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Scientific Meeting British Geriatrics Society, SE Thames Region 15 September 2005 Host: University Hospital Lewisham, Lewisham High Street, SE13 6LH Present: Dr R Lewis (Chairman) Dr A Abdulla (Hon Secretary) Dr K Rhodes Dr J Potter Dr M Patel Dr W Hildick-Smith Dr B Bora Dr K Dey Dr N Aftab Dr W Fitzpatrick Dr R Rangasamy Dr C Thom Dr K Rudra Dr K Singhal Dr P Brighton Dr D Mukhopadhyay Dr N Hayes Dr F Martin Dr S Jones Dr S Panagiotakis Dr A Van Heuven Dr P Tsang Dr J Burch Dr S Roe Dr R Pathansali Dr J Dennison Dr Smithard Dr J Evans Dr B Al-Saffar Dr Roger Lewis, the Chairman, commenced the meeting after welcoming all attendants, with a programme of five presentations four of which were of interesting clinical cases and one was an audit on Admissions to King’s College Hospital from surrounding Care Homes. The presentations were: 1) Myasthenia Gravis – A Rare Presentation with Tongue Atrophy and Fasciculation – Dr Jessica Burch and Dr M Patel, Lewisham Hospital 2) Neuroleptic Malignant Like Syndrome without Rigidity in a Patient with Parkinson’s Disease – Dr Nawaid Ahmad and Dr Belinda Kessel, Princess Royal University Hospital 3) CPR Preference of Older In-patients: A Case Controlled Study – Dr D Mukhopadhyay and Dr F Martin, St Thomas’/Guy’s Hospital 4) Intravenous Pamidronate for Intractable Metastatic Bone Pain – Dr K Conway and Dr A Abdulla, Princess Royal University Hospital 5) Audit of admissions of Care Home residents in Hospital – Nicky Hayes, King’s College Hospital The abstracts for these presentations are attached and a summary of the PowerPoint presentations are available from the secretary, Dr A Abdulla. After a short coffee break, the meeting reconvened for its second half and commenced with a lecture by Dr Daya Gunawardena on “The Role of Geriatricians in the management of dementia”. This was followed by an update on Parkinson’s Disease by Dr K Chaudhari, Consultant Neurologist at UHL & KCH. A good amount of discussion followed each of the lectures and the meeting as a whole was well attended. It was agreed that Dr Jessica Burch, SpR at Lewisham Hospital, be awarded the SpR presentation prize for the best presentation. ABSTRACT (1) Ref: BGS.call for papers July 2005 BRITISH GERIATRICS SOCIETY MEETING 15 September, 2005 University Hospital Lewisham Lewisham High Street, London SE13 6LH Name DR JESSICA BURCH Address UNIVERSITY HOSPITAL LEWISHAM, LEWISHAM HIGH ST, LONDON Tel.No. BLEEP 552 / 07870 650052 I feel this is a very interesting case which has a number of learning points with regards to the diagnosis and more specifically to the course and treatment of this patients illness. CASE REPORT Myasthenia Gravis – A Rare Presentation with Tongue Atrophy and Fasciculation Dr J Burch, Dr M Patel A 76 year old man presented with a three week history of progressive dysarthria and dysphagia, describing extended mastication with difficulty in food bolus manipulation. He had evidence of tongue atrophy and fasciculation. In the absence of any other clinical features, the differential included amytrophic lateral sclerosis and paraneoplastic disease. After a number of tests and a significant deterioration, it was noted that his acetylcholine receptor antibodies were elevated. He was transferred to Kings Hospital for further confirmatory tests. His disease was unusually aggressive in its course with multiple complications related to the disease as well as its treatment. Bulbar presenations are recognised in myasthenia, but tongue atrophy is rare and usually late in the disease. We found no previous published cases of fasciculation. Myasthenia needs to be considered, even in the absence of classical symptoms and in all age groups, in order to be diagnosed early and treated appropriately. ABSTRACT (2) Neuroleptic malignant like syndrome without rigidity in a patient with Parkinson’s disease Dr. Nawaid Ahmad, Dr. Belinda Kessel, Princess Royal University Hospital, Farnborough, Kent, UK ABSTRACT Objective: To describe a case of Neuroleptic Malignant Syndrome without rigidity, due to withdrawal of anti-parkinsonian medications, in a patient with Parkinson’s disease. Case: A 72 year old male with 12 year history of Parkinson’s disease on maintenance treatment (Sinemet Plus 1tab/2hrly, Sinemet CR 1 tab. nocte, apomorphine pump, Amantadine 100mg BD, cabergoline 4mg BD and Madopar dispersible prn ), was admitted to hospital with inability to eat and drink and dyskinesia. On admission he was found to be very dyskinetic and this made his swallowing ability very poor. He was able to swallow only thin fluids. As his swallowing was considered to be unsafe he did not receive his regular medications for forty eight hours. Also during this time he had an Endoscopy which meant being nil by mouth and missing the regular doses of his drugs. On the fourth day of admission he developed symptoms of Neuroleptic malignant syndrome and became confused, febrile (38 degrees), hypotensive (BP: 40/20) with high CK levels (9381 IU/l) associated with further derangement of renal function and metabolic acidosis. However he did not develop any rigidity, instead he was found to be still very dyskinetic. He was admitted to ITU and required intubation and ventilatory support with sedation. Soon after he was restarted on his anti-parkinsonian medications and his confusion & fever subsided, he became more alert and was successfully weaned off from the ventilator. His kidney function also continued to improve. Unfortunately he developed several complications including pneumonia, sepsis and needed haemodialysis