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1 Diverticular Disease Elizabeth Boldon, RN, MSN Elizabeth Boldon is a Nurse Education Specialist at Mayo Clinic in Rochester, Minnesota. She received a BSN from Allen College in Waterloo, Iowa in 2002 and an MSN with a focus in education from the University of Phoenix in 2008. She has bedside nursing experience in medical neurology and the neuroscience ICU. Abstract Diverticular disease is a common disease associated with significant potential complications. Colonoscopy, X-rays and possibly computed tomography (CT) assist in the diagnosis of diverticulosis and potential complications. Initial therapy and treatment of complications, such as infection and bleeding, related to diverticulosis are discussed, which includes endoscopic and surgical interventions. nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 2 Continuing Nursing Education Course Planners William A. Cook, PhD, Director, Douglas Lawrence, MA, Webmaster, Susan DePasquale, MSN, FPMHNP-BC, Lead Nurse Planner Policy Statement This activity has been planned and implemented in accordance with the policies of NurseCe4Less.com and the continuing nursing education requirements of the American Nurses Credentialing Center's Commission on Accreditation for registered nurses. It is the policy of NurseCe4Less.com to ensure objectivity, transparency, and best practice in clinical education for all continuing nursing education (CNE) activities. Continuing Education Credit Designation This educational activity is credited for 2 hours. Nurses may only claim credit commensurate with the credit awarded for completion of this course activity. Statement of Learning Need Clinicians need to be able to recognize the symptoms of diverticular disease. Patients with diverticular disease are at risk to develop infection and bleeding. Current trends in the diagnosis and treatment of diverticular disease are essential for the clinician to understand in order to appropriately and safely manage the condition. Course Purpose To provide nursing professionals with knowledge to care for patients with diverticular disease. nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 3 Target Audience Advanced Practice Registered Nurses and Registered Nurses (Interdisciplinary Health Team Members, including Vocational Nurses and Medical Assistants may obtain a Certificate of Completion) Course Author & Planning Team Conflict of Interest Disclosures Elizabeth Boldon, RN, MSN, William S. Cook, PhD, Douglas Lawrence, MA, Susan DePasquale, MSN, FPMHNP-BC – all have no disclosures Acknowledgement of Commercial Support There is no commercial support for this course. Activity Review Information Reviewed by Susan DePasquale, MSN, FPMHNP-BC Release Date: 1/7/2016 Termination Date: 1/7/2019 Please take time to complete a self-assessment of knowledge, on page 4, sample questions before reading the article. Opportunity to complete a self-assessment of knowledge learned will be provided at the end of the course. nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 4 1. Diverticulosis specifically describes a. the presence of diverticula with symptoms. b. the presence of diverticula. c. the presence of diverticula with diverticular bleeding. d. inflammation of a diverticulum. 2. Inflammation of a diverticulum, known as ___________________ occurs when there is thinning and breakdown of the diverticular wall. a. diverticulosis b. colitis c. diverticulitis d. diverticular bleeding 3. A fistula is a. a localized collection of pus. b. an abnormal tract between two areas that are not normally connected. c. a blockage of the colon. d. an infection around the abdominal organ. 4. Sepsis is defined as a. an abnormal tract between two areas that are not normally connected. b. an infection around the abdominal organ. c. a blockage of the colon. d. an overwhelming body-wide infection. 5. Diverticular bleeding occurs a. when a small artery in a diverticulum erodes/bleeds into the colon. b. in 25% of cases of simple diverticulitis. c. in 75 percent of all cases of diverticulitis. d. All of the above. nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 5 Introduction Diverticular disease of the colon is an important cause of hospital admissions and a significant contributor to healthcare costs in the United States. Diverticular disease consists of three conditions that involve the development of small sacs or pockets in the wall of the colon (called diverticulum) including diverticulosis, diverticular bleeding, and diverticulitis.3 This course will describe all three of these conditions, as well as their symptoms, causes, risk factors, diagnosis, complications and treatment. What Is Diverticular Disease? Diverticular disease is defined as clinically significant and symptomatic diverticulosis due to diverticular bleeding, diverticulitis, segmental colitis associated with diverticula, or symptomatic uncomplicated diverticular disease. Diverticulosis Diverticulosis merely describes the presence of diverticula. Diverticulosis is