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CONCISE GUIDE TO HUMAN ANATAMY EDITER Liu Zhiyu SHANDONG UNIVERSITY FORWORD This book is for the students, faculty and staff in studying and teaching of the Medical English Course to produce a study aid for human anatomy. The succinct text, some summaries of the organs, and the tabeles in the book are the results of long teaching experience. The contents of the book are closely connected the Text-Book of Human Anatomy in China. The chapters and sections are, as well as, the came in order as the Text-Book of Human Anatomy in Chinese. The book was written according to the Key Contents of Anatomical Outline of the country and the primary source for your education, but rather to serve as an aid in the integration of lecture, text review and examination, and for futher quick reference. EDITOR Liu Zhi-yu(刘执玉) 1996.6.26 CONTENTS Introduction……………………………………………………………………………………1 PART Ⅰ THE LOCOMOTOR SYSTEM Chapter 1 Osteology...……………………………………………………………………………3 Section 1 Introduction ……………………………………………………………………...3 Section 2 The Bones of the Trunk ………………………………………………………..4 Section 3 The Skull ………………………………………………………………………...6 Ⅰ. General View………………………………………………………………………6 Ⅱ. The Granial Cavity………………………………………………………………...7 Ⅲ. The External Aspect of the Base of the Skull..……………………………………8 Ⅳ. The Anterior Aspect of the Skull…………………………………………………..9 Ⅴ. The Skull at the Birth……………………………………………………………...9 Section 4 The Bones of The Limbs………………………………………………………..10 Ⅰ. The Bones of the Upper Limb……………………………………………………10 Ⅱ. The Bones of the Lower Limb ...…...……………………………………………12 Chapter 2 Arthrology ......………………………………………………………………………14 Section 1 Introduction……………………………………………………………………..14 Section 2 The Articulations of Axis Skeleton……………………………………………..15 Section 3 The Articulations of the Cranial Bones…………………………………………16 Section 4 The Articulations of the Appendicular Bones…………………………………..17 Ⅰ. The Joints of The Upper Limb…………………………………………………...17 Ⅱ.The Articulations of the Lower Limb…………………………………………….18 Chapter 3 Myology……………………………………………………………………………..21 Section 1 Introduction……………………………………………………………………..21 Section 2 The Muscles of the Trunk………………………………………………………22 Ⅰ. The Muscles of the Back…………………………………………………………22 Ⅱ. The Muscles of the Neck…………………………………………………………23 Ⅲ. The Muscles of the Thorax……………………………………………………….23 Ⅳ. The Diaphragm…………………………………………………………………...24 Ⅴ. The Muscles of the Abdomen.…...………………………………………………24 Section 3 The Muscles of the Head………………………………………………………..25 Section 4 The Muscles of the Upper Limb………………………………………………..26 Section 5 The Muscles of the Lower Limb………………………………………………..29 PART Ⅱ THE SPLANCHNOLOGY Chapter 1 Introduction………………………………………………………………………….33 Chapter 2 The Digestive System………………………………………………………………..35 Section 1 The Oral Cavity…………………………………………………………………35 Section 2 The Pharynx…………………………………………………………………….36 Section 3 The Esophagus………………………………………………………………….37 Section 4 The Stomach…………………………………………………………………….37 Section 5 The Small Intestine……………………………………………………………..38 Section 6 The Large Intestine……………………………………………………………...39 Section 7 The Liver………………………………………………………………………..40 Section 8 The Gallbladder and The Biliary Duct………………………………………….41 Section 9 The Pancreas……………………………………………………………………42 Chapter 3 The Respiratory System……………………………………………………………..43 Section 1 The Nose………………………………………………………………………..43 Section 2 The Pharyns and Larynx………………………………………………………..44 Section 3 The Trachea and Bronchi……………………………………………………….44 Section 4 The Lungs……………………………………………………………………….45 Section 5 The Pleura………………………………………………………………………45 Chapter 4 The Urinary System………………………………………………………………….47 Section 1 The Kidneys…………………………………………………………………….47 Section 2 The Ureters……………………………………………………………………...48 Section 3 The Urinary Bladder……………………………………………………………48 Section 4 The Urethra……………………………………………………………………..49 Chapter 5 The Male Reproductive System……………………………………………………..50 Chapter 6 The Female Reproductive System…………………………………………………...53 Chapter 7 The Peritoneum……………………………………………………………………...57 PART Ⅲ ANGIOLOGY Chapter 1 The Cardiovascular System………………………………………………………….60 Section 1 Introduction……………………………………………………………………..60 Ⅰ. The Composition…………………………………………………………………60 Ⅱ. The Cardiovascular Circuits……………………………………………………...60 Section 2 The Heart………………………………………………………………………..60 Ⅰ. The Position of the Heart………………………………………………………...60 Ⅱ. The External Morphology of the Heart…………………………………………..61 Ⅲ. The Internal Morphology of the Heart…………………………………………...61 Ⅳ. The Structure of the Heart………………………………………………………..63 Ⅴ. The Conducting System of the Heart…………………………………………….63 Ⅵ. The Vessels of the Heart………………………………………………………….64 Ⅶ. The Pericardium………………………………………………………………….65 Section 3 The Arteries……………………………………………………………………..66 Ⅰ. The Arteries of Pulmonary Circulation…………………………………………..66 Ⅱ. The Arteries of Systemic Circulation…………………………………………….66 Section 4 The Veins………………………………………………………………………..72 Ⅰ. The Veins of Pulmonary Circulation……………………………………………..72 Ⅱ. The Veins of Systemic Circulation……………………………………………….72 Chapter 2 The Lymphatic System………………………………………………………………78 Section 1 Introduction……………………………………………………………………..78 Ⅰ. The Composition…………………………………………………………………78 Ⅱ. The Character…………………………………………………………………….78 Section 2 The Lymphatic Ducts of the Body……………………………………………...79 Ⅰ. The Thoracic Duct………………………………………………………………..79 Ⅱ. The Right Lymphatic Duct……………………………………………………….80 Section 3 The Lymph Vessels an Nodes of the Body……………………………………...80 Ⅰ. The Lymph Vessels and Nodes of the Head and Neck…………………………80 Ⅱ. The Lymph Vessels and Nodes of the Upper Limb…………………………….81 Ⅲ. The Lymph Vessels and Nodes of the Thorax………………………………….81 Ⅳ. The Lymph Vessels and Nodes of the Abdomen……………………………….82 Ⅴ. The Lymph Vessels and Nodes of the Pelvis…………………………………...83 Ⅵ. The Lymph Vessels and Nodes of the Lower Limb……………………………83 Section 4 The Spleen………………………………………………………………………84 Ⅰ. The Position……………………………………………………………………...84 Ⅱ. The Shape………………………………………………………………………...84 Section 5 The Thymus……………………………………………………………………..84 PART Ⅳ THE SENSE ORGANS Chapter 1 Introduction………………………………………………………………………….85 Chapter 2 The Visual Apparatus………………………………………………………………...86 Section 1 The Eyeball……………………………………………………………………..86 Ⅰ. The Wall of the Eyeball…………………………………………………………..86 Ⅱ. The Contents of the Eyeball……………………………………………………...87 Section 2 The Accessory Apparatus of the Eyeball……………………………………….88 Ⅰ. The Eyelids or Palpebrae………………………………………………………...88 Ⅱ. The Conjunctiva………………………………………………………………….88 Ⅲ. The Lacrimal Apparatus …………………………………………………………89 Ⅳ. The Extraocular Muscles…………………………………………………………89 Section 3 The Blood Vessels of the Eye…………………………………………………...90 Ⅰ. The Arteries of the Eye ………………………………………………………….90 Ⅱ. The Veins of the Eye……………………………………………………………..90 Chapter 3 The Auditory and Vestibular Apparatus……………………………………………...91 Section 1 The External Ear………………………………………………………………..91 Ⅰ. The Auricle……………………………………………………………………….91 Ⅱ. The External Acoustic Meatus…………………………………………………...91 Section 2 The Middle Ear…………………………………………………………………92 Ⅰ. The Tympanic Cavity…………………………………………………………….92 Ⅱ. The Auditory Tube……………………………………………………………….93 Ⅲ. The Mastoid Antrum and Mastoid Air cells……………………………………...93 Section 3 The Internal Ear…………………………………………………………………93 Ⅰ. The Osseous Labyrinth…………………………………………………………..94 Ⅱ. The Membranous Labyrinth……………………………………………………...95 Ⅲ. The Internal Acoustic Meatus……………………………………………………95 PART Ⅴ THE NERVOUS SYSTEM Chapter 1 Introduction………………………………………………………………………….96 Chapter 2 The Perpheral Nervous System……………………………………………………...98 Section 1 The Spinal Nerves………………………………………………………………98 Ⅰ. The Cervical Plexus……………………………………………………………...99 Ⅱ. The Brachial Plexus…………………………………………………………….100 Ⅲ. The Ventral Rami of the Thoracic Nerves………………………………………102 Ⅳ. The Lumbar Plexus……………………………………………………………..102 Ⅴ. The Sacral Plexus……………………………………………………………….103 Section 2 The Cranial Nerves……………………………………………………………104 Ⅰ. The Olfactory Nerve……………………………………………………………106 Ⅱ. The Optic Nerve………………………………………………………………...106 Ⅲ. The Oculomotor Nerve…………………………………………………………106 Ⅳ. The Trochlear Nerve……………………………………………………………107 Ⅴ. The Trigeminal Nerve…………………………………………………………..107 Ⅵ. The Abducent Nerve……………………………………………………………109 Ⅶ. The Facial Nerve………………………………………………………………..109 Ⅷ. The Vestibulocochlear ( Auditory ) Nerve……………………………………...110 Ⅸ. The Glossopharyngeal Nerve…………………………………………………...111 Ⅹ. The Vagus Nerve………………………………………………………………..111 Ⅺ. The Accessory Nerve……………………………………………………………113 Ⅻ. The Hypoglossal Nerve…………………………………………………………114 Section 3 The Visceral Nervous System…………………………………………………114 Ⅰ. The Visceral Motor Nerves……………………………………………………..114 Ⅱ. The Visceral Sensory Nerves…………………………………………………...121 Chapter 3 The Central Nervous System……………………………………………………….122 Section 1 The Spinal Cord……………………………………………………………….122 Ⅰ. The External Features…………………………………………………………..122 Ⅱ. The Internal Structures………………………………………………………….123 Ⅲ. The Function……………………………………………………………………127 Section 2 The Brain………………………………………………………………………127 Ⅰ. The External Features of Brain Stem…………………………………………...127 Ⅱ. The Arrangement of the Cranial Nerve Nuclei in Brain Stem………………….130 Ⅲ. The Internal Structure of Medulla Oblongata…………………………………..132 Ⅳ. The Internal Structure of Pons………………………………………………….133 Ⅴ. The Internal Structure of Midbrain……………………………………………..135 Ⅵ. The Reticular Formation in Brain Stem………………………………………...137 Ⅶ. The Cerebellum…………………………………………………………………137 Ⅷ. The Diencephalon………………………………………………………………139 Ⅸ. The Telecephlon………………………………………………………………...142 Section 3 The Conduction Pathway of the Brain and Spinal Cord………………………148 Ⅰ. The Conscious Deep Sensory Pathway…………………………………………149 Ⅱ. The Unconscious Deep Sensory Pathway………………………………………150 Ⅲ. The Superficial Sensory Pathway of the Trunk and Limbs……………………..151 Ⅳ. The Superficial Sensory Pathway of the Head and Face……………………….151 Ⅴ. The Optic (Visual) Pathway………………………………………………….…152 Ⅵ. The Auditory Pathway…………………………………………………………..153 Ⅶ. The Pyranidal System…………………………………………………………..154 Ⅷ. The Extrapyramidal System…………………………………………………….155 Section 4 The Meninges, Blood Vessels of Brain and Spinal Cord, as well as Cerebrospinal Circulation……………………………………………………………………..156 Ⅰ. The Meninges of the Brain and Spinal Cord……………………………………156 Ⅱ. The Blood Vessels of the Brain and Spinal Cord……………………………….159 Ⅲ. The Circulation of Cerebrospinal Fluid………………………………………...161 PART Ⅵ THE ENDOCRINE SYSTEM Ⅰ. The Shape and Location of Thyroid Gland……………………………………..162 Ⅱ. The Shape and Location of Parathyroid Gland…………………………………162 Ⅲ. The Shape and Location of Suprarenal Gland………………………………….162 Ⅳ. The Shape and Location of Hypophysis………………………………………..163 Ⅴ. The Shape and Location of Pineal Body………………………………………..163 Liu Zhi-yu(刘执玉) Introduction Ⅰ. Definition of Anatomy Anatomy is a important fasic medical course which deals with the morphology, structure andfunction of human body. Though the primary concern of anatomy is the morphology and structure of the body, and structure and function should always be considered together. Ⅱ. Classification of Anatomy 1. Gross Anatomy: Systemic Anatomy, Surface Anatomy, and Regional Anatomy. 2. Comparative Anatomy: deals with structure and function related man and animals. 3. Development Anatomy: Study the development of the body from the fertilized age to the maturity. 4. Microscopic and Electro-microscopic Anatomy: Some structure of the body is observed by the microscopy and TEM. Ⅲ. Anatomical Terms 1. Anatomical position Body is standing erect . Face and eyes are directed forward . Hands are by both sides with palms directed forwards . Feet are pointed forwards so that the hells and greater toes together . 2. The terms Anterior-------- front or belly side Posterior-------- back side Superior-------- upper part Inferior-------- lower part Lateral-------- farther midline Medial-------- nearer midline External-------- outer side of body wall or body cavity Internal-------- inner side of body wall Superficial-------- nearer body surface Deep-------- farther body surface Proximal-------- nearer source or attachement of a structure Distal-------- farther source 3. Axes and Planes Sagittal axis: from the anterior to the posterior. Sagittal plane: divides the body into left and right parts. Median plane: a sagittal plane which passes through the body and divides it equal. Coronal axis: from the left to the right, vertical to the sagittal axis. Coronal plane: divides the body into anterior and posterior parts. Vertical axis: from superior to inferior, vertical to the sagittal and coronal axis. Transverse plane: divides body into the superior and inferior parts, at the right angle to both the sagittal and coronal plane. PARTⅠ THE LOCOMOTOR SYSTEM The locomotor system includes the bones, articulations and skeleton muscles. Chapter 1 Osteology Section 1 Introduction Bones in adult are 206 in number, which are divided into 3 parts: the bones of the skull, trunk and extremities. Ⅰ. The General Morphology and Classification of Bones 1. Long bones: a shaft and two ends; tuber-like; medullary cavity; mutrient foramen. 2. Short bones: for example, carpal and tarsal bones. 3. Flat bones: broad and flat, for example, ribs, sternum, scapulae, and many bones of the skull . 4. Irregular bones: varied in shape, include many of the cranial bones, vertebrae, hip bones and so on . Ⅱ. The Structure of bones: Living bones consist of bony substance, periesteum and bony marrow, and with abundant blood vessels and nerves. 1) Bony substance: compact bone and cancellous bone. 2) Bony periesteum: outer layer or fibrous membrane and inner layer or vascular membrane. 3) Bony marrow: red and yellow marrow in different age . Ⅲ.Chemical Composition and Physical Properties 1. Chemical Composition Inorganic Organic Calcium phosphate Calcium carbonate Cells, matrix Collageous fibers 2. Physical properties Inorganic Children Adult Old man 1 2 4 Organic : : : 1 1 1 soft & toughness middle toughness hard & gristle Section 2 The Bones of the Trunk The bones of the trunk include the vertebrae, sternum and the ribs. Ⅰ. The Vertebrae Ⅰ) The Composition of the Vertebral Column Cervical vertebrae 7 Thoracic vertebrae 12 Composition Lumbar vertebrae 5 Sacaral vertebra 1(5) Coccygeal vertebra 1(4) Ⅱ)General Features of A Vertebra Body Pedicles …………………………………………………...2 Laminae……………………………………………………2 Transverse processes ……………………………………...2 Sup. articular process……………………………………...2 Vertebra Arch Inf. articular process……………………………………….2 Spinous process……………………………………………1 Sup. vertebral notch……………………………………….2 Inf. vertebral notch………………………………………...2 Foramen Ⅲ)Regional Differences Vertebra C T L Body …………….more ………..and………… more…………….. massive Foramen larger, triangular smaller, rounder larger, triagular Spinous process short, bifid long slopiny massive square Transverse process short, bifid facet for rib longer Articular facet horizontal coronal sagittal Ⅳ)Specialized Vertebrae 1. The Atlas, First Cervical Vertebra ①No body and two lateral masses, ②Anterior and posterior arch ③A fovea for dens of axis, ④Sulcus for vertebral artery. 2. The Axis, The Second Cervical Vertebra It has a dens, and its ant.articular surface for articulartion with the fovea dentis of atlas. 3. 6th C. vertebra: Coroid tubercle on the transverse processes. 4. 7th C. vertebra: the prominence, spinous process is long, nearly horizontal, and without bifid. Sup. and inf. costal focet on the body 5. Thoracic Ⅴ. Costal facet on the transverse process Spinous process------long and sloping downwards. Base------sacral promontory Anterior surface------ ant .sacral foramen 6. Sacrum Ⅴ. Posterior surface----median sacral crest, sacral hiatus, sacral cornae Lateral----posterior sacral foramen Sacral canal Ⅱ. The Sternum The sternum is a flat bone which lies in the midline of the anterior wall of the thorax. Manubrium------iugular notch Sternum Body------facets for costal cartilages Xiphoid process The sternal angle: The junction of manubrium with the body, which is useful landmark indicates the level of the articulation of the 2nd costal cartilarge with the sternum. According to this landmark the order of the ribs and the intercostal space can be determined. Ⅲ. The Ribs True: 1st ------7th articulate to the sternum 1. Classification False:8-12th, and 8-10th ribs form the arch of rib. Floating: 11-12th ribs. 2. Composition and Features Head Neck Body Anterior end Costal gloove Articular focet on the head Costal tubercle Costal angle 3. First rib is short, sharply curved and flattened. Superior and inferior surface Inner and outer border The rib Scalene tubercle on the superior surface Sulcus of subclavicular a . Sulcus of subclavicular v . Section 3 The skull The skull consists of 23 bones, rests upon the superior end of the vertebral column. The bones are closely fitted together by sutures or cartilages except the mandible and the hyoid. They carry out the function of protection and support of the brain and the organs of sight, hearing and balance. And the upper part of the digestive and respiratory system. It is devided into two parts, the cranial and facial bones. Ⅰ. General View 1. Division of skull 23 bones Cranial portion 8 bones Facial portion 15 bones 2. Bones Cranial Facial Single frontal ethmoid vomer sphenoid hyoid occipital mandible Paired perietal temporal maxilla zygomatic palatine nasal lacrimal inf.nasal conchae 3. The mandible It is the only movable bone in the skull, which consists of a horse shoe-shaped body and two flat rami. The body Alveolar arch on sup. border Mental protuberance Mental foramen Mental spine Base of mandible The rami Coranoid process Condylar process Mandibular notch Mandibular foramen Mandibular canal Angle of mandible 4. The hyoid bone is located between the mandible and the larynx. It consists of a body and two paired projections, the lesser and greater cornua. Ⅱ. The Cranial Cavity The Floor of the cranial cavity has 3 fossa arranged like steps at the different levels. They are the anterior, middle, and posterior cranial fossa. 1. The anterior cranial fossa Composition Orbital part of frontal bone Lesser wing of sphenoid Cribriform plate & crista galli of ethmoid Structure Cribriform plate Crista galli Cribriform foramen 2. The middle cranial fossa is formed by the body and great wing of the sphenoid; the anterior surface of the petrous portion, and the squamous portion of the temporal bone. The Structure of the Middle Cranial Fossa The Middle Optic foramen Ant.clinoid process Sella tubercle Hypophyseal fossa Dorsum sellae Post.clinoid process Trigeminal impression The lateral Sup.orbital fissure (Ⅲ ⅣⅤ1Ⅵ) Carotid sulcus Foramen lacerum Foramen rotundam(Ⅴ2 ) Foramen ovlae (Ⅴ3 ) Foramen spinousum (mid.min.a) Arcuate eminence Roof of tympanic cavity 3. The posterior cranial fossa Formed by the posterior surface of the petrous portion and occipital bone. Foramen magnum Hypoglossal canal (Ⅶ ) Internal occipital protuberance Groove for transverse sinus Jugular foramen (ⅨⅩⅪⅤ) Internal auditory meatus(ⅦⅧ) Ⅲ.The External Aspect of the Base of the Skull It is divided into two portions, the anterior and posterior. The Anterior Structures Alveolar arch Hard palate Incision foramen Greater palatine foramen The Posterior Structures Foramen magnum Occipital condyles Hypoglossal canal Jugular foramen Vomer Posterior nasal aperture Pterygoid plates Lateral pterygoid plates Medial pterygoid plates Pterygoid fossa Outer opening of carotid canal Styloid process Mastoid process Stylomastoid foramen Zygomatic arch Mandibular fossa Foramen lacerum Spinous foramen Oval foramen External occipital protuberance Ⅵ. The Anterior Aspect of the Skull The main structures from superior to the inferior: Forehead, Two orbits, Bony nasal cavities, Bony oris cabities. The Bony Nasal Cavity Anterior nasal aperture ( piriform aperture ) 1. The apertures Posterior nasal aperture ( communicates with nasopharynx ) 2. The walls Superior Cribriform plate ( the roof ) Inferior Medial Hard palate ( the floor ) Nasal septum Lateral 3 conchae and meatus Special notes for the lateral wall ①The spheno-ethmoidal recess is situated between the superior concha and the body of the sphenoid bone. ②The spheno-palatine foramen opens into the pterygopalatine fossa. ③The lower orifice of the naso-lacrimal canal opens into the inferior meatus. 3. The Communications of the Nasal Cavity Piriform foramenFace Posterior nasal aperture Nasopharynx Sphenopalatine foramenPterygopalatine fossa Cribriform foramenAnterior cranial fossa Nasolacrimal cuctOrbital cavity 4. The Paranasal Sinuses The sinuses Frontal sinuses Ethmoidal sinuses Sphenoidal sinuses Maxillary sinuses Open into middle nasal meatus middle and sup. nasal meatus sphenoethmoidal recess middle nasal meatus ( poor drainage ) Ⅴ. The Skull at the Birth 1. The skull is large in proportion to the body 1/4 ( Adult 1/7 ) 2. The facial portion is small to the cranial portion 1/8 ( Adult 1/4 ) 3. The orbits are relatively large. 4. The nasal cavity is small in site. 5. Some bones are rudimentary. 6. The fontanels are unossified between the bones. Section 4 The Bones of the Limbs The appendicular skeleton include the bones of the upper and lower limbs. Ⅰ. Bones of the Upper Limb includes shoulder girdle and bones of the freely movable upper limb. Ⅰ) The Should Cirdle It consist of the scapula and clavicle. 1. The clavicle It is S-shaped, and joins the trunk with the upper limb. The rounded medial end, termed sternal end, termed sternal end, joint the manubrium by sternoclavicular joint. The flattened lateral (or acromial) end articulates with the scapula. 2. The scapula which is a triangular flat bone situated on the thorax. It has three borders, the meadial, lateral and superior borders; Three angles: the superior, inferior and lateral; and two surfaces: the anterior or costal and the posterior or dorsal surfaces. There is a notch on the superior border, termed scapular notch, lateral to this, a thick bent coracoid process projects forward. The lateral angle of the scapula is a thickened one, which has a concave articular surface, the glenoid cavity. There two tubercles above and below the cavity, termed the supraglenoid and infraglenoid tubercles. The inferior angle is lower end of scapula, at the level of the seventh rib, which is a landmark in the back for determination of the order of the ribs. The costal surface is concave know as subscapular fossa. The spine of scapula is a triangular crest on the dorsal surface. The supraspinus fossa and infraspinus fossa are above and below the spine. The acromin is a triangular bony plate, which has an oval small focet for articulation with the clavicle. Ⅱ)The Mobility Skeleton of the Upper Limb 1. The composition The proximal The middle Humerus Radius, ulna 2. The humerus: head of humerus anatomical neck surgical neck greater tubercle lesser tubercle intertubercular sulcus crest of greater tubercle crest of lesser tubercle 3. The radius: head of radius neck of radius shaft of radius ulnar notch 4. The ulna: troclear notch The distal Carpal 8 Metacarpal 5 Phalanges 14 shalft of humerus deltoid tuberosity sulcus for radial n. trochlea of humerus olecranon fossa lateral epicondyle medial epicondyle sulcus of ulnar n. articular circumference tuberosity of radius interosseous border styloid process ( radius ) tuberosity of ulna coronoid process shaft of ulna olecranon articularcircumfrence radial notch styloid process ( ulna ) 5. The bones of the hand: The carpal bones is divided into two groups: The proximal group: scaphoid, lunate, triangular and pisiform bone. The distal group: trapezium, trapczoid, capicate and hamate bone. The metacarpal bones----base, head, shaft. The phalanges----proximal, middle and distal phalanx, tuberosity of phalanges. Ⅱ. Bones of the lower limb includes the pelvic girdle and the bones of the freely movable lower limb: Ⅰ)The Pelvic girdle is formed by two hip bones. The composition of the hip bone which is fused by the ilium, ischium and pubis. The ilium: liliac body, ala, crest, tuberosity anterior superior iliac spine anterior inferior iliac spine posterior superior iliac spine posterior inferior iliac spine iliac fossa, arcuate line. The ischium: ischial tuberosity, ischial spine, ischial body, greater sciatic notch, lesser cciatic notch. The pubis: pubic body, superior ramus of pubis, iliopubic eminence, pubic tubercle, pubic crest, pectum of pubis, symphyseal surface, obturator foramen, pubic arch, subpubic angle ( in man ), acetabular fossa, acetabular notch, lunate surface. Ⅱ ) Mobility Skeleton of Lower Limb which is divided into three parts, the proximal----femur; the middle----bibia, fibula; distal----tarsus( 7 ). 1. The femur: head of femur pectineal line fovea for lig. of head medial condyle neck of femur patellar surface greater trochanter lateral condyle intertrochanteric crest intercondylar fossa intertrochanteric line medial epicondyle shaft of femur lateral epicondyle linea aspera addactor tubercle gluteal tuberosity 2. The tibia: Superior articular surface shaft of tibia medial and lateral condyles interosseous border intercondylar eminence popliteal line articular surface for fibula medial melleolua tuberosity of tibia fibular notch 3. The fibula: head of fibula, neck of fibula, shaft of fibula, tuberosity of fibula, interosseous border, lateral melleolus, articular surface. 4. The patella 5. The tarsus: talus calcaneus navicular and cuboid bone, first second and third cuneforms should be remembered. 6. The metatarsus 5, phalanges 14, the tuberosity of the fifth metatarsus is obvious land mark which can be felt on the living body. Chapter 2 Arthrology Section 1 Introduction The bones are connected together by articulations which are formed by means of fibrous, cartilaginous or osseous tissues at different parts of their surface. Ⅰ. The Classification of Articulation Ⅰ)Inmovable Articulations ( synarthoses ) which include the fibrous joints( membrane ), cartilaginous joints( synchodrosis ) and synosteosis, for example, the suture articulations in the skull and ligament syndesmoses(e.g., the yellow lig. ). Ⅱ)Movable Articulations ( diarthroses, synovial joint ) the bones are connected by the joint capsule and ligament. The joint cavity presents freely movable. Ⅲ)Semisynovial Joint: e.g. Pubic symphysis. Ⅱ. The Structure of the Synovial Joint Ⅰ)The Essential Structure 1. The articular surfaces. Generally there are two articular surfaces in a joint, the articular head and fossa, which are covered by the cartilage. 2. The joint capsule. It enclosed the joint cavity, and consists of the fibrous layer and synovial layer. The synovial layer lies insides of the fibrous capsule, which produces some synovial fluid that lubricates the joint. 3. The joint cavity which is closed by synovial membrane and articular cartilage. Ⅱ)The Accessory Structure 1. The ligament 2. The articular disc 3. The glenoid labrum with bursa Ⅲ)The movement of joint: 1. Gliding or slipping movement 2. Flexion and extension ( Angular movement ) 3. Adduction and abduction 4. Pronation and supination 5. Rotation 6. Circumduction Section 2 The Articulations of Axis Skeleton The 24 pieces of vertebrae, the sacrum and the coccyx are connected together to form the vertebral column which supports the skull and bears the weight of the upper part of the body. And the spinal cord, the spinal nerve roots, and meninges are located in the vertebal canal. Ⅰ. The Joints Between the Vertebra The vertebrae are connected by joints, intervertebral disc and ligaments. Ⅰ)The Articulations Between the Vetebrae Bodies Annulus fibrosus----fibrous loop 1. The Intervertebral Discs Nucleus pulposas----pulpiform nucleas 2. The anterior longitudinal ligament 3. The posterior longitudinal ligament Ⅱ)The Articulations of the Vertebral Arches 1. The joints of articular processes 2. Yellow ligament ( ligamenta flava) 3. Interspinous ligaments and intertransverse ligaments 4. Supraspinous ligaments Ⅲ)The Lumbosacral Joints Ⅳ)The Atlantooccipital Joints Ⅱ. The Vertebral Column and Its Movements Ⅰ)The View From the Lateral Aspect The physiological curves: 1. The thoracic and pelvic carves ( concave ventrally ) as primary carves. 