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MODELLO PER IL CURRICULUM VITAE INFORMAZIONI PERSONALI Nome Data di nascita Qualifica Amministrazione Incarico attuale Andrea Pace 2/8/1955 Medico Chirurgo, Neurologo IFO Responsabile ff SSD Neurologia Numero telefonico dell’ufficio 0652666067 Fax dell’ufficio 0652665068 E-mail istituzionale [email protected] TITOLI DI STUDIO E PROFESSIONALI ED ESPERIENZE LAVORATIVE Titolo di studio Laurea in Medicina e Chirurgia Altri titoli di studio e professionali Specializzazione in Neurologia Esperienze professionali ( incarichi 1988-1993 IRCCS S Lucia di Roma Assistente medico 1993 ad ottobre 2009 Istituto Nazionale Tumori Regina Elena –Neurologo Dal 5/10/2009 Istituto Nazionale Tumori Regina Elena Responsabile ff SSD Neurologia 2001 ad oggi Corso di Laurea in Scienze infermieristiche Università di Roma La Sapienza, Professore a contratto Inglese, buona conoscenza scritta e parlata ricoperti) Capacità linguistiche Capacità nell’uso delle tecnologie Altro ( partecipazione a convegni e seminari, pubblicazioni, collaborazioni a riviste, ecc. ed ogni altra informazione che il dirigente ritiene di dover pubblicare) Pubblicazioni su riviste recensite: 1-Pace A, Grassa C, Cavalletti C, Figa' Talamanca L: Complications of cerebral angiography. Statistical analysis of 1260 cases. Recenti Prog Med 1984 Feb;75(2):132-41 2-Bernardi S, Buttinelli C, Grasso MG, Millefiorini E, Pace A, Prencipe M, Fieschi C.: Evolution and severity markers in 233 MS patients. Riv Neurol. 1987 May-Jun;57(3):197-200. 3-Fieschi C, Argentino C, Lenzi GL, Fantozzi L, Sacchetti ML, Pace A, Rasura M, Bastianello S, Bozzao L, Zanette E, et al. Therapeutic window for pharmacological treatment in acute focal cerebral ischemia. Ann N Y Acad Sci. 1988;522:662-6 4-Buttinelli C, Pace A, Mauriello A, Sette G, Bonanno E, Zanette EM. B-mode echography in carotid pathology: correlation with morphology. Minerva Med. 1988 Aug;79(8):665-7 5-Giubilei F, Argentino C, Silvestrini M, Pace A, Rasura M, Di Piero V, Intiso D, Bastianello S, Paris L, Lenzi GL, et al.Prognostic factors in acute cerebral infarct. Minerva Med. 1988 Aug;79(8):637-40. 6-Pietrangeli A, Finocchiaro R, Pace A, Rinaldi M, Jandolo B. The effect of brain radiotherapy on the P3 component of ERP's. J Neurosurg Sci. 1990 Jul-Dec;34(3-4):327-8. 7-Jandolo B, Pietrangeli A, Pace A, Carapella CM, Finocchiaro R, Morace E. Brain-stem auditory evoked potentials in supratentorial brain tumors. Electromyogr Clin Neurophysiol. 1992 Jun;32(6):307-9. 8-Grasso MG, Pantano P, Ricci M, Intiso DF, Pace A, Padovani A, Orzi F, Pozzilli C, Lenzi GL. Mesial temporal cortex hypoperfusion is associated with depression in subcortical stroke. Stroke. 1994 May;25(5):980-5. 9-Pace A., Pietrangeli A., Bove L., Rosselli M., Lopez M., Jando B.:Neurotoxicity of antitumoral IL-2 therapy: evoked cognitive potentials a brain mapping. Ital J Neurol Sci 15: 341-346, 1994. 10-Jandolo B., Della Giulia M., Pace A., Pietrangeli A. et Neurophysiological examination of end-plate function in patients with lu cancer. Electromyogr clin neurophysiol 35: 247-250, 1995. 11-Pietrangeli A., Bove L., Innocenti P., Pace A.:Meningiti carcinomatose: aspetti clinici e decorso in 5 pazienti trattati con metotrexate endorachide. Riv. Neurobiologia, 41(5), 671-675,1995. 12-Pace A., Jandolo B: Taxoids neurotoxicity. Neurology 47, 615, 1996. 13-Pace A., Bove L., Nisticò C, et al : Vinorelbine neurotoxicity: clinical and neurophysiological findings in 23 patients. Journal of Neurology, Neurosurgery and Psychiatry 61,4: 409-411, 1996. 14-Jandolo B., Pietrangeli A., Pace A. et al: Electrophysiological testing in patients operated with the nerve sparing technique for bladder and prostate. J Exp Clin Cancer Res 15: 67-70, 1996. 