often found during a test done for other reasons, such as flexible sigmoidoscopy, colonoscopy, or barium enema. Most people with diverticulosis have no symptoms and will remain symptom free for the rest of their lives.3 A person with diverticulosis may have diverticulitis, or diverticular bleeding. nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 6 Diverticulitis Inflammation of a diverticulum (diverticulitis) occurs when there is thinning and breakdown of the diverticular wall. This may be caused by increased pressure within the colon or by hardened particles of stool, which can become lodged within the diverticulum. The symptoms of diverticulitis depend upon the degree of inflammation present. The most common symptom is pain in the left lower abdomen. Other symptoms can include nausea and vomiting, constipation, diarrhea, and urinary symptoms such as pain or burning when urinating or the frequent need to urinate. Diverticulitis is divided into simple and complicated forms. Simple diverticulitis, which accounts for 75 percent of cases, is not associated with complications and typically responds to medical treatment without surgery. Complicated diverticulitis occurs in 25 percent of cases and usually requires surgery. Complications associated with diverticulitis can include the following:3 o Abscess – a localized collection of pus o Fistula – an abnormal tract between two areas that are not normally connected (i.e., bowel and bladder) o Obstruction – a blockage of the colon o Peritonitis – infection involving the space around the abdominal organ o Sepsis – overwhelming body-wide infection that can lead to failure of multiple organs nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 7 Diverticular Bleeding Diverticular bleeding occurs when a small artery located within a diverticulum is eroded and bleeds into the colon. Diverticular bleeding usually causes painless bleeding from the rectum. In approximately 50 percent of cases, the person will see maroon or bright red blood with bowel movements.3,4 Symptoms Of Diverticular Disease People with diverticulitis may have many symptoms, the most common of which is pain in the lower left side of the abdomen. The pain is usually severe and comes on suddenly, though it can also be mild and then worsen over several days. The intensity of the pain can fluctuate. Diverticulitis may also cause: fevers and chills nausea or vomiting a change in bowel habits — constipation or diarrhea diverticular bleeding In most cases, people with diverticular bleeding suddenly have a large amount of red or maroon-colored blood in their stool. Diverticular bleeding may also cause:1 weakness dizziness or light-headedness abdominal cramping nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 8 Causes Of Diverticular Disease Diverticulosis is often found during tests performed for other reasons.4 Barium enema This is an x-ray study that uses barium in an enema to view the outline of the lower intestinal tract. This is an older test and has been largely replaced by computed tomography (CT) scan. Flexible sigmoidoscopy This is an examination of the inside of the sigmoid colon with a thin, flexible tube that contains a camera. Colonoscopy This is an examination of the inside of the entire colon. CT scan A CT scan is often used to diagnose diverticulitis and its complications. If diverticulitis (not just diverticulosis) is suspected, the above three tests should not be used because of the risk of perforation. Scientists are not certain what causes diverticulosis and diverticular disease. For more than 50 years, the most widely accepted theory was that a lowfiber diet led to diverticulosis and diverticular disease. Diverticulosis and diverticular disease were first noticed in the United States in the early 1900s, around the time processed foods were introduced into the American diet. Consumption of processed foods greatly reduced Americans’ fiber intake. nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 9 Diverticulosis and diverticular disease are common in Western and industrialized countries — particularly the United States, England, and Australia — where low-fiber diets are common. The condition is rare in Asia and Africa, where most people eat high-fiber diets. Two large studies also indicate that a low-fiber diet may increase the chance of developing diverticular disease. However, a recent study found that a low-fiber diet was not associated with diverticulosis and that a high-fiber diet and more frequent bowel movements may be linked to an increased rather than decreased chance of diverticula.1 Other studies have focused on the role of decreased levels of the neurotransmitter serotonin in causing decreased relaxation and increased spasms of the colon muscle. However, more studies are needed in this area. Studies have also found links between diverticular disease and obesity, lack of exercise, smoking, and certain medications including nonsteroidal antiinflammatory drugs, such as aspirin, and steroids. Scientists agree that with diverticulitis, inflammation