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]ً[اكتب نصا Anti-D Prince Mohammed Bin Fahd University Giving Anti-D injections Duaa Abd Alrsool Alhamzah March2, 2013 1 ]ً[اكتب نصا Anti-D INDEX Introduction. 3 Definition. 4 What happens? + When you will be given Anti-D. 5 How is Anti-d given? + Possible side effects. 6 Conclusion 7 References 8 2 ]ً[اكتب نصا Anti-D Introduction: As you know there are four main blood types which are (A, B, AB and O). And these blood groups included RH factor. 85% of us have this factor and Rh positive. In the other hand, 15% need the factor and are Rh negative. One of the Rh factors called Rh – D is especially important. This research will give you information about Rh-D and the need for some mothers to have Rh-D which in general called ( Anti-D) injections to safeguard their babies. 3 ]ً[اكتب نصا Anti-D Definition: Anti-D or immunoglobulin is an ingredient of donated blood from people who have developed antibodies against 'positive blood'. The use of 'anti-D' has greatly reduced the happening of Rhesus hemolytic disease for babies by reducing the chances of a woman forming antibodies from about 10%to 20% to about 0.2 to 1.5%. 4 ]ً[اكتب نصا Anti-D Giving Anti-D injections Rh-negative women can't safeguard her baby. Did you know why? If a mother who has developed the antibodies has another Rh positive baby, her antibodies will cross the placenta and may damage the baby’s red blood cells. However, untreated babies may be anaemic have a risk of brain damage or even die before birth.Dr.Tom/ said "The use of anti-d is to “fool” your body’s immune system into thinking that it already has immunity to rhesus positive blood. Therefore, if it comes into contact with rhesus positive blood it automatically thinks it has the antibody and doesn’t make any more.The antid injection “fades” away over the next 3 months, leaving your body without any anti-d antibodies"( http://www.thanksdoctor.co.uk) (Surgery and Anti, 2009). The mainly reasons for giving Anti-D injections. When you take pregnancy test and you may have some of symptoms or cases such as have any vaginal bleeding during your pregnancy, have an abortion or terminate your pregnancy, and have a medical procedure such as an amniocentesis In some cases a blood sample may be taken prior to receiving ANTI-D. "The Rh factor is protein present on the surface red blood cells.Rh disease is a state in which woman with Rh-negative blood group is exposed to Rh-positive leading to the formation of called Rh antibodies"Dr.Shirish Kumar said (http://doctor.ndtv.com). Dr,Chrissie Hammonds said "When you gave birth to your last baby your midwife will have taken a sample of blood from your baby's umbilical cord to check if your baby was rhesus-positive (RhD-positive) or rhesus-negative (RhD-negative). If your baby was RhD-positive you will 5 ]ً[اكتب نصا Anti-D have been recommended to have the anti-D injection. The anti-D injection is only necessary for RhD-negative mothers with RhD-positive babies as there is a slight risk that their blood might mix and cause the mother to form antibodies. The antibodies can cause complications for subsequent Rh-D positive babies.( http://www.babycenter.com.au) (Anti-d, 2009). There are many ways to talk the Anti. Anti-D is given as an injection, usually into a muscle in your leg or arm. For some people with bleeding problems, the injection may need to be given under the skin. You might feel pain or stiff where the injection was given. This will Disappears in few hours.Sometims you will get high temperature and this is rare , also you will recover quickly. Everyone's reaction to a medicine is different. It is difficult to predict which side-effects you will have from taking a particular medicine. The important thing is to tell your doctors if you are having problems with your medicine. The result of these side-effects is unknown. For instance, chills, faster heart rate, fever, headaches, vomiting, skin problems,nausea,lowered blood pressure and injection site problems such as pain or tendemess. Furthermore, Anti-d will not affect your baby. Finally , 40 years ago Scientists invent this Anti-d injection. The objective of this invention to avoid pregnancy woman who has Rh- negative blood. Conclusion Anti-D is made from blood plasma (the fluid part of the blood). The blood was 6 ]ً[اكتب نصا Anti-D donated to the Australian Red Cross Blood Service by volunteer donors. To make sure infectious diseases cannot be transmitted by Anti-D injections, every blood donation used to make Anti-D is tested for blood diseases like hepatitis and HIV.To ensure the safety of the blood, the Red Cross also has very strict controls on blood donors. No product made from human blood plasma can be guaranteed 100 per cent free of infectious diseases. However, Anti-D has been used in Australia for more than30 years, and no an Anti-D injection and so far no statistics prove that it's not safe to the patient but as precaution always talk to the doctor to check your situation that it may be against the Anti-D injection use. The Anti-D injection used in Australia is manufactured by CSL Limited. Rebecca (patient member of mumz world site) said "There ae times in all pregnancies where blood from the mother and the baby may mix. This occasionally happens for no reson or it might be caused by small pacental bleed (occurring after 12 weeks of pregnancy). If both other and baby have the same rhesus status, i.e. they are both RhD-positive or both RhD-negative, this causes no problem. However if an RhD-negative mother is carrying a RhD-positive baby, your immune system may react to the baby's blood as if it were a "foreign invader" and produce antibodies against it (http://www.netmums.com) (Anti-d, 2009). 7 ]ً[اكتب نصا Anti-D REFERECE: Australia pregrency team doctors: http://www.birth.com.au/Blood-groups-and-impact-on-pregnancy/Giving-AntiD-injections National health and medical research council: http://www.nhmrc.gov.au NGH Organization: .http://www.nhs.uk/medicine-guides Essentials of Obstetrics and gynecology book (Fifth Edition ) ( http://www.thanksdoctor.co.uk). ))http://doctor.ndtv.com ( http://www.babycenter.com.au). 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