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S. Arabzadeh, M.D. Deficit in voluntary motor or sensory function Preceded by conflicts or other stressors The gain is primarily psychological not social monetary or legal Ratio of women to men ◦ Range of 2/1 to 10/1 in adults ◦ Increased female predominance in children Women with conversion symptoms more likely to subsequently develop somatization disorder Incidence less than 1% of general population 5 to 15 % of psychiatric consultations in a general hospital Common age is adolescents and young adults Onset at any age, but most common in adolescent to early adulthood (rare before 10 years of age, or after 35, but reported as late as the ninth decade of life) Probability of occult neurological or other medical condition high with onset of symptoms in middle or old age. Motor symptoms Sensory deficits Most common symptoms ◦ Paralysis ◦ Blindness ◦ Mutism Sensory symptoms ◦ Anesthesia and paresthesia (extremities) ◦ Distribution of the neurological deficit inconsistent with either central or peripheral neurological disease (e.g. stocking-andglove anesthesia, and hemianesthesia beginning precisely along the midline) ◦ deafness, blindness, tunnel vision ◦ Unilateral or bilateral Intact sensory pathways by neurological exam (e.g. conversion disorder blindness: ability to walk around without collision or self-injury, with pupils reactive to light, and normal cortical evoked potentials.) Motor symptom: Abnormal movements (choreiform, tics, jerks) Gait disturbance Weakness Paralysis Motor symptoms Movements generally worsen with calling of attention Reflexes remain normal No fasciculations/muscle atrophy (except chronic conversion) Normal electromyography Seizure symptoms ◦ Pseudoseizures 1/3 of those with pseudoseizures have coexisting epileptic disorder Tongue biting, urinary incontinence, and injuries after falling can occur (although generally absent) Pupillary and gag reflexes retained No postseizure increase in prolactin concentration ◦ Depressive disorders (increased suicide risk) ◦ Anxiety disorders ◦ Somatization disorders ◦ Personality Disorders Medical and especially neurological disorders Psychoanalytic factor Repression of unconscious intrapsychic conflict Conversion of anxiety into a physical symptom Biological Factor Hypometabolism of dominant hemisphere Hypermetabolism of nondominant hemisphere Ruling out a medical disorder 25—50 % have neurological or nonpsychiatric medical disorder Can be resolved by suggestion LA BELLE INDIFFERENCE CONDITION TEST Tunnel vision Visual fields Profound monocular blindness Swinging flashlight sign (Marcus Gunn) Binocular visual fields Severe bilateral blindness “Wiggle your fingers; I’m just testing coordination.” Sudden flash of bright light “Look at your hand.” “Touch your index fingers.” CONDITION TEST Aphonia Request a cough Intractable sneezing Observe CONDITION TEST Coma Examiner opens eyes Ocular cephalic maneuver Syncope Head-up tilt test CONDITION TEST Anesthesia Map dermatomes Hemianesthesia Check midline Astasia-abasia Walking, dancing Paralysis, paresis Hand drop onto face Hoover test Check of motor strength Insight-oriented supportive or behavior therapy Relationship with a caring and confident therapist most important feature of the therapy Reassurance helping the patient verbalize distress simple behavioral interventions Presentation of the diagnosis avoid indirect and fragmentary discussion naming: non epileptic seizure Avoid mentioning ‘real’ or ‘unreal’ Validate the reality of events Present the result of the tests Cause of the disease We do not know the cause Symptoms have no clear physical cause Is not intentionally made Result from interaction between subconscious mind and body Role of stress Need of psychological interview Encourage the patient to acknowledge recent stresses Give positive reinforcement Take brief rest from stress before returning to usual activities Advise against prolonged rest or withdrawal from activities Symptoms usually resolve rapidly leaving no permanent damage Acute cases ◦ Reassurance/appropriate rehabilitation Resolution usually spontaneous Chronic cases ◦ Aggressive therapy of comorbid psychiatric illness ◦ Pharmacotherapy Anxiolytic or antidepressant medications ? ◦ Psychotherapy comorbid psychiatric condition SSRI Beta-blockers Analgesics Benzodiazepines psychological process by which one person may guide the thoughts, feelings or behaviour of another waking suggestions hypnotic suggestions Family therapy Cognitive behavior therapy problem-solving techniques reframing of distorted cognitive beliefs Counseling Group therapy Hypnosis Psychodynamic approaches Exploring intrrapsychic conflicts, and the symbolism of conversion symptoms ??? Good prognosis Acute onset Identifiable stressor Short interval between onset and treatment Paralysis Aphonia blindness 95% 20-25% remit spontaneously Recurrence 25 to 50% neurological disorders or nonpsychiatric medical conditions affecting the nervous system THANK YOU Any Question?