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Pharmaceutics I First question: Chose the correct answer: 1- Pharmacy is defined as: (A) Art of preparing of drugs (B) Art of dispensing of drugs (C) Place where drugs are sold (D) All the above (30 marks) 2- Synthetic drugs are preferred because they: (A) Overcome the problem of product safety (B) To avoid inappropriate sources (such as urine) (C) To avoid transmission of diseases (D) All the above 3- Dosage form can be defined as: (A) Delivery system of drug molecules (B) Medicinal plants (C) Dispensing of drugs (D) Non of the above 4- At desirable effect, drug concentration is: (A) Not so high (B) Not so low (C) Very high (D) A & B 5- The local effect of drugs means that: (A) The drug is absorbed to the blood (B) The drug is partially absorbed to blood (C) The drug is not absorbed to blood (D) All the above 6- Local effect can be obtained when the drug is applied to: (A) (B) (C) (D) Skin Eye Vagina All the above 7- Advantages of oral route are: (A) Self administration of drugs (B) Effective for most drugs (C) Can be used for operative patients (D) A & B 8- Oral route is not suitable for patients with: (A) Vomiting (B) Malabsorption states (C) Pre-operative patients (D) All the above 9- The buccal route has the following advantages except: (A) Can be used in unconscious patient (B) Drug absorption is low (C) Avoid drug inactivation by the liver (D) Drug absorption is rapid 10- The inhalation route has the following properties: (A) High blood flow (B) High surface of the alveolar membrane (C) Rapid drug absorption (D) All the above 11- Transdermal route of drug administration depends on: (A) Skin (B) Rectum (C) Lung (D) Brain 12- Parenteral routes include: Page (2) of (7) (A) (B) (C) (D) IV IM SC All the above 13- The oral route can be used for: (A) Local effect (B) Systemic effect (C) A & B (D) Non of the above 14- Topical route include the following: (A) Nasal route (B) Eye route (C) Vaginal route (D) All the above 15- Solid dosage forms include the following: (A) Granules (B) Suppositories (C) Lozenges (D) All the above 16- Capsules should be: (A) Chew (B) Swallow whole (C) Be given intravenous (D) Non of the above 17- Dusting powder is used: (A) Internally (B) Externally (C) By intravenous route (D) All the above 18- Suppositories are given by: Page (3) of (7) (A) (B) (C) (D) Mouth Vagina Rectum B&C 19- Liquid dosage forms include: (A) Solutions (B) Syrups (C) Lotions (D) All the above 20- Liquid dosage forms include the following except: (A) Enemas (B) Tablets (C) Solutions (D) Syrups 21- Syrups have the following properties: (A) Concentrated aqueous solution of sucrose (B) Can be used to mask undesirable effect of some drugs (C) Prolonged use encourage dental decay (D) All the above 22- Which sugar is used in syrup preparation: (A) Glycogen (B) Mannitol (C) Sucrose (D) Non of the above 23- Drops can be instilled into: (A) Eye (B) Nose (C) Ear (D) All the above 24- Gargles & mouth wash can be used for: Page (4) of (7) (A) (B) (C) (D) Prevent throat infection Treat throat infection Treat headache A&B 25- Semi-solid dosage forms include: (A) Creams (B) Ointments (C) Gels (D) All the above 26- Aqueous creams are: (A) Greasy (B) Not greasy (C) Solid preparations (D) Non of the above 27- Gels have the following properties: (A) Translucent preparations (B) Non greasy preparations (C) Semi-solid preparations (D) All the above 28- The origin of the word (pharmacy) is: (A) Pharmakon (B) Hospital (C) Drug (D) Non of the above 29- The term percentage means: (A) By hundred (B) Rate per hundred (C) Rate per ninety (D) A & B 30- The term (% W/W) means: Page (5) of (7) (A) Number of grams of solute in 50 grams of mixture (B) Number of grams of solute in 60 grams of mixture (C) Number of grams of solute in 80 grams of mixture (D) Number of grams of solute in 100 grams of mixture ***************************************************************** Second question: Put (T) for true sentence and (F) for false one.(10 marks) 1- PPM calculations are used for dilute solutions. (T) 2- Metric system is used in pharmaceutical calculations. (T) 3- Liter is the unit of volume in the apothecary system. (F) 4- 1 gram is equal 10 kilogram. (F) 5- The date of prescription is written by the nurse. (F) 6- The inscription contains the doctor address. (F) 7- Prescription is an order of medication issued by the physician. (F) 8- Signature contains name & address of the patient. (F) 9- The abbreviation (Lot.) means capsules. (F) 10- Compound prescription do not require mixing of ingredients. (F) ***************************************************************** Third question: Complete the following sentences:(10 marks) 1- Generic name prescription is written by the generic name of the drug. 2- Acne vulgaris can be abbreviated as A. V. 3- Stabilizer is the substance that protect formulation from degradation. 4- Solutions may be used internally & externally. 5- Solvent (vehicle) is the medium in which ingredients are dissolved Page (6) of (7) 6- Drugs in solution are less stable than in solid dosage forms. 7- The finer the powder, the rapid or high dissolution. 8- On rising temperature, most chemicals exhibit higher solubility. 9- Polar drugs can be easily dissolved in polar solvents. 10- Liquid preparations prepared by extraction are called extracts. ***************************************************************** Fourth question:Give theme dical terms of the following: (5 marks) 1-Liquid preparations used externally & applied to unbroken skin. (Lotions or liniments) 2-Substance that (Preservative) prevent microbial contamination of solutions. Page (7) of (7)