at a tertiary hospital where he ultimately died. Conclusion: This case demonstrates that Neuroleptic malignant like syndrome can present without rigidity on withdrawal of anti-parkisonian medications. We will review the literature on NMS in association with Parkinsonism. Discussion: This case opens up an interesting discussion on how to manage NMS Parkinsonian patients with Dyskinesia. Whereas you would like to continue with the antiparkinsonian medications for NMS, dyskinesia would mean reducing or stopping any one or more of these medications. ABSTRACT (3) The use of iv pamidronate in acute intractable metastatic bone pain - Case Presentation Katie Conway, Aza Abdulla, Princess royal University Hospital A 93 year old gentleman presented to his GP with pain in his left arm and shoulder, reduced power in his left hand and episodes of his hand becoming very cold and pale – relieved by warming. He was suspected to have Raynaud’s phenomenon and thoracic outlet syndrome and imaging confirmed this. He was diagnosed to have metastatic prostate cancer which with T1 root compression. He was seen by the urology team and started hormone therapy with local radiotherapy. His primary problem became his severe inadequately controlled pain affecting his pelvis, back and arms. He was admitted for a course of pamidronate infusion over three days which had a dramatic effect on his pain, and rendered him virtually pain free for a number of weeks after which his pain relapsed slightly but was controlled on co-proxamol. Pamidronate is well recognised in the management of hypercalcaemia in malignancy, and used to reduce the number of skeletal related events in certain forms of cancer and myeloma, and in the long term management of pain in patients with bone pain secondary to metastases. There are a number of studies to support these effects. The mechanism of action is thought to be due to the potent inhibition of osteoclast-mediated bone resorption. The role of pamidronate for the acute management of metastatic bone pain is less well defined. There are reports of using pamidronate with good success in patients with acute pain secondary to osteoporotic vertebral fractures and the suggested theory is that the mechanism of action is different to that mentioned above. It may be related to the modualtion of neuropeptides such as substance P. In conclusion this case demonstrates the dramatic effect pamidronate can have in the management of acute pain secondary to bony metastases, and certainly warrants further research to see if this effect can be demonstrated in larger patient groups, via randomised blind studies. ABSTRACT (4) BRITISH GERIATRICS SOCIETY MEETING 15 September, 2005 University Hospital Lewisham Lewisham High Street, London SE13 6LH Name_______Nicky Hayes________________________________________________________ Address Medical Care Group, 4th Floor, Hambledon Wing, Kings College Hospital, Denmark Hill London SE5 9RS______________________________________________________________ Tel.No.____020 7346 6056________________________________________________________________ Summary of your paper in no more than 200 words Audit of admissions of care homes residents to hospital The hospital admissions of residents of care homes in Lambeth, Southwark and Lewisham were audited for the period October – December 2004. Data were collected at GSTT and KCH for all admissions during this period. Limited comparison is possible with data collected from a previous period at UHL. Key findings included: The number of admissions per month is probably about 50 per hospital, the majority being from care homes with nursing (nursing rather than residential homes). In most cases the decision to admit was made by care home staff without involving GPs. The commonest diagnoses were related to infection, particularly chest and urine. Care home residents have the same average length of stay as general medical patients Underlying factors are not well recorded on EPR or discharge summaries. Dementia was recorded in 20% of cases. Mortality rates of care homes residents in hospital is up to 34% Readmission rates within 28 days from care homes are comparable with general readmission rates Implications for future service development include improvement of two-way communication between care homes and hospital, regular review of residents of care homes, which includes consideration of health care choices and end of life management planning. The role of the Care Homes Support Team in facilitating this process will be presented. ABSTRACT (5) Title: CPR preference of older in-patients: a case control study D Mukhopadhyay, F C Martin. Department of Ageing and Health, Guy’s and St Thomas’ NHS Foundation Trust ABSTRACT Method: Fifty consenting in-patients of age > 65 years with Abbreviated Mental Test Score (AMTS) > 7 were interviewed face-to-face two days pre-discharge from an urban teaching hospital about their knowledge of, preference to undergo, and estimate of survival from CPR. Data on their concurrent condition were collected from case records or with standardised assessment scales: AMTS, Barthel Index (BI), GDS-15, Cumulative Illness Rating Scale (CIRS), SF-12 Health Survey, Pre Arrest Morbidity (PAM) and Prognosis After Resuscitation (PAR) scores. Results: CPR was wanted by 72% of patients. Using logistic regression analyses there was no significant associations between preference for CPR and age (mean 82 years), gender (52% women), place of residence (86% from own/rented home), ADL-dependency (median BI 15), cognitive function (median AMTS 8), mood, general health