormone genetic purine albumin diabetes maltose starch waxes 1) Lipids are a diverse group of natural fatlike compounds found in both plants and animals. 2) The disease associated with hyperglycemia is called diabetes mellitus. 3) Waxes are esters of fatty acids with long chain monohydric alcohols. 4) Polysaccharides are hydrolysed to the disaccharide maltose by the enzyme amylase. 5) Amino acids are bi-functional compounds containing both a carboxylic acid group and a basic amino group. 6) All monosaccharaides and the disaccharides other than sucrose are reducing sugars. 7) The three fractions of protein in the plasma are called albumin, globulin, and fibrinogen. 8) Proteins tend to have a complex three dimensional structure. 9) Hormonal proteins are messenger proteins which help to coordinate certain bodily activities. 10) Each protein species contains one or several polypeptide chains of defined amino acid sequence. [3] Put true ‘T’ or false ‘F’ for the following statements: - [10X½= 5 Marks] 4 Dr. Kakul Husain F 1) is a basic amino acid. T 2) Insulin overdose in treatment of diabetes is probably the most common cause of hypoglycemia. F 3) Glucagon is secreted by the beta cells of the pancreas. F 4) About 23 amino acids are essential. F 5) The pH of the stomach is between 5 and 7. 6) Phospholipids are the main constituents of cell wall. F T 7) A monosaccharide containing 6 carbon atoms is known as a hexose. F 8) Beeswax is valued for its toughness and water resistance. T 9) Keratins strengthen protective coverings such as hair, quills, feathers, horns and beak. T 10) Waxes are the esters of fatty acids and long chain alcohols other than glycerol. 5 Dr. Kakul Husain [4]. Write short notes on any two [02] of the followings:- [2X2½ =5 Marks] Two functions of amino acids in human body: 1) The amino acid may be converted into body protein. 2) Oxidation may take place to provide energy. Insulin: Insulin is a hormone produced in the beta-cells of the pancreatic islets of Langerhans. Antibodies: Antibodies are specialized proteins involved in defending the body from antigens. Two functions of lipids are:1. They serve as intracellular fuel reserves. 2. They are a transport form of metabolic fuel. 3. They are structural component of cell membranes. [5]. Write the names of the labelled part of the diagram: [1X5 =5 Marks] (a) . Primary structure (b) . Secondary structure – pleated sheets 6 Dr. Kakul Husain (c) . Secondary structure-α-helix (d) . Tertiary structure (e) . Quaternary structure 7 Dr. Kakul Husain