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Chapter 9.1 Notes “Cellular Respiration: An Overview” Food serves as a source of energy for us. o When you are hungry you feel weak because you are lacking energy that food provides. o Food is made of chemical energy (a type of potential energy). When the bonds within food are broken down, energy is released. The energy within food is measured in calories. o 1 calorie = the amount of energy needed to raise 1g of water 1°Celsius o A Calorie on food labels = 1 kilocalorie (1000 calories) How our bodies release the energy that food contains: Cellular Respiration – the process that releases energy from food in the presence of oxygen Oxygen + Glucose Carbon Dioxide + Water + Energy 6 O2 + C6H12O6 6 CO2 + 6 H2O + Energy This reaction occurs in many separate steps. The above equation is a summary of the reactions that take place. Three stages of cellular respiration: o Glycolysis o The Krebs cycle o The Electron Transport Chain Aerobic Respiration: Krebs cycle and electron transport chain Requires oxygen Anaerobic Respiration: Glycolysis Oxygen is not required Photosynthesis and respiration are opposite processes. Photosynthesis “deposits” energy (in the form of a fuel – glucose). Cellular respiration “withdraws” energy (by breaking down glucose). Photosynthesis removes CO2. Cellular respiration adds it back to the atmosphere. Photosynthesis releases O2 into the atmosphere. Cellular respiration removes it. Photosynthesis only occurs in autotrophic organisms (green plants, algae, some bacteria). Cellular respiration occurs in nearly all life (plants, protists, animals, most bacteria). Chapter 9.2 “The Process of Cellular Respiration” Glycolysis – occurs in the cytoplasm Each molecule of glucose that is broken down results in the formation 2 molecules of ATP and 2 molecules of NADH. o Glucose – a 6-Carbon sugar is broken down to two 3-Carbon compounds (pyruvic acid – pyruvate) o 4 molecules of ATP are produced o 2 molecules of NADH are produced from NAD+. These enter the electron transport chain. o Explain why there is a net yield of two ATP, not 4, in glycolysis. Krebs Cycle: aerobic – requires oxygen most of the energy from glucose is in pyruvate molecules from glycolysis The series of reactions that break down pyruvate into carbon dioxide is the Krebs cycle (aka. tricarboxylic acid cycle (TCA) or citric acid cycle). First each pyruvate reacts with coenzyme A (CoA) to form acetyl CoA. o Acetyl CoA moves into the mitochondrial matrix – innermost compartment of the mitochondria. o Acetyl CoA combines with a 4-C compound to make citric acid. o Citric acid is broken down to release 2 carbon dioxide and 1 ATP. o Net gain of 2 ATP (because this starts with 2 pyruvate molecules). o FADH2 and NADH are electron carriers that enter into the electron transport chain. Electron Transport: high energy electrons are used to convert ADP into ATP These electrons are generated from glycolysis and the Krebs cycle and are carried by electron carriers – NAD+ and FAD+. Aerobic Most ATP is produced Occurs along the inner mitochondrial membrane in eukaryotes and along the cell membrane of prokaryotes. ATP produced using chemiosmosis – ATP synthase in the membrane spins as H+ ions cross through. With each rotation a phosphate group is added to an ADP. On average each pair of electrons that pass down the electron transport chain generate enough energy to produce 3 ATP Oxygen is the final electron acceptor. Protons and electrons are transferred to oxygen to form water. 36 ATP produced from cellular respiration