2. The cervical and lumbar curves ( convex forward ), as the secondary curves. Ⅱ)The movements: 1. Flexion and extension 2. Lateral flexion 3. Rotation 4. Circumduction Ⅲ. The Thorax Ⅰ)The shape which is conical in shape, being narrow above and broad below, falttened from before backward. It has the upper opening or thoracic inlet and the lower opening or thoracic outlet. And the inlet is small and the outlet is wide and irregular. 12 thoracic vertebrae Ⅱ)The Composition 12 pairs of ribs with costal cartilages 1 sternum Ⅲ)The Upper Opening ( Thoracic inlet ) is formed by the upper margin of the first vertebra, manubrium and first pair of ribs. Ⅳ)The Lower Opening ( Thoracic outlet ) is bounded by the 12th vertebra, 12th and 11th ribs, costal arch and xiphoid process. Section 3 The Articulations of the Cranial Bones Most of the cranial bones are connected by the sutures and synchondrosis (synostosis ) except hyoid and mandible. Ⅰ . The Temporomandibular Joint It is formed by the head of the mandible with mandibular fossa and the articular tubercle of the temporal bone. The articular capsule is attached to the margins of the circumference at the fossa and the neck of the mandible. The articular cabety is divided into two parts by the disk. Also there is the strong lateral ligament to reinforce the joint. Ⅱ. The Movements of the Temporomandibular Joint. 1. Opening and closing of the mouth 2. Protuusion 2. Retraction 4. Lateral movement of the jaws Usually above movements are conbined in mastication. Section 4 The Articulation of the Appendicular Bones The articulations include all joints of the upper and lower limbs. Ⅰ. The Joints of the Upper Limb Ⅰ)The Articulation of the Girdle of the Upper Limb 1. The Sternoclavicular Joint It is formed by the medial end of the clavicle, the clavicular notch of sternum, and the first costal cartilage. The characteristics of the joint: Its capsule is strong, thick and strengthened by ligaments. The movements of the joint are following: superiorly, inferiorly, anteriorly, posteriorly, in a circumductory path and also rottory. 2. The acromioclavicular joint It is formed by the lateral end of the clavicle and the medial border of the acromion. The movement is gliding. 3. The coracoclavicular ligament. 4. The coracoacromial ligament. Ⅱ)The Articulations of the Free Upper Limb 1. The shoulder joint: which is a typical ball and socket joint between the glenoid cavity of the scapula and the head of the humerus. The shallow glenoid cavity is deeped by the glenoid lip. The joint capsule is a loose cac, thin, especially, lower portion, attached to the margin of the glenoid cavity, also it si attached to the anantomical neck of the humerus. The long head of the biceps brachii arises from the supraglenoid tubercle, passes through the joint cavity. The capsule is strengthened superiorly by the coracohumeral ligament which passes from the base of the coracoid process to the greater tubercle of the humerus. The long head of the biceps brachii arises from the supraglenoid tubercle, passes through the joint cavity. The capsule si strengthened superiorly by the coracohumeral ligament which passes from the base of the coracoid process to the greater tubercle of the humerus. The movements of the shoulder joint: which is the most movable joint in the body: flexion and extension; abduction and adduction; rotation ( medial and lateral ); circumduction. 2. The elbow joint It is a compound joint in one synovial cavity, made up of three articulations as follows: the humero-ulnar joint; the humeral radial joint; the proximal radioulnar joint. The joint capsule is much thin and loose. There are some ligaments, the radial collateral ligament, the ulnar collateral ligament and the annular ligament which strengthen the capsule. The movement of the elbow joint: flexion and extension, pronation and supination. 3. The articulations between radius and ulna: ① the proximal radioulnar joint ② the interosseous membrane ③ the distal radioulnar joint The movements: pronation and supination. 4. The Radiocarpal Joint It is formed by two joint surfaces which are the distal surface of the radial end together with the disc below ulna, and the proximal surfaces of 3 carpal bones, the scaphoid, lunate and triquetral. Ⅱ. The Articulaions of the Lower Limb It includes those of the pelvic girdle, and the free lower limb. Ⅰ)The Articulations of the Girdle of the Lower Limb 1. The composition of the pelvis It is formed by the sacrum, coccyx and two hip bones, and divided into the greater and lesser pelvis by the terminal line. The terminal line----formed by the promontory of the sacrum, anterior border of the sacral ala, arcuate line, pectin pubis, public crest and the upper border of the symphysis pubis. The pelvic inlet is indicated by the terminal line. The pelvic outlet is bounded by the apex of the coccyx, ischial tuberosity, sacrotuberous ligament, pubic arch, lowerborder of the symphysis pubis. 2. The sacro-iliac joint is formed by the articular surfaces of the sacrum and ilium, and strengthened by the ligaments, especially, interosseous sacroiliac ligament. 3. The symphysis pubis There is a interpubic disc in this articulation which is strengthened by the superior pubic ligament and arcuate pubic ligament. 4. Some important ligament of the pelvis The sacrospinous ligament The sacrotuberosity ligament The iliolumbar ligament The obturator membrane Ⅱ)The Articulation of the Free Lower Limb 1. The hip joint is a typical ball and socket joint, formed by the acetabulum of the hip bone and the head of the femur. The capsule is attached to the rim of the acetabulum, intertrochanteric line and crest. The cavity of the joint is deeped by the acetabular lip, and the femoral capitate ligament is in it. The accessory structure of the joint: The acetabular labrum, acetabular ligament, capitate ligment, iliofermoral ligament. The movement of the joint: flexion, and extension, adduction and abduction, medial and lateral rotation, circumduction. 2. The knee joint It is the largest and most complicated joint of the body. It is made up of the articulations between the femoral and tibial condyles, and between the patella and the femur. The capsule is attached to circumference of the articular surfaces. The accessory structures of the joints. The discs: medial and lateral meniscus. In the cavity: the anterior cruciate ligament the posterior cruciate ligament. Around the capsule: the medial ( tibial ) collateral ligament. The lateral (fibular) collateral ligament. The oblique popliteal ligament. The transverse ligament of the knee. The suprapatellar bursa. The synovial folds. The movements: flexion and extension, medial and lateral rotation (in flexion position). 3. The tibio-fibular articulations: There are three articulations in it, the proximal tibiofibular joint; the interosseous membrane; the distal tibiofibular articulation (ligament). 4. The ankle joint: The articular surface of the distal end of the tibia and fibula form a socket which is articulated with trochlea of the talus. The joint capsule is attached to the circumference of the articular surface and strengthened by the ligaments which are the medial (or deltoid) ligament, the anterior talobibular ligament, the posterior talofiburlar ligament and the calcaneofibular ligament. The movements: dorsoflexion and plantal flexion abduction and adduction. 5. The articulation of the foot It includes those of the ankle joint, intertatarsal joints, tarsometatarsal joint, inermetatarsal joints, metatarsophalangeal joint and the interphalangeal joints. 6. The arches of the foot The bone of the foot are arranged in three arches. They are the medial longitudinal arch which is formed by the calcaneus, talus, navicular, cuneiforms, and the first, second, third metatarsals. And the talus is the kty bone in this arch. The lateral longitudinal arch is formed by the calcaneas, cuboid and the lateral two metatarsals. The transverse arch is formed by the cuboid, the three cuneiforms, and the bases of the metatarsal bones. Chapter 3 Myology Section 1 Introduction The muscles may be divided into the three types: the skeletal muscle, smooth muscle and cardiac muscle. Here the skeletal muscle is only discussed, which is a part of the locomotor system. It is called voluntary muscle because its contraction is under the voluntary control. About 40% of the body weight is provided from the skeletal muscle. They produce all the voluntary movements, and are essential to the performance of a great variety of body function. Every piece of the skeletal muscles possesses a definite shape, structure, location and accessory apparatus, also has rich supply of the bolld vessels, lymphatics, and nerves. So that, the natural shape, location and action of the muscles are frequently discussed in this chapter. Ⅰ. The Morphology: Each muscle is composed of the muscular fibres. Generally it can be divided into the belly and tendon, and the later is attached to the bone. The muscles vary extremely in their shape. It may be long, short, broad and circular band-like. In addintion, some muscles have more than one belly or one origin. Some of them, howener, resemblance to feathers, so we called them as pinnate muscles. Ⅱ. The origin and Insertion: the end of fixed attachement of the muscle is called the origin,the movable one the insertion. Most of muscles are attached either derectly or by there tendons to bones, cartilages, ligaments and so on. In the limbs the more distal parts are usually mobile. Therefore, the distal attachement is usually called the insertion. Some proximal end are generally called the origin. Ⅲ. The Action: the students should try to learn the origin and insertion of the major muscleofthe body. These, of necessity, include some knowledge of the joint which muscle passes. So that the action of the muscle can be understand. The basic action of the muscle is the contraction. When the action of the muscle operates over some articulation we can see the group of the muscles to make the movement of the joint. According to the action of the function of the muscles the skeletal muscles can be divided into the following: the prime mover, antagonist, synergist. Which are controlledly the nerves? Ⅳ. The Supplementaty Structrue of Muscles Ⅰ) The Fascia is formed by connective tissue, and divided into the superficial and deep fascia. Ⅱ) The Synovial Bursa is a connective tissue sac with a slippery inner surface, and filled with synovial fluid. The bursa is present near the joint. Ⅲ) The Synovial Tendon Sheath is a double layered synovial sheath, in which the tendon runs, generally locates in the hand and foot. Ⅳ) The Sesamoid Bones which are developed in some tendons near the joint. Section 2 The Muscles of the Trunk The muscles of the trunk may be divided into many groups: Rhe muscles of the back, the muscles of the thorax, the diaphragm, the muscles of the abdomen and the muscles of the perineam. The last one will be discussed in the urigenital system. Ⅰ. The Muscles of the Back. Which are located on the posterior aspect of the trunk, and canbe divided into two groups, the superficial and the deep. The superficial group includes the trapezius, latissimus dorsi, levotor scapulae and rhomboid muscles. The deep group is a complex group of muscles, which is mainly concerned the movement of the vertebral column. Ⅰ) The Trapezius which is a large, triangular muscle. It arises from the superior muchal line,external protuberance of the occipital bone, nuchal ligament, spine of 7th C vertebra, spines and supraspinous ligament of the thorax vertebrae. And it is inserted into the lateral 1/3 of the clavicle, acromion, and the spine of the scapula. Actions ①Steadies, raises, descends, retracts, and rotates the scapula; ②Extends the head; ③Dropping shoulder. Ⅱ) The Latissimus Drsi It is a large wide, triangular muscle, and located the both sides of theback. It arises from the spines of the lower six thoracic vertebrae, the thoracolumbar fascia, lumbar and sacral spinous process, and the iliac crest. And it is inserted into the floor of the intertubercular groove. Actions: Extends, adducts, medially rotates humerus; Elevate the body on the hand. Ⅲ) Sacrospinal Muscle It is located in the vertebral groove on both side of the spine. The Function: Bend and rotate the spinal column by acting on one side; extend the spinal column by acting on both sides. Ⅳ) The others: The levator scapulae, rhomboid muscles, and thoracolumbar fascia Ⅱ. The Muscles of the Neck by their situations they are divided into four groups: the superficial, suprahyoid, infrahyoid and the deep group. Ⅰ) The Superficial Group 1. The platysma is a very thin and located in the superficial fascia of the neck. 2. The sternocleidomastoid muscle It arises from the manubrium and the medial 1/3 of the clavicle, and is inserted into the mastoid process of the temporal bone. The actions: ①The head is inclined laterally and the face is rotated to the opposite. ② Flexthe neck by the acting of both sides. Ⅱ) The Hyoid Muscles 1. The suprahyoid muscles: Digastric muscle, mylohyoid muscle, stylohyoid muscle, geniohyoid muscle. 2. The infrahyoid muscles: The sternohyoid muscle, omohyoid muscle, aternothyroid muscle, theyrohyoid muscle. Ⅲ) The Deep Cervical Muscles The group of these muscles are located in front on both sidesof the cervical vertebral column. They are the scalenus anterior, scalenus medius, scalenus posterior. The scalenus anterior which arises from the transverse process of the cervical vertebra, and isinserted into the first rib. Above the first rib, there is a triangular space, scalene fissure between the anterior and middle scalenus. The brachial plexus and subclavian artery emerge from this space. The action of the scalenus anterior and scalenus medius which elevate the first rib to breath deeply, flex and rotate the cervical vertebral column to the opposite side. Ⅲ. The Muscles of the Thorax which are divided into two groups: the extrinsic and intrinsic muscles. Ⅰ) The extrinsic muscles which include the pectoralis major, pectoralis minor, seratus anterior and subcleivius. 1. The pectoralis major This is large, thick and fan-shaped muscle, covers the upperpart of the chest. It arises from the medial half of the clavicle, the anterior surface of the sternum, the first six costal cartilages, and the aponeurosis of the external oblique mascle of the abdomen. And it is inserted into the crest of the greater tubercle of the humerus. The Actions: ①Flexes, adducts, and rotates the humerus medially; ②Draws the body upward when the arms are fixed, ③Elevates the ribs to help the inspiration when the scapula is fixed. 2. The pectoralis minor is deep to the pectoralis major. 3. The seratus anterior overlies the lateral portion of the thorax.. Ⅱ) The Intrinsic Muscles which are located between the fibs and sternum or vertebrae. The chief muscles of this group are the external and the internal intercostals muscles. 1. The external intercostals muscles which are located intercostals spaces superficially, arise from the lower border of each rib, and are inserted into the upper border of the rib below. 2. The internal intercostals muscles They are lacated in each intercostals space deep to the external intercostalmuscles. Their fibers run obliquely at right angle to those of the external intercostals muscles. The actions: the external intercostals muscles elevate the ribs to help inspiration, and the inernal interrcostal muscles muve the ribs downwards to help expiration. Ⅳ. The Diaphragm It is a dome-shaped septum between the thoracic and abdominal cavity. It is divided into the central tendon and peripheral muscular portion. There are three openings in the diaphragm: ①The aortic hiatus is at the level of the 12th thoracic vertebra, which transmits the abdominal aorta, the thoracic duct and ofthen the azygos vein. ②The esophageal hiatus is at the level of the 10th thoracic vertebra, which transmits the esophagus, vagal trunks. ③The vena caval foramen is at the level of 8th thoracic vertebra, transmits the inferior vena cava. The actions: ①the chiefly a muscle of inspiration, when diaphragm contracts it will descends. The volumn of thoracic cavity is increased to help the inspiration. ②to increase the intra-abdominal pressure. Ⅴ. The Muscles of the Abdomen They lie between the lower margin of the thorax and the pelvis, which are divided into two groups: the anterolateral and posterior groups. Ⅰ)The Aanterolateral Group which forms the anterolateral wall of the abdominal cavity, and consists of three flat muscles: the external oblique, internal oblique, and transverse abdominis; one straplike muscle, the rectus abdominis. 1. The table for 3 flat muscles ext. oblique m. Origin lower 8 ribs int. oblique m. tran. abdominis Thoracolumbar fascia Ant.2/3 of iliac crest Lat. 2/3 of inquinal lig. Direction Downward Upward & forward of fibers forward at the right angle medially to the ext. oblique m. Insertion Iliac crest Linea alba Inquinal lig. Cart. of 7th to 10th ribs Broad aponeurosis Pubic crest Conjoint tendon Spermatic cord Formed Linea alba Conjoint tendon ………. structure Inquinal lig. Cremaster m…………... Sup. inquinal ring Rectus sheath…………. Rectus sheath Lower 6 costal cart. Thoracolumbar fascia Iliac crest Iat. Of inquenal lig 1/3 Horizontally Rectus sheath Conjoint tendon the same 2. The rectus abdominis which lies each side of the linea alba. It arises from the pubic symphysis and the pubic crest, and inserted into the xiphoid process and anterior portion of the costal arch. 3. The actions of the anterolateral muscles: ①Support and protect the viscera. ②Maintain and increase the intra-abdominal pressure. ③The important actions are in respiration, defecation, micturition, parturition, vormiting and cough. Also to help the movement of the column. Ⅱ)The posterior group include the Psoas Major and Quadratus Lumborum. The psoas major will be discussed in the muscles of the lower limb. The guatratus lumborum lies both side of the column. Section 3 The Muscles of the Head The muscles of the head can be divided into the muscles of fasial expression and muscles of mastication. Ⅰ. The muscles of the facial expression which are the epicranial muscles (occipitofrontalis muscle), orbicularis oculi, oricularis oris, baccinator muscles and muscles aroud the nose. Most of them arise from the skull and are inserted into the skin of the face. They pull the skin in various direction to express the emotion. The muscles around the mouth, eyes, nose, and ears are the sphincters and dilators, which close or open the orifices. Ⅱ. The muscles of mastication They pass the base of the skull to the lower jaw. The table for muscles of mastication Masseter Temporalis Origin Zygomatic Arch insertion Ramus&angle of mandible Elevates mandible Action Temporal fossa Corocoid process of mandible Elevates mandible Med. pterygoid Lat. pterygoid Pterygoid process of sphenoid bone Greater wing & ptery goid process of sphenoid bone Neck of mandible Movement of mandible from side to side Angle of mandible Elevate mandible protrude mandible Section 4 The Muscles of the Upper Limb According to different portions the muscles of upper limb are divided into four groups: the muscles of the girdle, the muscles of arm, the muscles of forearm, and the muscles of the hand. Ⅰ. The Muscles of the Shoulder which surround protect and act the shoulder joint. They arise from the shoulder girdle and are inserted into thehumerus. The table for muscles of the shoulder Deltoid Teres major Origin Insertion Action Lat. 1/3 of clavicle Acromian Crest of spine Inf. angle of scapula Deltoid tuberosity of humerus Abductor of hunerus Crest of lesser Tubercle of humerus Laterally rotates and adducts humerus…… And the supraspinous muscle lies in the supraspinous fossa, deep to the trapeius muscle. The infraspinous muscle is in the infraspirnous fossa, and covered by the deltoid and trapezius muscles. The teres minor lies below the infraspinous muscle. Other muscle is the subscapular muscle which is a large, thick triangular lining on the costal surface of the scapula. Ⅱ. The Muscles of the Arm which are divided into the anterior and posterior muscles The table for muscles of the arm GROUP Biceps Brachii ANTERIOR Name Coracobrachialis Brachialis Origin Coracoid process (short head) Supraglenoid tubercle(long head) Coracoid process Lower part of Humerus Insertion Actions Tuberosity of radius Flexes elbow joint Fascia of forearm Supinates forearm Flexes shoulder joint Flexes and adducts the arm Flexes below joint Middle part of humerus Coracoid process tuberosity of ulna POSTERIOR Triceps Bracii Infraglenoid tuberosity of scapula Olecranon of (long head) the ulna The lateral to the groove for radial n.(lat. head) The medial to the groove for radial n. (med. head) Extends the forearm Extends and abducts the shoulder joint Ⅲ. The Muscles of the Forearm which consist of the anterior and posterior groups. Ⅰ)The Anterior Group is located in front and medial side of the forearm, and divided into two layers: the superficial and deep. 1. The superficial layer is consists of 6 muscles which are arranged from the lateral to the medial side: The brachioradialis muscle, pronator teres, flexor carpi radialis muscle, palmaris longus, flexor carpi ulnaris and the flexor digitorum superficialis. The pronator teres It forms the medial borndary of the cuboid fossa, and lacates the front of the proximal portion of the forearm. It arises from the medial enpicondyle of the humerus, and inserted into the middle of the lateral surface of the radius. The actions of the pronator teres: pronates forearm; flexes elbow joint. 2. The deep layer include 3 muscles: the flexor pollicis longus, the flexor digitorum profundus and the pronator quadratus. They are closely to contact the radius, ulna and interossous membrane. Ⅱ)The Posterior Group The muscles of this group can be divided into two layers, the superficial and deep layer. They are lacated on the back of the forearm. The posterior group Superficial layer Extensor carpi radialis longus Extensor carpi radialis brevis Extensor digitorum Extensor carpi ulnaris Deep layer Supinator Abductor pollicis longus Extensor pollicis brevis Extensor pollicis longus Ⅳ. The Muscles of the Hand which include 3 groups as follows: Abductor pollicis brevis 1. The lateral group: Flexor pollicis brevis Oppponeus pollicis Adductor pollicis Lumbrical muscles 2. The intermediate group: Palmar interossei Dorsal interossei Abductor digiti minimis 3. The medial group: hypothenar Flexor digiti minimi brevis Opponeus digiti minimi Section 5 The Muscles of the Lower Limb Which are divided into foru parts: The muscles of the hip, the muscles of the thigh, the muscles of the leg, and the muscles of the foot. Ⅰ. The Muscles of the Hip They are divided into the anterior group and posterior group according to their location. Ⅰ)The Anterior Group 1. The Iliopsoas It is consists of the psoas major and iliac muscle; the psoas major lies lateral to the lumbar region of the vertebral column, iliac fossa and roof of the thigh. It arises from the transverse processes. Vertebral bodies and intervertebral discs of L1 to L5 vertebrae, and inserted into the lesser trochanter of the femur. The iliac muscle lies the lateral side of the psoas major in the iliac fossa. The Actions: Flexes the thigh; rotate the thigh lateally; if the lower limb is fixed it bends the vertebral column forward and flexes the lumbar region laterally. 2. The Tensor Fasciae Latae lies on the lateroanterior sides of the thigh. Ⅱ)The Posterior Group which lies chiefly in the gluteal region, so that they are also called the gluteal muscles. 1. The Gluteus Maximus It is a large, thick muscle which arises from the iliac ala, sacrum and coccyx, and the sacrotuberous ligament. It is inserted into the iliotibial band and the guluteal tuberosity of the femur. The actions: extends the thigh; rotates laterally; and keeps the posture. 2. The Gluteus medius and gluteus minimus They are located deep to the gluteus maximus in order. 3. The Piriformis muscle It lies deep to gluteus medius, and is a landmark muscle. Ⅱ. The Muscles of the Thigh They are divided into three groups: the anterior, posterior and the medial. Ⅰ)The Anterior Group The Satorius and the Quadriceps Femoris are in this group. They extend the knee and help to flex the hip. 1. The Satorius It arises from the anterior superior iliac spine, passes the upper and anterior part of the thigh to the medial side of the knee, and inserted into the medial surface of the upper part of the tibia. The actions: Extends the hip and knee joint, medially rotates the flexed knee. 2. The Qquadriceps Femoris It lies in front of the thigh. It is the largest and most powerful muscle of the body. It is composed of 4 muscles: the rectus muscles, the vastus medialis, the vastus lateralis, and the vastu intermedius. That is to say, these four muscles forms a strong quadriceps femoris which arises from the anteroinferior iliac spine, line aspera, anterior surface of the femur. It is inserted into the tibial tuberosity by the patellar ligament. The actions: Extends the leg, flexes the thigh, act in climbing, running, rising from a sitting position, and walking up and down stairs. Ⅱ)The Medial Group These muscles locate on the medial side of the thigh. They are chiefly adductors of the thigh: The pectineal muscle, adductou longus, gracilis, adductou magnus. The adductor magnus has a insertion on the adductor tubercle above the medial epicondyle of the femur. There is a hiatus between the aponeurotic insertion of the adductor magnus and the femur, which is termed the adductou hiatus. Which allows the femeral vessels passing through it ingo the popliteal fossa. The action of the muscles of the anterior group: adduct, flex, and laterally rotate the thigh. Ⅲ)The Posterior Group In this group there are 3 large muscles on the back of the thigh. Thesemuscles are, as well as, called the hamstring muscles. They are the biceps femoris, the semitendinous muscle, and the semimembranous muscle. The actions: extends the thigh, flexes the leg, rotates the leg when the knee joint is flexed. Ⅲ. The Muscles of the Leg It is divided into 3 groups: Ⅰ)The Anterior Group Which lies in the front of the tibia, fibula and the interosseous membrane. There are 3 muscles in this group. They are the tibialis anterior, the extensors digitorum longus, and the extensor hallucis longus. The tibialis anterior arises from the lateral surface of the tibia, and is inserted the medial cuneisform bone and the base of the first metatarsal bone. It locates on the lateral side of the tibia, and its tendon becomes free in the distal 1/3 of the leg, passes deep to the retinaculum to the medial border of the foot. The action of the anterior group: Dorsiflex the ankle joint, invert the foot, extend the big toe,and extend digitorum longus. Ⅱ)The Lateral Group It lies on the lateral side of the tibia, and consists of two muscles. The table of the lateral group Name Origin Peroneus Longus Lat. Surface of upper part of fibula Peroneus Brevis below insertion of peroneus longus Insertion Action Base of first metatarsal bone and med. cuneiform bone Tuberosity of 5th metatarsal bone Together they plantar-flex the ankle joint Maintain the transverse and lateral longitudinal arches of the foot Ⅲ)The Posterior Group which plantar-flex ankle joint, and is divided into following layers. The Superficial layer The gastrocnemius The soleus The plantaris The Deep layer The flexor digitorum longus The fibialis posterior The flexor hallucis longus 1. The Tibialis posterior lies laterally to the flexor digitorum longus. It arises from the tibia, fibula and posterior surface of the interosseous membrane, and is inserted into the navicular, intermediate and lateral cuneiforms, and the bases of the 2nd, 3rd, 4th, metatarsals. Acitons: flexes the ankle joint, inverted the foot medially. 