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CASE 1: • • • • • • R.R.G 39, G2P1 (0-1-0-1), 25 1/7 weeks CC: watery vaginal discharge Past Medical: G1 – NSD at 33 weeks AOG Personal/Social History: U/R Family History: (+) Hypertension, Asthma, Diabetes Birth History • • • • • • Baby Boy Live, preterm Delivered via Normal Spontaneous Delivery 39 y/o (G2P2) (0202) 25 4/7 weeks AOG MT: 26 weeks, AGA Anthropometrics • • • • • BW 830g BL 32 cm HC 24 cm CC 21 cm AC 18 APGAR SCORE (1st minute) = 3 SIGN Heart rate Respiratory effort Muscle tone 0 Absent Absent Limp 1 Below 100 Slow, irregular Some flexion of extremities Grimace Response No to catheter response in nostril (tested after oropharynx is clear) Color Blue, pale Body pink, extremities blue 2 Over 100 Good, crying Active motion Cough or sneeze Completely pink Positive Pressure Ventilation APGAR SCORE (5th minute) = 6 SIGN Heart rate Respiratory effort Muscle tone 0 Absent Absent Limp 1 Below 100 Slow, irregular Some flexion of extremities Grimace Response No to catheter response in nostril (tested after oropharynx is clear) Color Blue, pale Body pink, extremities blue 2 Over 100 Good, crying Active motion Cough or sneeze Completely pink Positive Pressure Ventilation APGAR SCORE (10th minute) = 7 SIGN Heart rate Respiratory effort Muscle tone 0 Absent Absent Limp 1 Below 100 Slow, irregular Some flexion of extremities Grimace Response No to catheter response in nostril (tested after oropharynx is clear) Color Blue, pale Body pink, extremities blue 2 Over 100 Good, crying Active motion Cough or sneeze Completely pink Free Flow O2 Thermoregulation Admitting Impression • Extreme Prematurity, Very Low Birth Weight Sepsis Unspecified • UVC inserted • O2 support via nasal cannula at 2 lpm • Diagnostics: – – – – CBC, CRP Blood Culture Hgt CXR • Therapeutics: – IVF at TFR 80 – IV antibiotics (Ampicillin, Amikacin) – Aminophylline PROBLEMS • • • • • 1. Prematurity 2. Sepsis 3.. Respiratory (Pneumonia and Apnea) 4. Jaundice 5. Anemia Problem 1: Prematurity • Thermoregulation: – The patient was placed in an isollette and wrapped in plastic to keep thermoregulated. – Temperature maintained at 36.5-37.5C • Feedings: – Upon delivery patient was on NPO, IVF started at TFR 80 – Aminosteril started – On the 3rd day of life, NGT was inserted and patient was started on Glucose water then Breast milk Problem 2: Sepsis • Diagnostics: – CBC – CRP – Blood culture • Patient was started on the following medications: – Ampicillin – Amikacin Hgb Hct WBC Band Neu Lym Mon Eos Plt 116 35 19 02 6 2 CRP 0.04 Blood Culture: No growth (7 days) 80 16 261 Problem 3: Respiratory • Pneumonia in the left lower lung • UVC at level of T7 to T8 Start Cefotaxime Problem 3. Respiratory (Apnea) First hour of life Awake Active No desaturations T 37 HR 130 RR 49 O2 sats 97 Generalized Jaundice No alar flaring Good air entry Harsh breath sounds Regular cardiac rhythm Full pulses Prematurity Sepsis Unspecified Start Aminophylline 2nd day of life Awake Active Episodes of desaturations and bradycardia T 37 HR Less than 100 O2 sats 70s Generalized Jaundice No alar flaring Good air entry Harsh breath sounds Regular cardiac rhythm Full pulses Apnea of Prematurity Continue Aminophylline Stimulation during periods of apnea 11th day of life Awake Active Persistent desaturations T 37C HR less than 100 O2 sats 40s-50s Pink Minimal effort on respiration No alar flaring sounds Regular cardiac rhythm Full pulses Apnea Probably secondary to progressing Pneumonia or Electrolyte Imbalance Ambubagging EG7 Chest Xray O2 support pH 7.198 pCO2 74.4 pO2 80 HCO3 29 BE 1 SO2 92 Na 119 K 4.7 Ical 133 Hgb 82 Hct 24 Na correction with NaCl incorporation • Progressing Pneumonia with Consolidation 11th day of life Awake Active Persistent desaturations T 37C HR less than 100 O2 sats 40s-50s Pink Minimal effort on respiration No alar flaring sounds Regular cardiac rhythm Full pulses Apnea Probably secondary to progressing Pneumonia or Electrolyte Imbalance For intubation Mech Vent settings: FiO2 60 PIP 18 PEEP 4 RR 50 iT 0.45 Repeat CBC and EG7 Shift IV antibiotics to Meropenem pH 7.387 Hgb 91 pCO2 32.3 Hct 27 pO2 42.9 WBC 14.6 HCO3 19.4 Neutrophils 70 BE Lymphocytes 23 SO2 Monocytes 2 Eosinophils 0 Platelet 422 Cranial Ultrasound • Intraventricular and Germinal Matrix Hemorrhage (Grade II intracranial hemorrhage) 13th to 17th day of life Awake Active Episodes of desaturation T 37C HR 130 O2 sats 95-100% Pink Minimal effort on respiration No alar flaring sounds Regular cardiac rhythm Full pulses t/c Bronchopulmonary Dysplasia Mech Vent settings adjusted accordingly Start Dexamethasone Problem 4: Jaundice 2nd day of life Awake Active No desaturations T 37.1 HR 140 RR 49 O2 sats 96 Generalized Jaundice No alar flaring Good air entry Harsh breath sounds Regular cardiac rhythm Full pulses Prematurity Sepsis Unspecified Hyperbilirubinemia Unspecified Start double phototherapy Problem 4: Jaundice 4th day Awake Active T 37 HR 130 RR 50 O2 sats 98 Pink No alar flaring Good air entry Harsh breath sounds Regular cardiac rhythm Full pulses Prematurity Sepsis Unspecified Hyperbilirubinemia Unspecified, resolved Phototherapy discontinued Problem 6: Anemia 12th day of life T 36.5 HR 150 RR 53 O2 sats 95 Pale skin No alar flaring Harsh breath sounds Regular cardiac rhythm Full pulses Prematurity Sepsis Unspecified Apnea of Prematurity Anemia PRBC for transfusion Pre transfusion Hgb Hct 82 24 Hgb Hct Post 127 Transfusion 37 • Diagnosis: • Extreme Prematurity, Very Low Birth Weight, Sepsis Unspecified, Neonatal Pneumonia, Apnea of Prematurity, t/c Bronchopulmonary Dysplasia •THANK YOU