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Prescription writing Dr.Saeed Ahmed A prescription: A physician's order to prepare / to dispense a specific Tr -usually medication- for an individual patient. Rational prescribing: Like any other process in health care, writing a prescription should be based on a series of rational steps: 1- Make a specific diagnosis 2- Consider ! pathophysiologic implications of ! diagnosis 3- Select a specific therapeutic objective 4- Select a drug of choice 5- Determine ! appropriate dosing regimen 6- Devise a plan for monitoring ! drug’s action & determine an end point for therapy 7- Plan a program of patient education. In ! hospital setting, drugs are prescribed on a particular page of ! patient’s hospital chart called ! physician’s order sheet/ chart order. There are 3 common types of Rx : 1- Prescription in general practice 2- Hospital prescription for in-patients 3- Hospital prescription for an (external pharmacy). Parts of prescrition: Superscription: name, professional degree, contact no. address of ! prescriber, ! date when ! order is written. name, address & age of ! patient; & ! symbol Rx (an abbreviation for "recipe," ! Latin for "take thou." _ Inscription : ! body of ! Pres. containing ! name, strength of each drug, & dosage form of ! Tr. Subscription: quantity to be dispensed. ! directions to ! pharmacist, usually consisting of a short sentence: "make a solution," "mix & place into 10 capsules," or "dispense 10 tablets." Transcription : labeling of instruction to ! Patient, prescriber's signature. When writing ! drug name: - either generic name (nonproprietary name) is used. - OR ! brand name (proprietary name) - ! strength of ! medication should be written in metric units (Not apothecary). 1 gr = 60 mg 15 gr = 1 g 1 ounce (oz) by volume = 30 ml 1 tsp = 5 ml 1 tbsp= 15 ml 20 drops= 1 ml 2.2 ponds (Ib) = 1 kg. Principles for writing pres. for both controlled & uncontrolled drugs Prescribers should: ALWAYS write legibly in ink (clear writing) Use metric system (g, L) ALWAYS sign & date ! the prescription Precise Accurate Use precautions to remind patients about SE NEVER abbreviate drug names When writing ! INDIVIDUAL DOSE: for STRENGTHS >1g use grams for STRENGTHS <1g use milligrams e.g.100mg for STRENGTHS <1mg use micrograms e.g. 100 microgram (NEVER use 'µg') AVOID unnecessary decimal points e.g. use 300 mg NOT 0.3 g. Previous adverse pres./ allergies; ask for drug history or medical record Check other medication charts (anticoagulants, insulin) Specify time course; if ! drug is taken for a number of days/ continuously (course of antibiotic, antihypertensive/ antiparkinson drugs. As required medications Indication, frequency, minimal time interval btw doses & maximum dose in 24 hr period. ! instructions should be sufficient for a nurse to administer a drug accurately in ! hospital, or for a pharmacist to provide a patient e both ! correct drug & ! instructions on how to take it. Medication error is ! most common medical mistake. Prescription for uncontrolled drugs include: - date - identification of patient: name, hospital number, age, sex - name of ! drug - dose of ! drug - frequency of administration - route & method of administration - amount to be supplied - ! prescriber's signature. Controlled drugs: Substance, which may produce physical, psychological dependence / both Prescribed for not > than 2 weeks because sudden withdrawal may lead to withdrawal symptoms.. Classification of controlled substances. Based on estimated addiction liability Class Potenti Rationale for category & Rx rules -al for abuse Examples I High abuse potential No accepted medical use, All no research use forbidden, can Not be prescribed lack of accepted safety as drug Heroin, LSD (Lysergic Acid Diethylamide), marijuana II H Current accepted medical use but abuse may lead to severe physical/ psychic dependence Opioids as morphine, amphetamines III < class II Current accepted medical use. moderate or low potential for physical & high potential for psychologic dependence, No refills, Rx must be rewritten after 6 months Weaker opioids such as codeine, some amphetamine-like drugs IV < III Medical use is accepted. Limited / low potential for dependence Diazepam, phenobarbital, chloral hydrate etc Schedule V < IV Medical use is accepted. ! least potential for abuse cough syrups e codeine , antidiarrheal e diphenoxylate etc Schedules of Controlled Drugs: ! drugs are divided into 5 schedules: Schedule I Drugs in this schedule have no accepted medical use & have a high abuse potential. Ex. heroin, marijuana, LSD, etc. Schedule II Drugs in this schedule have a high abuse potential e severe psychic or physical dependence liability. Included are certain narcotic analgesics, stimulants, & depressant drugs. Ex. opium, morphine, codeine, methadone, cocaine, amphetamine. Schedule III Drugs in this schedule have an abuse potential < than those in Schedules I & II & include compounds containing limited quantities of certain narcotic analgesic drugs, & other drugs such as barbiturates. pentobarbital. Schedule IV Drugs in this schedule have an abuse potential < than those listed in Schedule III & include such drugs as barbital, phenobarbital, chloral hydrate, chlordizepoxide, diazepam, oxazepam etc. Schedule V Drugs in this schedule have an abuse potential < than those listed in Schedule IV & consist primarily of preparations containing limited quantities of certain narcotic analgesic drugs used for antitussive & antidiarrheal purposes. Rx for controlled drugs: Should not be typed & written by hand Written in ink Signed & dated Carry ! prescriber's full name, address & registration number State ! form of ! drug State ! total quantity of ! drug or ! number of doses units (10.0 mg i.e. ten milligrams) Not be refillable > than 5 times in a 6 months period for schedule III-IV-V Rx; No refilling for schedule II Rx. Abbreviation \ Meaning a.c. before meals p.c. After meal cap Capsules g gram h. hour mg milligram ml milliliter Bid Twice daily p.o. by mouth, orally p.r.n. when necessary q.d. once a day q.i.d. 4 times a day q.h. every hour q.2h. every 2 hours t.i.d. 3 times a day IA Intra-arterial IM Intramuscular IV intravenous Hs At bed time Cap Capsule Sup, supp suppository Susp suspension Tab tablet Stat D/C CD At once Discontinue Controlled drugs Computerized physician order entry (CPOE): is a process of electronic entry of physician instructions for ! tr of patients (particularly hospitalized patients) under his or her care. These orders are communicated over a computer network to ! medical staff (nurses, therapists, pharmacists, or other physicians) or to ! departments (pharmacy, laboratory or radiology) responsible for fulfilling ! order. CPOE advantages: - decreases delay in order completion, - reduces errors related to handwriting or transcription,?? - provides error-checking for duplicate or incorrect doses or tests, & - simplifies inventory & posting of charges.