2. The Triceps surae muscle. It is one of the powerful muscles. It has three heads, the two heads arise from the medial and lateral condyles of the femur respectively, which form the inferolateral and inferomedial bandaries of the popliteal fossa and unite together to form the convex strong muscle as termed gastrocnemius. And another head is the soleus which lies immediately deep to the gastrocnemius, and arises from the upper part of the posterior surface of the tibia and fibula. The gastrocnemius and soleus muscles unite together to become the strongest cal caneal tendon which inserts into the calcaneus bone. The actions: Plantarflex the ankle joint: steadies the leg on the foot during standing; flexs the knee. Ⅳ. The Muscles of the Foot The extensor digitorum brevis on the dorsum, the muscles of the sole are divided into 3 groups as follow: The muscles of the foot The medial The intermediate Abductor hallucis Flexor hallucis brevis Adductor hallucis Flexor digitorum brevis Quadratus plantae Lambricates interosseous m. The lateral Abductor digitiminimi Flexor digitiminimi brevis THE PART Ⅱ SPLANCHNOLOGY Chapter 1 Introduction The splanchnology usually concerns with the study of the viscera. According to the function which they perform, the viscera includes the digestive system, urigenital system and endocrine system. Most organs of these system are located in the thoracic cavity and the abdominal cavity, and some of them are associated with the pleura and peritoneum. In this course, we will discuss the general morphology and structure of the viscera. As well as, some function will be concerned in our lessons. Ⅰ. The Common Used Reference Lines of the Thorax 1. The anterior median line A vertical line through the median of the sternum. 2. The midclacicular line It extends downward vertically from the midpoint of the clavicle and ususlly coincides with mammary line in male. 3. The anterior axillary line A vertical line downward from the anterior axillary fold. 4. The midaxillary line A vertical line midway between anterior and posterior axillary line. 5. The posterior axillary line A vertical line downward from the posterior axillary fold. 6. The scapular line A vertical line through the inferior angle of the scapula. 7. The posterior median line A vertical line through the spines of the thoracic vertebrae. Ⅱ. The Abdominal Regions In order to describe the abdominal regions which contains the viscera. The abdomen is divided into nine regions by four imaginary planes, the upper and lower horizontal plane, and the right and left vertical planes. It is often used in the clinic. The upper horizontal plane passes through the lowest point of the costal arch. And the lower horizontal plane passes both iliac tubercles. The right and left vertical plane across the middle point of the inquinal ligament passing above two horizontal plane at the right angle. In this way the avdomen is divided into following portions. Right The upper row The middle row The lower row hypochondriac lumbar iliac Middle epigastric umbilical hypogastric Left hypochondriac lumbar iliac Chapter 2 The Digestive System The digestive system means study of the alinmetary canal of the organs, which includes the digestive canal and certain accessory organs, such as the lips, cheeks, palate, tongue and the teeth, as well as includes some glands, the salivary glands, liver and pancreas. The alimentary canal is about 9 m long extends from the mouth to the anus. It consists of the following parts: the mouth, the pharynx, the esophagus, the stomach, and the small and large intestines. Section 1 The Oral Cavity The oral cavity can be divided into the vestibule and the oral proper cavity. The vestibule of the mouth is a slit-like space. And the oral cavity proper is vounded by the alveolar arches, the isthmus of fauces, the palate, and the tongue. The isthmus of fauces is the bound of the oral cavity and phyrax between the palatoglossal folds. Ⅰ)The Teeth There are two sets of teeth in man, the deciduous and permanent. The structure of teeth: Which includes the crown, the root, the neck, and the pulp. The vessels and nerves pass the apical foramen at the apex of the teeth root into the pulp. Ⅱ)The Tongue It is divided into three parts: the apex, body and the root. It has a dorsal andinferior surface, on the dorsal surface there is a V-shaped groove termed the sulcus terminalis, which is the boundary between the oral part and the pharyngeal part of the tongue. Also there are four types of papillae on the tongue. They are the vallate papillae, fungiform papillae, filiform papillae and the foliate papillae. There is a lingual frenulum which is a vertical fold of mucous membrane in the midline between the tongue and the floor of the mouth. On the both side of the lower end of the frenulum there is a small elevation, the sublingual papilla, on the surface of which is the orifice of the duct of the submandidubular salivary gland. The Muscles of the tongue The muscles of the tongue are consist of intrinsic and extrinsic muscles. The intrinsic muscles lie entirely in the tongue. And extrinsic muscles are three each side, the hyoglossus, the styloglossus, and the genioglossus. The genioglossus draws the tongue forward and downward, and helping to protrude the tongue. It arises from the middle spine of the mandible, and is inserted into the both sides of the mental line of the tongue. Ⅲ)The Salivary Gland There are 3 parts of the major salivary glands whose ducts open into the mouth. As well as, there are many minor salivary glands in the lips, chee,s, tontue and palate. Table of salivary gland Name Position Orifice Parotid Gland The anteroinferior to the ear The posterior border of masseter The posterior mandibular fossa Submandibular Gland In the upper part of neck, below the floor of the mouth, and deep to the mandibular body Beneath the musous membrane of the floor of the mouth The oral surface of the cheek opposite the crown of the 2nd upper molar tooth The floor of the mouth Sublingual Gland the surface of sublingual fold The Parotid Duct: It is about 5 cm long, passes forwards across the masseter muscle and then turns inwards. It pieces the buccinator muscle and opens upon a small papilla on the oral surface of the cheek opposite the crown of the second upper molar tooth. Section 2 The Pharynx The pharynx is the part of the alimentary canal; it is located behind the masal cavity, the mouth and the larynx. It extends from the base of the skull to the level of 6th cervical vertebra to continue the esophagus. The pharynx may be divided into three parts: the nasal, oral and the laryngeal. 1. The Nasopharynx Anteriorly it communicates with the nasal cavity through two large choanae. The pharyngeal opening of the auditory tube presents on the lateral wall of it. Antero-supero-posteriorly to this opening there is a prominent termed the torus tubarins, behind which lies the slitlike pharyngeal recess. 2. The oropharynx which is the continuous with the mouth through the isthmus of the fauces. The palatine tonsil is located on each side of the oropharynx. And lodged in a tonsillar fossa. 3. The laryngopharynx which communicates above with the oropharynx and below with esophagus. Anteriorly it communicates with the cavity of the larynx through the inlet of the larynx. The piriform fossa lies on each side of the laryngeal orifice. Section 3 The Esophagus The esophagus is a muscular tube, about 25cm long, is continuous from the pharynx to the stomach, it passes down through the lower part of the neck and the superor and posterior parts of the midastinum, pierces the diaphragm at the level of the 10th thoracic vertebra, ends the cardial orifice of the stomach. There are 3 narrow portions for the esophagus: ①at its commencement, 15cm long from theinxisor teeth; ②at the level where the left bronchus crossed, 25cm long from the incisor teeth; ③where it passes through the diaphragm, 46cm long from the incisor teeth. Section 4 The Stomach The stomach is located between the end of the esophagus and the beginning of the small intestine. It lies in the epigastric, unbilical, and the left hypochondriac regions of the abdomen. The shape and the position of stomach are varied from person to person. And the capacity varies with age, being about 30ml at birth, and about 1500ml in the adult. 1. The Features: cardiac, cardiac notch, fundus, body, angular notch, pyloric autrum, pyrorus, pyloric sphincter, greater and lesser curvature, anterior and posterior surface. 2. The stomach bed: are most important, the pancreas, the upper pole of the left kidney, the left supararenal gland, the left crus of the diaphragm, the left colic flecture, the spleen, and the posterior wall of the omental bursa. In fact, the stomach bed is the posterior relation of the stomach. Section 5 The Small Intestine It is a convoluted tube, extending from the pyrorus to the iliocaecal valve, where it joints the large intestine. It is about 6-7m long. The small intestine can be divided into the duodenum, jejunum, and the ileum. Ⅰ. The Duodemum which is the shortest, widest and most fixed part of the small intestine, it hasn’t mesentery, and is only partially covered with peritoneum. The shape of the duodenum like and incomplete cirecle, which encloses the head of the pancreas. It lies entirely above the level of the umbilicus. It begins at the pylorus and end opposite the 2nd lumbar vertebra in the jejunum. And it can be divided into four parts. Ⅰ)The Superior part It begins at the pylorus, and ends the area of the neck of the gallbladder. This part also is called the bulbus duodeni in the clinic. Ⅱ)The Descending Part Its medial side is related to the head of the pancreas and common bile duct. The two ducts come into the midial wall of the descending part of the duodenum, and to form a short, dilated tube which is termed the hepatopancreatic ampulla. Ⅲ)The Horizontal Part which begins at the right side of the lower border of the third lumbar vertebra. The anterinor surface is covered with peritoneum. Ⅳ)The Ascending Part At he level of the upper border of the second lumbar vertebra, where it turns ventrally at the duodenojejunal flexure and is continuous with the jejunum. Its right border attaches the upper part of the root of the mesentery. The terminal part of the duodenum and duodenojejunal flexure are fixed on the posterior wall of the abdominal cabity by suspensory muscle of the duodenum which also is termed the ligament of Treitz. Ⅱ . The Jejunum and Ileum which are continuous with the duodenum from the duodenojejunal flexure to the ileocaecal orifice where it joins the large intestine. The upper 2/5 of this seganent of the small intestine is called the jejunum, and another lower 3/5 is the ileum. The most part of ileum is located in the right lower part of the abdominal cavity. The Comparision of Jejunum and Ileum Jejunum Location Artery Wall LUQ Few arcades More Thicker More plica Redder More villi Absent of a little Ileum RLQ Several arcades Lesser Thinner Fewer plica Grey Lesser villi More lymph tissue Section 6 The Large Intestine The large intestine has a greater caliber. Usually its most part is more fixed on the posterior wall of the abdominal cavity. There are three considerable characteristics, the taeniae coli or longitudinal bands; the haustracoli or sacs; the epiploic appendices or adipose projections. The parts of the large intestine: the caecum, the vermiform appendix, the colon-the ascending, transverse, descending and the sigmoid colon, and the rectum. Ⅰ. The caecum Usually it is located in the rught iliac fossa. The caecum is generally covered completely with peritoneum. There are the ileocaecal valves on the wall of the caecum where the ileum come into to joint the large intestine. Ⅱ. The Vermiform Appendix It is varialble position, and usually it locates in the right iliac fossa. The Projection of the Root of the Appendix which is at the conjuction of the middle 1/3 and the lateral 1/3 of the line which connects the umbilicum and the anterior-superior iliac spine. Ⅲ. The Rectum and Anal Canal which is continuous with the sigmoid colon at the S3. It lies in the pelvic cavity. The Rectum 1. Sacral flexure-downward and backward 2. Perineal fexure-downward and forward 3. Rectal ampulla-dilatation 4. Transverse rectal folds-two on left, one on right. Anal canal 1. Anal columns 5. Anal pectin 2. Anal valves 6. White line 3. Anal sinus 7. Internal anal sphincter 4. Pectinate line 8. External anal sphincter Section 7 The Liver The liver is the largest gland in the body. Ⅰ. The Position: In the right hypochondriac region, the epigastric region, the left hypochondriac region (a little part). Ⅱ. The Lobes: Right lobe-large Left lobe-small Quadrite lobe Caudate lobe-tail lobe Ⅲ. The Features: Wedge-shaped organ Two surfaces: the superior and inferior “H”shaped structure formed by two longitudinal sulci and transverse sulcus Ⅳ. The Ligaments: Falciform lig. Round lig. Right and left triangular lig. Ant. And post. coronary lig. Ⅴ. The Hepatic Porta (Porta Hepatis ) The transevese sulcus is called the hepatic porta. 1. Left and Right hepatic duct 2. Left and Right branches of the proper hepatic A. 3. Left and Right branches of the portal V. 4. Nerves 5. Lumphatics Above structures which are surrounded by the connective tissue called Hapatic pedicle. Ⅵ. The Structure Formed of “H”-shaped Sulcus 1. Left-anteriorly: hepatic round ligament 2. Left-posteriorly: hepatic venous ligament 3. Right-anteriorly: fossa for gallbladder 4. Right-posteriorly: sulus ofr vena cave 5. Transverse sulcus: hepatic porta Ⅶ. The Surface Anatomy The inferior bound of the liver is the same as its lower margin which may be represented by and oblique line beginning the lowest point of the right costal arch at the right midaxillary line, and runs to the left along the costal arch, as far as the tip of 9th costal cartilage, crossing to the top of the left 8th costal cartilage, and ending in the 5th intercostals space at the left midclavicular line. The superior bound of the liver is the same as the dome of the diaphragm, which begins 10th rib at the right midaxillary line, runs to the superior border of 7th rib along the thoracic wall, passing 5th costal cartilage at the midclavicular line, and reach 5th intercostals space to the medial side of the left midclavicular line to unite with the lower margin of the liver. Section 8 The Gallbladder and The Biliary Ducts Ⅰ. The Gallbladder which lies in the fossa for gallbladder on the visceral surface of the liver. Ⅱ. The Features 1. A pear-shaped organ 2. Fundus 3. Body 4. Neck 5. Cystic duct Ⅲ. Biliary Apparatus (bile ducts ) 1. Left and right hepatic duct 2. Common hepatic duct 3. Cystic duct 4. Gallbladder 5. Common bile duct Ⅳ. The Bypass of the Bile From the liver bile is produced by the hepatocytes in the liverbile ductulesright and left hepatic ductcommon hepatic ductcystic ductgallbladdercystic ductcommon bile ductdesending duodenum. Ⅴ. The Special Notes 1. Major duodenal papulla In the medial wall of the descending part of the duodenum the common bile duct contact with the pancreatic duct and unite to form hepatopancreatic ampulla which opens into the descending part of the duodenum on the summit of the Marjou Duodenal Papulla. 2. The sphincter of oddi There is the circular muscle around the lower part of the bile duct, ampulla and terminal part of the main pancreatic duct, which is termed the Sphincter of Oddi (sphincter of hepatopancreatic ampulla ). Section 9 The Pancreas The pancreas is only smaller gland than the liver. It is located the posterior wall of the abdominal cavity at the level of L1, 2, behind the stomach and other many orghns. Ⅰ. The Parts: the head, body, tail. Ⅱ. The Duct: The pancreatic duct joints the common bile duct ot form the hepatopancreatic ampulla and opens into the major duodenal papulla. Ⅲ. The Function The pancreas produce both exocrine and endocrine secretions. The exocrine fluid of pancreas are drain into duodenum by the series bile ducts. The Islets of Langerhans in the pancreas secrete insuline which control blood sugar in the body. Chapter 3 The Respiratory System The respiratory system includes the respiratory tract and lungs. And the respiratory tract composed of the nose, pharynx, larynx, trachea and main bronchi. Section 1 The Nose The nose is not only the first part of the respiratory tract but also an organ of smell and phonation. External nose-apex, dorsum, root, narse. wings Ⅰ. The Nose left and right cavity Nasal cavity nasal septum four walls Roof: nasal bone and ethmoid bone Floor: roof of the mouth Ⅱ. The Walls Medial wall: nasal septum Lateral wall: sup. , mid., jinf., concha, meatus Ⅲ. The Paranasal Sinus: 4 pairs paranasal sinuses. lie in the frontal bone. 1. The Frontal Sinuses open into the middle nasal meatus. lie in the maxillary bone. 2. The Maxillary Sinuses open into the middle nasal meatus. within the ethmoid bone. 3. The Ethmoidal Sinuses ant. mid. groups open into the mid. nasal meatus. post. group opens into the sup. nasal meatus lie in the sphenoid bone. 4. The Sphenoidal Sinuses open into the sphenoethmoidal recess. Section 2 The Pharynx and Larynx The pharynx has already been discussed within the digestive system. The larynx consists of the cartilages, joints, ligament and the muscles. It lies in the neck region in front of the C5,6 vertebrae and the laryngopharynx. Ⅰ. The Position Changes with Age 1. In adult: Above, near the hyoid bone and root of the tongue. Below, at the level of C6 vertebra. 2. In child and female: higher position. Ⅱ. The Laryngeal Prominence-a median elevation The thyroid notch-at the upper border of the thyroid cartilage. Vestibule vestibular folds, slit Intermediate cavity Ⅲ. Cavity of Larynx Of larynx vocal foldes, slit of glottidis Infraglottic cavity Section 3 The Trachea and Bronchi The trachea is located in the midline of the neck and upper thorax, and in front of the esophagus. It extends from the lower border of the cricoid cartilage at the level of 6th cervical vertebra to the level of the sternal angle, where it divides into the right and left main bronchi. In child the trachea is smaller, deeper in position, and more movable than that in adult. Tracheal cartilage Smooth muscle Ⅰ. The Composition of Trachea Connective tissue Mucous membrane 14-16 C-shaped ring of cartilage Right main bronchus: shoter, wider, more vertical Ⅱ. The Bronchi than the left one. Left main bronchus: longer, less vertical. Section 4 The Lungs The lungs are the essential organs of the respiration. There are two lungs within the thoracic cavity. Each lung is situated on the each side of thorax, and separated from each other by the heart, other contents of the mediastinum. Ⅰ. The Features 1. Right lung is shorter, wider than the left. 2. Each lung is conical, has an apex, a base, two surfaces, three borders. 3. Hilus of lung: root of lung-bronchi, pulmonary artery and veins, bronchial vessels, lymphatics and lymph modes. Ⅱ. The Lobes of the Lung Right lung Left lung 1. Horizontal fissure 1. Upper lobe 2. Oblique fissure 2. Lower lobe 3. Superior lobe 3. Lingulum 4. Middle lobe 4. Oblique fissure 5. Inferior lobe The apex of the Lung is 2.5cm above medial 1/3 of the clavicle. Section 5 The Pleura The pleura is thin serous membrane which lies the inner surface of the thorax and the surface of the lungs. Ⅰ. The Parts 1. Visceral pleura: cover the lungs and fissures of lung Costal pleura 2. Parietal pleura Diaphragmatic pleura Mediastinal pleura Cupula of pleura Ⅱ. Pleural Cavity and Recesse 1. Pleural cavity: two cavities separated 2. Costal diaphragmatic recess 3. Costal mediastinal recess Ⅲ. The Projection of Margin of the Lungs and Pleura Midclavicular line Inf. margin of lung 6th costodiaphragmatic line of reflexion of pleura 8th rib rib Midaxillary line Post. median line 8th at the level of spinal process of T10 at the level of spinal rib 10th rib Chapter 4 The Urinary System The urinary system includes two kidneys, two uriters, a urinary bladder and a urethra. Many waste materials which are produced in living body, such as urea and uric acid, excess water and some inorganic salts are excreted by this system. Also it can regulate the composition of the internal environment of the body. Of course, the system is important to remain the water contents, osmotic relations, and acid-base balance, in addition, the kidney has the endocrine function. Section 1 The Kidneys Ⅰ. The Location 1. On the posterior abdominal wall on both side of vertebral column. 2. The distance between the inferior extremities is longer than that of the superior extremities. 3. The superior extremity of the left kidney is at the level of the inferior border of the body of the T11 vertebra, and the inferior extremity of the left kidney is at the level of the body L2 vertebra. 4. The right kidney is lower half vertebra than the left one. 5. The renal hilus is at the level of the first lumbar vertebra. Ⅱ. The Features 1. Bean-shaped 2. Med. and lat. border, ant. and post. surface, sup. and inf. extremity. 3. Renal hilus is on the medial border 4. Renal pedicle (Calyces, Renal A. V. N. L., Adipose tissue) 5. Left kidney is slender, right kidney is shorter and broader. Ⅲ. The Structure 1. Cortex: Renal column 2. Medulla: Renal pyramids, Renal papulla, Foramina of papullae, Minor calyces, Major calyces, Renal pelvis. Ⅳ. The Covering of the Kidneys 1. Fibrous capsule: Connective tissue fibre. 2. Adipose capsule: Adipose tissue layer. 3. Renal fascia: Two thin fascial membrane closely cover the kidney. Section 2 The Ureters The ureters are consist of two hollow muscular tubes which arises from the renal pelvis to the urinary bladder. They are divided into three parts according to their course. Ⅰ. The Parts 1. Abdominal part lies in front of psous muscle and behind the paritonium. At the superior aperture of the lesser pelvis the left ureter passes through the terminal part of the common iliac artery anteriorly, and the right ureter passes through the beginning of the right external iliac artery anteriorly, to continue with the pelvic part. 2. Pelvic part passes downwards along the lateral wall of the lesser pelvis, then turns medially at the level of the ischial spine to the base of the urinary bladder. Here the deferent ducts crosses it anteriorly to its medial side. In the female the pelvic part of ureter turns downwards, forwards and medially. At the level of the ischial spine, 2cm lateral to the cervis of uterus, ti is crossed anteriorly by the uterine vessels. 3. Intramural part passes obliquely through the wall of the urinary bladder, which opens superolateral angle of the trigone of the bladder. Ⅱ. The Constricted Part (Narrow Part): 1. At the junction of the ureter and renal pelvis. 2. At the point where ureter crosses the superior aperture of the lesser pelvis. 3. At the intramural part. Section 3 The Urinary Bladder The urinary bladder is a hollow, muscular organ which stores the urine. It varies in size, shape, position and relations according to the amount of urine that it contains. The volume of urinary bladder is quite difference with the age. Ⅰ. The Feature 1. Four parts: Apex, Base, Body, Neck. 2. Four surfaces: Superior, Right and Left Lateral, Psoterior (Base). Ⅱ. The Trigone of the Bladder It is a smooth triangular area on the base of the bladder. The right and left orifice of ureter are at the each lateral angle of the trigone. The interuteteric ridge is between the right and left orifice of ureter, which is the landmark to find the orifice of the ureter when the inner side of urinary bladder is examined by the cystoscope in the living body. Ⅲ. The Position At birth, the urinary bladder lies at he relatively higher level. Inadult, it is entirely within the lesser pelvis. While it is descended expanding upwards and forwards into the abdominal cavity. In this case, the peritoneum is lifted away from the lower part of the anterior abdominal wall, and the reflection there fore becomes higher. So that the pucture and some operation on the bladder can be performed just above the symphsis pubis without injuring the peritoneum. Section 4 The Urethra The urethra extends from the urinary bladder to the body surface. It is very different in male and female. Ⅰ. The Female: Narrow membrane canal, about 4cm long. External orifice in the vestivule, and at the anterior to the vaginal opening. Ⅱ. The Male: The urethra will be discussed in the male reproductive system. Chapter 5 The Male Reproductive System The male reproductive system includes the internal and external genital organs. The internal genital organs are composed of the testis, ducts and the accessory gland. And the external genital organs consist of the scrotum and penis. Ⅰ. The Internal Genital Organs Ⅰ)The Testis are located in the scrotum. They are paired oval-shaped organs. Each testis has the superior and inferior extremities. The lateral and medial surfaces, and anterior and posterior borders. The anterior border is free, and the posterior border is mesorchial border which is connected with the epididymis and attached by the misorchium. The blood vessels, nerves and the lymphatics pass through this border to enter of leave the testis. Ⅱ)The Series of Duct 1. The Epididymis It lies the superior extremity and the posterolateral surface of the testis. A comma-shaped The head----superior enlarged portion The Features The body----posterior portion The tail----inferior portion 2. The Deferent Ducts It is the continuation of the epididymis duct. It can be divided into four parts: the testicular part, funicular past, inquinal part and the pelvic part. The special notes: The vasectomy is performed at the funicular part. The terminal portion of the deferent duct is dilated, which termed the ampulla of the deferent duct. Here its end is narrow and joins the duct of the seminal vesicle to form the ejaculatory duct. 3. The Urethra From the internal orifice in the urinary bladder to the external opening at the end of the penis. Prostatic part: urinary crest, seminal colliculu. 3 Parts Membranous part: shortest and narrowest part within urogenital diaphragm. Spongy part: bulb of urethral orifice at the internal urethral orifice 3 Narrow Part at the membranous part of urethra at the external urethral orifice at the prostatic part 3 Dilations at the bulb of urethra at the navicular fossa prepubic curvature 2 Curvatures infrapubic curvature Seminal vesicle Ⅲ. The Accessory Glands Prostatic gland Bulbourethral gland 1. The seminal vesicles are located the posterior to the base of the urinary bladder, lateral to the ampulla of deferent duct, in front of the rectum. Its excretory duct joins with terminal part of deferent duct to form the ejaculatory duct. 2. The prostate which lies in the lesser pelvic cavity, below the urinary bladder and around the superior part of the urethra, and is infront of the rectum. The features of prostate: ①Chestnut-shaped ②The base----broad superior extremity. ③The apex----inferior extremity rests on the urogenital diaphragm. ④The prostic sulcus----lies the midline of the posterior surface. ⑤The five lobes----ant. and post. lobes, median lobe, and two lateral lobes. 