15-Fuoco U, Scivoletto G, Pace A, Vona VU, Castellano V. Anaemia and serum protein alteration in patients with pressure ulcers. Spinal Cord. 1997 Jan;35(1):58-60. 16-Pace A., Bove L., Aloe A, et al: Paclitaxel neurotoxicity: clinical and neurophysiological study of 23 patients. Ital J Neurol Sci, 18:73-79, 1997 17-Pace A., Innocenti P., Bove L., et al: Epilessia come sintomo di esordio e nel decorso della malattia in 143 pazienti affetti da neoplasia cerebrale emisferica. Boll Lega It Epil, 99:269-270, 1997. 18-Pietrangeli A., Bove L., Innocenti P., Pace A. et al: neurophysiological evaluation of sexual dysfunction in patients operated for colorectal cancer. Clinical Autonomic Research 8,6:353-356, 1998 19-Pace A., Bove L., Innocenti P. et al: Epilepsy and gliomas: Incidence and treatment in 119 patients. J Exp Clin Cancer Res, 17,4: 479-482, 1998 20-Pace A. Assistenza domiciliare neuro-oncologica. Il progetto Qualità della vita dell’Istituto Regina Elena. Notiziario dei Comitati Gigi Ghirotti. 1999 21-C.Nistico’, C.Garufi, M.Milella, A.Vaccaro, AM D’Ottavio, A.Fabi, A.Pace, L.Bove, F.Tropea, A.Marsella, F.Izzo, RM D’Attimo, V.Ferraresi, S.De Marco, E.Terzoli: Weekly schedule of vinorelbine in pretreated breast cancer patients. Breast Cancer Research and Treatment 59: 223-229, 2000 22-S.De Santis. A.Pace, L.Bove, F.Cognetti, F.Properzi, M.Fiore, V.Triaca, A.Savarese, MD Simone, B.Jandolo, L.Manzione, L.Aloe: Patients Treated with Antitumor Drugs Dispalying Neurological Deficits Are Characterized by a Low Cinculating Level of Nerve Growth Factor Clinical Cancer Research 6, 90-95, January 2000 23-Bove L, Picardo M, Maresca V, Jandolo B, Pace A.: A Pilot study on the relationship between cisplatin neuropathy and Vitamin. E. J Exp Clin Cancer Res 2001; 20 (2): 277-280. 24-Pace A.: Cure palliative in Neuro-Oncologia. Notiziario dei Comitati Ghirotti. Luglio/Settembre 2001. 25-Pompili A, Caperle M, Pace A, Ramazzotti V, Raus L, Jandolo B, Occhipinti El: Quality of life evaluation in patients operated upon for cerebellar pilocytic astrocytoma. J Neurosurgery 96:229-234, 2002 26-Pace A et al: Un modello di assistenza continuativa per malati con tumore cerebrale. Rivista Italiana di Cure Palliative, vol 4 n 2, 2002. 27-Santanelli F, Tenna S, Pace A, Scuderi N: .Free flap reconstruction of the sole of the foot with or without sensory nerve coaptation. Plast Reconstr Surg. 2002 Jun;109(7):2314-22 28-Pace et al: Neuroprotective Effect of Vitamin E Supplementation in Patients Treated With Cisplatin Chemotherapy. J Clin Oncol. 2003 Mar 1;21(5):927-31. 2003. 29-Leonetti C, Biroccio A, Gabellini C, Scarsella M, Maresca V, Flori E, Bove L, Pace A, Stoppacciaro A, Zupi G, Cognetti F, Picardo M: Alphatocopherol protects against cisplatin-induced toxicity without interfering with antitumor efficacy. Int J Cancer. 2003 Mar 20;104(2):243-50. 30-Galie E, Pietrangeli A, Maschio M, Pace A, Vidiri A, Carosi M, Jandolo B.: Demyelinating disease in monoclonal gammopathy of undetermined significance. J Exp Clin Cancer Res. 2003 Jun;22(2):3379. 31-Pace A, Vidiri A, Galie E, Carosi M, Telera S, Cianciulli AM, Canalini P, Giannarelli D, Jandolo B, Carapella CM. Temozolomide chemotherapy for progressive low-grade glioma: clinical benefits and radiological response. Ann Oncol. 2003 ;14(12):1722-6. 