may begin when bacteria or stool get caught in a diverticulum. In the colon, inflammation also may be caused by a decrease in healthy bacteria and an increase in disease-causing bacteria. This change in the bacteria may permit chronic inflammation to develop in the colon.1 Risk Factors For Diverticular Disease Environmental and lifestyle factors are important risk factors for diverticular disease.3,4 nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 10 Diet Fiber The role of fiber in the development of diverticulosis is unclear. Several early studies suggested that low dietary fiber predisposes to the development of diverticular disease, but other studies have been conflicting. Fiber also does not reduce symptoms in patients with symptomatic uncomplicated diverticular disease. However, dietary fiber and a vegetarian diet may reduce the incidence of symptomatic diverticular disease by decreasing intestinal inflammation and altering the intestinal microbiota. Fat and Red Meat In one study, the risk of diverticular disease was significantly increased with diets that were low in fiber and were high in total fat or red meat as compared with diets that were low in both fiber and total fat or red meat. Seeds and Nuts Nut, corn, and popcorn consumption are not associated with an increase in risk of diverticulosis, diverticulitis or diverticular bleeding. In addition, no association has been found between consumption of corn and diverticulitis or between nut, popcorn, or corn consumption and diverticular bleeding or uncomplicated diverticulosis. nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 11 Physical Activity It is unclear if lack of vigorous exercise is a risk factor for diverticular disease. However, vigorous physical activity appears to reduce the risk of diverticulitis and diverticular bleeding. Obesity Obesity has been associated with an increase in risk of both diverticulitis and diverticular bleeding. Other Current smokers appear to be at increased risk for perforated diverticulitis and a diverticular abscess as compared with nonsmokers. Caffeine and alcohol are not associated with an increased risk for symptomatic diverticular disease. Several medications are associated with an increased risk of diverticulitis and diverticular bleeding including nonsteroidal anti-inflammatory drugs, steroids, and opiate. In contrast, statins may be associated with a decreased risk of diverticular perforation. In addition, higher levels of vitamin D have been associated with a reduced risk of hospitalization for diverticulitis. Diagnosis Of Diverticular Disease Based on symptoms and severity of illness, a person may be evaluated and diagnosed by a primary care physician, an emergency department physician, nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 12 a surgeon, or a gastroenterologist. The health care provider will ask about the person’s health, symptoms, bowel habits, diet, and medications, and will perform a physical exam, which may include a rectal exam. A rectal exam is performed in the health care provider’s office. To perform the exam, the health care provider asks the person to bend over a table or lie on one side while holding the knees close to the chest. The health care provider slides a gloved, lubricated finger into the rectum. The exam is used to check for pain, bleeding, or a blockage in the intestine. The health care provider may schedule one or more of the following tests outlined below. Blood test: A blood test involves drawing a person’s blood at a health care provider’s office, a commercial facility, or a hospital and sending the sample to a lab for analysis. The hemoglobin and complete blood count (CBC) blood test can show the presence of inflammation or anemia — a condition in which red blood cells are fewer or smaller than normal, which prevents the body’s cells from getting enough oxygen. Computerized tomography (CT) scan: A CT scan of the colon is the most common test used to diagnose diverticular disease. CT scans use a combination of X-rays and computer technology to create three-dimensional (3–D) images. For a CT scan, the person may be given a solution to drink and an injection of a special dye, called contrast medium. CT scans require the person to lie on a table that slides into a tunnel-shaped device where the nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 13 X-rays are taken. The procedure is performed in an outpatient center or a hospital by an X-ray technician, and a radiologist interprets the images. Anesthesia is not needed. CT scans can detect diverticulosis and confirm the diagnosis of diverticulitis. Lower gastrointestinal (GI) series: A lower GI series is an x-ray exam that is used to look at the large intestine. The test is performed at a hospital or an outpatient center by an x-ray technician, and a radiologist interprets the images. Anesthesia is not needed. The health care provider may provide written bowel prep instructions to follow at home before the test. The person may be asked to follow a clear liquid