3. The bulbourethral glands lie in the deep transverse muscle of perineum, and opens into the upper part of the spongy part of the urethra. Chapter 6 The female reproductive system The female reproductive system includes the internal genital organs and the external organs. I. The internal genital organs which lies in the pelvic cavity , and consist of the ovaries, conveying ducts, uterus and vagina. I)The Ovaries 1. The position they lie in the ovarian fossa which is between the bifurcation of the internal and external iliac arteries on the lateral wall of the lesser pelvic cavity. 2. The features: ①Oval-shaped organ ②Med. and lat. surfaces; ant. and post. borders; sup. and inf. extremities. ③Sup extremity is termed the tubal extremity, and inf. one is called the uterine extremity. ④Post. Border is free, and ant. border is attached to the post .surface of the broad ligament by the mesorarium. ⑤The hilus of ovary is at the middle part of the anterior border. ⑥The size and the surface are much different between the childhood and adult. 3. The fixation The ovaries are maintained in the position by the ligaments. ①Suspensory ligament of ovary-ovarian vessels and ovarian plexus of nerves is in it. ②Proper ligament of ovary-rounded cord. II)The Convey Ducts-The Uterine Tubes 1. The position : they are situated on the upper margins of the broad ligament of the uterus, 2. The parts: Infundibulum, ampulla, isthmus, uterine part. III)The Uterus 1. The position It lies in the lesser pelvis between the urinary bladder and the rectum. Anteflexion----The uter has an obtuse angle between its body and cervix. Anteversion----The obtuse angle between the axis of uterus and the vagina 2. The features: In the adults, the uterus is shaped like an inverted pear and flatted from the front to backwords. There are following structures in the uterus: fundus, body, isthmus, cervix, cervical canal, uterine ostium, and lumen. 3. Supports of the uterus ①Muscles of the pelvic floor, neighbouring organs, and connective tissue. ②Broad ligament. ③Round ligament of uterus ④Cardinal ligament ⑤Sacro-uterne ligament. 4. Special notes: The version angle of the uterus refers to the angle with which the cervix meets the vagina. The normal position is titled anteriorly. The Flexion Angle of the uterus refers to the angle with which the body of the uterus meets the cervix. The normal position is titled anteriorly or anteflexed. The structure in broad ligament of the uterus: uterine tube, ovary, proper ligament of ovary, round ligament of uterus, blood vessels,lymphatics and connective tissue. IV)The Vagina 1. Position Anteriorly the bladder urethra Posteriorly the rectum, anal canal 2. Features The upper end of vagina----fornix The posterior of fornix----posterior fornis Special notes The wall of the posterior fornix is only thin wall part of vagina and layer of peritoneum, which is between the fornix and rectouterine pouch, the drainage may be performed through the posterior fornix. II. The External Reproductive Organs 1. Mons pubis----fat pad 2. Labia majora 3. Labia minora 4. Anterior commissure 5. Posterior commissure 6. Clitoris 7. Vaginal orifice 8. Hymen 9. External urethral meatus 10. Vaginal vestibule 11. Greater vestibuler gland Ⅳ. The Mamma in Female 1. The location ①Vertically the anterolateral of thorax,3rd-7th ribs ②Transversely from the parastrnal line to the midaxillary line ③The nipple is on the centre of the mamma and commonly lies at the level of the 4th intercostals space. 2. The features In the young adult female ①Each mamma forms a round eminence lying within the superficial fascia ②The nipple is on the centre of the mamma, which has orifices of 15—20 lactiferous ducts. ③The base of the nipple is encircled by a pigment area of the skin called the areola of mamma. 3. The structures ①Mammary gland and adipose tissue ②Each mammary gland--15-20 lobes→excretery ducts→lactiferous ducts→lactiferous sinus→opens on the nipple. ③The Cooper ligament. V. The Perineum The perineum is the diamond-shaped region of the outlet of the pelvis, which include all soft tissue between the symphysis pubs and the coccyx. The perineum may be divided into the anterior urogenital triangle and the posterior anal triangle. In the clinic the perineum is the soft tissue between the anus and external genital organs. And in the female the region between the vagina and anus is known as the obstetrical perineum. The pelvic diaphragm: the levator ani; coccygeal muscle; and superior and inferior fasciae of the pelvic diaphragm. Chapter 7 The Peritoneum I.The Concept 1. The peritoneum is the serous membrane in the abdominal cavity and partly also in THD pelvic cavity, which lies on the surfaces of the visceral organs and the wall of the abdominal and pelvic cavity. 2. The parietal peritoneum lies on the walls of the abdominal and pelvic cavity. 3. The Visceral peritoneum lies the surface of the visceral organs. 4. The peritoneal cavity: The parietal and visceral layers of the peritoneum are in actual contact continued .The potential space between them is the peritoneal cavity. 5. The communications in the male, the peritoneal cavity is closed. In the female, it communicates with the external indirectely through the uterine tubes, uterus, and vagina. Ⅱ. The Relationship between Viscera and Peritoneum 1. The intraperitoneal viscera 2. The interperitoneal viscera 3. The retroperitoneal viscera such as kidney, ureters, supernal gland , pancreas , middle part of the rectum , the descending and inferior parts of the duodenum. Ⅲ. The Peritoneal Reflections: The lesser omentum and the greater omentum. 1. The lesser omentum extends from the liver to the stomach and the duodenum, which include the hepatogastric ligament and hepatoduodenal ligament. 2. The epiploic foramen lies the posterior to the free margin of the hepatoduodenal ligament. It is only a passage from the epiploic bursa to the peritoneal cavity. 3. The greater omentum is the largest peritoneal fold. It is made up of four layers which extend between the stomach, duodenum and the transverse colon. 4. The gastrocolic ligament extends between the stomach and the transverse colon. 5. Omental barsa is a flattened narrow space behind the lesser omentum and the stomach. IV.The mesenteries it is usually double layers fold of the peritoneum, which fix the organs, such as jejunum, ilium, to the posterior abdominal wall. 1. The mesenterium the root of mesentery is attached to the posterior wall of the abdomen, which is directly obliquely downwards from the duodenojejunal flexure to the upper part of the right sacro-iliac joint. 2. The mesoappendix 3. The mesocolon transversum 4. The mesocolon sigmoideum V.The Ligaments 1. The ligaments of the liver ①Falciform ligament ②Coronary ligament ③Right and left triangular ligament ④Round ligament of the liver ⑤lesser omentum hepatogastric lig hepatoduodenal lig. 2. The ligaments of the stomach ①Gastrohepatic ligament. ②Gastrosplenic ligament ③Gastrocolic ligament ④Gastrophrenic ligament 3. The ligaments of the spleen ①Gastrosplenic ligament ②Lienorenal ligament ③Lienophrenic ligament 4. The structures in the hepatoduodenal lig. ①Hepatic proper artery ②Portal vein ③Bile duct ④Lymph vessels and nodes ⑤Hepatic plexus of nerves VI.The Pouches and Recesses 1. The pouches in the lesser pelvis, the peritoneum drips downwards to from the large fossa termed the pouch. In the male, the rectovesical pouch lies between the rectum and urinary bladder. In the female, the rectouterine pouch is located between the rectum and the uterine, and the vesicouterine pouch is formed between the anteroinferior surface of the uterus and the posterior surface of the urinary bladder. 2. The Recesses: Duodenojejunal recesses, retrocaecal recesses, and the intersigmoid recess. (Liu zhi-yu) PART Ⅲ ANGIOLOGY Angiology comprises the cardiovascular system and the lymphatic system. Chapter 1 The Cardiovascular System Section 1 Introduction Ⅰ. Composition Ⅰ)Heart: a pump to maintain the flow of blood Ⅱ)Arteries: carrying blood away from the heart to various body tissues Ⅲ)Veins: carrying blood from capillary networks back to the heart. Ⅳ)Capillaries: simply thin endothelial tubes with an enclosed basement membrane (exchange vessels) Ⅱ. The Cardiovascular Circuits Ⅰ)Systems or Greater Circulation Left ventricle→aorta and its branches→capillaries of the body (air and material exchange) →venules→veins→superior and inferior vena cava→right atrium. Ⅱ)Pulmonary or Lesser Circulation Right ventricle→pulmonary trunk and its branches→capillaries of the lung (air exchange)→ pulmonary veins→left atrium. Section 2 The Heart Ⅰ. Position of the heart Ⅰ)It lies in the middle mediastinum within the thoracic cavity, and is enclosed by the pericardium. Ⅱ)It is anterior to the thoracic vertebra 5 to 8, and posterior to the sternal body and costal cartilage 2 to 6. Ⅲ)Two-thirds of it lies on the left of the median line and one-third on the right. Ⅱ. External Morphology of the Heart The heart is a hollow, mascular organ of a somewhat conical form and has an apex, a base, two surfaces, three borders, and three grooves. Base: faces backwards, upwards and to the right. It is formed mainly by the left atrium, and, to a small extent, by the right atrium. Apex: formed by the left ventricle, is directed downwards, forwards, and to the left, It is situated in the 5th left intercostals space, 1-2cm medical to the left mid-clavicular plane (apex beat place). Sternocostal surface (anterior surface): faces forwards and upwards, are formed mainly by the right atrium and the right ventricle, and a lesser portion of its left is formed by the left auricle and the left ventricle. Diaphragmatic surface (inferior surface): is directed downwards and backwards, is formed by the left ventricle and the right ventricle. Right border: formed by the right atrium. Left border: formed chiefly by the left ventricle, and by the left auricle. Inferior border: formed by the right ventricle and cardiac apex, is nearly horizontal. Coronary groove: it separats the atria from the ventricle. Anterior interventricular groove: on the sternocostal surface. Posterior interventricular groove: on the diaphragmatic surface. The anterior and posterior interventricular grooves mark the line of separation between the ventricles, and intersect at apical cardiac notch. Atrioventricular crux is the intersecting point between the coronary groove and the posterior interventricular groove. Ⅲ. Internal Morphology of the Heart (Cavities of the Heart) Ⅰ)Right Atrium 1. Two portions: Proper atrium (anterior portion) divided by terminal sulcus Sinus of vena cava (posterior portion) 2. Three inlets: Orifice of the superior vena cava Orifice of the inferior vena cava (Valve of the inferior vena cava) Orifice of the coronary sinus (Valve of the coronary sinus) 3. One outlet: Right atrioventricular orifice 4. Right auricle is a triangular process towards the left. Terminal crest is a longitudinal muscular ridge and opposite to terminal sulcus. Pectinate muscles are formed by many parallel muscular ridges. 5. Interatrial septum: oval fossa is on its lower part. Ⅱ)Right Ventricle It can be separated into two parts, inflowing tract and outflowing tract, by the supraventricular crest. 1. Inflowing tract: 1) One inlet: right atrioventricular orifice (tricuspid valve). 2) Tricuspid valve (anterior, posterior and septal) →chordae tendineae→papillary m. 3) Trabeculae carneae: Septomarginal trabecula is a muscular band which extends from the ventricilar septum septum to the base of the anterior papillary m. 2. Outflowing tract: 1) One outlet: Pulmonary orifice (pulmonary valve: three semilunar valve, nodules of the semilunar valve) 2) Outflowing tract→arterial cone→pulmonary orifice→pulmonary trunk. Ⅲ)Left Atrium 1. Four inlets: The opening of the right and left pulmonary veins. 2. One outlets: Left atrioventricular orifice. 3. Left auricle: projecting forwards. Ⅳ)Left Ventricle It can be separated into two parts, inflowing tract and outflowing tract, by the anterior cusp of mitral valve. 1. Inflowing tract: 1) One inlet: left atrioventricular orifice (mitral valve) 2) Mitral valve(anterior and posterior) →tendinous cord→papillary m. 2. Outflowing tract: 1) One outlet: aortic orifice (aortic valve) 2) Outflowing tract: aortic vestibule→aortic orifice→aorta 3) Aortic sinuses: are three slight dilatations (right, left and posterior) between aortic cusps and aortic wall, from two of which the coronary arteries arise. Ⅳ. Structure of the Heart Ⅰ)Cardiac wall: comprises three layers, named from within outwards endocardium, myocardium and epicardium. Ⅱ)Intreratial Septum and Interventricular Septum 1. Interatrial septum: slops obliquely, and divides the left and right atrium. 2. Interventricular septum: is placed obliquely. muscular part: a greater portion membranous part: a lesser portion 3. The skeleton of the heart (or the support framework of fibrous tissue of the heart); is composed of fibrous rings and fibrous trigones (left and right). Ⅴ.The Conducting system of the Heart Ⅰ)Function 1. Initiating and conducting electrical impulse. 2. Maintaining the normal cardiac rhythm. 3. Ensuring the proper coordination of the atrial and ventricular contractions. Ⅱ)Composition 1. Sinonatrial node(SA node) It initiates each cardiac cycle. It is situated at the junction between the right atrium and the superior vena cava. It is covered only with the epicardium and commonly called the pacemaker. 2. Atrioventricular node (AV node) It passes sinoatrial impulse towards the ventricles, and it lies on the right side and lower part of the interatrial septum , under the endocardium, just anterosuperior to the orifice of coronary sinus. 3. Atrioventricular bundle (His bundle) From atrioventricular node, it extends through the right fibrous trigone to the posterior margin of membranous part of the interventricular septum, and then turns forwards, at the superior margin of the muscular part, it divides into the right and left limbs. 4. Right and left limbs They passes towards the apex immediately beneath the endocardium of each surface of the interventricular septum respectively. The left limb consists of two main strands, an anterior and a posterior. 5. Purkinje fibres The limbs ramify a number of branches, the terminal conducting fibres or Purkinje fibres are continuous with the cardiac muscle fibres. Ⅵ. The Vessels of the Heart Ⅰ)Arteries 1. Right coronary artery. It arises from the right aortic sinus, and passes between the root of the pulmonary trunk and the right auricle to the coronary groove. Following the sulcus, it runs to the diaphragmatic surface. At the atrioventricular crux, it divides into two branches---posterior interventricular branch and posterior branch of left ventricle. The right coronary artery supplies the right atrium, right ventricle, posterior 1/3 of the interventricular septum, posterior wall of the left ventricle, the sinoatrial node and the atrioventricular node. 2. Left coronary. It arises from the left aortic sinus, and passes forwards between the root of the pulmonary trunk and the left auricle to reach coronary groove, where it gives off the following branches. 1) Anterior interventricular branch It descends along the anterior interentricular groove, and supplies anterior wall of the left ventricle, lesser portion of the anterior wall of the right ventricle, and anterior 2/3 of the interventricular septum. 2) Circumflex branch It passes to the left in the coronary groove and supplies to the diaphragmatic surface of the left ventricle and the wall of the left atrium. Ⅱ)Veins 1. Smallest cardiac veins: end directly into the cardiac cavities. 2. Anterior cardiac veins: open directly into the right atrium. 3. Coronary sinus It situated in the posterior part of coronary sulcus between the left atrium and left ventricle, and opens into right atrium. Its tributaries are: 1) Great cardiac vein 2) Middle cardiac vein 3) Small cardiac vein Ⅶ. Pericardium It comprises two sacs, named the fibrous pericardium and serous pericardium. Ⅰ)Fibrous pericardium It is continuous with the external coats of the great vessels, while its base is attached to the central tendon of the diaphragm. Ⅱ)Serous Pericardium It consists of a visceral layer covering the heart and a parietal layer lining the fibrous pericardium. Between two layers, the potential space called pericardial cavity exists. 1. Transverse sinus: lies behind the commencement of the aorta and pulmonary, in front of superior vena cava and left atrium. 2. Oblique sinus: lies between the posterior wall of the left atrium, left and right pulmonary veins, inferior vena cava and posterior wall of the pericardium. Section 3 The Arteries Ⅰ. Arteries of Pulmonary Circulation Ⅰ)Pulmonary Trunk It arises from the right ventricle, at first in front of the ascending aorta, and turns upwards, backwards and to its left side. In the concavity of the aortic arch, it divides into right and left pulmonary arteries. Ⅱ)Pulmonary Arteries The right pulmonary artery is slightly longer and larger than the left pulmonary artery. They run horizontally to the hilus of the right and left lung respectively. Ⅲ)Arterial Ligament It is a fibrous cord connecting the beginning of the left pulmonary artery with the concavity of the aortic arch. Ⅱ. Arterial of Systemic Circulation ascending aorta Aorta--------------------------------------------------------------------------the right second sternocostal (passing to right, and left arise from upwards ventricle forwards) aortic arch thoracic aorta Joint---------------------------------------the left side of T4 vertebra-------------------------------------- (arching to the left and backwards) (descending along vertebral column) Abdominal aorta At anterior to T12 vertebra-----------------------------------------------------at the lower border of L4 (passing through the aortic hiatus of diaphragm into abdominal cavity) left common iliac artery Vertebra---- right common iliac artery Ⅰ)Ascending Aorta: it arises from the left ventricle at the level of the 3rd intercostals space and behind the left margin of sternum, to reach the 2nd right sternocostal joint. It send out to branches called right and left coronary arteries. Ⅱ)Aortic Arch: it is from the 2nd right sternocostal joint to the inferior border of T4 vertebra. From right and left, three branches are given off from the convex aspect of aortic arch---brachiocephalic truck, the left common carotid artery and the left subclavian artery. The brachiocephalic trunk divides into the right common carotid and right subclavian arteries at the level of the right sternoclavian joint. 1. Common carotid artery The left one springs from the aortic arch, while the right one arises from the brachiocephalic trunk. Each passes upwards behind the sternoclavicular joint, then along the lateral to the trachea and esophagus, at the level of the upper border of the thyroid cartilage, it divides into the external and internal carotid arteries. Carotid sinus: is a dilatation of the terminal part of the common carotid artery and the beginning part of the internal carotid artery. It acts as a pressure-receptor for regulating arterial blood pressure. Carotid glomus: is behind the point of division of the common carotid artery. It acts as a chemoreceptor for regulating the oxygen-carbon dioxide ratio. 1) External carotid artery: Its main branches are as follows: ①Superior thyroid artery→supplying the upper part of thyroid gkand and larynx. ②Lingual artery→supplying tongue, palatine tonsil and sublingual gland. ③Facial artery→supplying submandibular gland, the structures of face, and palatine tonsil. ④Superficial temporal artery→supplying the soft tissue of frontal, temporal and parietal regions, parotid gland, orbicular muscle of eye. ⑤Maxillary artery→supplying external auditory canal, middle ear, meninges, cheek, palatine tonsil, lower and upper teeth and gums, muscles of mastication, nasal cavity, and palate. 2) Internal carotid artery: It ascends to the base of skull and enters the cranial cavity without giving off branches in the neck. This is the major artery to the brain and orbital structures. 2. Subclavian artery The left one springs from aortic arch; the right, from brachiocephalic trunk. At the outer border of the first rib, it becomes the axillary artery. Its important branches are as following. 1) Vertebral artery→supplying the brain and spinal cord. 2) Internal thoracic artery→supplying anterior thoracic wall, pericardium, diaphragm, and upper abdominal wall. 3) Thyrocervical trunk→Its one important branches is inferior thyroid artery, which supplies thyroid gland. 3. The arteries of upper limb Outer border of the first rib thoracoacromial a. axillary a. lower border of teres major m. branchial a. the neck of radial bone lateral thoracic a. subscapular a. thoracodorsal a. circumflex scapular a. posterior circumflex humeral a. ----------profound brachial a. principal a. of thumb ------radial a. -----ulnar a. superficial palmar branch terminal branch deep palmar arch common interosseous a. superficial deep palmar branch palmar arch terminal branch Ⅲ)Toracic Aorta It descends from the lower border of T4 vertebra to the lower border of T12 vertebra, where it passes though the aortic hiatus of the diaphragm and becomes the abdominal aorta. Its branches are: posterior intercostals a.(9 pairs) parietal branches visceral branches -to 3-11 intercostal space and upper part of abdominal wall subcostal a.-abdominal wall. bronchial a. esophageal a. pericardial a. Ⅳ)Abdominal Aorta It continuous with thoracic aortic hiatus of the diaphragm and ends in fronts of L4 vertebra by dividing into the left and right common illac a. The branches are as following: inferior phrenic a. Parietal branches lumbar a. middle suprarenal a. paired renal a. testicular a.(ovarian a.) visceral branches celiac trunk single superior mesenteric a. inferior mesenteric a. 1. Celiac trunk It is a short trunk just below the aortic hiatus of the diaphragm or approximately at the level of t12 vertenra. Left gastric a. esophageal branchabdominal part of esophagus. gastriccardiac orifice and lesser curvature of stomach. anastomosing proper hepatic a. common hepatic a. Ganstroduodenal a. right gastic a. lesser curvature of stomach. left hepatc a. right hepatic a. custic a. gallbladder superior pancreaticoduodenal a. pancreas, duodenum. right gastroepiploic a. greater curvature Of stomach, greater omentum. Anastomosing Left gastroepiploic a. greater curvature of stomach, greater omentum. splenic a. short gastric a. fundus of stomach pancreatic branchbody of and tail of pancreas splenic branchspleen 2. Superior mesenteric a. It is about at the level of L1 vertebra, and passes obliquely between the head of pancreas and the horizontal part of duodenum, and enters the root of the mesentery to reach the right iliac fossa. jejunal and ileal a. jejunum and ileum. to ascending colon, cecum, terminal part of ileum ileocolic a. appendicular a. appendix. right colic a. ascending colon middle colic a. transverse colon 3. Inferior mesenteric a. It is opposite L3 vertebra, passes downwards and to the left to reach the left iliac fossa, then terminates as superior rectal a. left colic a. descending colon sigmoid a. sigmoid colon superior rectal a. rectum Ⅴ)Common Iliac Arterty The common of iliac artery diverge from the abdominal aorta opposite L4 vertebra. Each artery passes downwards and laterally, and ends at the level of the sacroiliac joint by dividing the external and internal iliac arteries. 1. Internal iliac artery obturator a. adductor m. and hip joint parietal branches superior gluteal a. gluteal m. and hip joint inferior gluteal a. umbilical a. superior vesical a.--urinary bladder inferior vesicle a.urinary bladder, prostate, seminal, vesicle, vagina visceral branches inferior rectal a. rectum uterine a. uterus, uterine tube, ovary and vagina internal pudendal a. anal region perineum and external genital organs. Relation between uterine a. and ureter: The uterine a. runs downwards along the lateral wall of pelvis, and turns medially in the broad lig. Towards the cervix of uterus, about 2 cm from the cervix it crosses above and in front of the ureter. 2. External iliac artery Each runs downwards along the medial border of psoas major m. and enters the thigh behind the inguinal ligament to become the femoral artery. One branches of it is called interior epigastric a. which anastomoses with superior epigastric a. behind rectal abdominal m. cends vertically to end the right atrium at the level of the 3th right sternocostal joint. 3.The arteries of lower limb behind midpoint lateral circumflex femoral a. of inguinal lig. adductor hiatus lower border of popliteal m. femoral a. deep femoral a. ↓ articulating popliteal a. branch muscular branch m. of thigh and knee joint medial circumflex femoral a. m. of thigh and hip joint perforating a. m. of thigh femur -posterior tibial a. peroneal a. m. of leg, tibia and fibula -anterior tibial a. dorsal pedal a. Section 4 The Veins ⅠVeins of Pulmonary Circulation Pulmonary veins are four in number, two from each lung, a superior an an inferior. They return the oxygenated blood from the lungs to the left atrium of the heart. Ⅱ. Veins of Systemic Circulation They may be arranged into three groups. superior vena cava system inferior vena cava system(portal venous system) cardiac venous system Ⅰ)Superior Vena Cava System The system is composed by the superior vena cava and its tributaries which collect the blood from the head and neck, the upper limb, the wall and some organs of the thorax, and the upper part of abdominal wall. 1. Superior vena cava It is formed by the junction of right and left brachiocephalic veins just behind the first right costal cartilage close to the sternum, and des 缺 2. Brachiocephalic (lnnominate) veins It is formed, behind the sternoclavicular joint, by the union of the internal jugular and subclavian veins of its side. The angle of the union is termed the venous angle. 1) Internal jugular vein It originates from the jugular foramen, and unites with the subclavian vein to form the brachiocephalic vein. The chief extracranial tributaries are: ① Facial vein ②Retromandibular vein ophthalmic v. facial v. ↑ ↓ cavernous sinus ↑ internal jugular v. ↓ pterygoid plexus ↓ anterior maxillary v. retromandibular v. branch superficial temporal v. posterior branch posterior external subclavian v. auricular v. occipital v. jugular v. or venous angle 2) Subclavian vein It begins at the out border of the first rib and ends behind the sternoclavicular joint. External jugular v. is the major tributary of subclavian v. and passes downwards and backwards on the surface of the sternocleidomastiod m. to end in the subclavian v. 3) The vein of the upper limb They are divided into two sets, superficial and deep, and rich in valves. ① The superficial veins Dorsal digital v. dorsal metacarpal v. dorsal venous network: The radial part of dorsal venous networkcephalic v. the front of radial side of forearm, and elbowouter border of biceps m. goove between deltoid and pectoralis major m. pierces deep fasciaaxillary v.(or subclavian v.) The ulnar part of dorsal venous networksbasilic v. the ulnar side of forearmmedial to biceps m. a little below midpoint of armperforates deep fasciabrachial v.(or axillary v.) Median cubital v. lying on the cubital fossa, running obliquely between the cephalic and basilica v. ②The deep veins With the exception of the axillary vein, they are generally arranged in pairs, flanking the corresponding arteries. 3. Azygos vein It begins as the continuation of right ascending lumbar vein. It ascends along the right side of the thoracic vertebra to the level of T4 vertebra, where it arches forwards over the root of the right lung to end in the superior vena cava. It receives the blood from posterior intercostals v. of the right side, esophageal v. bronchial v. hemiazygos v. Ⅱ)Inferior Vena Cava System The system is composed by the inferior vena cava and its tributaries, which collect the blood from the abdominal and pelvic part, as well as the lower limbs. 