32-Fabi A, Vidiri A, Carapella C, Pace A, Occhipinti E, Caroli F, Mirri A, Carlini P, Cognetti F: Bone metastasis from glioblastoma multiforme without central nervous system relapse: a case report. Anticancer Research 24 2004 33- Reni M, Mason W, Zaja F, Perry J, Franceschi E, Bernardi D, Dell'Oro S, Stelitano C, Candela M, Abbadessa A, Pace A, Bordonaro R, Latte G, Villa E, Ferreri AJ. Salvage chemotherapy with temozolomide in primary CNS lymphomas: preliminary results of a phase II trial. European Journal of Cancer 2004 Jul;40(11):1682-8 34-Pace A, Pompili A: Depression in Patients with High-grade Glioma: Results of the Glioma Project. Neurosurgery. 56(4):E873, April 2005. 35-Pace, Bove L, Jandolo B:Vitamin E and cisplatin neurotoxicity. Neurology. 2005 Aug 9;65(3):501-2 l 36-Fabi A,Salesi N,Di Cocco B, Vidiri A, Visca P, Pace A, Carapella C, De Paula U, Mirri A, Cognetti F: Choroid plexus carcinoma in the adult: is there a role for chemotherapy? J Exp Clin Cancer Res. 2005;24(3):493-6. 37-Pace, Bove L, Jandolo B:Vitamin E and cisplatin neurotoxicity. Neurology. 2005 Aug 9;65(3):501-2 l 38-Pace A: Diagnosi e trattamento delle Meningiti Neoplastiche. Medicina & terapia. Supplemento 2005. Edimes 39- A. Pace:Neuropatie da farmaci:criteri diagnostici e neuroprotezione. 2005;3:103-105. 40-Fabi A,Salesi N,Di Cocco B, Vidiri A, Visca P, Pace A, Carapella C, De Paula U, Mirri A, Cognetti F: Choroid plexus carcinoma in the adult: is there a role for chemotherapy? J Exp Clin Cancer Res. 2005;24(3):493-6. 41- PompiliA, Pace A, Occhipinti E: Subtemporal Transtentorial Approach. J Neurosurgery 104; 854-855, 2006 42 -Maschio M, Albani F,Baruzzi A,ZarablaA,Dinapoli L,Pace A,Pompili A,Carapella CM,Occhipinti E,Jandolo B: Levetiracetam therapy in patients with brain tumour and epilepsy. J Neurooncol 2006: 80(1):97-100 43-Guido Cavaletti, Stefano Jann, Andrea Pace, Rosaria Plasmati, Gabriele Siciliano, Chiara Briani, Dario Cocito, Luca Padua, Elisabetta Ghiglione, Mariagrazia Manicone, Giuditta Giussani, in the context of the Italian NETox Group: Multi-center assessment of the Total Neuropathy Score for chemotherapy-induced peripheral neurotoxicity. J Peripher Nerv Syst. 2006 Jun;11(2):135-41. 44-Pace A, Fabi A: Chemotherapy in neoplastic meningitis. Critical rewiev in Oncology/Hematology. 2006 45-Vidiri A, Carapella CM, Pace A, Mirri A, Fabi A, Carosi MA, Giannarelli D, Pompili A, Jandolo E,Occhipinti E, Di Giovanni S, Crecco M: Early post-operative MRI: correlation with progression free survival and overall survival time in malignant gliomas. Journal of Experimental and Clinical Cancer Research 2006:25 (2);177-182 46-G Cavaletti, B Frigeni, F Lanzani, M Piatti, S Rota, C Briani, G Zara, R Plasmati, F Pastorelli, A Caraceni, A Pace, M Manicone, A Lissoni, N Colombo, G Bianchi, C Zanna for the Italian NETox Group: The Total Neuropathy Score as a useful assessment tool for grading the course of chemotherapy-induced peripheral neurotoxicity: a comparison with the National Cancer Institute-Common Toxicity Scale. J Peripher Nerv Syst. 2007 Sep;12(3):210-5 47-M Reni, F Zaja, W Mason, J Perry, E Mazza, M Spina, R Bordonaro, F Ilariucci, M Faedi, G Corazzelli, P Manno, E Franceschi, A Pace, M : Candela, A Abbadessa, C Stelitano, G Latte and A J M Ferreri Temozolomide as salvage treatment in primary brain lymphomas British Journal of Cancer (2007) 96, 864-867. 48-Andrea Pace, Cecilia Nisticò, Federica Cuppone, Emilio Bria, Edvina Galiè,Giuliana Graziano, Guido Natoli, Isabella Sperduti, Bruno Jandolo, Francesca Calabretta, Silverio Tomao, Edmondo Terzoli:Peripheral Neurotoxicity of Weekly Paclitaxel Chemotherapy: A Schedule or a Dose Issue? Clin Breast Cancer. 2007 Apr;7(7):550-4 49-Andrea Pace: Intrathecal chemotherapy treatment of neoplastic meningitis from solid tumors using liposomal cytarabine: experience at the Istituto Regina Elena di Roma. Tumori, 93 (3);9-12:2007 50-A Pace:Supportive care and end of life issues. Rivista Medica. 