diet for one to three days before the procedure. A laxative or enema may be used before the test. A laxative is medication that loosens stool and increases bowel movements. An enema involves flushing water or laxative into the rectum using a special squirt bottle. These medications cause diarrhea, so the person should stay close to a bathroom during the bowel prep. For the test, the person will lie on a table while the radiologist inserts a flexible tube into the person’s anus. The colon is filled with barium, making signs of diverticular disease show up more clearly on X-rays. nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 14 For several days, traces of barium in the large intestine can cause stools to be white or light colored. Enemas and repeated bowel movements may cause anal soreness. A health care provider will provide specific instructions about eating and drinking after the test. Colonoscopy: This test is performed at a hospital or an outpatient center by a gastroenterologist. Before the test, the person’s health care provider will provide written bowel prep instructions to follow at home. The person may need to follow a clear liquid diet for one to three days before the test. The person may also need to take laxatives and enemas the evening before the test. In most cases, light anesthesia, and possibly pain medication, will help a patient relax for the test. The patient lies on a table while the gastroenterologist inserts a flexible tube into the anus. A small camera on the tube sends a video image of the intestinal lining to a computer screen. The test can show diverticulosis and diverticular disease. Cramping or bloating may occur during the first hour after the test. Driving is not permitted for 24 hours after the test to give the anesthesia time to wear off. Before the appointment, a patient should make plans for a ride home. Full recovery is expected by the next day, and people should be able to go back to their normal diet.1 nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 15 Complications Of Diverticular Disease About 25 percent of people with acute diverticulitis develop complications, which may include:2 An abscess, which occurs when pus collects in the pouch A perforation, a small tear or hole in the diverticula A blockage in the colon or small intestine caused by scarring An abnormal passageway (fistula) between sections of bowel or the bowel and bladder Peritonitis, a medical emergency that requires immediate care, which can occur if the infected or inflamed pouch ruptures, spilling intestinal contents into the abdominal cavity Abscess, Perforation, and Peritonitis Antibiotic treatment of diverticulitis usually prevents or treats an abscess. If the abscess is large or does not clear up with antibiotics, it may need to be drained. After giving the person numbing medication, a radiologist inserts a needle through the skin to the abscess and then drains the fluid through a catheter. An abdominal ultrasound or a CT scan usually is done prior to deciding the procedure. A person with a perforation usually needs surgery to repair the tear or hole. Sometimes, a person needs surgery to remove a small part of the intestine if the perforation cannot be repaired. A person with peritonitis may be extremely ill, with nausea, vomiting, fever, and severe abdominal tenderness. This condition requires immediate surgery nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 16 to clean the abdominal cavity and possibly a colon resection at a later date after a course of antibiotics. A blood transfusion may be needed if the person has lost a significant amount of blood. Without prompt treatment, peritonitis can be fatal.1 Fistula Diverticulitis-related infection may lead to one or more fistulas. Fistulas usually form between the colon and the bladder, small intestine, or skin. The most common type of fistula occurs between the colon and the bladder. Fistulas can be corrected with a colon resection and removal of the fistula. Intestinal Obstruction Diverticulitis-related inflammation or scarring caused by past inflammation may lead to intestinal obstruction. If the intestine is completely blocked, emergency surgery is necessary, with possible colon resection. Partial blockage is not an emergency, so the surgery or other procedures to correct it can be scheduled. When urgent surgery with colon resection is necessary for diverticulitis, two procedures may be needed because it is not safe to rejoin the colon right away. During the colon resection, the surgeon performs a temporary colostomy, creating an opening, or stoma, in the abdomen. The end of the colon is connected to the opening to allow normal eating while healing occurs. Stool is collected in a pouch attached to the stoma on the abdominal wall. In the second surgery, several months later, the surgeon rejoins the ends of the colon and closes the stoma.1 nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 17 Treatment Of Diverticular Disease People with diverticulosis who do not have symptoms do not require