1. Inferior vena cava It is formed by the junction of the two common iliac veins anterior to L5vertebra, a little to the right. It ascends on the right side of abdominal aorta, passes in the groove for inferior vena cava of liver, through the vena caval opening of the diaphragm, to reach the thoracic cavity and open into the right atrium. 2. Common iliac vein It is formed by the union of the external and internal iliac veins in front of the sacroiliac joint, and by uniting with opposite one to form the inferior vena cava at the level of L5 vertebra. 1) Internal iliac vein The tributaries of the internal iliac vein can be divided into two sets. parietal tributaries inferior rectal v. visceral tributaries interior pudendal v. uterine v. 2) External iliac vein It is the upward continuation of the femoral vein, begins behind the inguinal ligament. 3) The veins of the lower limb They can be subdivided into two sets, superficial and deep, like those of the upper limb. Both sets are provided with valves. ① The superficial veins Dorsal digital v. dorsal metatarsal v. dorsal venous arch Lateral margin of dorsal venous archsmall saphenous v. behind the lateral malleolusthe midline of the back of legbetween the two heads of gastrocnemius m. popliteal fossaperforates the deep fasciapopliteal v. Medial margin of dorsal venous archgreat saphenous v. in front of the medial malleolushe medical side of leg and knee jointbehind the medial condyle of femurthe medial side of thighsaphenous opening(at about 3-4 cm inferolateral to the pubic tubercle) perforating deep fasciafemoral v. The five tributaries of great saphenous v. are as following: superficial lateral femoral v. superficial medial femoral v. external pudendal v. superficial epigastric v. superficial circumflex iliac v. ② The deep veins of the lower limb They accompany the arteries and their branches, and are similarly named. 3. The tributaries of the inferior vena cava They are also divided into parietal and visceral. Parietal tributaries inferior phrenic v. right lumbar v. (4 pairs) ascending lumbar v left visceral tributaries testicular v. lefteft renal v. (ovarian v.) rightinferior vena cava renal v. leftleft renal v. suprarenal v. rightinferior vena cava hepatic v. : right, middle, left 4. Portal vein It is formed by the junction of the superior mesenteric and splenic veins, behind the beck of the pancreas. It passes upwards and to the right to enter hepatoduodenal ligament, behind the common bile duct and proper hepatic artery to reach the porta of liver, where it divides right and left branches to enter the liver. In the liver this vein ramifies like an artery and ends in capillary-like vessels termed sinusoids. It collects the blood from abdominal part of esophagus, stomach, small intestine, large intestine9with the exception of the lower part of the anal canal), and from pancreas, gallbladder, spleen. 1) The major tributaries of the portal vein superior mesenteric v. portal v. splenic v. superior mesenteric v. inferior mesenteric v. splenic v. left gastric v. right gastric v. portal v. cystic v. paraumbilical v. 2) The anastomoses between the portal venous system and the vena caval system They may collectively offer an effective collateral circulation in case of obstruction of the portal vein. ①Esophageal venous plexus: at the junction of the esophagus and stomach. Portal v. left gastric v. esophageal venous plexusesophageal v. azygos v. superior vena cava. ②Rectal venous plexus: at the ano-rectal junction Portal v. splenic v. inferior mesenteric v. superior rectal v. rectal venous plexusinferior rectal and anal v. internal iliac v. common iliac v. inferior vena cava. ③Periumbilical venous network: at the umbilicus. Portal v. paraumbilical v. periumbilibal venous networkssuperficial epigastric v. great saphenous v. femoral v. external iliac v. common iliac v. inferior vena cava. thoracoepigastric v. lateral thoracic v. xillary v. subclavian v. brachiocephalic v. superior vena cava. superior epigastric v. nternal thoracic v. brachiocephalic v. superior vena cava. inferior epigastric v. external iliac v. common iliac v. inferior vena cava. ④At the posterior abdominal wall: the small tributaries of the inferior and superior mesenteric v. anastomoses with the tributaries of the vena cava, such as the lower posterior intercostals v. inferior phrenic v. lumbar v. renal v. testicular9ovarian) v. Chapter 2 The Lymphatic System Section 1 Introduction Ⅰ. Composition lymphatic vessels lymphatic organs lymphatic tissue lymph capillaries lymph vessels lymphatic trunk lymphatic duct lymph node spleen thymus tonsil and lymph nodules in alimentary canal and respiratory tract. Ⅱ. Charactor Ⅰ)Lymphatic vessel 1. Lymph capillaries They are present in almost all tissues of the body but the brain, spinal cord, epidermis, cornea, lens, enamel, cartilages, et al. 2. Lymph vessels They are rich in valves which give them a characteristic beaded appearance, and arranged in superficial and deep sets. 3. Lymphatic trunks The lymph vessels unite one another to form nine lymphatic trunks, they are: right and left jugular trunks right and left subclavian trunks right and left bronchomediastinal trunks right and left lumbar trunks intestinal trunks 4. Lymphatic ducts The right lymphatic duct and thoracic duct are formed by nine lymphtic trunks respectively. Ⅱ) Lymphatic organs Lymph nodes are small, oval bodies, situated in the course of lymph vessels so that the lymph passes through them on its way to blood. The afferent lymph vessels enter the nodes on its convex surface. The efferent lymph vessels leave the nodes on its concave surface called the hilus. Lymph from some organ or area of the body is drained into the local corresponding lymph nodes, which are termed termed regional lymph nodes for this organ or area. Ⅲ)Lymphatic tissue They are widespread in the wall of the alimentary canal and respiratory tract, and can be called subepithelial lymphatic tissue. Section 2 The Lymphatic Ducts of the Body Ⅰ. Thoracic Duct Right and left lumbar trunks anterior to -----------------------------------chyle cistern--------------L1 vertebra Intestinal trunk Aortic hiatus of diaphragmthoracic cavityright and anterior to T5 thoracic inlet vertebral column --------------inclining to the left-----------------root of vertebral left subclavian trunk neck-----------------------------------left venous angle left bronchomediastinal trunk left jugular trunk The thoracic duct receives lymph from the lower limbs, the abdominopelvic part(wall and viscera), left lung, left half of the heart, left half of thoracic wall, left upper limb, and left half of the head and neck. Ⅱ. Right Lymphatic Duct right subclavian trunk right jugular trunk right venous angle right bronchomediastinal trunk The right lymphatic duct receives lymph from right upper limb, right half of the head and neck, right lung, right half of the heart, right half of thoracic wall, superior surface of right lobe of liver, and part of diaphragm. Section 3 The Lymph Vessels and Nodes of the Body Ⅰ. The Lymph vessels and Nodes of the Head Neck Ⅰ) Lymph Nodes of the Head They lie at the junction between the head and neck, and are arranged in a circle from posterior to anterior, which are occipital, mastoid, parotid, submandibular, submental lymph nodes. Submandibular lymph nodes: lie in the submandibular triangle or near submandibular gland, receive the lymph vessels from the face and mouth; their efferents pass to lateral cervical lymph nodes. Ⅱ) Lymph Nodes of the Neck They include anterior and lateral cervical lymph nodes, the latter comprises two groups. 1. Superficial lateral cervical lymph nodes They are placed along the external jugular vein superficial to sternocleidomastoid m. they receive lymph vessels from the neck and mastoid lymph nodes, and their efferents reach the deep lateral cervical lymph nodes. 2. Deep lateral cervical lymph nodes They lie along the internal jugular vein from the base of the skull to the root of the neck. upper group: retropharyngeal lymph nodes behind the nasopharynx. lower group: supraclavicular lymph nodes along subclavian a. and branchial plexus. They receive the lymph vessels from the head and neck, the tongue, larynx, cervical part of esophagus and trachea, thyroid gland, upper part of thoracic wall and breast; their efferents form the jugular trunk. Ⅱ. The Lymph Vessels and Nodes of the Upper Limb Ⅰ)Cubital (Supratrochlear) Lymph Nodes Which are superficial to deep fascia above the medial epicondyle of the humerus. Ⅱ)Axillary Lymph Nodes They lie in the axillary fossa, and may be divided into five groups. 1. Lateral lymph nodes: arranged along the axillary vessels, and receive the superficial and deep lymph vessels of the upper limbs. 2. Pectoral lymph nodes: lie along the lateral thoracic vessels, and receive the lymph vessels from anterolateral wall of thorax and abdomen, the lateral and central part of mammary gland. 3. Subscapular lymph nodes: lie on the posterior wall of axillary cavity and follow the subscapular vessels. They receive lymph vessels from the back of neck and the dorsal aspect of trunk (or neip). 4. Central lymph nodes: embedded in the fat of central part of axilla, and receive efferents from all the preceding axillary lymph nodes. 5. Apical lymph nodes: lie along the proximal side of the axillary vein, and receive lymph vessels from central lymph nodes and the upper part of breast. Their efferents unite to form the subclavian trunk. Ⅲ. The Lymph Vessels and Nodes of the Thorax parasternal lymph nodes lymph nodes of thoracic wall intercostals lymph nodes supraphrenic lymph nodes lymph nodes of thoracic anterior mediastinal lymph nodes viscera posterior mediastinal lymph nodes tracheobronchial lymph nodes bronchopulmonary lymph nodes Ⅰ)Anterior Mediastinal Lymph Nodes They are placed anterior to the large vessels of thoracic cavity and pericardium, and drained into the bronchomediastinal trunk. Ⅱ)Posterior Mediastinal Lymph Nodes They are in front of the esophagus and thoracic aorta, and drained into the thoracic duct. Ⅲ)Bronchopulmonary and Tracheobronchial Lymph Nodes pulmonary lymph nodes: along branches of bronchus and pulmonary a. receiving lymph ↓ vessels of lung. bronchopulmonary lymph nodes: in the hilus of each lung. ↓ tracheobronchial lymph nodes: around the bifurcation of trachea, draining (superior and interior) the lungs, bronchi, trachea, and heart. ↓ paratracheal lymph nodes: at the side of trachea. (right and left) ↓anterior mediastinal lymph nodes bronchomediastinal trunk (right and left) Ⅳ. The Lymph Vessels and Nodes of the Abdomen Ⅰ)The Lymph Vessels and Nodes of the Abdominal Wall Lumbar lymph nodes: lie along around the abdominal aorta and interior vena cava. They receive lymph vessels from the posterior abdominal wall, the abdominal paired viscera (kidney, suprarenal gland, ovary, testis, epididymis) and from the common iliac lymph nodes. Their efferents unite to form the right and left lumber trunks. Ⅱ)The Lymph Vessels and Nodes of Abdominal Unpaired Viscera They are dividable into celiac, superior mesenteric and inferior mesenteric lymph nodes, which lie around the origin of the corresponding artery. They receive the lymph vessels from the region which are supplied by the corresponding artery, their efferents unite to form intestinal trunk. 1. Celiac lymph nodes They are the terminal group for the stomach, duodenum, liver, gallbladder, pancreas and spleen, and their afferents are derived from the outlying lymph nodes which are placed along branches of the celiac artery. right and left gastric lymph nodes right and left gastroepiploic lymph nodes pyloric lymph nodes hepatic lymph nodes pancreaticosplenic lymph nodes 2. Superior mesenteric lymph nodes They receive efferents from the following lymph nodes. mesenteric lymph nodes ileocolic lymph nodes right colic lymph nodes middle colic lymph nodes 3. Inferior mesenteric lymph nodes They collect the lymph from the underlying lymph nodes. left colic lymph nodes sigmoid colic lymph nodes superior rectal lymph nodes Ⅴ. The Lymph Vessels and Nodes of the Pelvis They consist of three groups: external iliac lymph nodes, internal iliac lymph nodes and sacral lymph nodes, which collect the lymph from pelvic wall, viscera of pelvic cavity, and lower limbs. Their efferents pass to the common iliac lymph nodes, which are drained into right and left lumber lymph nodes. Ⅵ. The Lymph Vessels and Nodes of the Lower Limb Ⅰ)Popliteal Lymph Nodes They are imbedded in the fat of the popliteal fossa, and drained into deep inguinal lymph nodes. Ⅱ)Superficial inguinal Lymph Nodes They lie superficial to deep fascia, below the inguinal ligament, and along the terminal part of the great saphenous vein. They receive the superficial lymph vessels from the lower part of anterior abdominal wall, gluteal region, perineum,, external genital organs, the lower limbs except lateral side of the foot and posterolateral part of the leg. They send their efferents chiefly to deep inguinal lymph nodes. Ⅲ)Deep Inguinal Lymph Nodes They lie around terminal part of the femoral vein, receive efferents from the superficial inguinal lymph nodes and the deep lymph vessels of the lower limbs. Their efferents pass to external iliac lymph nodes. Section 4 The Spleen Ⅰ. Position It is situated in the left hypochondriac region, deep to the 9th to 11th rib and its long axis is in line of the 10th rib. It is not palpable below the left costal margin (arch). Ⅱ. Shape two surface diaphragmatic---convex visceral---concave, hilus of spleen two borders superior---sharper, splenic notch(2-3) inferior---blunter two extremities anterior posterior Section 5 The Thymus The thymus consists of two elongated lobes closely bounded by fibrous tissue. Its greater portion lies in the front of superior mediastinum of thoracic cavity, and lesser portion extends inferiorly into anterior mediastinum or superiorly into the neck. PART IV THE SENSE ORGANS Chapter 1 Introduction Sense organs are referred to the special receptors of the body, their structures consist of receptor and accessory apparatus, such as visual, auditory and vestibular apparatus. Receptors are the simple structures which receive the stimulation from the external or internal environment of the body. They may be divided into three kinds, viz. exteroceptors, enteroceptors, proprioceptors, on the bases of the location and the origin of the sense. Chapter 2 The Visual Apparatus The visual apparatus receives stimulation of light, and consists of eyeball and accessory apparatus. Section 1 The Eyeball The eyeball is embedded in the fat inside the orbit; spherical in shape. Anterior and posterior poles are referred to the central points of anterior and posterior surface of the eyeball, the line jointing the poles is termed the optic axis. An imaginary line encircling the eyeball, midway between the poles, is the equator. Visual axis joins the centre of the pupil to the central fovea of the retina, and decussate sharply with optic axis. cornea external tunic sclera iris walls middle tunic ciliary body choroids iridial part eyeball internal tunic blind part (retina) ciliary part optic art aqueous humor contents lens vitreous body ⅠThe Wall of the Eyeball It consists of three tunics, viz. external, middle and internal. Ⅰ)External Tunic(Fibrous Tunic) 1. Cornea: is the anterior 1/6, transparent, and more convex, nonvascular but rich in numerous sensory nerve terminals. 2. Sclera: is the posterior 5/6, white in colour and opaque, pierced by the optic nerve posteriorly. Venous sinus of sclera (Sachem’s canal) is a circular canal deep to the junction between the cornea and sclera. Ⅱ)Middle Tunic(Vascular Tunic) This layer contains numerous blood vessels and pigment cells and is brown in colour. 1. Choroid: is the posterior 2/3, and covers the inner surface of the sclera. 2. Ciliay body: lies at the inner surface of the junction of the cornea and the sclera, and consists of the ciliary ring, the ciliary processes and the ciliary muscles. The lens is attached to the inner side of the ciliary processes by the ciliary zonule (suspensory ligaments) 3. Iris: is the most anterior coloured part as a circular perforated disc. Near its centre is a round aperture. named pupil. Iris divide the space between the cornea and the lens into two parts, anterior and posterior chambers. Iridocorneal angle (angle of anterior chamber) is in anterior chamber, at which the cornea meet with the iris. Iris contains two sets smooth muscles, sphincter m. of pupil and dilator m. of pupil which are arranged circularly and radially respectively. Ⅲ)Internal Tunic (Retina) It may be divided into the optic part, the ciliary part and iridial part. The latter two part are known as the blind part, because of lacking light-sensitive elements. Optic disc is a white, round eminence at which the optic nerve pierces the retina. It is insensitive to light, and termed the “blind spot”. About 3.5mm to the temporal side of the optic disc, there is an oval yellowish area, named the macula lutea, it shows a central depression termed the central fovea, where visual acuity is highest. Ⅱ. The Contents of the Eyeball. They include the aqueous humor, the vitreous body, and the lens, which are all transparent and avascular, with the cornea altogether form the refractive media. Each plays a part in refracting the light entering the eye. Ⅰ)Aqueous Humor It is colourless and transparent water fluid, and fills the chambers of the eye. The circulating route of aqueous humor is as follows. Secreted by the ciliary bodyposterior chamberpupilanterior chamberiridocorneal anglevenous sinus of scleraanterior ciliary v. the veins of eye. Ⅱ)Lens It lies between the iris and the vitreous body. It is a transparent and elastic, biconvex body lacking vessels and nerves. Suspensory ligament connects the ciliary process to the capsule of the lens which encloses the lens. During near visionhe ciliary m.contractsciliary zonule relaxconvexity of lens increasesindex of refracting increasebringing near objects into sharp focus on retina Ⅲ)Vitreous Body It is a transparent, jelly-like substance which fills the space between the lens and the retina. Section 2 The Accessory Apparatus of the Eyeball The accessory apparatus of the eyeball includes the eyelid, the conjunctiva, the lacrimal apparatus, the extraocular muscle and the fasciae, the adipose corpus of orbit, et al. Ⅰ. Eyelids or Palpebrae Upper eyelid medial canthus palpebral fissure Lower eyelid lateral canthus From outside inwards, each eyelid includes: skin, subcutaneous tissue, orbicularis oculi m. tarsus and conjunctiva. Ⅱ. Conjunctiva It is a thin and transparent mucous membrane. palpebral conjunctiva ocular conjunctiva conjunctival fornices superior conjunctival fornix inferior conjunctival fornix Ⅲ. The Lacrimal Apparatus Ⅰ)Composition and Opening lacrimal gland-----------------------tears ↓ lacrimal punctum ↓ lacrimal canaliculus (superior and inferior) ↓ lacrimal passages lacrimal sac ↓ nasolacrimal duct ↓ lateral wall of inferior nasal meatus. Ⅱ)Location 1. Lacrimal gland: lies in the lacrimal fossa situated in superolateral portion of orbit. 2. Lacrimal sac: is lodged in the fossa of lacrimal sac situated in the medial wall of the orbit. Ⅳ. The Extraocular Muscles Which include the levator palpebral superioris, the four rectus and two oblique muscles. name action superior rectus inferior rectus medial rectus lateral rectus superior oblique inferior oblique superior palpebral levator nerve supply turn eye upward, inward turn eye downward, inward turn eye inward turn eye outward turn eye downward, outward turn eye upward, outward elevates upper eyelid Section 3 The Blood Vessels of the Eye Ⅰ. The Arteries of the Eye internal carotid a. ↓ ophthalmic a. superior nasal a. ↓ inferiorior nasal a. central retinal a.------- superior temporal a. inner layer of retina Ⅲ Ⅲ Ⅲ Ⅵ Ⅳ Ⅲ Ⅲ inferior temporal a. Ⅱ. The veins of the Eye They are two in number, the superior and inferior ophthalmic veins and are devoid of valves. Chapter 3 The Auditory and Vestibular Apparatus The auditory and vestibular apparatus is divided into three parts: the external, middle, and internal ears. The external and middle ears are a sound collecting and transmitting apparatus. The internal ear is such an organ that can receive the stimulaton of both sound waves and changes of the position of the head. auricle external ear external acoustic meatus tympanic cavity tympanic cavity middle ear auditory tube(pharyngotympanic tube) mastoid antrum mastoid air cells cochlea osseous labyrinth vestibule internal ear bony semicircular canals cochlear duct membranous labyrinth utricle and saccule membranous semicircular ducts Section 1 The External Ear Ⅰ. Auricle: projects from the side 0f the head.Auricular lobule ties below the auricle, and is composed of fibrous and adipose tissue. Ⅱ. External Acoustic Meatus: extends from the external acoustic porus to tympanic membrane. The lateral l/3 is cartilaginous, and the medial 2/3 is osseous. It is a curved tube.From outside inwards, first it runs forwards and upwards. then backwards,and finally forwards and downwards. In childhood, the external acoustic meatus is shorter and more narrow, the tympanic membrane is more horizontal. Section 2 The Middle Ear This part is between the external and inner ear. Ⅰ. Tympanic Cavity It is an irregular air-filled.space within the temporal bone, and contains auditory ossicles ligaments, muscles, vessels and nerves. It communicates anteriorly with the nasopharynx through the auditory tube, and posteriorly with the mastoid air cells through the mastoid antrum. Ⅰ)The Wall of the Tympanic Cavity 1. Superior wail (Tegmental wall) It is a thin plate separating the middle cranial fossa from the tympanic cavity. 2. Inferior wall (Jugular wall) It separates the tympanic cavity from the jugular fossa. 3. Anterior wall (Carotid wall) It is close to internal carotid artery. There are two parallel canals on this wall, semicanal for tensor tympani and semicanal for auditory tube. 4. Posterior wail (Mastoid wall) On the upper part, here is an opening of mastoid antrum, which passes to mastoid air cells through mastoid antrum, On the lower part, the pyramidal eminence and prominence of facial canal exist. 5. Lateral wail (Membranous wall) It is almost entirely formed by the tympanic membrane, only the superior part of this wall is formed by the lateral wall of the epitympanic recess. Tympanic membrane is oval and semi-transparent, lies obliquely between tympanic cavity and external acoustic meatus. Umbo is formed by the traction of the terminal point of the handle of the malleus. It also has two parts: flaccid part: upper 1/4 tense part: lower 3/4, cone of light 6. Medial wall (labyrinthine wall) It is the lateral wall of the inner ear. promontory: on the middle of this wall. vestibular window: posterosuperior to promontory. (fenestra ovalis) cochlear window: posteroinferior to promontory, closed by the secondary (fenestra rotunda) tympanic membrane in vivo prominence of facial nerve canal: posterosuperior to vestibular window. Ⅱ)The Auditory Ossicles The tympanic cavity contains a chain of three ossicles: the malleus incus, and stapes, which connects the tympanic membrane and the fenestra vestibule. Ⅱ. The Auditory Tube Lateral1/3--bony partpharyngeal orifice of auditory tubenasopharynx Medial 2/3--cartilaginous partorifice of tympanic cavity of auditory tubetympanic cavity The auditory tube is shorter,wider and horizontal in infant, therefore the pharyngeal inflammation may along the auditory tube spread into the tympanic cavity. Ⅲ. The Mastoid Ant rum and Mastoid Ai r Cells The mastoid antrum is air-filled space between the tympanic cavity and the mastoid air cells. Mastoid air cellsmastoid antrumtympanic cavity (posterior) (middle) (anterior) Section 3 The Internal Ear The internal ear lies between the tympanic cavity and the base of the internal acoustic meatus, viz. in the petrous part of the temporal bone. Osseous labyrinth perilymph Membranous labyrinth endolymph Ⅰ. The Osseous Labyrinth It includes the cochlea, the vestibule and the semicircular canals, from before backwards along the long axis of the petrous part of the temporal body. Ⅰ)Vestibule posterior: five openingsemicircular canal anterior: one openingcochlear fenestra vestibule fenestra cochleae Ⅱ)Bony semicircular Canals ampullar crus(bony ampulla) anterior semicircular canal single crus commune crus single crus posterior semicircular canal ampullar crus(bony ampulla) lateral semicircular canal single crus (horizontal semicircular canal) ampullar crus(bony ampulla) Ⅲ. Cochlea It resembles the shell of a snail. It is composed of the bony canal of cochlea winding spirally for 5/2~11/4 turns around the central modiolus which projects the osseous spiral lamina. The bony canal is divided into two parts by this lamina and the basilar membrane of the cochlear duct. scala vestibule-------upper part two parts (vestibular scale) communicating through helicotrema scala tympani-------lower part (tympanic scale) cochlear apex--------toward anterolateral apex and base (cochlear cupula) cochlear base--------toward bottom of internal acoustic meatus Ⅱ. The membranous Labyrinth It is a series of membranous canal and sacs which lie within the bony labyrinth. From before backwards, it includes: the cochlear duct, the utricle and saccule, and the membranous semicircular ducts. Ⅰ)The Utricle and Saccule -----------------------membranous semicircular duct five opening utricle------posterosuperior part: macula of utricle ↑ (base) ∣ utriculosaccular duct static balance organs ↓ saccule------anteroinferior part: macula of saccule (anterior wall) --------------------cochlear duct uniting duct Ⅱ)The Membranous Semicircular Ducts They lie within the bony semicircular canal, and are similar to them in shape and names. On the wall of membranous ampulla, there are the ampular crests which are the organs of kinetic balance. Ⅲ)The Cochlear Duct It lies in the bony canal of the cochlea. A transverse section through the cochlea shows that this canal is divided into three separated channels, namely, the tympanic scale, the vestibular scale and the cochlear duct. The cochlear duct is triangular on the transverse section, and has three walls. vestibular scale superior wall: vestibular membrane cochlear duct lateral wall: the thickened endosteum osseous spinal lamina inferior wall: basilar membrane tympanic scale (spiral membrane) cochlear duct The spiral organ is the receptor for auditory sensation, situated on the basilar membrane. Ⅲ. The Internal Acoustic Meatus. It is a short canal within the petrous part of the temporal bone. Liu Zhiyu (刘执玉) PART Ⅴ THE NERVOUS SYSTEM Chapter 1 Introduction The nervous system is a master system in the living body, it regulates and intergrates the activities of all the other bodily systems for the benefit of the organism as a whole: Ⅰ. Subdivision of Nervous System The nervous system may be divided into the following parts: telencephalon brain diencephalon central nervous cerebellum midbrain system﹙CNS﹚ brain stem pons medulla oblongata spinal cord peripheral cranial nerves (12 pairs) nervous spinal nerves (31 pairs) system (PNS) visceral sensory n. visceral n. sympathetic n visceral motor n. parasympathetic n. Ⅱ. The Activity Mode of Nervous System The functional unit of the nervous system is the reflex arc, a linkage of afferent and efferent neurons 1. receptor 2. afferent n. (sensory n.) reflex arc 3. center 4. efferent n. (sensory n.) 5. effector Ⅲ. The Basic Terminology in Nervous System Ⅰ)Terms in CNS 1. Grey matter----collections of cell bodies and dendrites. 