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Class Starter Using the diagram of a football field, write a short paragraph describing how the players, the midfield line, and the goal posts compare to the structures of a cell involved in mitosis and cell division. Objectives • What are the phases of the eukaryotic cell cycle? • What are the four stages of mitosis? • How does cytokinesis occur? 10.2: Mitosis Eukaryotic Cell Cycle • The __________________ is a ____________________ sequence of cellular ___________________________________________ during the life of a cell. • The life of a eukaryotic cell cycles through phases of __________________, ____________________________, _______________________________, and _________________________________ and _____________________. • The cell cycle is made up of ________ phases. The first three phases together are known as ___________________________. The remaining two phases make up _______________________________. Interphase • During interphase, the cell is not dividing. It is ___________________________ to divide. • Different types of cells spend _________________________ amounts of time in interphase. • Cells that divide often, such as skin cells, spend _________ time in interphase. Cells that divide seldom, such as nerve cells, spend __________ of their time in interphase. • During the __________________________ (G1), a cell grows rapidly as the cell builds more _________________________. For most organisms, this phase occupies the major portion of the cell’s life. • During the ____________________________ (S), a cell’s __________ is copied. At the end of the S phase, the cell’s nucleus has _________________ as much DNA as it did in the G1 phase. • During the _______________________________ (G2), the cell continues to __________________________________ to divide. Hollow protein fibers called microtubules are organized in the cytoplasm during G2. • What is the cell cycle? Checkpoint – • What takes place during the cycle in eukaryotes? How many phases make up the cell cycle? – What are their names? • What are the 3 phases that make up interphase? • What happens in each phase? Cell Division • Each new cell requires a complete set of organelles, including a nucleus. • The process of dividing the nucleus into two daughter nuclei is called _________________. • The process of separating the organelles and the cytoplasm is called ___________________________. • During mitosis, the _____________________ divides to form _______________. Each nucleus contains a complete set of the cell’s _______________________. • The ________________________ breaks down briefly. The two sister chromatids of each chromosome are pulled to the ____________________ sides of the dividing cell. • As the nucleus divides, the ______________________ also begins to divide. • Each daughter cell receives about __________ of the original cell’s organelles. • During ____________________, the two daughter cells are physically separated. Checkpoint • What is the difference between mitosis and cytokinesis? • Summarize the events of cell division. • What is the end product? Stages of Mitosis Stage 1 Prophase • Within the nucleus, chromosomes begin to _________________ and become visible under a light microscope. • The nuclear membrane ________________________. Outside the nucleus, a special structure called the __________________ forms. The spindle is made up of several _________________________. • Cells have an organelle called the ________________________, which helps assemble the spindle. • In animal cells, the centrosome includes a pair of ______________________. • Before mitosis, the cell’s centrosome is duplicated. During prophase, the centrosomes move to ____________________________________ of the cell. Stage 2 Metaphase • During metaphase, the __________________________ are packaged into their most condensed form. • The nuclear membrane is fully __________________________, and the condensed chromosomes move to the ___________________ of the cell and line up along the cell’s equator. • Spindle fibers form a link between the poles and the _______________________ of each chromosome. Checkpoint • What is the first phase of mitosis? • What happens during this phase? • What is the second phase of mitosis? • What happens during this phase? Stage 3 Anaphase • Once all of the chromosomes are lined up, the spindle fibers ________________. • ___________________________ move toward opposite poles as the spindle fibers that are attached continue to shorten. • Each pole now has a full set of _________________________. Stage 4 Telophase • A ________________________ forms around the chromosomes at each pole of the cell. • Chromosomes, now at opposite poles, ______________ and change back to their original _____________________ form. • The __________________ dissolves and the _______________________ break down and disappear. • Mitosis is complete. Checkpoint • What is the third phase of mitosis? • What happens during this phase? • What is the last phase of mitosis? • What happens during this phase? Cytokinesis • As ___________________ ends, cytokinesis begins. The ___________________ is separated, and _________ cells are formed. • During cytokinesis, the ________________________ grows into the center of the cell and divides it into two __________________________ of equal size. • Each daughter cell has about half of the parent’s __________________________ _______________________________. • The end result of mitosis and cytokinesis is ______ genetically ___________cells in place of the original cell. Separating the Cytoplasm • ________________________ holding cell wall material line up across the ______________________ of the cell. • These vesicles fuse to form a large, membrane-bound cell wall called the __________________ • When it is completely formed, the cell plate separates the plant cell into ______ new plant cells. Continuing the Cell Cycle • After cytokinesis is complete, each cell enters the _____________ of interphase. • The daughter cells are about equal in size—about half the size of the original cell. • The activity of each cell continues because each has its own _________________ _______________. The _______________________ continues for each new cell. Checkpoint • When does cytokinesis begin? • Cytokinesis divides the cell contents in ____. • What is the result of this process? • How does cytokinesis in plants differ from animals? • After cytokinesis, what phase does the new cells enter?