treatment. However, most clinicians recommend increasing fiber in the diet, which can help to bulk the stools and possibly prevent the development of new diverticula, diverticulitis, or diverticular bleeding. Fiber is not proven to prevent these conditions in all patients but may help to control recurrent episodes in some.3,4 Fiber Increased fiber is recommended in the treatment of diverticular disease. Fruits and vegetables are a good source of fiber. Seeds and Nuts Patients with diverticular disease have historically been advised to avoid whole pieces of fiber (such as seeds, corn, and nuts) because of concern that these foods could cause an episode of diverticulitis. However, this belief is completely unproven. Current recommendations do not suggest that patients with diverticulosis avoid seeds, corn, or nuts. Medications A number of studies suggest the medication mesalazine (Asacol), given either continuously or in cycles, may be effective at reducing abdominal pain and GI symptoms of diverticulosis. Research has also shown that combining mesalazine with the antibiotic rifaximin (Xifaxan) can be significantly more nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 18 effective than using rifaximin alone to improve a person’s symptoms and maintain periods of remission.1 Probiotics Although more research is needed, probiotics may help treat the symptoms of diverticulosis, prevent the onset of diverticulitis, and reduce the chance of recurrent symptoms. Probiotics are live bacteria, like those normally found in the GI tract. Probiotics can be found in dietary supplements — in capsules, tablets, and powders — and in some foods, such as yogurt.1 Diverticulitis Diverticulitis treatment depends upon the severity of the symptoms. Home treatment Mild symptoms of diverticulitis (mild abdominal pain, usually left lower abdomen), can be treated at home with a clear liquid diet and oral antibiotics. However, if one or more of the following signs or symptoms develop, one should seek immediate medical attention: Temperature >100.1°F (38°C) Worsening or severe abdominal pain An inability to tolerate fluids nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 19 Hospital treatment Moderate to severe symptoms, may require hospitalization for treatment. During this time, the patient will not be allowed to eat or drink; IV fluids and antibiotics will be administered. If a colon abscess develops, the patient may need to have the abscess drained. This is usually performed by placing a drainage tube across the abdominal wall or by surgically opening the affected area. Surgery If a generalized infection in the abdomen develops, (peritonitis), an emergency operation is usually required. A two-part operation may be necessary in some cases. The first operation involves removal of the diseased colon and creation of a colostomy. A colostomy is an opening between the colon and the skin, where a bag is attached to collect waste from the intestine. The lower end of the colon is temporarily sewed closed to allow it to heal. Approximately three to six months later, a second operation is performed to reconnect the two parts of the colon and close the opening in the skin. The patient will then be able to empty the bowel through the rectum. Sometimes patients require up to a year to recover from the first operation, depending on how sick they were. nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 20 In non-emergency situations, the diseased area of the colon can be removed and the two ends of the colon can be reconnected in one operation, without the need for a colostomy. An operation to remove the diseased area of the colon may not be necessary if the patient improves with medical therapy. However, people who are treated with an operation are felt to be cured, since only 15 percent of people develop further diverticulosis after surgery and only 2 to 11 percent of people need further surgery.4 Thus, surgery may be recommended for people with repeated attacks of diverticulitis or if there are severe or repeated episodes of bleeding. The decision depends in part upon other medical conditions and ability to undergo surgery. Some healthcare providers recommend surgery after the first attack of diverticulitis in people who are less than 40 to 50 years. The reason for this is that the disease may be more severe in this age group and there may be an increased risk of recurrent disease that will ultimately require surgery. Thus, having surgery at a young age could potentially eliminate the chances of developing worsened disease.4 In many cases, an elective operation can be performed laparoscopically, using small incisions, rather than the typical vertical abdominal incision. Laparoscopic surgery usually allows for a faster recovery and a shorter hospital stay. nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 21 Diverticular Bleeding Diverticular bleeding is rare. Bleeding can be severe; however, it may stop by itself and not require treatment. A person who has bleeding from the rectum, even a small