2. White matter----collections of nerve fibres. 3. Cortex----a mantle of grey matter on the brain,such as cerebral cortex. 4. Nucleus----a group of cell bodies which have the same shape and function. 5. Tracts----In white matter, a bundle of nerve fibres which have the same origin, terminaion, passway and function。 Ⅱ)Terms in PNS 1. Ganglion----collections of cell bodies。 2. Nerve----collections of nerve fibres held together by connective tissue sheath。 Chapter 2 The Peripheral Nervous System The peripheral nervous system ( PNS ) is the nervous structures out-side the brain and spinal cord. It is composed of nerves and ganglia, and usually divided into three portion: ①cranial nerve attaching to the brain. ② spinal nerve attaching to the spinal cord. ③visceral nerve innervating the viscera, heart and vessels, and gland. Section 1 The Spinal Nerves There are thiry-one pairs of spinal nerves, each of them arises from two roots attached to the cord, an anerior root (motor fibres ) and a posterior root (sensor fibres). Two roots unite o form the spinal nerve at the intervertebral foramen. The spinal ganglion is an enlargement of the posterior root near the intervertebral foramen. cervucak n. ----8 pairs thoracic n. ----12 pairs Spinal n. (31 pair) lumbar n. ----5 pairs sacral n. ----5 pairs coccygeal n. ----1 pairs The spinal nerves are mixed nerves which contain two kinds of fibres. somaic sensory fibres-supplying skin, skele-tal m., tendon and joint. Sensory nerve fibres visceral sensor fibres-supplying viscera, heart and vessels, and gland. somaic motor fibres-innervating skeletal m. Motor nerve fibres visceral motor fibres-innervating cardiac m. smooh m. and gland. The trunk og spinal nerve is short and gives off two major branches, ①larger mixed n. anterior ramus (venral ramus ) posterir ramus (dorsal ramus) ②suppling the skin and muscles of anterolateral region of the body and upper and lower extremities. ③forming plexus: cervixal, brachial, lumbar and sacralplexuses, except ventral rami of thoracic n. ①smaller mixed n. ②supplying the skin and muscle of dorsal region of the body ③segmental distribution Ⅰ. The Cervical Plexus Ⅰ)Formation It is frmed by the anterior rami of the four upper cervical n. (C1-4). It is situated deeply in the upper part of the neck, covered by the upper part of the sternocleidomastoid m., and anterior to the levator scapulae and scalenus medius muscles. Ⅱ)Branches 1. Superficial (cutanous) branches They emerge near the middle point of the posterior border of the sternocleiddomastoid m. and have a fan-shaped distribution. lesser occipital n. great auricular n. transverse cervical n. supraclavicular n 2. Deep (muscular) branches The most important branch of the cervical plexus is phrenic nerve, a mixed nerve. Anterior rami of cervical n. 3~5phrenic n. laeral border of anterior scalene m. inlet of thorax aterior, medial to the m. between subclavian a. and v. -----------------------thoracic cavityin front of the root of lung between pericardium and mediastinal pleuradiaphragm. Motor fibresdiaphramg pleurac, pericardium, peritoncum. Sensory fibres right phrenic n. liver,gallbadder, and bile duct. Ⅱ. The Brachial Plexus Ⅰ)Formation It is formed by anterior rami of nerver C5~8 and T1. It is situated in the supeoposterior side of subclvian a., behind the clavicle, and in axillary fossa. Five rootsthree trunks (upper, moddle and lower) two divisions (anterior, posterior) three cords (lateral ,medial and posterior) severn important branches. Ⅱ)Branches 1. Long thoracic n. supplying the anterior seratus m. 2. thoracodorsal n. supplying latissimus dorsi m. 3. Axillary n. Posterior cordaxillary n. quadrilateral pacewinding round surgical neck of humerusdeep to detoid m. Muscular branchesdeltoid m., teres minor m. Cutancous branches skin on shoulder and superolateral part of arm. 4. Musculocutaneous n. Lateral cord musculocutaneous n. piecing coracobrachialis m. between bieceps branchi and branchialis m. Muscular branches the three m. above. Cutanous branches (lateral antebrachial cutanous n.) skin of lateral side of forcarm. 5. Median n. Two roots of medial cord and lateral cordembracing axillary a. median n. medial to biceps brachii m. in armcrossing branchial a. cubital fossapiercing pronator teres m. carpal canal ------------------------wristhand. Muscular branchesm. in front of forearm except brachioradialis m. flexor carpi ulnaris m. and ulnar half of flexor digitorum pro-fundus m.; m. of thenar eminence except adductor pollicis m. 1~2 lumbricalis m. Cutanous branchesradial half of palm ;pslmar surface of radial 31/2 fingers. 6. Ulnar n. Medial cordulnar n. medial to axillary a. piercing medial intermuscular septumback of armulnar grooveforearm, wrist, hand. flexor carpi ulnaris m. ulnar half of flexor digitorum profundus m. muscular branches adductor pollicis m. hypothenar eminence interosseous m. (palmar, dorsal) 3~4 lumbricalis m. cutanous branchesskin on ulnar side of hand;palmar and dorsal surface of ulnar 11/2and 21/2fingers. 7. Radial n. Posterior cordradial n. behind axillary a. between long and medial head of triceps m. radial groove lateral superfical branch ---------------------lateral side of arm---------------------------- epicondyle of humberus deep branch brachiordialis m. Muscular branches extensors of arm and forearm. skin on dorsal surface of arm and forearm Cutaneous branches skin on dorsal surface of lateral half of hand and lateral 21/2 Ⅱ. The Ventral Rami of the Thoracic Nervers They are twelve pairs: the uuper eleven are called intercosal n., which pass into intercosal space and run between internal and exteral intercostals m. along costal groove; the twelfth is called subcostal n. They supply muscles and skin of the thoracic and abdominal wall. The distribution of the anterior branches of the thoracic nerves is segmental. On the anterior surface of trunk, they present about the level of: T2——the sternal angle T4——the nipple T6——the xiohoid process T8——the costal arch T10——the umbilicus T12——the midpoint between umbilicus and symphysis pubis (or anterior superior iliac spine) Ⅳ. The lumbar Plexus Ⅰ)Formation It is derived from anterior rami of nerver T12, L1-4 and coverd by the psoas major m. Lumbosacral trunk is formed by anterior rami of part of L4, L5 nerves, to take part in sacral plexus. Ⅱ)Branches 1. Femoral n. Descending between psoas major and iliacus m. deep to inguinal ligament muscular spacefemoral trigone in front side of thigh pectineus m. Muscular branches quadriceps femoris m. sartorius m. skin of anterior surface of thigh and knee joint. Cutaneous branches saphenous n.-medial side of leg and foot. 2. Obturator n. Medial border of psoas major m. along lateral pelvic wall through obturator through obturator canal canal-----------------------------------------medial part of thigh. Muscular branchesm. of medial group of thigh Cutaneous branchesskin of medial sie of thigh Ⅴ. The Sacral Plexus Ⅰ)Formation It is formed by lumbosacral trunk (L4, 5), the ventral rami of sacral n. (S1, 5) and coccygeal n. (C0). It is tocated in front of sacrum and piriformis m., and behind internal iliac a. Ⅱ)Branches 1. Superior gluteal n. It leaves the pelvis via the greater sciatic foramen above the piriformis m.and supplies the gluteus medius m., glutecus minimus m., and tensor fasciae latae m. 2. Inferior gluteal n. It leaves the pelvis through the greaer sclatic foramen below the piriformis m. and distributes the gluteus maximus m. 3. Pudendal n. Greater sciatic foramen inferior to piriformis m. winding round ischial lesser sciatic foramen spine------------------------------------ischiorectal fossainnervating m. and skin of the perineum and external genital organs. inferior rectal n. (anal n.) Its branches perineal n. dorsal n.of penis or clitoris 4. Sciatic n. It is largest nerve in the body. Leaving pelvis through greater sciatic foramen below piriformis m. deep to gluteus maximus m. between ischial tuberosity and greater trochanter of femurposterior compartment of thighdeep to biceps femoris m. uperior angle of popliteal fossatibial n. and common peroneal n. The trunk of sciatic n. supplies the muscles of posterior group of thigh. 1)Tibial n. Descending in popliteal fossadescending and supplying muscles of posterior group of medial planter n. legbehind medial malleolusplantar lateral planter n. skin and m. in dorsum of foot. 2)Common peroneal n. Descending along medial border of biceps femoris m. winding aroud fibular neck tofront side of leg peroneus longus and brevis m. Superficial peroneal n. ---- skin of lateral side of leg, dorsum of fot and toes. --------- m. of anterior group of leg, dorsum Deep peroneal n. ---------- of foot skin between the first and second toes. In summary, the common peroneal n. supplies the muscles of anterior and lateral group of leg, and the skin on lateral side of leg, dorsum of foot and toes. Section 2 The Cranial Nerves There are twelve pairs of cranial nerves attach to brain , which leave or enter the skull through a series of foramina in the base of the cranium.They are listed as follows by Roman numerals. Nature, Origin and Passage of Cranial Nerves Nerve Nature ⅠOlfacotry ⅡOptic ⅢOculomotor ⅣTrochlear sensory sensory motor motor ⅤTrigeminal mixed Superfical origin on brain telencephalon diencephalons midbrain midbrain pons Passage of the skull cribriform foramen optic canal superior orbital fissure superior orbital fissure superior orbital fissure (ophthalmic) round foramen ⅥAbducnet motor pons ⅦFacial mixed pons ⅧVestibulocochlear ⅨGlossoPharyngeal ⅩVagus ⅪAccessory ⅫHypoglossal (maxillary) oval foramen (mandibular) superior orbital fissure internal acoustic port facial canal stylomastoid foramen internal acoustic port senory pons mixed medullaoblongata jugular foramen mixed motor motor medullaoblongata medullaoblongata medullaoblongata jugular foramen jugular foramen hypoglossal canal They components of cranial n. are more complex than tha of spinal n., the former consists of seven kinds of fibres. General somatic sensory fibres Special somatic sensory fibres Sensory fibres General visceral sensory fibres Special visceral sensory fibres General somatic motor fibres Motor fibres General visceral motor fibres Special visceral motor fibres Ⅰ. Olfactory Nerve (CN I) It is a sensory n. and serves the smell sense. Central processes of olfactory cells in mucous membrance of upper parts of superior nasal cribriform plate concha and nasal septumolfactory fibres-------------------------------------olfactory bulb. Ⅱ. Optic Nerve (CN Ⅱ) It is composed by special somatic sensory fibres conducting visual stimulation. optic disc optic canal Ganglion cells of retina-------------piercing scleraoptic n. ------------------middle cranial fossaoptic chiasma, optic tractdiencephalon. Ⅲ. Oculomotor Nerve(CN Ⅲ) somatic motor n.- oculomotornucleus Motor n. --------------- visceral motor n.-accessory oculomotor nucleus (Edinger-Westphal nucleus) interpeduncular fassa oculomotor n. -------------------------------------leaving skull---------lateral wall of cavernous superior orbital fissure sinus---------------------------------------------------------------orbtial cavity superior rectus m. superior ramus -------------------- inferior ramus levator palpebrae superioris m. inferior retus m. medial retus m. inferior oblique m. A short branch given off by the n. for inferior oblique m. (parasymatthetic n.) ciliary sphincter m. of pupil (iris) ganglion (relay) sphincter m. of pupil (relay) ---- ciliary m. reflex of light(pupil) ------- regulating convexity of lens Ciliary ganglion is a parasympathetic ganglion situated between optic n. and lateral rectus m.near orbital apex. Ⅳ. Trochlear Nerve (CN Ⅳ) This is the smallest cranial nerve. Leaving skull below inferior colliculus of midbraincurving around lateral surface of cerebral pedunclelateral wall of cavernous sinusuperior orbital fissureorbitsupplying superior oblique m. Ⅴ. Trigeminal Nerve(CN Ⅴ) This is the largest one of cranial nerve and a mixed nerve containing somatic sensory and special visceral fibres. Motor, pontil, spinal tract, mesencephatic nuclcus of trigeminal n. larger sensory root ophthalmic n. trigeminal n. maxillary n. smaller motor root mandibular n. Sensory fibres: skin of face (divided by mouth slit, palpebral fisure); mucousmembrance, ---- of oral cavity,nasal cavity,paranasal sinus;teeth, brain meninges. Motor fibres: m. of mastication, mylhyoid m. anterior belly of digastric m. Trigeminal ganglion is a sensory ganglion situated in anterior surface of apex of petrous part of temporal bones. Ⅰ)Ophthalmic Nerve It is a sensory nerve. Trigeminal ganglionophthalmic n. lateral wall of cavernous sinussuperior orbital fissureorbit. 1. Lacrimal n. This nerve supplies the lacrimal gland and the upper eyelid. 2. Frontal n. It has 2~3 branches , in which the supraorbital nerve passes through the supraorbital notch (or foramen) to the skin of the frontal area. 3. Nasociliary Nerve It supplies the nasal mucous membrane, ethmoidal sinuses, lacrimal sac, the skin of dorsal surface of the nose, eyeball, and eyelid. Ⅱ)Maxillary Nerve It is a sensory nerve. Trigeminal ganglion----maxillary n. ---------lateral wall of cavernous sinus-------round orbit foramen-------inferior orbital fissure---------------infraorbital n. 1. Infraorbital n. Maxillary n. orbitinfraorbital groove, canal, foramenskin of lower eyelid, nose, and upper lip. 2. Zygomatic n. It supplies the skin of the temporal and zygomatic area of face. Parasymapathetic postganglionic fibres from facial n. zygomatic n. communicating branchlacrimal n. lacrimal gland. 3. Supperior alveolar n. Anterior, middle, posterior branchessuperior dental plexusmaxillary sinus, upper teeth and gums. Ⅲ)Mandibular Nerve It is a mixed nerve and the largest division of the trigeminal nerve. smaller anterior trunk: mainly motor n. Leaving skull through oval foramen--------- larger posterior trunk: mainly sensory n. 1. Auriculotemporal n Arising by two rootsencircling meningeal a. piercing parotid glandtemporal regionskin of temporal area. Parasympathetic secretory fibres from glossopharyngeal n. auriculotemporal n. parotid gland. 2. Buccal n. It supplies the skin and mucous membrane of the check. 3. Lingual n. general sense--anterior 2/3 mucous membrane of tongue and floor of oral cavity. ligual n. special sense: chorda tympani (taste sense) of facial n. lingual n. tastefibres-------------tastebud of anterior 2/3 tongue. parasympathetic secretory fibres--------------- -------------------submandibular ganglion (relay) ----submandibular and lingual gland. 4. Inferior alveolar n. terminal branch A mixed n. submanidibular foramen, canalinfeior alveolar plexus------------------------- mental foramenmental n. sensory fibres----lower teeth, gum, skin and mucous membrane of chin and lower lip. Moter fibres ----mylohyoid and anterior belly of digastric m. 5. Nerve of muscles of mastication It innervates all muscles of mastication. Ⅵ. Abducent Nerve (CN Ⅵ) Arising from abducent nucleuspontomedullary groovein cavernous sinus lateral to internal carotid a. superior orbital fissureorbitsupplying lateral rectus m. Ⅶ. Facial Nerve (CN Ⅶ) special visceral motor fibres (facial nucleus) general visceral motor fibres (superior salivatory mucleus) special visceral sensory fibres (geniculate ganglion) Emerging from pontomedullary groove lateral to abducent n. internal acoustic meatusfacial canalstylomastoid foramenpiercing parotid glandface. Ⅰ)The Vranches within the Facial Canal lingual n. taste fibrestaste bud of anterior 2/3 tongue. Chorda tympani----------- parsympathetic fibressubmandibular ganglion submandibular and lingual gland. Ⅱ)The Branches outside the Facial Canal Facial n. parotid plexus (in parotid gland ) five branches temporal branch: frontal m. and orbicularm. Of eye. zygomatic branch: zygomatic m. and orbicular m. of eye. buccal branch: buccinatorm. And orbicular m. of mouth. mandibular branch: m. of lower lip. cervical branch: platysma m. The facial n. also gives off amall muscular branches to occipital m., posterior auricular m., posterior belly of digastric m., and stylohyoid m. Pterygopalatine ganglion is a parasympathetic ganglion located in the pterygopalatien fossa under the maxillary nerve. Submandibular ganglion is also a parasympathetic ganglion situated below the lingual nerve, deep to submandibular gland. Ⅷ. Vestibulocochlear (Auditory ) Nerve (CN Ⅷ) cochlear part (nerve) --------auditory sense Two parts vestibular part (nerve) --------balance sense (equilibrium) Ⅰ)Vestibular Nerve Macula of utricle and sccule peripheral processes Ampullary crest of membranous ←————————vestibular ganglion semicircular canal central processes (in bottom of internal acoustic meatus)——————→vestibular n. →internal acoustic meatus enter skull ——————→vestibular nuclei (in brain stem). Ⅱ)Cochlear Nerve peripheral central Spiral organ←——————spiral ganglion (in modiolus)——————→internal acoustic processes processes meatus→pontomedullary groove→dorsal and ventral cochlear nuclei (in brain stem). Ⅸ. Glossopharyngeal Nerve (CN Ⅸ) special visceral motor fibres general visceral motor fibres (parasympathetic fibres) special visceral sensory fibres general visceral sensory fibres general somatic sensory fibres This nerve is a mixed n. in nature and origins on the posterolateral sulcus in the medulla oblongata. It leaves the skull with the vagus nerve and accessory nerve through the jugular foramen. On its trunk there are two sensory ganglia, the superior and inferior. Ⅰ)Tympanic Nerve Tympanic n. tympanic plexuslesser petrosal n. otic ganglionauriculotemporal n. parotid gland. Otic ganglion is also a parasympathetic ganglion situated below ovalforamen. Ⅱ)Carotid Sinus Branch They run downward along internal carotid artery to supply the carotid body and carotid sinus. Ⅲ)Lingual Branches They supply the posterior third of the mucous membrane and taste bud of tongue for general and taste sense. Ⅹ. Vagus Nerve (CN Ⅹ) It is the mixed nerve of the longest route and widest distribution. viscera in cervical part, and thoracic general visceral motor fibres: and abdominal cavity innervating cardiac, (parasympathetic fibres) smooth., and gland. visera in cervical part and general visceral sensory fibres: thoracic and abdominal cavity general somatic sensory fibres: dura mater, skin of auricle and external acoustic meatus. special visceral motor fibres: laryngeal and pharyngeal m., soft palate. Emerging from posterolateral sulcus in medulla oblongataleaving skull through jugular foramenforming superior and inferior ganglianeckdescending within carotid sheath (behind internal jugular v. and internal carotid or common carotid a. ) root of necksuperior thoracic aperturethoracic cavity: Left vagus n. between left common carotid a. and subclavian a. anterior to aortic archposterior to root of left lung (left pulmonary plexus) descending in front of esophagusesophageal plexusanteior vagal trunkthrough esophageal opening of diaphragm anterior gastric branch abdominal cavity----- hepatic branchhepatic plexus Right vagus n. in front of subclavian a. right to tracheabehind root of right lung (right pulmonary plexus) descending posterior to esophagusesophageal plexusposterior vagal trunkthrough esophageal opening of diaphragmabdominal cavity posteror gastric branch celiac branchceliac plexus Ⅰ)The Branches in the Neck Superior laryngeal nerve Inferior ganglionmedial to internal carotid a. greater cornu of hyoid bone internal laryngeal branchcricothyroid m. ------- esternal laryngeal branchpiercing thyrohyoid membranemucous membrane of larynx above slit of glottis for sense. Ⅱ)The Branches in the Thorax Recurrent laryngeal nerve Right: higher, winding right subclavian a. -----groove between trachea and esophagus Left: lower, winding aortic arch lower border of inferior pharyngeal constrictor m. inferior laryngeal n. larynx. Motor fibres: all laryngeal m. except cricothyroid m. Sensory fibres: mucous membrane of larynx below the slit of glottis Ⅲ)The Branches in the Abdomen 1. Anterior gastric branch along lesser curvature of stomach Anterior vagal trunkanterior gastric branch------------------------------------------------------- anterior gastric wall 4~6 small branches -----------------------------terminating in “crow’s foot” anterior wall of pyloric part (canal and antrum) 2. Hepatic branch Anterior wagal trunkhepatic branchhepatic plexus 3. Posterior gastric branch along lesser curvature of stomach Posteror vagal trunkposterior gastric branch-------------------------------------------------4~6 posterior gastric wall small branches---------------------------------terminating in “crow’s foot” posterior wall of pyloric part (canal and antrum) 4. Celiac branch Posterior vagal trunkceliac branchceliac plexussupplying liver, pancreas, kidneys, spleen, small intestine, caccum, transverse colon, ascending colon, appendix, (digestive canal prior to left colic flexure) Ⅺ. Accessory Nerve (CN Ⅺ) It is a motor nerve (special visceral motor fibres ), formed by the union of the cranial and spinal roots. Cranial root (ambiguous nucleus): emerging from posterolateral sulcus in medulla oblongataleaving skull through jugular foramenjoining vagus n. laryngeal and pharyngeal m. Spinal root (accessory nucleus of cervical segments in spinal cord): entering skull through foramen magnumsternocleidomastoid m. and trapezius m. Ⅻ. Hypoglossal Nerve (CN Ⅻ) It is mainly composed of somatic motor fibres. Hypoglossal n. (hypoglossal nucleus ) emerging from anterolateral sulcus of medulla oblongataleaving skull through hypoglossal canalbetween internal carotid a. and internal jugular v. supplying all extrinsic and intrinsic m. of tongue. Section 3 The Visceral Nervous System The visceral nervous system has two group of fibres, i.e. sensory fibres and motor fibres, is a part of the nervous system distributed in the viscera, cardiovascular system and secretory glands. The motor fibres are also termed autonomic or vegetative fibres because they regulate the common involuntary metabolic activities of the animal and vegetable. Ⅰ. Visceral Motor Nerves Differences between Visceral and Somatic Motor Nerves Somatic n. 1. skeletal m. 2. one kind of fibres 3. a single neuron (lower cntre effector) 4. distributed in the form of nerve trunk 5. thick myelinated fibres 6. voluntary consciousness Visceral n. cardiac m. smooth m., and gland sympathelic fibres two parasympathetic fibres two neurons preganglionic neuron (fibre) postganglionic neuron (fibre) nerve plexus preganglionic-thin myelinated fibres postganglionic-unmyelinated fibres involuntary unconsciousness In visceral motor nerve, two neurons are needed from lower nervous centres to effector. Preganglionic neuron is the first neuron whose cell body is located in the brain stem and spinal cord, and sends out the pregangliionic fibres. Postganglionic neuron is the second neuton situated in the peripheral visceral nerve ganglia, and gives rise to postganglionic fibres. The visceral motor nerve is divide into the sympathetic and parasympathetic division on basis of their features in function, shape, pharmacology and neurobiachemisty. Ⅰ)Sympathetic System 1. Position of lower centres They are situated in lateral grey horn of T1 (C8 ) ~L2 (L3 ) segments of the spinal cord. This division is also termed the thoracolumbar part. 2. Peripheral part prevertebral ganglion sympathetic ganglion paravertebral ganglion branches from the ganglia sympathelic plexus 3. Sympathetic ganglia 1) Parasympathetic ganglia They arranged symmetrically on either side of the spinal colum, and are connected by interganglionic branches to form two sympathetic trunks, that extend from the base of the skull to the coccyx and are divided into cervical, thoracic, lumbar, sacral and coccygeal portions. Ganglion impar is unpaired ganglion formed by fusing of two sympathetic trunks at the coccyx. 2) Prevertebral ganglia They are located in front of vertebral column. celiac ganglia aorticorenal ganglia superior mesenteric ganglia inferior mesenteric ganglia 4. Communicative ramus They are divided into white and grey ones to link the sympathetic ganglion with the corresponding spinal nerve. 1) White communicative rami They are the preganglionic fibres send by the nerons of lateral horn in T1~L3 segments of the spinal cord. Preganglionic fibresanterior rootspinal n. white communicative ramiparavertebral ganglion. The preganglionic fibre of a white communicative ramus, after entering the sympathetic trunk, may terminate in three ways: ①Ending in corresponding paravertebral ganglia. ②Passing up and down in the trunk to terminate in paravertebral ganglia above and below. ③Passing through paravertebral ganglia. 2) Grey communicative rami They are the postganglionic unmyelinated fibres, emitted by paravertebral neurons and situated between the sympathetic trunk and the 31 pairs of spinal nerve. They also course in three ways: ①Accompanying with corresponding spinal n. to peripheral blood vessels, sweat gland, and arrector pili m. (arrector m. of hair) . ②Surrounding artery as a layer of nerve plexus to innervate the branches of that arteries. ③Terminating in certain organs derectly. 5. The general distributions of sympathetic nerve 1) Cervical portion of sympathetic trunk It is dorsal to the carotid sheath and ventral to the transverse processes of the cervical vertebrae. superior cervical ganglion: in front of C2, 3 transverse processes middle cervical ganglion: C6 inferior cervical ganglion: C7 Cervicothoracic ganglion (stellate ganglion) is the ganglion fused by inferior cervical ganglion with the first thoracic ganglion. The distributions of postganglionic fibres are: ①Through 8 pairs cervical n. to vessels of upper limb, head and neck. ②Surround the arteries to form internal and external carotid plexus, subclavian plexus, vertebral plexus to smooth m. and gland of upper limb, head and neck. ③Pharyngeal branchpharyngeal plexuscardiac plexuscardiac m. 2) Thoracic portion of sympathetic trunk It is in front of the heads of the ribs and 10~12 pairs in number. ①Through 12 pairs of intercostals n. to blood vessels, gland, arrector pili m. of abdominal and thoracic wall. ②The upper 5 ganglia to thoracic aorta, esophagus, trachea, bronchi and to take part in pulmonary and cardiac plexus. ③Greater splanchnic n. It is formed by contributions from 5 (6) ~9 (10) thoracic ganglia (preganglionic neuron ), which terminate in the celiac ganglion. ④Lesser splanchnic n. It is formed by branches (preganglionic fibres) of 10~12 thoracic ganglia, which end in the aorticorenal ganglion. The postganglionic fibres of the celiac and aorticorenal ganglia supply the liver, spleen, kidney and digestive tract as far as the left colonic flexture. 3) Lumbar portion of sympathetic trunk It is ventrolateral to the body of lumbar vertebra and along the medial margin of the psoas maior muscle. ①Distributing through 5 pairs lumbar n. ②Lumbar splanchnic n. It is formed by the preganglionic fibres terminating in abdominal aortic plexus and mesenteric plexus. After exchanging neurons in these plexus, the postganglionic fibres supply the digestive tract below left colonic flexure, pelvic viscera, and lower limbs. 4) Pelvic portion of sympathetic trunk It lies against the ventral surface of the sarum, and medial to anterior sacral foramen. ①Supplying through sacral and coccygeal n. ②Taking part in pelvic plexus. Ⅱ)Parasympathetic System 1. Lower centre It lies in the cranial parasympathetic nuclei in brain stem and S2~4segments of the spinal cord (sacral portion). 