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Comparing the Costs of Treating Prostate Cancer: Are There Significant Differences? Volume 13, Number 4 / January 30, 2002 The manuscript, “Comparing the Costs of Radiation Therapy and Radical Prostatectomy for the Initial Treatment of Early-Stage Prostate Cancer” appeared in the Journal of Clinical Oncology. The authors of the article are Lister Hill Scholar Jeffrey Burkhardt, PhD (UABHealth Services Administration), Mark S. Litwin, MD, MPH (University of CaliforniaLos Angeles) Christopher M. Rose, MD (Providence St. Joseph Medical Center), Roy J. Correa, MD (Virginia Mason Medical Center), Jonathon H. Sunshine, MD (American College of Radiology), Christopher Hogan, PhD (Direct Research, LLC) and James A. Hayman, MD (University of Michigan). Dr. Burkhardt can be reached at (205)934-1670 or [email protected] . "Yes," says Lister Hill Scholar Jeffrey Burkhardt and his colleagues. “Our results suggest that there are significant differences in the cost of early-stage treatment options for prostate cancer. To date, most studies have focused primarily on efficacy, health-related quality of life, or the cost of treating patients without regard to the type of treatment. Very few studies have examined the difference in cost between treatment strategies.” With prostate cancer the most commonly diagnosed cancer among men in the United States and the lack of a clinical consensus in favor of one treatment, cost factors are becoming an increasingly important issue in treatment decisions. Although the use of other treatments is growing, radical prostatectomy and external-beam radiation therapy remain the most common treatments for early-stage prostate cancer. “Any difference in cost between these options can be a significant factor,” says Burkhardt. To examine differences in cost, the researchers compared direct medical costs for the initial treatment period, defined as one calendar month before diagnosis to nine calendar months after diagnosis. The study population for the analysis included men age 65 or older, diagnosed with prostate cancer during 1992 and 1993, and receiving primary treatment with either external-beam radiation therapy or radical prostatectomy. The study found that the initial treatment costs were at least 23% greater for radical prostatectomy than for external-beam radiation. The average costs totaled $17,226 for radical prostatectomy compared to $14,048 for radiation therapy. “Because prostate cancer affects thousands of men per year, the costs associated with its treatment are of particular interest to policy makers and healthcare payers. Although issues other than cost are probably of more importance to individual patients, these results, indicating that radiation therapy is less expensive initially, remain important. Future research efforts should focus on costs beyond the initial treatment period, as well as changes in the management of early-stage prostate cancer over time.” Journal of Clinical Oncology, June 2002, pp. 2869-2875.