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Nursing Process Focus: Patients Receiving Fluconazole (Diflucan) Assessment Prior to administration • Obtain complete health history including allergies, drug history and possible drug interactions. • Assess for presence or history of cryptococcal meningitis, oropharyneal candidiasis, systemic candidiasis, vaginal candidiasis. Potential Nursing Diagnoses • Risk for Infection, related to ineffective response to drug therapy • Risk for Injury, related to dizziness secondary to drug therapy • Pain (headache), related to adverse effects of drug therapy • Imbalanced Nutrition: Less than Body Requirements, related to nausea and diarrhea secondary to side effects of drug therapy Planning: Patient Goals and Expected Outcomes The patient will: • Remain free of physical injury. • Remain pain free. • Maintain adequate nutrition. Implementation Interventions and (Rationales) *Monitor vital signs, especially temperature. (Temperature will help to determine the patient’s response to the medication.) *Monitor for development of GI distress. (Gastrointestinal distress may occur because 90% of the medication is absorbed from the GI tract but absorption of this medication is not affected by the presence of food.) *Monitor ALT, AST, alkaline phosphatase, and bilirubin. (This medication may cause increase in values of these tests.) Patient Education/Discharge Planning *Instruct patient to monitor temperature and report occurrence of fever to health care provider. *Advise patient to take medication with food to decrease gastrointestinal distress. Advise patient : • to abstain from alcohol while taking this medication. • to complete lab testing as proscribed. *Monitor BUN and serum creatinine. (There is a Advise patient: small chance of renal damage possibly related to • to increase fluid intake while on drug the long half-life and the excretion of the therapy. medication.) • to report changes in urinary output to *Monitor intake and output. Make sure patient health care provider. remains adequately hydrated during drug therapy. *Monitor the blood sugar of patients on oral *Advise diabetic patients to increase blood hypoglycemic medications (because of an glucose monitoring and notify health care increased risk of hypoglycemia.) provider of hypoglycemia. *Keep the bed in a low position and monitor the *Advise patient to rise slowly from a seated or patient for any central nervous system effects. lying position and take care while using stairs (Headache and dizziness may occur in some and steps. patients because of a reaction from the concentration of this medication in the CSF.) Evaluation of Outcome Criteria Evaluate the effectiveness of drug therapy by confirming that patient goals and expected outcomes have been met (see “Planning”).