2007,vol 13 n 4 51-Pace A. Rehabilitation in brain tumor patients. J Exp Clin canc Res,26,3,2007 52- Maschio M, Dinapoli L, Zarabla A, Pompili A, Carapella CM, Pace A, Giannarelli D, Occhipinti E, Jandolo B: Outcome and tolerability of topiramate in brain tumor associated epilepsy. J Neurooncol. J Neurooncol; 2007, 86(1): 61-70. 53- Nisticò C, Bria E, Cuppone F, Fornier M, Sperduti I, Carpino A, Pace A, Cognetti F, Terzoli E. Weekly epirubicin and paclitaxel with granulocyte colony-stimulating factor support in previously untreated metastatic breast cancer patients: a phase II study. Anticancer Drugs. 2007 Jul;18(6):687-92. 54-Andrea Pace, Cristiano Parisi, Maurizio Di Lelio. La Riabilitazione palliativa. Un progetto per l’assistenza e la qualità della vita dei malati neuro-oncologici. Riabilitazione Oggi. Anno XXIV, settembre 2007, 5253 55- Fabi A, Mirri A, Felici A, Vidiri A, Pace A, Occhipinti E, Cognetti F, Arcangeli G, Iandolo B, Carosi MA, Metro G, Carapella CM.Fixed doserate gemcitabine as radiosensitizer for newly diagnosed glioblastoma: a dose-finding study. J Neurooncol. 2008 Mar;87(1):79-84 56-Pompili A, Telera S, Pace A:Metastases to the cerebellum. Results and prognostic factors in a consecutive series of 44 operated patients. J Neuronc 2008 57- Maschio M, Albani F, Jandolo B, Zarabla A, Contin M, Dinapoli L, Fabi A, Pace A, Baruzzi A: Temozolomide treatment does not affect topiramate and oxcarbazepine plasma concentrations in chronically treated patients with brain tumor-related epilepsy. J Neurooncol. 2008 Jul 9 58-Andrea Pace, Cherubino Di Lorenzo, Lara Guariglia, B Jandolo, Carmine M Carapella, Alfredo Pompili: End of life issues in brain tumor patients. J Neurooncol. 2009 Jan;91(1):39-43 59-Anna Maria Di Nallo, Antonello Vidiri, Simona Marzi, Alessandra Mirri, Alessandra Fabi, Carmine Maria Carapella, Andrea Pace and Marcello Crecco: Quantitative analysis of CT-perfusion parameters in the evaluation of brain gliomas and metastases. Journal of Experimental & Clinical Cancer Research 2009, 28:38 60-Alessandra Fabi, Giulio Metro, Michelangelo Russillo, Antonello Vidiri, Carmine M Carapella, Marta Maschio, Francesco Cognetti, Bruno Jandolo, Maria A Mirri, Isabella Sperduti, Stefano Telera, Mariantonia Carosi and Andrea Pace: Treatment of recurrent malignant gliomas with fotemustine monotherapy: impact of dose and correlation with MGMT promoter methylation BMC Cancer 2009, 9:101 61- Maschio M, Dinapoli L, Vidiri A, Pace A, Fabi A, Pompili A, Carapella MC, Jandolo B.:The role side effects play in the choice of antiepileptic therapy in brain tumor-related epilepsy: a comparative study on traditional antiepileptic drugs versus oxcarbazepine J Exp Clin Cancer Res. 2009 May 6;28:60. 62 - Dinapoli L, Maschio M, Jandolo B, Fabi A, Pace A, Sperati F, Muti P.:Quality of life and seizure control in patients with brain tumor-related epilepsy treated with levetiracetam monotherapy: preliminary data of an open-label study. Neurol Sci. 2009 May 5. 63 - Cavaletti G, Cornblath DR, Postma TJ, Merkies IS, Argyriou A, Boogerd W, Briani C, Bruna J, Faber CG, Grisold W, Heimans JJ, Kalofonos H, Krarup-Hansen A, Koeppen S, Lauria G, Leandri M, Mielke S, Nobile-Orazio E, Pace A, Padua L, Plasmati R, Psimaras D, Ros T, Schenone A, Stragliotto G, Galimberti S, Valsecchi MG. CIPERINOMS Study Group: CI-PERINOMS: chemotherapy-induced peripheral neuropathy outcome measures study. J Peripher Nerv Syst. 2009 Jun;14(2):69-71. 64- Maschio M, Dinapoli L, Vidiri A, Pace A, Fabi A, Pompili A, Carapella MC, Jandolo B.: The role side effects play in the choice of antiepileptic therapy in brain tumor-related epilepsy:a comparative study on traditional antiepileptic drug versus oxcarbazepine. J Exp Clin Cancer Res. 2009 May 6;28:60. 1/12/2009