2. Peripheral part apraorgan ganglia parasympathetic ganglia intraorgan ganglia fibres sending off from these ganglia parasympathetic plexus ciliary ganglion paraorgan submandibular ganglion ganglia sphenopalatine ganglion otic ganglion 3. Cranial portion of parasympathetic system Their preganglionic fibres run in the cranial nerves Ⅲ, Ⅶ, Ⅸ, Ⅹ, the details about this will be presented here. 1) Parasympathetic nucleus of oculomotor nerve (Edinger-westphal nucleus) Preganglionic fibres from E-W nucleusoculomotor n. (Ⅲ) ciliary ganglion (relay) postganglionic fibresciliary m. and pupillary sphincter m. 2) Superior salivatory nuclei Preganglionic fibres from superior salivatory nucleifacial n. (Ⅶ) greater petrosal n. pterygopalatine ganglion (relay) maxillary n. zygomatic n. lacrimal n. lacrimal gland. postganglionic fibres gland in nasal, oral cavity and mucous membrane of palatine. Facial n. chorda tympapnilingual n. submandibular ganglion (relay) postganglionic fibressubmandibular gland and sublingual gland. 3) Inferior salivatory nuclei Preganglionic fibres from inferior salivatory nucleiglossopharyngeal n. (Ⅸ) tympanic n. tympanic plexuslesser petrosal n. otic ganglion (relay) postganglionic fibresauriculotemporal n. parotid gland. 4) Dorsal motor nucleus of vagus Preganglionic fibres dorsal motor nucleus of vagusvagal n. (Ⅹ) abdominal and thoracic viscera (synapse) postganglionic fibrescorresponding abdominal and thoracic organs (except descending colon, sigmoid colon and pelvic viscera). 4. Sacral portion of parasympathetic system Their preganglionic fibres arising from parasympthetic nuclei in S2~4 segments of spinal cord form pelvic splanchnic nerve, which takes part in pelvic plexus. After exchanging the neurons, the postganglionic fibres innervate the alimentary canal distal to left colonic flexure, pelvic viscera and external genital organs. Ⅲ)Differences between Sympathetic and Parasympathtetic Nerve 1. Different central centre sympathetic----thoracolumbar part: C8 (T1) ~ L2 (L3) cranial part: brain stem parasympathetic---sacral part: S2~4 2. Different locations of peripheral ganglia prevertebral sympathetic paravertebral preganglionic fibre is shorter paraorgan parasympathetic intraorgan preganglionic fibre is longer 4. Different distributions sympathetic----much wider parasympathetic----much narrowly, without nerve supply in blood vessels, sweat gland, arrector pili m., medullary part of suprarenal gland. 5. Different actions to a visceral organ The viscera receives a dual autononic supply. In most cases, the two sets of nerves function antagonistically to one another. Such as: increasing heart-beating elevating blood pressure sympathetic dilating bronchi wider opening of pupil inhibiting digestive activity parasympathetic: on the contrary Ⅳ)The Visceral Plexuses The sumpathetic nerve and parasympathetic nerve are usually combined with the visceral sensory nerve into extensive plexuses called visceral plesuses in the way to viscera. 1. Caridiac plexus It is formed by superior, middle, infeior cervical ganglia, cardiac branches sending off from T1~5 ganglia and supplies the cardiac muscles. superficial cardiac plexus----below aortic arch. deep cardiac plexus----between aortic arch and bifurcation of trachea. 2. Pulmonary plexus It lies in front of and behind the root of lung called anterior and posterior pulmonary plexus respectively, which supply the lung. 3. Celiac plexus It is located in front of abdominal aorta, and surrounds the roots of the celiac and superior mesenteric arteries. Secondary plexus----hepatic, splenic, pancreatic, superior mesenteric, gastric, renal plexuses. 4. Abdominal aortic plexus It is caudalward continuation of celiac plexus. 5. Hypogastric plexus superior hypogastric plexus----in front of L5 vertebra between two common illiac a. inferior hypogastric plexus----both sides of rectum. Ⅱ. The Visceral Sensory Nerves They conduct the impulse from enterioceptor of the viscera to the central nervous system. The visceral sensory fibres have their own features in function and morphology which are different from those of the somatosensory ones. 1. The mumber of the visceral sensory fibres is less. 2. A high pain threshold. 3. Poorly localized visceral sensation (general feeling). 4. Insensitive to cutting, crushing, burning. 5. Sensitive to excessive tension, contraction of smooth m., and certain pathological condition. Chapter 3 The Central Nervous System Section 1 The Spinal Cord Ⅰ. External Features Ⅰ)The Spinal Cord: a culindrical structure and slightly flattened anteroposteriorly, is locatedin the vertebral canal and invested by meninges. upper end: continuing with medulla oblongata at the level of foramen magnum. Inferior border of L1 vertebra in adult. lower end: L3 vertebra in baby. The spinal cord tapers gradually and becomes conical termination known as midullary cone. A slender nerveless structure descending from medullary cone is termed filum terminale. Cauda equine, a divergent sheaf of caudal spinal roots, is gathered around the filum terminale. Ⅱ)Segments of Spinal Cord The spinal cord is consisted of 31 segments in corresponding to the rootlets of a pair of spinalnerves, viz. C8, T12, L5, S5, C01. Ⅲ)Two Enlargements cervical enlargement (C4~T1): associating with brachial plexus innervating upper limb. lumbosacrla enlargement (L2~S3): associating with lumbosacral plexus innervating lower limb Ⅳ)Fissure and Sulcus anterior median fissure posterior midian sulcus anterolateral sulcus----anterior root (motor fibres) posterolateral sulcus----posterior root (sensory fibres) Ⅴ)Corresponding Relation between Spinal Segment and Vertebrae Spinal segment Vertebra upper cervical (C1~4) lower cervical (C5~8) upper thoracic (T1~4) middle thoracic (T5~8) lower thoracic (T9~12) L1~5 S1~5 , C01 C 1~4 corresponding spinal segment-1 corresponding spinal segment-2 corresponding spinal segment-3 T10~12 L1 Such as: C6 spinal segment is at the level of C5 vertebra. Ⅱ. Internal Structure central canal: longitudinal canal on transverse section grey matter: meurons and nerve fibres white matter: fibrous tracts anterior horn: anterolaterally grey matter posterior horn: posterolaterally (butterfly-shaped core) lateral horn: laterally grey commissure: around central canal anterior funiculus: between andterior median fissure and anterolateral sulcus. white matter posterior funiculus: between poslerior median sulcus and posterolateral sulcus. lateral funiculus: between anterolateral and posterolateral sulcuses. anterior white commissure: anterior to grey commissure. Ⅰ)Grey Matter The grey matter of the spinal cord contains an enormous mumber of neurons of varying in size and shape. Cell collection with common cytological characteristics, whose axons can be followed to a common termination and subserve the same function, are referred to as nucleus. 1. Nuclei in anterior horn α-motor neuron----large multipolar neuron, innervating skeletal m. (extrafuasl fibres), producing contraction of muscle. γ-motor meuron----smaller neuron, innervating intrafusal fibres, regulating muscular tonus. medial group----presented in most segments of spinal cord, innervating skeletal m. of head and neck. lateral group----presented in cervical and lumbosacral enlargements, innervating skeletal m. of four extremities. 2. Nuclei in posterior horn intermediolateral column nuclei: preganglionic neurons of sympathetic n. presented in T1~L3 spinal segments. sacral parasympathetic nuclei: preganglionic neurons of parasympathetic n. presented in S2~4 spinal segments. 3. Nuclei in posterior horn genlatiniform substance: outer cap-like portion of head of posterior horn. posteromarginal nucleus: dorsal to gelatiniform substance, covering tip of posterior horn. proper nucleus: ventral to gelatiniform substance. dorsal (thoracic) nucleus: in base of posterior horn, well defined in C8~L1 spinal segments. 4. Cutoarchitectural lamination Laminal Ⅰ: correspond to posteromarginal nucleus. Laminal Ⅱ: gelatiniform substance. Laminal Ⅲ, Ⅳ: proper nucleus. Laminal Ⅴ, Ⅵ: base of posterior horn. Laminal Ⅶ: thoracic nucleus, intermediolateral column in intermedial zone. Laminal Ⅷ: base of anterior horn. Laminal Ⅸ: several distinct groups of somatic motor neurons----α, γ cell of anterior horn. Laminal Ⅹ: area surrounding central canal. Ⅱ)White Matter In general, tract of fasciculus indicates the functional fibre bundles having the same origin, course and termination. asending tracts----from spinal cord to different segments of brain. descending tracts----from different segments of brain to spinal cord. proper tracts----from spinal cord to spinal cord (short ascending and descending tracts), with anterior and posterior rootlets, completing intrasegment and intersegment reflex. 1. Ascending tracts 1) Gracile fasciculus and cuneate fasciculus Gracile fasciculus origin termination location function Cuneate fasciculus spinal ganlia below spinal ganglia above T4 spinal segment T4 spinal segment gracile nucleus cuneate nucleus inmedulla oblongata inmedulla oblongata medial part of lateral part of posterior funiculus posterior funiculus conscious proprioceptive sensation, and fine of discriminating tactile in muscles, tendon, joint and skin. 2) Posterior and anterior spinocerebellar tracts Lateral spinocerebellar tract location Anterior spinocerebellar tract posterolateral periphery of lateral funiculus thoracic nucleus anterolateral periphery of lateral funiculus origin intermedial zone (Lamina Ⅴ~Ⅶ) termination cerebellar cortex cerebellar cortex through inferior cerebellar through superior function unconscious proprioceptive sensation, touch and pressure sensation of skin 3) Spinothalamic tract Posterior spinothalamic tract Anterior spinothalamic tract location lateral funiculus, anterior funiculus medial to anterior spinocerebellar tract origin proper nucleus of posterior horn (Lamina Ⅰ, Ⅵ, Ⅴ) termination ventral posterolateral nucleus in dorsal thalamus function apin and thermal sense touch and pressure sense 2. Descending tracts 1)Corticospinal tracts location Lateral corticospinal tract Anterior corticospinal tract media to posterior spinocerebellar tract bothe sides of anterior median fissure in lateral funiculus in anterior funiculus origin precentral gyrus and other cerebral cortex course crossed fibres uncrossed fibres termination motor cells of anterior horn of spinal cord function voluntary movements 2) The other descending tracts Location Function rubrospinal tract ventral to lateral corticospinal tract in lateral funiculus vestibulospinal anterior funiculus tact testospinal tract anterior funiculus medal longitudinal fasciculus reticulospinal tract anterior funiculus anterior and lateral funiculus facilitating fexor motor neurons increasing extensor muscle tone responsing to visual and auditory stimuli. banlance reflex regulating visceral activity and muscular tone Ⅲ. Function fo the Spinal Cord 1. Conduction of excitation. 2. Reflexing activity. 3. Connecting trunk and extremities through 31 pairs spinal nerves. Section 2 The Brain It is deivided into four principal areas: the brain stem, cerebellum, diencephalons and telecephalon. Ⅰ. External Features of Brain Stem The brain stem consists of three parts, from below upwards, the medulla oblongata, pons and midbrain. Its upper border is optic tract, lower border is foramen magum. Ⅰ)External Features of Medulla Oblongata. 1. Ventral surface pontomedullary groove: upper border of medulla oblongata. anterior median fissure: continuing with that of spinal cord. pyramid: formed by corticospinal tract. decussation of pyramids: formed by crossing fibres. olive: posterolateral to pyramid (inferior olivary nucleus). anterolateral sulcus: CN Ⅻ emerging from it. posterior olivary sulcus: dorsal to olive, from above downwards, CN Ⅸ, Ⅹ, Ⅺ emerging from it. 2. Dorsal surface The superior part of the dorsal surface forms the lower half of the floor of the fourth ventricle. gracile tubercle: an elongated swelling produced by gracile nucleus. cuneate tubercle: cuneate nucleus. inferior cerebellar peduncle: superolateral to cuneate tubercle formed by fibres entering cerebellum. Ⅱ)External Features of Pons 1. Ventral surface pontomedullay sulcus: from medial laterally, CN Ⅵ, Ⅶ, Ⅷ attaching on it. basilar sulcus: shallow groove for basilar a. basilar part: ventral surface bulges forwards and shows mumerous small transverse tidges. middle cerebellar peduncle: a compact mass joining with basilar part. root of CN Ⅴ: between basilar part and middle cerebellar peduncle. 2. Dorsal surface The dorsal surface of the pons forms the upper half of the floor of the fourth ventricle. superior cerebellar peduncle: foming lateral wall of the fourth ventricle. anterior medullary velum: a delicate lamina of white matter connecting two superior cerebellar peduncle, CN Ⅳ emerging from it . Ⅲ)Rhomboid Fossa The floor of the fourth ventricle is rhomboidal in shape, named rhomboid fossa. It si formed by the dorsal surface of both superior part of the medulla oblongata and the pons. lower border: gracile tubercle, cuneate tubercle, and inferior ferebellar peduncle. upper boder: superior cerbellar peduncle. lateral angle: lateral recess curving ventrally. medullary striae: from lateral angle to median sulcus, dividing medulla oblongata. median sulcus: longitudinally limiting sulcus: lateral to median sulcus. medial eminence: between two sulcuses above. vestibular area: triangular area lateral to limiting sulcus, overlying nucleus of vestibular n. acoustic tubercle: on lateral angle of vestibular trigone, overlying posterior cochlear nucleus. hypoglossal trigone: on medial eminence below medullary striae, overlying hypoglossal nucleus (superomedially). vagal trigone: inferolaterally, overlying dorsal vagal nucleus. postrema and locus ceruleus facial colliculus: a round swelling on medial eminence above medullary striae, overlying abducent nucleus. Ⅳ)The Fourth Ventricle It lies behind the pons and the upper half of the medulla oblongata, and in front of the cerebellum. The roof is toward the cerebellum, and the floor is rhomboid fossa. This ventricle contains cerebrospinal fluid, which communicates with midbrain aqueduct and central canal. superior cerebellar peduncles anterior part anterior medullary velum roof posterior medullary velum posterior part choroids tela of the fourth ventricle highly vascular tufts of pia matter, producing cerebrospinal fluid. three apertures median aperture: above tip of inferior angle of rhomboid fossa. ↓ subarachnoid space two lateral apertures: on tip of each lateral recess. Ⅴ)External Features of Midbrain It is a short part of brain stem, located between the optid tract of diencephalons above and the upper margin of pons below. Midbrain aqueduct passes through its centre. 1. Ventral surface cerebral peduncles: formed by descending fibres. interpeduncular fossa: a deep depression, CN Ⅲ emerging from the medial of it. 2. Dorsal surface superior colliculus: (visual reflex centre) brachium of superior Quadrigeminal body: colliculuslateral geniculate body inferior colliculus: (audiroty reflex centre) brachium of inferior colliculusmedial geniculate body Ⅱ. Arrangement of Cranial Nerve Nuclei in Brain Stem The cranial nerve nuclei are located in the dorsal portion of brain stem. They arrange as following from midline to lateral: Somatic motor nucleivisceral motor nucleivisceral sensory nucleisomatic sensory nuclei. In the brain stem, the limiting sulcus divides sensory and motor cranial nerve nuclei. The cranial nerve motor nuclei are medial to the limiting sulcus, and the cranial nerve sensory nuclei are lateral to the limiting sulcus. The functional components of cranial nerve nuclei are: 1. Somatic motor nuclei (general) oculomotor nucleus in midbrain trochlear nucleus abducent nucleus----in pons hypoglossal nucleus----in medulla oblongata 2. Special visceral motor nuclei motor trigeminal nucleus----in pons facial nucleus----in pons ambiguous nucleus in medulla oblongata accessory nucleus 3. General visceral motor nuclei parasympathetic mucleus of oculomotor nerve----in midbrain superior salivatory nucleus----in pons inferior salivatory nucleus in medulla oblongata dorsal vagal nucleus 4. Visceral sensory nuclei (general and special) Solitary nucleus-in pons and medulla oblongata 5. General somatic sensory nuclei trigeminal mesencephalic nucleus----in midbrain trigeminal pontine nucleus----in pons trigeminal spinal nucleus----in pons and medulla oblongata 6. Special somatid sensory nuclei vestibular nucleus in pons and medulla oblongata cochlear nucleus Ⅲ. Internal Structure of Medulla Oblongata The medulla oblongata can be divided into two parts, the upper and lower. The structures of the lower part are almost the same as those in spinal cord, but the strutures in the upper part are changed. 1. Edcussation of pyramids 2. Decussation of medial lemniscus 3. Appearance of inferior olivary nucleus and inferior cerebellar peduncle 4. Enlargement of central canal to form the fourth ventricle floor Ⅰ)Decussation of Pyramids corticonuclear tract: hypoglossal nucleus and lower part of facial nucleus receive the fibres only from contralateral corticonuclear tract. pyramids tract ---------------lateral corticospinal tract crossed corticospinal tract ---------------anterior corticospinal tract uncrossed Ⅱ)Decussation of Medial Lemniscus ipsilaterally Gracile and cuneate fascidulus----------------gracile and cuneate nucleus ( in medulla sending out fibres oblongata) --------------------decussation of medial lemniscusmedial lemniscusdorsal thalamus. Ⅲ)Inferior Olivary Nucleus and Infeior Cerebellar Peduncle olivocerebellar tract inferior cerebellar peduncle posterior spinocerebellar tract Ⅳ)Nuclei of Cranial Nerves 1. Hypoglossal nucleus It is located in both sides of the midline, underneath the hypoglossal trigone. The mucleus only receives the contralateral fibres from corticonuclear tract, and innervates the muscle of tongue. 2. Nucleus of accessory neve medullary partlower end of anbiguous nucleuscranial rootinnervating muscles of larynx and pharynx. spinal partfrom anterior horn of the upper cervical spinal cordspinal rootinnervating sternocleidomastoid m. and trapezius m. 3. Nuclei of vagal nerve 1) Dorsal vagal nucleus: located underneath vagal trigone, lateral to hypoglossal nucleus; innervating many cervical, thoracic and abdominal viscera. 2) Solitary nucleus: located dorsolateral to dorsal vagal nucleus; trceiving the fibres from all cervical, thoracic and abdominal mucous membrane. 3) Ambiguous nucleus: placed deeply in reticular formation; giving rise to the fibres to pharyngeal and laryngeal muscles. 4) Trigeminal spinal nucleus: lying on medial side of spinal tract; receiving impulse from posterior wall of external acoustic meatus. 4. Nuclei of glossopharyngeal nerve 1) Ambiguous nucleus: giving rise to the fibres to stylopharyngeal m. 2) Solitary nucleus: srceiving impulse from pharynx, auditory tube and posterior 1/3 of tongue (general visceral sense and gustatory sense). 3) Infeiror salivatory nucleus: to parotid gland. 4) Trigeminal spinal nucleus: collecting the fibres from skin of ear. Ⅳ. Internal Structure of Pons dorsal portion----pontine tegmentum two parts ventral portion----basilar portion The anterior margin of the trapezoid body is the boundary zone between the ventral and dorsal portion. The muclei of CN Ⅴ, Ⅵ, Ⅶ, Ⅷ are tound in pons. Ⅰ)Basilar Portion 1. Pyramidal tract corticospinal tract corticonuclear tract 2. Corticopontine tract: arising from the cells in frontal, parietal, temporal and occipital regions of cerebral cortex; and terminating in pontine nuclei ispilaterally. 3. Pontine nuclei: comprising all the masses of neurons scattered on this part; the fibres from these nuclei form middle cerebellar peduncle. They relay impulses from the cerebral cortex to the cerebellum. Ⅱ)Pontien Tegmentum 1. Cochlear nuclei (Dorsal and ventral cochlear nuclei): located on lateral surface of inferior cerebellar peduncle; concerning with hearing. sending out fibres Fibres from cochlear n. dorsal and ventral cochlear nuclei------------------------crossing to turning upward opposite sidetrapezoid body--------------------lateral lemniscusinferior colliculusmedial geniculate bodycerebral cortex. 2. Vestibular nuclei: four in number (inferior, superior, medial an lateral); underneath vestibular trugone; concerning with equilibrium sense. sending out fibres vestibulospinal tract Fibres from vestibular n. vestibular nucleus------------------- medial longitudinal tract the fibres to cerebellum 3. Nuclei of facila nerve 1) Facial nucleus: lying on dorsolateral to superior olive nucleus; innervating muscles of facial expression. upper part: receiving fibres from corticonuclear tract of both sides;innervating nucleus muscles above palpebral fissure. lower part: receiving fibres from corticonuclear tract of opposite side only;innervating muscles below palpebral fissure. 2) Superior salivatory nucleus: in the lateral of reticular formation; controlling the secretion of submandibular gland, sublingual gland, lacrimal gland and glands in mucous membrane of nose and mouth. 3) Solitary nucleus: concerning with the taste in anterior 2/3 of tongue. 4. Abducent nucleus: located underneath facial colliculus; innervating lateral rectus m. 5. Nuclei of trigeminal nerve 1) Motor trigeminal nucleus: located medial to rootlet of trigeminal n. and dorsolateral to reticular formation; innervating m. of mastication. 2) Trigeminal pontine nucleus: lying lateral to motor trigeminal nucleus; conceying impulse of touch sense from skin and mucous membrane of face and forehead. 3) Trigeminal spinal nucleus: a continuation of trigeminal pontine nucleus; conveying the impulse of pain and thermal sense in skin and mucous membrane of face and forehead. 4) Trigeminal mesencephalic nucleus: lying near lateral margin of central grey matter; conveying proprioceptive impulses from teeth, hard palate, m. of mastication, and joint capsules. Ⅴ. Internal Structure of Midbrain tectum----superior and inferior colliculus central grey matter ascending tract tegmentum black substance reticular formation (substantia nigra) red nucleus cerebral peduncle superior cerebellar peduncle pyramidal tract base of cerebral peduncle corticonuclear tract Ⅰ)Tectum 1. Superior colliculus: consisting of several layers of grey and white matter, a visual reflex centre. Occipital cortex superior colliculustectospinal tractmotor nucleus in brain stem, Retinaoptic tract anterior horn of spinal cordresulted in movements of head and eyes in response to visual and auditory stimulus. 2. Inferior colliculus: nucleus of inferior colliculus, auditory reflex centre. Cochlear nucleus inferior colliculusbrachium of inferior colliculusmedial geniculate Lateral lemniscus bodysuperior colliculustectospinal tractmotor nucleus in brain stem and spinal cordreflex in response to auditory stimulus. Ⅱ)Tegmentum 1. Central grey matter 1) Nuclei of oculomotor nerve oculomotor nucleus: at the level of superior colliculus; comprising paired lateral and single central nuclei; innervating all xtraocular m., except lateral rectus m. and superior oblique m. accessory oculomotor muclei (Edinger-Westphal): dorsomedial to oculomotor nucleus; giving rise to preganglionic parasympathetic fibres to ciliary ganglion (synapse); then sending out postganglionic fibres to ciliary m. and sphincter m. of pupil. 2) Trochlear nucleus: dorsal to medial longitudinal fasciculus; their fibres decussating completely in anterior medullary velum; innervating superior oblique m. 2. Red nucleus: ovoid mass in centre of tegmentum and dorsomedial to substantia nigra. Cerebral and cerebellar cortexred nucleusrubrospinal tractfacilitating flexor motor neurons. Ⅲ)Substantia Nigra A lamina of grey matter containing numerous, deeply pigmented nerve cells; lying between tegmentum and base of cerebral peduncle; extending through the whole length of midbrain and subthalamic region; grat development in man. Ⅳ)Base of Cerebral Peduncle It is the most ventral part of midbrain. frontopontine tract (medial 1/5) corticopontine tract parietopontine occipitopontine tract (lateral 1/5) temporopontine pyramidal tract corticospinal tract (middle 3/5) corticonuclear tract Ⅵ. Reticular Formation in Brain Stem It has long been recognized that scattered among the more conspicuous fibre bundles and nuclei of the brain stem are extensive field of intermingled grey and white matter collectively termed the reticular formation. Ⅶ. Cerebellum The cerebellum lies in the posterior cranial fossa, and is connected with the dorsal surface of brain stem by three cerebellar peduncles (superior, middle and inferior). It consists of two cerebellar hemispheres joined by a narrow median strip, the cerebellar vermis. Ⅰ)Subdivision of Cerebellum 1. Three lobes depending on the groove and fissure on its surface. flocculi (flocculus) flocculonodular lobe nodule (inferior surface) peduncle of flocculi anterior lobe (prior to primary fissure) posterior lobe (between primary fissure and posterolateral fissure) Three parts on its development and connection of afferent fibres. archicerebllum: viz. flocculonodular lobe, the oldest part; relating to vestibular nerve and nuclei; maintaining equilibrium. paleocerebellum: including anterior lobe, pyramid of vermis and uvula of vermis in posterior lobe; receiving fibres from anterior and posterior spinocerebllar tracts; regulating muscular tone. neocerebellum: the newest and largest part; including posterior lobe except pyramid of vermis and uvula of vermis; connecting with cerebral cortex through middle cerebellar peduncle; coordinating skilled movements initiated at cortical level. Cerebellar tonsils are two elevated masses on both sides of the uvula of vermis, nearby the foramen magnum. Ⅱ)Internal Structures of Cerebellum 1. Cerebellar cortex: It is a superficial grey matter, which surrounds the white matter called medullary body. 2. Cerebellar nuclei dentate nucleus: the largest one close to vermis. emboliform nucleus medial to dentate nucleus. globose nucleus fastigial nucleus: mear midline above roof of the fourth ventricle. Ⅲ)Fibrous Connection 1. Vestibulocerebellum (Archicerebellum) inferior cerebellar peduncle Vestibular nucleus of merves--------------------------------------archicerebellum---------------efferent fibre brain stem ---------------- inferior vestibular nucleusvestibulospinal tract. fastigial nucleus---------------------- cerebellar peduncle reticular formationreticulospinal tract. 2. Spinocerebellum (Paleocerebellum) superior and inferior Anterior and posterior spinocerebellar tract-----------------------------paleocerebellum-----cerebellar peduncle inferior cerebellar peduncle vestibular nucleus. fastigial nucleus-------------------------------- efferent fibres ---------------------- reticular formation. emboliform nucleus superior cerebellar peduncle ------------------------------------------------------ globose nucleus red nucleusrubrospinal tract. --------------------- reticular formationreticulospinal tract. 