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Page 1 of 10 Cellular Organization You have just finished learning about cell. Now it is time to move up in complexity. There are many different types of cells (muscle, brain, blood, bone, heart, skin, etc.). They all look different and carry out different functions. Their shape helps them with their job. Cells don't work along though, they work together in groups, called tissues. Tissues work together to perform a specific job. Tissues that work together are called organs. Activity #1: Working with a small group (2-3) brainstorm as many different organs of the human body as you can (hint: there are as many as 60!) Groups of organs that work together to carry out specific jobs in the body too. Groups of organs that work together are called organ systems. Organ systems work together to form a complete functioning organism (animal, plant, fungus, etc.) Activity #2: Working with the same group brainstorm as many different organ systems of the human body as you can (hint: there are 10 major ones!) Page 2 of 10 Activity #3: Match Organ systems to their function Organ System organ system # Description and Function 1. Circulatory (a) a system made up of the brain, spinal cord, and nerves that receives and interprets stimuli and transmits impulses to organs 2. Digestive (b) a system of blood, blood vessels, lymphatics, and heart concerned with the circulation of the blood and lymph 3. Endocrine (c) a system consisting especially of the nose, larynx, trachea, bronchi, and lungs that controls breathing 4. Integumentary (d) a system comprising the kidneys, ureters, urinary bladder, and urethra that regulates urination 5. Muscular (e) a system that consists of the bones, cartilage, and joints that supports and protects the body, produces blood cells, and stores minerals 6. Nervous (f) a system involving the mouth, stomach, and intestines that is concerned with the ingestion, digestion, and absorption of food 7. Reproductive (g) a system involving especially the pituitary and thyroid glands, ovaries, and testes that produces secretions and helps control moods, growth and development, and metabolism. 8. Respiratory (h) a system consisting of the skin, hair, nails, and sweat glands that protects the body and controls body temperature 9. Skeletal (i) a system involving organs such as the uterus, penis, ovaries, and testes that deals with making babies 10. Urinary (j) a system made up of muscle tissue that helps move the body and move materials through the body Page 3 of 10 Skin as an Organ INTRODUCTION Did you know that skin is the largest body organ? In this activity, you'll examine the skin and how it functions as an organ and as part of a larger body system. EXPLORATION Go to Organ Systems and read about each of the different organ systems. Remember that the human body is made up of many organ systems that work together to support body functions. You will discuss the different organ systems and their parts and functions when you are finished reading. Take notes so that you can participate in the discussion. Next, go to and read the Integumentary System site to take a closer look at the skin as an organ and how it interacts with other systems of the body. As you’re reading, take notes so that you can answer these questions: What structures are associated with the integumentary system? What are the functions of the integumentary system? What part does the skin play in your immune system? How does the integumentary system interact with the digestive system? Why is it that patches placed on the skin can be used to deliver medications to the bloodstream? What role does your skin play in the regulation of body temperature? How important is your skin for the functioning of the nervous system? As you read the following pages, take notes so that you can answer these questions: 1. What parts of the integumentary system are made up of dead epidermal cells? 2. What is the purpose of the excretory system? 3. What primary organs are involved in the excretion process? 4. What types of waste products are removed through the skin? 5. What organ systems are involved in the creation and excretion of urine? Page 4 of 10 Organ Systems INTRODUCTION The human body is made up of several organ systems that all work together as a unit to make sure the body keeps functioning. There are ten major organ systems in the body, each of which plays a different role in helping the body work. CIRCULATORY SYSTEM This system is made up of the heart, blood, blood vessels, and lymphatics. It is the body’s delivery system, concerned with circulating blood to deliver oxygen and nutrients to every part of the body. DIGESTIVE SYSTEM The purpose of the digestive system is to turn the food you eat into something useful for the body. When you eat, your body uses this system to digest food so your cells can use it to make energy. The organs involved in this system include the mouth, stomach, and intestines. ENDOCRINE SYSTEM This system is made up of a collection of glands, including the pituitary and thyroid glands, as well as the ovaries and testes. It regulates, coordinates, and controls a number of body functions by secreting chemicals into the bloodstream. These secretions help control moods, growth and development, and metabolism. INTEGUMENTARY SYSTEM This system consists of the skin, hair, nails, and sweat glands. Its main function is to act as a barrier to protect the body from the outside world. It also functions to retain body fluids, protect against disease, eliminate waste products, and regulate body temperature. MUSCULAR SYSTEM This system is made up of muscle tissue that helps move the body and move materials through the body. Quite simply, muscles move