perception, co-morbidity and predictive scores for unsuccessful CPR. Patients’ own estimate of survival chance was significantly associated with their preference for CPR (p<0.001); all 24 patients who offered an estimate of their survival chance opted for CPR, compared to 12 of 26 (46%) who did not. Conclusion: Most elderly in-patients surviving to discharge opted for CPR. CPR prognoses and multi-dimensional assessments did not predict patients’ preferences. BUSINESS MEETING MINUTES Present Dr Roger Lewis – (Chair) Dr Aza Abdulla – (Secretary) Dr Ken Rhodes Dr Finbar Martin Dr Methool Patel Dr David Black Dr James Dennison Dr David Smithard Dr W Fitzpatrick Dr Jonathon Potter, Dr S Jones, Dr R Pathansali, Dr S Panagiotakis Apologies Dr Stewart Bruce Dr Ian Sturgess Dr G Batty Dr Iain Carpenter Dr Catherine Bryant Dr Michael Jenkinson Dr M Kinirons Dr I Starke Dr M Bayliss Dr H Alexander Dr P Reynolds Dr Roger Lewis started the meeting by welcoming Dr Panagiogaiks, who was on Clinical Attachment with Dr Finbarr Martin. 1 Minutes of previous business meeting The Minutes of the last meeting held on the 17th March 05 at the Princess Royal University Hospital at Farnborough, Orpington, were approved and signed by Dr Roger Lewis 2 New members/Appointments/Awards Two recent appointments were made at Guy’s and St Thomas’s Hospital; Dr Jugdeep Dhesi appointed with particular interest in POPs surgical liaison work and Rebekcah Schiff with particular responsibility for IC work in Lambeth. Dr Adam Harper was appointed at Brighton replacing Dr H O’Neill who moved to Worthing. A Personal chair has been awarded to Ian Carpenter (University of Canterbury) 3 4 Matters Arising (a) Appointment of Father Figures: Dr Roger Lewis commented that SE Thames Region was the first Region to appoint 2 Father Figures and that both Drs Jonathon Potter and Roger Lewis have been confirmed in this post. (b) RCP report on SpR posts: Roger Lewis fed back on the report received following the College visit inspecting the SpR posts in the Region. The conclusion was that the report was complementary in general though there were some concerns mostly around achieving a balance between General Medicine and Geriatrics. The assessors have commented that in two particular centres this balance has notably shifted in favour of General Medicine and that adjustments will have to be made. There was also a comment that where the SpRs timetable is particularly busy then the individual SpR need not be present on all consultant ward rounds. It was reported that although the quality of teaching was very good, some topics, such as non medical professional teaching, were not adequately undertaken. It was also noted that the SpR attendance for the training days was not always satisfactory mainly because of the new rota and shift system and at times our training day coinciding with that of GIM. The College Committee suggested trying to direct SpRs more towards research. The Committee did comment though that our Region was doing well in this aspect as there were a number of trainees who had obtained an MD or PhD. The Committee also highlighted various areas of good practice in the Region and commented that the programme was well organised that it was well organized with a wide availability of sub-specialty training and opportunities for flexibility for staff; it also remarked on the success of the MSc course (c) Training Days/Adjustment to Trainees Curriculum Roger Lewis commented on the current training curriculum and remarked that in essence all the sub-specialties are covered each two years. He commented on the possibility of having additional competencies for subspecialties.. This view has not been supported by many of the trainees who wish to keep their options open rather than going down the narrow path of subspecialisation within geriatrics medicine as a trainee. Roger Lewis invited any other views on this subject. Finbarr Martin supported the view of the trainees and maintained that there may not be adequate time in training period to cover additional competencies. However, the trainee can use his/her own academic session to gain increased experience in an area of his/her choice. (d) Modernising Medical Careers Dr David Black, who was congratulated by Roger Lewis on his Professorship, updated the meeting on the subject of Modernising Medical Careers. He stated the intention for Trusts creating post CCST training posts which are essentially junior/sub consultant posts. He also remarked that these posts may be welcomed by some juniors. Further discussion took place around Modernising Medical Careers, the future of acute medicine and also General Medicine, and setting “knowledge exams” for trainees as well as, in the future, consultants. David Black reported that there was a lot of work that needed to be done in the near future before finalising the best way to assess compentency and a development tree for trainees/graduates. 4. BGS Regional Administration Nil to report 5 English Council Nomination Roger Lewis expressed the Region’s gratitude towards Jonathon Potter’s service on the Council of England and remarked that we had not received any nominations for replacement. Dr Mehool Patel from Lewisham was proposed by Jonathon Potter and after being seconded was voted as replacement representing the SE Thames Region. Aza Abdulla and Gwen Battie were formally appointed on the Clinical Practice and Effectiveness Committee Group on the England Council. 6 Any Other Business Nil to report. 7 Date and Time of Next Meeting 16th March 06 at Queen Mary’s Hospital, Sidcup. CME points awarded 5.5