amount, should see a health care provider right away. To treat the bleeding, a colonoscopy may be performed to identify the location of and stop the bleeding. A CT scan or angiogram also may be used to identify the site of the bleeding. A traditional angiogram is a special kind of X-ray in which a thin, flexible tube called a catheter is threaded through a large artery, often from the groin, to the area of bleeding. Contrast medium is injected through the catheter so the artery shows up more clearly on the X-ray. The procedure is performed in a hospital or an outpatient center by an X-ray technician, and a radiologist interprets the images. Anesthesia is not needed, though a sedative may be given to lessen anxiety during the procedure. If the bleeding does not stop, abdominal surgery with a colon resection may be necessary. In a colon resection, the surgeon removes the affected part of the colon and joins the remaining ends of the colon together; general anesthesia is used. A blood transfusion may be needed if the person has lost a significant amount of blood.1 Prognosis Of Diverticular Disease Diverticulosis Over time, diverticulosis may cause no problem or it may cause episodes of bleeding and/or diverticulitis. Approximately 15 to 25 percent of people with nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 22 diverticulosis will develop diverticulitis, while 5 to 15 percent will develop diverticular bleeding. Diverticulitis Approximately 85 percent of people with uncomplicated diverticulitis will respond to medical treatment, while approximately 15 percent of patients will need an operation. After successful treatment for a first attack of diverticulitis, one-third of patients will remain asymptomatic, one-third will have episodic cramps without diverticulitis, and one-third will go on to have a second attack of diverticulitis. The prognosis tends to remain similar following a second attack of diverticulitis. Only 10 percent of people remain symptom-free after a second attack. Subsequent attacks tend to be of similar severity, not increasing in severity as previously believed.4 Prevention Of Diverticular Disease To prevent diverticular disease or reduce the complications from it, it is important to maintain good bowel habits. This includes having regular bowel movements and avoiding constipation and straining. Eating appropriate amounts of the right types of fiber and drinking plenty of water and exercising regularly will help keep bowels regulated. The American Dietetic Association recommends 20 to 35 grams of fiber a day. Every person, regardless of the presence of diverticula, should try to nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 23 consume 20 to 35 grams of fiber every day. Fiber is the indigestible part of plant foods. High-fiber foods include whole grain breads, cereals, and crackers, berries, fruit, vegetables (such as broccoli, cabbage, spinach, carrots, asparagus, squash, and beans), brown rice, bran products, and cooked dried peas and beans, among other foods. Drinking eight 8-ounce glasses of water a day, monitoring changes in bowel movements (from constipation to diarrhea) and getting enough rest and sleep, are other ways to prevent diverticular disease.2 Summary In summary, diverticular disease consists of three conditions that involve the development of small sacs or pockets in the wall of the colon diverticulum) including diverticulosis, diverticular bleeding, and diverticulitis. This course has discussed these conditions, as well as their symptoms, causes, risk factors, diagnosis, complications and treatment. Please take time to help NurseCe4Less.com course planners evaluate the nursing knowledge needs met by completing the self-assessment of Knowledge Questions after reading the article, and providing feedback in the online course evaluation. Completing the study questions is optional and is NOT a course requirement. nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 24 1. Diverticulosis specifically describes a. the presence of diverticula with symptoms. b. the presence of diverticula. c. the presence of diverticula with diverticular bleeding. d. inflammation of a diverticulum. 2. Inflammation of a diverticulum, known as ____________ occurs when there is thinning and breakdown of the diverticular wall. a. diverticulosis b. colitis c. diverticulitis d. diverticular bleeding 3. A fistula is a. a localized collection of pus. b. an abnormal tract between two areas that are not normally connected. c. a blockage of the colon. d. an infection around the abdominal organ. 4. Sepsis is defined as a. an abnormal tract between two areas that are not normally connected. b. an infection around the abdominal organ. c. a blockage of the colon. d. an overwhelming body-wide infection. 5. Diverticular bleeding occurs a. when a small artery in a diverticulum erodes and bleeds into the colon. b. in 25% of cases of simple diverticulitis. c. in 75 percent of all cases of diverticulitis. d. in all of the above. nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 25 6. True or False: A recent study found that a low-fiber diet was associated with diverticulosis and an increased chance of diverticula. a. True. b. False. 