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Cell Cycle and Cancer Test Review Sheet NAME _________________________ 1) What are three reasons why cells divide? 2) Why are cells so small . 3) Which organelle plays a vital role during cell division?_________ 4) If the parent cell contains 46 chromosomes and the daughter cells contain chromosome. 5) What are the four phases of mitosis? 6) During which phase of the cell cycle is DNA duplicated? 7) Why is it important that a cell’s DNA is duplicated before cell division? The 8) Which phase of the cell cycle does the cell spend the longest time 9) What is the role of spindle fibers during cell division? 10) 11) Write a brief explanation of each phase Interphase Prophase Metaphase Anaphase Telophase Cytokinesis 12) Provide a brief explanation of each term Spindle Fibers- Centromere- 13) Cancer What is cancer? What happens in the cell that leads to cancer? What are three common treatments for Cancer? Cell Cycle and Cancer Test Review Sheet KEY NAME _________________________ 1) What are three reasons why cells divide? a. to repair tissue b. to grow and develop while keeping cells small c. reproduction 2) Why are cells so small Surface area to volume ratio Large ratio is desired (Ex: 1,000,000/1) because lots of surface area help materials get into and out of the cell QUICKLY and little volume is desired because it slows down the movement of these materials. 3) Which organelle plays a vital role during cell division? Nucleus 4) If the parent cell contains 46 chromosomes and the daughter cells contain 46 chromosome. 5) What are the four phases of mitosis? a. Prophase b. Metaphase c. Anaphase d. Telophase 6) During which phase of the cell cycle is DNA duplicated? S Phase 7) Why is it important that a cell’s DNA is duplicated before cell division? The DNA needs to be duplicated before the cell divides SO THAT both new cells have the SAME AMOUNT of DNA. 8) Which phase of the cell cycle does the cell spend the longest time? Interphase (90% of the time) 9) What is the role of spindle fibers during cell division? To move the chromosomes evenly between the two new cells 10) A PROPHASE B METAPHASE C ANAPHASE D TELOPHASE/ BEGINNING CYTOKINESIS E INTERPHASE 1 CENTRIOLE 2 SPINDLE FIBER 3 SISTER CHROMATID 4 DAUGHTER CELLS 5 CHROMATIN (DNA) 6 CELL MEMBRANE 7 NUCLEOLUS 8 CENTRIOLES 9 CHROMOSOME 10 NUCLEUS 11) Write a brief explanation of each phase Interphase G1 cell size doubles, organelles double S Prophase DNA is doubled “synthesized” G2 Cell grows and prepares to divide Chromosomes condense and nucleus disappears- “PASTA” Metaphase Chromosomes move into the equator of the cell “MIDDLE” Anaphase Chromosomes are pulled away towards opposite poles of the cell “AWAY” Telophase Nuclear membranes reappear in both poles, chromosomes unwind, starts to show 2 cells “TWO” Cytokinesis Cytoplasm divides in 2 Plants- cell plate Animals- cleavage furrow 12) Provide a brief explanation of each term Spindle Fibers- fibers that attach to every chromosome and assist to move them away towards opposite ends of the cell Centromere- the middle part of chromosomes that attaches the two sister chromatids together 13) Cancer What is cancer? The uncontrollable division of cells What happens in the cell that leads to cancer? There must be a change in the DNA (mutation) that causes the cell to lose control of its cell cycle and constantly divide What are three common treatments for Cancer? a. Chemotherapy- used to treat cancers located in several parts of the body, KILLS THE FASTEST DIVIDING CELLS which includes hair cells and the cells that line the intestine, causing the sick feeling and hair to fall out b. Radiation- TARGETED therapy, useful only when the cancer is found in ONE area. Uses energy waves to DAMAGE DNA in cancer cells, but can also damage DNA in healthy cells, causing the symptoms. c. Surgery- removes the tumor and often healthy tissue. Helpful only if the tumor is found in one location, often used with some radiation or chemotherapy.