3. Pontocerebellum (Neocerebellum) middle cerebellar piduncle Corticopontil tractpontil nucleus---------------------------------neocerebellum----------------efferent fibres superior cerebellar peduncle --------------------dentate nucleus------------------------------------ventrolateral nucleus of dorsal (decussation) thalamussomatomotor area. Ⅷ. Diencephalons The diencephalons is almost entirely surrounded by the hemispheres of the cerebrum, and consists of five parts, viz. the epithalamus, thalamus (dorsal thalamus), hypothalamus, subthalamus, metathalamus. Ⅰ)Esternal Features of Diencephalon 1. Dorsal thalamus (Thalamus) They are two oval grey masses. The third ventricle is a space just between two dorsal thalamus. anterior tubercle of thalamus: amarrow eminence in anterior end of dorsal surface. pulvinar: elevation in posterior end. hypothalamic sulcus: from interventricular foramen to midbrain aqueduct, us a division between thalamus and hypothalamus. intermediante mass of dosal thalamus: trey matter connecting two thalamus, dorsal to hypothalamic sulcus. medullary stria and terminal stria 2. Metathalamus It lies inferolateral to pulvinar. brachium of inferior colliculus medial geniculate body-----------------------------------inferior colliculus (auditory sense) brachium of superior colliculus lateral geniculae body --------------------------------------superior colliculus (visual sense) 3. Epithalamus It lies around the roof of the third ventricle. medullary stria of thalamus: a longitudinal fibrous tract between dorsal and medial surface of thalamus habenular trigone habenular commissure: between two habenular trigone. pineal body: commecting habenular commissure posteriorlly. posterior commissure: below habenular commissure. 4. Hypothalamus It is situated below hypothalamic sulcus, and forms the side wall of the lower part of the third ventricle. anterior optic chiasmoptic tract (terminal lamina) ↓ cinereous tuberinfundibulumhypophysis posterior mammillary body 5. The third ventricle It is a median sagittal fissure just between two dorsal thalamus. anterior: terminal lamina posterior: passing to midbrain aqueduct roof: choroids tela, passing to lateral ventricle through interventricular foramen. floor: mammillary body, cinereous tuber, infundibulum, optic chiasm. Ⅱ)Internal Structures of Diencephalon 1. Dorsal thalamus and metathalamus Dorsal thalamus is an ovary grey mass medial to the internal capsule and lateral to the third ventricle. 1) Internal medullary lamina “Y” of thalamus anterior nuclear group medial muclear group (dorsomedial nucleus) dorsolateral nucleus dorsal layer posterolateral nucleus pulvinar lateral ventral anterior nucleus nuclear group ventral lateral nucleus ventral layer ventral ventral posterolateral nucleus (VPL) posterior nucleus ventral posteromedial nucleus (VPM) 2) Nucleus median nucleus interalaminar nucleus special relay nucleus: ventral layer of lateral nuclear group, medial and lateral geniculate bodies. association nucleus: medial nuclear group, dorsal layer of lateral nuclear group, anterior nuclear group. 3) Special relay mucleus ①Ventral anterior and ventral lateral nuclei They connect the xomatic motor area of cerebral cortex with cerebellar cortex. ②Ventral posterior nucleus medial lemniscus ventral paosterolateral nucleus: receiving spinothalamic tract trigeminal lemniscus ventral posteromedial nucleus: receiving gustatory fibres ③Medial and lateral geniculate bodies They are the relay nuclei of auditory and visual pathways. 2. Enpithalamus habenularnucleus 3. Subthalamus subthalamic nucleus red nucleus substantia nigra 4. Hypothalamus supraoptic nucleus: dorsal to optic chiasm. paraventricular nucleus: close to the third ventricle . nucleus of mammillary body: in mammillary body. acruate (infundibular) nucleus: near infundibulum. Ⅸ. Telecephalon The telecephalon comprises mainly two large cerebral hemispheres, which are almost completely separated by the longitudinal cerebral fissure. At the bottom of this fissure, there is a large bundle of transverse fibres, the corpus callosum, which crosses between the two hemispheres. The transverse cerebral fissure intervenes between the hemispheres and the cerebellum. cerebral cortex----grey matter basilar nucleus medullary centre---white matter lateral ventricle gyrus (gyri): upfolds on surface of hemisphere. fissures (sulcus or sulci): downfolds on surface of hemisphere. Ⅰ)External Features of Telecephalon superolateral surface surfaces medial surface in ferior (basilar)surface lateral sulacus sulci or fissures central sulcus parieto-occipital sulcus preoccipital notch frontal lobe parietal lobe lobes occipital lobe temporal lobe insula 1. Superolateral surface 1) Frontal lobe precentral sulcus parallel central sulcus precentral gyrus: between precentral and central sulcus superior and inferior frontal sulcus: prior to precentral sulcus parallel. superior, middle and inferior frontal gyrus 2) Parietal lobe postcentral sulcus: parallel to central sulcus. postcentral gyrus: between central and postcentral sulcus. interparietal sulcus: parallel to upper margin of hemisphere. superior parietal lobule supramarginal gyrus inferior parietal lobule angular gyrus 3) Temporal lobe superior and inferior temporal sulcus superior, middle, inferior temporal gyrus transverse temporal gyrus: two short gyri 4) Occipital lobe: irregular sulci and gyri. 5) Insula: There are shorter sulci. 2. Medial and inferior surface 1) Inferior surface of frontal lobe orbital sulcus orbital gyrus olfactory tract olfactory bulb olfactory trigone anterior perforated substance 2) Medial surface of parietal lobe patacentral lobule: extension of precentral and postcentral gyri. 3) Inferior and medial surface of temporal lobe occipitotemporal sulcus inferior medial occipitotemporal gyrus lateral occipitotemporal gyrus collateral sulcus rhinal sulcus parahippocampal gyrus: medial to collateral sulcus. medial uncus (unci) hippocampal sulcus dentate gyrus hippocampus 4) Medial surface of occipital lobe calcarine sulcus: arcuating posteriorly. cuneus lobe: between calcarine and parieto-occipital sulci. lingual gyrus: inferior to calcarine sulcus. 5) The other sulci and gyri sulcus of corpus callosum cingulate sulcus cingulate gyrus Ⅱ)Internal Structures of Telecephalon 1. Lateral ventricle It lies within the cerebral hemisphere, contains cerebrospinal fluid which passes to the third ventricle by the interventricular foramen. central part----lying in parietal lobe four anterior horn----extending into frontal lobe parts posterior horn----extending into occipital lobe inferior horn----extending into temporal lobe Choroid tela of lateral ventricle is within central part and infeior part. 2. Basilar nucleus The group of nucleus lies near the floor of the cerebral hemisphere, deep in the white matter. head caudate nucleus body meostriatum tail putamen corpus striatum lenticular nucleus pallid globe----paleostriatum claustrum: between insula cortex and lenticular nucleus. amyglaloid body: deep to uncus, anterior end of inferior hon of lateral ventricle. The function of corpus striatum is mainly concerned with the regulation of movement. 3. Cerebral cortex The cerebral cortex consists of archicortex, paleocortex and niocortex. Brodmann’s map was published in 1909 and consists of approximately 50 areas. 1) Somatic motor area Ⅰ ① Lying precentral gyrus and anterior portion of paracentral lobule. ② Receiving fibres from postcentral gyrus, ventrolateral nucleus, ventral anterior nucleus and ventral posterolateral nucleus. ③ Sending out fibres to form pyramidal tract. ④ Controlling voluntary movements of opposite side of body. ⑤ Characteristics: precise functional representation. representation appears inverted, such as head and neck inferiorly, following hand. Arm, trunk and thigh; but head and face are upright. size of cortical area for a particular part of body is determined by the functional importance and complexity fo the part. 2) Somatic sensory area Ⅰ ① Lying postcentral gyrus and posterior portion fo paracentral lobule. ② Receiving fibres from ventral posterior nucleus of dorsal thalamus for pain, thermal, tactile (touch), pressure, position, movement sense of opposite side of body. ③ Characteristics: inverted representation, but head and face are upright. precise functional representation. size of cortical area depends on functional important and sensitivity of the sense region. 3) Visual area ① Lying medial surface of occipital lobe around calcaren sulcus (adjacent portion of cuneus lobe and lingual gyrus). ② Receibing fibres from lateral geniculate body. ③ The left half of visual field is represented in the visual area of right hemisphere, and vice versa. 4) Auditory area ① Lying transverse temporal gyrus. ② Receiving fibres from medial geniculate body. ③ Representing bilaterally. 5) Language areas (Speech areas) The hemisphere relating to language function is termed dominant hemisphere, mostly in the left hemisphere because the right handed-persons are much more than the left ones. ① Motor speech area: in posterior portion of inferior frontal gyrus. ② Auditory speech area: in posterior portion of superior temporal gyrus. ③ Writng area: in posterior portion of middle frontal gyrus. ④ Visusl speech area: in angular gyrus. 4. Medullary centre of hemisphere 1) Commissural fibres They interconnect corresponding area in the opposite hemispheres. ① Corpus callosum It transverse the floor of cerebral longitudinal fissure and connects the cortex of two cerebral hemisphere. It includes four parts, viz. rostrum, genu, body, splenium, from before backwards. ② Anterior commissrue It is H-shaped arcuate fibrous bundles anterior to fornix. ③ Fornix and fornix commissure They are bilateral C-shaped white fibres originating from fimbria of hippocampus to nucleus of mammillary body. 2) Association fibres They interconnect different cortical area in the came hemisphere. uncinate fasciculus superior longitudinal fasciculus inferior longitudinal fasciculus 3) Projecting fibres They are referred to ascending and descending fibres connecting cerebral cortex and subcortical structures, such as spinal cord and brain stem. Internal capsule lies between caudate nucleus, dorsal thalamus medially and lentiform nucleus laterally, and is a “><” shaped layer of white matter. The division and its fibres are as following. ① Anterior limb of internal capsule It lies between caudate nucleus and lentiform nucleus. frontopontine tract containing anterior thalamic radiation (thalamocortical fibres) Posterior limb of internal capsule ②Posterior lim of internal capsule It lies etween thalamus and lentiform mucleus. Its three parts and passing fibres are: thalamolenticular part retrolenticular part corticospinal tract corticorubral tract centra thalamic radiation (thalamocortical tract, such as, trigeminal lemnisus, spinothalamic lemniscus, medial lemniscus) optic radiation parietopontine tract occipitopontine tract auditory radiation sublenticular part temporopontine tract ③Genu of internal capsule It is an angle area between anterior and posterior limbs, and contains corticonuclear tract. Ⅲ)Limbic System Limbic lobe includes septal area, cingulated gyrus, parahippocampal gyrus, hippocampus and dentate gyrus, which circle corpus callosum, almost becoming a ring. Limbic lobe adds cortical and subcortical structures closely related to it, such as amygdaloid body, septal area, sepptal nucleus, hypothalamus, epithalamus, anterior nucleus of dorsal thalamus, tegmentum of midbrain, then limbic system is formed. Section 3 The Conduction Pathways of the Brain and Spinal Cord They are the routes formed by chains of neurons, through which sensory awareness reaches the cerebral cortex and a motor response is initiated. The conduction pathways are commonly classified into ascending (sensory) and descending (motor) ones. Ascending pathways conduct impulse of various receptors of body to cerebral cortex or other higher centres of brain, and enable the individual to be conscious of his environment. They generally involve three orders of neurons. deep sense (proprioceptive sensation)----fine touch, pressure, position, movement, sense vibratory sense. superficial sense----pain, thermal, and simple touch. Descending pathways bring cerebral cortex and other subcortex into communication with effector tissues (such as muscles and glands), through anterior horn of spinal cord. Thus the body is able to respond to environment change. Two orders of neurons are usually involved. Ⅰ. The Conscious Deep Sensory Pathway muscles, tendons, peripheral processes ---------------------------------------------------------joints, skin. accompanying corresponding spinal nerve 1 2 central processes -------------------------------------------------------------------<·--------entering posterior funiculus of spinal spinal ganglia cord as a garcile and cuneate gracile and cuneate (first order neuron) fasciculus through dorsal root of nucleus spinal cord (second order neuron) 3 decussation of medial lemniscus × -----------------------------------<·-----------------------------------------ascending as medial lemniscus ventral posterolateral nucleus of dorsal thalamus (third order neuron) through posterior limb of internal capsule ①superior, middle part of postcentral gyrus ------------------------------------→ ②posterior part of paracentra lobule (thalamocortical tract) ③precentral gyrus Ⅱ)The Deep Sensory Pathway of Head and Face The exact route of this pathway is still unknown. Ⅱ. The Unconscious Deep Sensory Pathway Ⅰ)Posterior Spinocerebellar Tract 1 muscles, tendons, touch, peripheral process pressure receptors of lower limbs --------------------------------------------and lower part of trunk spinal nerve spinal ganglia 2 central posterior spinocerebellar tract ----------------<·---------------------------------→inferior cerebellar peduncle→ processes ipsilateral lateral funiculus thoracic nucleus →cortex of paleocerebellum Ⅱ)Anterior Spinocerebellar Tract 1 proprioceptive impulse of lower extremities and lower part of trunk peripheral process central ----------------------------------------------------spinal nerve processes spinal ganglia 2 anterior spinocerebellar tract ----<·-------------------------→superior cerebellar peduncle→cortex of paleocerebellum contralateral lateral funiculus × grey layer Ⅴ-Ⅶof lumbar enlargement Ⅲ. The Superficial Sensory Pathway of Trunk and Limbs 1 skin of peripheral processes central processes trunk and -----------------------------------------------------------------extremities accompanying entering spinal cord through dorsa roots corresponding spinal ganglia spinal nerve 2 3 ascending 1~2 spinal segments, then crossing × ------<·---------------------------------------------------------<·--------or cross one segment, spinothalamic tract cells of posterior ventral posterolateral nucleus horn (ⅠⅣⅤ) of dorsal thalamus (thalamocortical tract) superior, middle part of postcentral gyrus ----------------------------→ posterior limb of internal capsule posterior part of paracentral lobule A hemisection of spinal cord would cause loss of pain and temperature sensation on the opposite side of the body below the section, since the fibres of lateral spinothalamic tract are crossed. Because the gracile and cuneate fasciculus as well as spinothalamic tract have the same function in touch sense, and because the latter crosses over in spinal cord, the former uncrossed, a hemisection of the spinal cord ont result in complete loss of the sensations of touch. Ⅳ. The Superficial Sensory Pathway of the Head and Face 1 2 skin, mucous peripheral processes central processes of head ---------------------------------------------------------<·----and face trigeminal nerve entering pons semilunar ganglion trigeminal pontine nucleus trigeminal spinal nucleus 3 cross × ------------------------------<·--------------------------------------------trigeminal lemniscus posterior limb of internal capsule ventral posteromedial nucleus of dorsal thalamus ---------→lower part of postcentral gyrus Ⅴ. Optic (Visual) Pathway Visual field is the images of the objects in a visual space scope, which is divided into two part, the nasal half and temporal half. The retina itself also in cludes the nasal half and temporal half. 1 2 rod and peripheral central ----------------- -------------------<·------------optic nerve--- cone cells processes processes bipolar cells ganglion cells 3 ------optic chiasm---------------------------------optic tract---------<·---------nasal fibres of retina cross temporal fibres of retina uncross × lateral geniculate body optic radiation ----------------------------→both sides of calcarine sulcus (suneus lobe and lingual gyrus) posteror limb of internal capsule the impulse from upper half retina arrive the dorsal band of calcarine sulcus (cuneus lobe). The impulse from lower half retina arrive the ventral band of calcarine sulcus (lingual gyrus). The impulse from macula arrive the posterior portion of calcarine area. The impulse from peripheral retinal area end in the anterior portion of calcarine area. Light (Pupillary) Reflex partial fibres Cells of retina→optic nerve, optic chiasm, optic tract-----------------------<·-----through brachium of superior colliculus pretectal area oculomotor sphincter muscle of pupil ------<·-------------------------<·---------→ (regulating contraction of pupil) nerve ciliary muscle parasympathetic ciliary ganglion (regulating convexity of lens) oculomotor nucleus (Edinger-Westphal) Destruction (Inetrruption) analysis 1. Grossing fibres of optic chiasm: would cause blindness of two temporal visual field (bilateral or bitemporal hemianopsia). 2. Laeral (uncrossed) fibres of potic chiasm: would result in blindness of two nasal visual field (bimedial or binasal hemianopsia) . 3. Optic tract, lateral geniculate body, optic radiation, optic cortex on one side would cause blindness in the medial half visual field of one eye (destrcted side) and in the lateral half of the other one (undestructed side). 4. One optic nerve would result in blindness in the corresponding eye with loss of the papillary (light) reflex. Ⅵ. The Auditory Pathway 1 2 spiral organ peripheral central processes -----------------·--------------------------------<·------(Corti’s organ) processes cochlea nerve bipolar cells of dorsal and ventral cochlear spiral ganglion cochlear nuclei 3 trapezoid body brachium of inferior -------------------------------<·---------------------------------<·----------cross lateral lemniscus × colliculus inferior colliculus medial geniculate body -------------------------------→transverse temporal gyrus posterior limb of internl capsule Ⅶ. Pyramidal System Two orders of neurons are primarily involved, the upper and lower efferent neurons. upper efferent hypoglossal nucleus, lower portion neurons corticonuclear tract of facial nucleus are controlled by pyramidal tract genu of internal capsule opposite corticonuclear tract; ① ·--------------------others by bilateral corticonuclear tract. decussation of pyramid × precentral gyrus, anterior part corticospinal tract lateral corticospinal tract ② of paracentral lobule anterior part of crossing segment by segment (cortex) posterior limb of in spinal cord × Internal capsule anterior corticospinal tract ③ lower efferent neurons exteraocular m. masticatory m. -----------<·-----------→ facial m. ① laryngeal m. motor nucleus of cranial nerve pharyngeal m. lingual m. -----------------------<·----------------→ ② voluntary m. of trunk and extremities -----------------------<·----------------→ ③ cells of anterior horn of spinal cord Ⅷ. Extrapyramidal System Ⅰ)Concept and Composition It is a common name for all the structures which control voluntary muscle activities, except the pyramidal system. It mainly consists of cerebral cortex, corpus striatum, red nucleus, black substance, cerebellum, reticular formantion, vestibular nucleus. Ⅱ)Two Simple Descending Pathway 1. cerebral cortex pons thalamus cerebellum red nucleus spinal cord 2. cerebral cortex corpus striatum ----→thalamus subthalamus black substance reticular formation spinal cord Ⅲ)Two Systems and Four Tracts 1. Neostriatrum----pallid glaobe system 1) Cerebral cortex----corpus striatum----dorsal thalamus----cerebral cortex circle route. 2) Corpus striatum----black substance circle route 3) Pallid globe----subthalamus circle route 2. Corticopontocerebellar system cortex----pons----cerebellum----dorsal thalamus----cortex circle route 3. Four tracts Reticulospinal tract Rubrospinal tract Tectospinal tract Vestibulospinal tract Ⅳ)Function 1. Regulating muscular tone. 2. Maintaining the normal body posture (balance). 3. Coordinating muscular activities (precise motions). 4. Producing habitual and rhythmic movement. Section 4 The Meninges, Blood Vessels of Brain and Spinal Cord, as well as Cerebrospinal Circulation Ⅰ. The Meninges of Brain and Spinal Cord The brain and spinal cord are enclosed by three layers of membrane, the dura mater, arachnoid, pia mater, from external inwards. They protect and support the brain and spinal cord. Ⅰ)Dura Mater 1. Spinal dura mater It extends from the foramen magnum to the level of the second sacral vertebra, from which it tapers and forms a covering for the filum terminal of spinal cord. 1) Epidural space spinal dura mater lying between periosteum of vertebral canal containing: loose conjunctive tissue, lymphatic vessels, fat, venous plexus, especially root of spinal nerve. Being not continuous with cranial cavity upward. 2) Subdural space spinal dura mater between spinal arachnoid 2. Cranial dura matter 1) Double layers: periosteal, meningeal. 2) Loosely contacting with skullcap: closely attached to base of skull. 3) Falx and tentorium formed by meningeal layer. cerebral falx: extending into cerebral longitudinal fissure. cerebellar tentorium: between cerebral hemisphere and cerebellum. tentorial notch: anterior free margin of cerebellar tentorium. cerebellar falx: extending into two cerebellar hemisphere. 4) Dural venous sinus Lying between meningeal and peiosteal dura in some place. Characteristics: novalves, no smooth m., no contractivity. superior sagitaal sinus: lying in superior convex border of cerebral falx. inferior sagittal sinus: inferior concave border of cerebral falx. straight sinus: at the junction between cerebral falx and cerebellar tentorium. transverse sinus: in transverse sulcus, posterior margin of cerebellar tentorium. sigmoid sinus: in sigmoid sulcus. confluent sinus: at confluence of superior sagittal sinus and straight sinus. cavernous sinus: each side of sella turcica internal carotid a. intrasinus abducent n. (CN Ⅵ) oculomotor n. (CN Ⅲ) lateral wall of sinus trochlear n. (CN Ⅳ) ophthalmic n. (CN Ⅴ1) maxillary n. (CN Ⅴ2) superior petrosal sinus: insuperior angle of petrous portion of temporal bone. inferior perusal sinus: in inferior margin of posterior surface of petrous portion of temporal bone. The blood draning in dural venous sinus superior sagittal sinus occipital sinus inferior sagittal sinusstraight sinusconfluent transverse sigmoid internal jugular v. cavernous sinussuperior petrosal sinus inferior petrosal sinus Ⅱ)Arachnoid Arachnoid is atranslucent, delicate, avascular membrane between dura and pia mater. 1. Spinal arachnoid spinal arachnoid lying between subarachnoid space: spinal pia mater containing cerebrospinal fluid 2. Cranial arachnoid 1) Subdural space: between cranial dura mater and cranial arachnoid 2) Subarachnoid space ① Between cranial arachnoid and cranial pia mater ② Enlargement in some area subarachnoid cisterns cerebellomedullary cistern ③ Arachnoid granulation: especially in superior sagittal sinus, allowing cerebrospinal fluid to be reabsorbed into dura venous sinus. Ⅲ)Pia Mater The pia mater is a delicate vascular membrane, and rich in nerves. It is closely attached to the surface of brain and spinal cord. 1. Spinal pia mater Denticular ligament: is formed by spinal pia mater, which lies between dorsal and ventral roots of spinal nerve, and is attached to inner surface of spinal dura mater. 2. Cranial pial mater The cranial pia mater combines its capillaries and ependymal cells to form the choroids tela of the ventricle. Folds of choroids tela form choroids plexuses, which produce cerebrospinal fluid. Ⅱ. The Blood Vessels of the Brain and Spinal Cord Ⅰ)The Arteries of Brain internal carotid a. ----anterior 2/3 of cerebral hemisphere, anterior part two resource of diencephalon vertebral a. ----posterior 1/3 of cerebral hemisphere, brain stem, cerebellum, posterior part of diencephalon 1. Internal carotid artery Arising fom common carotid a. ascending to floor of skullcarotid canalcavernous sinusanterior clinoid process. 1) Posterior communicating a. ----communicating with posterior cerebral a. 2) Anterior choroidal a. ----forming arachnoid plexuses in lateral ventricle, supplying optic tract, internal capsule, base of cerebral peduncle and pallid globe. 3) Anterior cerebral a. anterior communicating a.----connecting two anterior cerebral a. supplying medial surface of cerebral hemisphere anterior to parietooccipital sulcus, inferior surface of frontal lobe. central branches----caudate nucleus, lenticular nucleus, internal capsule. 4) Middle cerebral a. ----supplying supralateral surface of hemisphere and insula. Central branch----caudate nucleus, lenticular nucleus, internal capsule. 2. Vertebral artery Arising from subcalvian a. transverse foramen of C1-6 vertebraeforamen magnumposterior cranial fossapontomedullary sulcusconfluence of two vertebral a. to form basilar a. basilar sulcussuperior border of pons. 1) Branches of vertebral a. ① Anterior and posterior spinal a. ----spinal cord. ② Posterior inferior cerebellar a. ----inferior surface of cerebellum, medulla oblongata. 2) Branches of basilar a. ① Anterior inferior cerebellar a. ----inferior surface of cerebellum. ② Labyrinthine a. ----inner ear. ③ Pontine a. ----pons. ④ Superior cerebellar a. ----upper part of cerebellum. ⑤ Posterior cerebral a. supplying base and medial surface of temporal lobe and occipital lobe. central branches----dorsal thalamus, medial and lateral geniculate body, hypothalamus, subthalamus. taking part in arachnoid plexuses of lateral and the third ventricles 3. Cerebral arterial circle (Willis circle) angerior cerebral a. (beginning prat) posterior cerebral a. anterior communicating a. posterior communicating a. internal carotid a. (terminal part) It encircles the optic chiasm, cinereous tuber, mammillary body over sella turcica. Ⅱ)The Veins of Brain superficial and deep group great cerebral v. Ⅲ)The Vessels of Spinal Cord anterior spinal a. v. posterior spinal a. v. Ⅲ. The Circulation of Cerebrospinal Fluid 1. Cerebrospinal fluid (CSF) is formed by choroids tela the in lateral, the third and fourth ventricles. 2. Circulation Lateral ventricleinterventricular foramenthe third ventriclemidbrain aqueductthe fourth ventriclemedian and lateral apertures of the fourth ventriclesubarachnoid spacesarachnoid granulationssuperior sagittal sinusinternal jugular v. PART ⅥTHE ENDOCRINE SYSTEM The endocrine system consists of the endocrine glands and endocrine tissues. The endocrine glands have no ducts, therefore they are known as ductless glands, which have a rich supply of blood vessles and pass their secretions derectly into the vascular channels. The secretions are called hormones, which have special effects on the body. Ⅰ. The Shape and Location of Thyroid Gland It likes “H” shaped body. lateral lobesattaching to lateral surface of lower part of larynx and upper part of trachea. (right and left) upper end: midpart of thyroid cartilage. -----→ Lower end: the sixth tracheal cartilage ring. isthmus: in front of 2~4 tracheal cartilage. Ⅱ. The Shape and Location of Parathyroid Gland They are four small yellowish ovoid or lentiform bodies. upper one pair: at the middle part of posterior border of thyroid gland. lower one pair: near inferior thyroid a. or at lower 1/3 of posterior part of thyroid gland. Ⅲ. The Shape and Location of Suprarenal Gland They are a pair of small yelloweish-brown bodies, lying on medial part of superior end of each kidney, and behind the peritoneum. right----triangular shape. left----crescent-like shape or semilunar shape Ⅳ. The Shape and Location of Hypophysis It is an ovary gland situated in the hypophyseal fossa of sphenoid body. adenohypophysis two parts neurohpophysis Ⅴ. The Shape and Location of Pineal Body It is an ovary body located in the posterosuperior to thalamus, attached the posterior part of the roof of the third ventricle by handle. Liu Zhiyu