7. In the colon, inflammation may be caused by ________________________. a. a decrease in healthy bacteria. b. a decrease in disease-causing bacteria. c. an increase in disease-causing bacteria. d. both a and c. 8. ____________ has been associated with an increase in risk of both diverticulitis and diverticular bleeding. a. A low-fiber diet b. Lack of exercise c. Obesity d. Corn or popcorn consumption 9. ____________ appears to increase the risk for perforated diverticulitis and a diverticular abscess. a. Smoking b. Consuming caffeine c. Alcohol consumption d. Inactivity 10. In testing for diverticular disease, a blood test may be ordered by the healthcare provider to determine a. the presence of diverticula. b. the level of healthy bacteria. c. the presence of inflammation or anemia. d. levels of blood-alcohol. nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 26 11. Which of the following is the most common test used to diagnose diverticular disease? a. Flexible sigmoidoscopy b. Computerized tomography (“CT”) scan of the colon c. Lower gastrointestinal (“GI”) series d. Colonoscopy 12. For several days, the patient’s stools may be white or lightcolored after which procedure? a. Lower gastrointestinal (“GI”) series b. Colonoscopy c. CT scan of the colon d. Enema. 13. ______________________ is/are associated with an increased risk of diverticulitis and diverticular bleeding. a. Statins b. Higher levels of vitamin D c. Alcohol consumption d. Steroids 14. One complication of acute diverticulitis may be ________________, which involves spilling intestinal contents into the abdominal cavity. a. peritonitis b. sepsis c. a fistula d. colitis nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 27 15. The usual treatment for a patient with diverticulitis who develops an abscess is a. to drain the abscess. b. to surgically remove the abscess. c. to remove a small part of the intestine. d. to treat the patient with antibiotics. 16. Which of the following is true of diverticular bleeding? a. It is common for patients with diverticulitis. b. It may stop by itself and not require treatment. c. Bleeding is never severe. d. A patient need only see a healthcare provider if the bleeding is severe. 17. The American Dietetic Association recommends __________ grams of fiber a day. a. more than 50 b. 20 to 35 c. 10 d. 40 to 50 18. An procedure called __________________________ uses small incisions, rather than the typical vertical abdominal incision, to treat diverticulitis. a. an angiogram b. flexible sigmoidoscopy c. laparoscopic surgery d. a colostomy nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 28 19. Diverticular disease generally involves the presence of _________________ in the wall of the colon. a. disease-causing bacteria b. bleeding c. small sacs or pockets d. an abscess 20. True or False: When treating diverticulosis, combining mesalazine with the antibiotic rifaximin (Xifaxan) can be significantly more effective than using rifaximin alone. a. True b. False References Section The reference section of in-text citations include published works intended as helpful material for further reading. Unpublished works and personal communications are not included in this section, although may appear within the study text. 1. 2. 3. 4. Diverticular Disease (2013) National Institute of Diabetes and Digestive and Kidney Diseases. Retrieved December 28, 2015 from www.niddk.nih.gov Diverticulitis (2014) Mayo Foundation for Medical Education and Research. Retrieved December 18, 2015 from www.mayoclinic.org Pemberton, J.H. & Young-Fadok, T. (2015) Clinical manifestations and diagnosis of acute diverticulitis in adults, in Lamont, J.T. (Ed.), UpToDate. Waltham, Mass.: UpToDate. Retrieved December 19, 2015 from www.uptodate.com Young-Fadok, T. & Pemberton, J.H. (2015) Colonic diverticulosis and diverticular disease: Epidemiology, risk factors, and pathogenesis, in Friedman, L.S. (Ed.), UpToDate. Waltham, Mass.: UpToDate. Retrieved December 19, 2015 from www.uptodate.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com nursece4less.com 29 The information presented in this course is intended solely for the use of healthcare professionals taking this course, for credit, from NurseCe4Less.com. The information is designed to assist healthcare professionals, including nurses, in addressing issues associated with healthcare. The information provided in this course is general in nature, and is not designed to address any specific situation. This publication in no way absolves facilities of their responsibility for the appropriate orientation of healthcare professionals. Hospitals or other organizations using this publication as a part of their own orientation processes should review the contents of this publication to ensure accuracy and compliance before using this publication. 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