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Chapter 10+Meiosis-Cell Growth & Division/Ch.11 iv.-Meiosis I. Cell Growth A. Limits to Cell Growth o 2 reasons cells divide rather than continuing to grow indefinitely: 1) larger a cell grows,the more demands on its _______ ➪ will not be making enough copies of DNA as size increases---This would cause an information crisis. 2) difficult to move waste and nutrients across cell ➪ rate @ which waste products leave cell depends on _______________________ of cell=total area of cell membrane ➪ rate @ which food and Oxygen are used up and waste produced depends on _____________________ ➪ RATIO OF SURFACE AREA TO VOLUMEassuming a cube shape,surface area=l x w x 6…..volume= lx w x h…. ratio = SA /volume See p.243 ➪ Volume increases faster than surface area/CAUSING RATIO TO 1 __________________..causing serious problems for cell. B. Division of Cell ➪ A cell divides into 2 daughter cells =_______________________________ ➪ This happens before a cell can get too large ➪ DNA ____________________________before cell division,solving info crisis. II. Cell Division ***simpler in prokaryotes A. chromosomes –carries genetic info in eukaryotes ➪ made up of ____________ and proteins ➪ cells of every organism have a specific # of Chromosomes ➪ humans have___ Chromosomes ➪ fruit flies have 8 ➪ usually not visible except in cell division,when they condense ➪ ________________________________ before cell division ➪ each Chromosome consists of 2 identical _________________________________, which separate from each other in cell division ➪ chromatids attached @____________________________, usually near middle B. Cell Cycle ➪ __________________________________ is in- between phase 2 ➪ ___________________________is the series of events that a cell goes through during growth and division….Where the cell grows,prepare for division,divides into 2 daughter cells ➪ 4 phases 1) M= ______________________________ ____________________ 2) S= ______________________________ ______________________________ ______________________________ __________ 3) G1 and G2= ______________________________ ______________________________ ______________________________ __________ Label diagram above-see p.245 3 C. Mitosis-4 phases ***Label ANAPHASE above ________________ 1. Prophase ➪ Longest phase ➪ Chromosomes become visible 4 ➪ _______________________,2 tiny structures near nuclear envelopeseparate and take positions on opposite ends of nucleus ➪ Centrosome region helps organize ______________________________microtubules that help separate chromosomes ➪ Chromosomes attach to __________________________ ➪ @ end chromosomes coil tightly and nuclear envelope disappears 2. Metaphase chromosomes line up @ center Centromeres go to 2 poles 3. Anaphase Centromeres split Chromatids separate and become individual _____________________ ➪ New chromosomes go to opposite poles and then stop moving 4. Telophase➪ Chromosomes disperse into tangle of material ➪ New nuclear envelopes ➪ Spindle breaks apart ➪ Nucleolus becomes visible D. Cytokinesis-divison of cytoplasm o Usually along w/ Telophase o Cell plate forms in plants that becomes the ______________________________ III. o _____________________= disorder in which some of the body’s cells lose the ability to regulate growth 5 o They do not respond to signals that regulate growth o Divide uncontrollably,making ___________________(masses of cells) o _________________=protein that regulates normal cell cycle (in eukaryotes) Chapter 11 notes-MEIOSIS ONLY IV. MEIOSIS Mendel’s principles require 2 things-1)each organism inherits a single copy for every gene from each parent. When an organism produces its own gametes,those 2 sets of genes must be separated from each other so that each gamete has only 1 set. A. Chromosome # The sets of chromosomes will be homologous,meaning that one from male corresponds w/ one from female A cell w/ both sets of homologous chromosomes is _______________,meaning 2 sets(2N)---For Drosophilia,2N=8-2 complete sets of chromosomes and 2 complete sets of genes. Gametes,however contain a __________________#-1 set of chromosomesfor Drosophilia N=4. B. Meiosis=______________________________________ ______________________________________________ ______________________________________________ ______________________________________________ ______________________________________________ ___ 2 divisions-meiosis I and Meiosis II Meiosis I – Chromosomes are replicated 1st Divide similar to mitosis,except in prophase I each chromosome pairs w/ 6 its corresponding chromosome to make a ___________________________-which has 4 chromatids They exchange portions of their chromatids in _________________________________resulting in a exchange of alleles between homologous chromosomes and produces new combinations of alleles. Homomlogous chromosomes separate and 2 new cells are formed Each cell has 4 chromatids,but they are separated Meiosis II No replication previous to M II Each chromosome has 2 chromatids 4 daughter cells contain haploid # (N) Figure 11-15 Meiosis Section 11-4 Meiosis I Go to Section: 7 Figure 11-17 Meiosis II Section 11-4 Meiosis II Prophase II Metaphase II Anaphase II Meiosis I results in two The chromosomes line up in a The sister chromatids haploid (N) daughter cells, similar way to the metaphase separate and move toward each with half the number of stage of mitosis. opposite ends of the cell. chromosomes as the original. Telophase II Meiosis II results in four haploid (N) daughter cells. Go to Section: C. Gamete Formation-In female- 1 egg cell produced and 3 _______________________________________. Male produce 4 sperm cells D. comparing Mitosis and meiosis Mitosis produces 2 genetically alike diploid cells /also allows for growth Meiosis produces 4 genetically different haploid cells/for sexual reproduction 8