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Major Cancer
Milestones
Major Cancer Milestones
1970–1979
Major Cancer Milestones
1970–1979
Early 1970s: Increased use of radioactive ''seeds''
to target prostate and other cancers
Major Cancer Milestones
1970–1979
Late 1960s–early 1970s: Screening tests for
colorectal cancer dramatically reduce deaths
1971: National Cancer Act of 1971 becomes law
1971: More limited mastectomy proven effective for
early-stage breast cancer
Major Cancer Milestones
1970–1979
1970s: CT scanning provides clearer images of
tumors, guiding radiation and other treatments
Major Cancer Milestones
1970–1979
1970s: Use of cancer-causing asbestos declines
1975–1976: First adjuvant chemotherapy increases
cure rates for early-stage breast cancer
Major Cancer Milestones
1970–1979
1977: New treatments cure men with testicular
cancer
1977: Many women with breast cancer can opt for
breast-conserving surgery
Late 1970s: Growing use of mammography saves
lives
Major Cancer Milestones
1980–1989
Major Cancer Milestones
1980–1989
1981: First cancer vaccine prevents cancercausing hepatitis B infection
Major Cancer Milestones
1980–1989
1982: Limited surgery helps rectal cancer patients
avoid colostomies
Major Cancer Milestones
1980–1989
1986: PSA test enables early detection of prostate
cancer
1986: Second-hand smoke formally declared a
carcinogen
1986: Tamoxifen reduces breast cancer recurrence
1986: Global guidelines help ensure proper pain
management
Major Cancer Milestones
1980–1989
1985–1991: Adjuvant therapy proven for colorectal
cancer
Late 1980s: Benzene discovered to cause blood
cancers
Major Cancer Milestones
1980–1989
1989: Drugs to boost blood cells help patients
finish cancer treatment, reduce infections
Major Cancer Milestones
1990–1999
Major Cancer Milestones
1990–1999
Early 1990s: Laparoscopic surgery minimizes pain,
recovery time for several cancers
Early 1990s: Shift to 3-D radiation treatment plans
increases precision, safety of therapy
Major Cancer Milestones
1990–1999
Early 1990s: Cancer deaths begin steady decline
1991: Powerful anti-nausea drugs alleviate major
side effect of cancer treatment
Major Cancer Milestones
1990–1999
1992: Sentinel lymph node biopsy determines
cancer's spread with fewer side effects
Major Cancer Milestones
1990–1999
1970s–1990s: Melanoma linked to sun exposure
1992–1994: Taxanes emerge as a vital
chemotherapy option for ovarian, breast cancer
Major Cancer Milestones
1990–1999
1997: FDA approves first-ever targeted cancer
drug, rituximab
1997: Surgery found to cure some patients with
advanced colon cancer
Late 1990s: Prophylactic surgery helps prevent
breast and ovarian cancers in women at high risk
Major Cancer Milestones
1990–1999
Late 1990s: New radiotherapy technique enables
precise targeting of tumors near sensitive tissue
1998: Drug therapy can reduce breast cancer risk
in women at high risk
1998: Treatment guidelines highlight obesitycancer link
1998: Chemotherapy before surgery helps more
women benefit from breast-conserving treatment
Major Cancer Milestones
1990–1999
1998, 2006: First targeted anti-breast cancer drug,
trastuzumab (Herceptin), has major impact on care
Major Cancer Milestones
2000–Present
Major Cancer Milestones
2000–Present
2000: Study links household radon exposure to
lung cancer
Major Cancer Milestones
2000–Present
2001: New targeted therapy transforms treatment
for rare leukemia
2001: Imatinib found highly effective against rare
gastrointestinal tumor
Major Cancer Milestones
2000–Present
1998–2003: Doubling of U.S. biomedical research
budget expands cancer research
Major Cancer Milestones
2000–Present
2003: Scientists decode the human genome
2003: Obesity pinpointed as cause of many cancer
deaths
2003, 2004: First targeted drugs for lung cancer
attack ''EGFR'' receptor
Major Cancer Milestones
2000–Present
2004: FDA approves first ''anti-angiogenic'' drug,
bevacizumab
2004, 2006: Two targeted drugs approved for
advanced colon cancer
2004–2005: Adjuvant therapy proven effective in
lung cancer
Major Cancer Milestones
2000–Present
2005: U.S. launches effort to map cancer genomes
2005: Research sheds light on long-term health
problems of cancer survivors
Major Cancer Milestones
2000–Present
2006: First vaccine approved to prevent cervical
cancer
Major Cancer Milestones
2000–Present
2009, 2010: Major studies report conflicting results
about benefits of PSA testing
Major Cancer Milestones
2000–Present
2010: CT scanning reduces lung cancer deaths
among heavy smokers
2010: First drug shown to improve survival for
patients with advanced melanoma
2010: Adding palliative care to standard
chemotherapy improves survival for advanced lung
cancer patients
2011: Record number of Americans surviving
cancer – nearly 12 million
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% of Patients Surviving Five Years
Major Cancer Milestones
Five-Year Survival
70
65
60
55
50
45
Year of Diagnosis
Source: National Cancer Institute
Major Cancer Milestones
Mortality
Cancer Deaths per 100,000 People
225
215
205
195
185
175
Year of Death
Source: National Cancer Institute
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00
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09
New Cancer Cases per 100,000 People
Major Cancer Milestones
New Cases
524
504
484
464
444
424
404
384
364
Year of Diagnosis
Source: National Cancer Institute
Visit CancerProgress.Net for an interactive timeline of progress
against a range of common cancers
CancerProgress.Net is a project of the American Society of
Clinical Oncology, which represents nearly 30,000 physicians
who treat people with cancer and research new cures