you. Muscles are bundles of cells and fibers that work in a simple way: they tighten up and relax. NERVOUS SYSTEM The nervous system is the control center of the human body. It is made up of the brain, spinal cord, and nerves. It receives and interprets stimuli and transmits impulses to organs. Your brain uses the information it receives to coordinate all of your actions and reactions. REPRODUCTIVE SYSTEM The human reproductive system ensures that humans are able to reproduce and survive as a species. It is made up of organs such as the uterus, penis, ovaries, and testes. RESPIRATORY SYSTEM The primary function of the respiratory system is to supply the blood with oxygen in order for the blood to deliver oxygen to all parts of the body. The respiratory system does this through breathing. It consists of the nose, larynx, trachea, diaphragm, bronchi, and lungs. SKELETAL SYSTEM The skeletal system provides the shape and form for our bodies in addition to supporting and protecting our bodies, allowing bodily movement, producing blood cells, and storing minerals. This system consists of bones, cartilage, and joints. URINARY SYSTEM The purpose of the urinary system is to filter out excess fluid and other substances from your bloodstream. Some fluid gets reabsorbed by your body but most gets expelled as urine. The organs found in this system are the kidneys, ureters, urinary bladder, and urethra. Page 5 of 10 The Anatomy of Skin The skin is an ever-changing organ that contains many specialized cells and structures. The skin functions as a protective barrier that faces a sometimeshostile outside environment. It is also very involved in maintaining the proper temperature for the body to function well. It gathers sensory information from the environment, and plays an active role in the immune system protecting us from disease. Understanding how the skin can function in these many ways starts with understanding the structure of the 3 layers of skin - the epidermis, dermis, and subcutaneous tissue. Epidermis The epidermis is the outer layer of skin. The thickness of the epidermis varies in different types of skin. It is the thinnest on the eyelids at .05 mm and the thickest on the palms and soles at 1.5 mm. The epidermis contains 5 layers of cells. The bottom layer, the stratum basale, has cells that are shaped like columns. In this layer the cells divide and push already formed cells into higher layers. As the cells move into the higher layers, they flatten and eventually die. The top layer of the epidermis, the stratum corneum, is made of dead, flat skin cells that shed about every 2 weeks. Specialized Epidermal Cells There are three types of specialized cells in the epidermis. The melanocyte produces pigment (melanin) The Langerhans' cell is the frontline defense of the immune system in the skin The Merkel's cell's function is not clearly known Page 6 of 10 Dermis The dermis also varies in thickness depending on the location of the skin. It is .3 mm on the eyelid and 3.0 mm on the back. The dermis is composed of three types of tissue that are present throughout not in layers. The types of tissue are: collagen elastic tissue Layers of the Dermis The two layers of the dermis are the papillary and reticular layers. The upper layer contains a thin arrangement of collagen fibers. The lower layer is thicker and made of thick collagen fibers that are arranged parallel to the surface of the skin. Specialized Dermal Cells The dermis contains many specialized cells and structures. The hair follicles are situated here with the erector pili muscle that attaches to each follicle. Sebaceous (oil) glands and apocrine (scent) glands are associated with the follicle. This layer also contains eccrine (sweat) glands, but they are not associated with hair follicles. Blood vessels and nerves course through this layer. The nerves transmit sensations of pain, itch, and temperature. There are also specialized nerve cells called Meissner's and Vater-Pacini corpuscles that transmit the sensations of touch and pressure. Subcutaneous Tissue The subcutaneous tissue is a layer of fat and connective tissue that houses larger blood vessels and nerves. This layer is important is the regulation of temperature of the skin itself and the body. The size of this layer varies throughout the body and from person to person. The skin is a complicated structure with many functions. If any of the structures in the skin are not working properly, a rash or abnormal sensation is the result. The whole specialty of dermatology is devoted to understanding the skin, what can go wrong, and what to do if something does go wrong. Page 7 of 10 Integumentary System Introduction The integumentary system consists of the skin, hair, nails, glands, and nerves. Its main function is to act as a barrier to protect the body from the outside world. It also functions to retain body fluids, protect against disease, eliminate waste products, and regulate body temperature. In order to do these things, the integumentary system works with all the other systems of your body, each of which has a role to play in maintaining the internal conditions that a human body needs to function properly. Functions of the Integumentary System The integumentary system has many functions, most of which are involved in protecting you and regulating your body’s internal functions in a variety of ways: 1. 2. 3. 4. 5. 6. 7. Protects the body's internal living tissues and organs Protects against invasion by infectious organisms Protects the body from dehydration Protects the body against abrupt changes in temperature Helps get rid of waste materials Acts as a receptor for touch, pressure, pain, heat, and cold Stores water and fat How does the integumentary system work with other systems? Your body is a complicated system that consists of many subsystems that help to keep it functioning properly. These subsystems serve a variety of purposes and require needed materials to function properly, as well as means of communicating information to other parts of the body. Thus, the skin and other parts of the integumentary system work with other systems in your body to maintain and support the conditions that your cells, tissues, and organs need to function properly. The skin is one of the first defense mechanisms in your immune system. Tiny glands in the skin secrete oils that enhance the barrier function of the skin. Immune cells live in the skin and provide the first line of defense against infections. By helping to make and absorb vitamin D, the integumentary system works with the digestive system to encourage the uptake of calcium from our diet. This substance enters the bloodstream though the capillary networks in the skin. Healthy functioning of your skin also is related to the digestive system because the digestion and assimilation of dietary fats and oils are essential for the body to be able to make the protective oils for the skin and hair. The integumentary system also works closely with the circulatory system and the surface capillaries through your body. Because certain substances can enter the bloodstream through the capillary networks in the skin, patches can be used to deliver medications in this manner for conditions ranging from heart problems (nitroglycerin) to smoking cessation (nicotine patches). The skin also is important in helping to regulate your body temperature. If you are too hot or too cold, your brain sends nerve impulses to the skin, which has three ways to either increase or decrease heat loss from the body's surface: hairs on the skin trap more warmth if they are standing up, and less if they are lying flat; glands under the skin secrete sweat onto the surface of the skin in order to increase heat loss by evaporation if the body is too hot; capillaries near the surface can open when your body needs to cool off and close when you need to conserve heat. Your skin plays a vital role in your body as regards the sense of touch. The nervous system depends on neurons embedded in your skin to sense the outside world. It processes input from your senses, including touch, and initiates actions based on those inputs. For example, when you stub your toe, nerve cells in the foot send signals up the leg, through the spinal cord, and up into the brain. The nerve cell connections in the brain sense these signals as pain. Page 8 of 10 As well as interacting with the body systems as explained above, the integumentary system also contributes to numerous physiological processes, especially those involved in the regulation of the body’s internal environment so as to maintain a stable condition. An example is provided by the way that the skin helps in temperature regulation by changes in the pattern of blood supply to the skin and by sweating, as mentioned above. Excretory System: Poison Protection If you knew there was poison hidden in your house, you would surely do everything possible to find and remove that poison. If you didn't, you and your family would slowly die. How would you find it? How would you remove it? You would probably figure out a system of searching and removing. That would be an excretory system. Your body does the same thing every day. Hidden throughout your body are dangerous poisons that must be removed in order for it to survive. The process of excretion involves finding and removing waste materials produced by the body. The primary organs of excretion are the lungs, kidneys, and skin. Waste gases are carried by blood traveling through the veins to the lungs where respiration takes place. Dead cells and sweat are removed from the body through the skin which is part of the integumentary system. Integumentary System: Cutting Dead Cells The body's integumentary system supports the excretory system in the removal of waste. Skin, hair, fingernails and toenails make up the system by which surface level wastes are removed. The skin protects the body and also provides for the removal of dead cells and sweat, which contains waste products. Hair, fingernails and toenails are actually accumulations of dead epidermal cells. As more cells die and need to be removed, the hair and nails grow. Activity #4: Now that you have read about the skin, answer the following questions: 1. What parts of the integumentary system are made up of dead epidermal cells? 2. What is the purpose of the excretory system? 3. What primary organs are involved in the excretion process? 4. What types of waste products are removed through the skin? 5. What organ systems are involved in the creation and excretion of urine? Page 9 of 10 Skin Connections REFLECTIONS ON LEARNING In this lesson, you have been learning about the integumentary and other organ systems and how these systems work together. Use your notes about what you have learned to help you complete this student sheet. Name the organ systems identified in this lesson. ________________________________________________________________________________________________ ________________________________________________________________________________________________ ________________________________________________________________________________________________ Describe the basic structure and functions of the skin (integumentary) organ system. Structure Function Page 10 of 10 Give specific examples of organ systems that interact with the integumentary system. Organ System Activity #5: How does it interact with the skin? Create your own 3D model of skin. Due: Monday, October 6th, 2014