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S. Arabzadeh, M.D.    Deficit in voluntary motor or sensory function Preceded by conflicts or other stressors The gain is primarily psychological not social monetary or legal  Ratio of women to men ◦ Range of 2/1 to 10/1 in adults ◦ Increased female predominance in children  Women with conversion symptoms more likely to subsequently develop somatization disorder    Incidence less than 1% of general population 5 to 15 % of psychiatric consultations in a general hospital Common age is adolescents and young adults Onset at any age, but most common in adolescent to early adulthood (rare before 10 years of age, or after 35, but reported as late as the ninth decade of life)   Probability of occult neurological or other medical condition high with onset of symptoms in middle or old age.  Motor symptoms  Sensory deficits  Most common symptoms ◦ Paralysis ◦ Blindness ◦ Mutism  Sensory symptoms ◦ Anesthesia and paresthesia (extremities) ◦ Distribution of the neurological deficit inconsistent with either central or peripheral neurological disease (e.g. stocking-andglove anesthesia, and hemianesthesia beginning precisely along the midline) ◦ deafness, blindness, tunnel vision ◦ Unilateral or bilateral  Intact sensory pathways by neurological exam (e.g. conversion disorder blindness: ability to walk around without collision or self-injury, with pupils reactive to light, and normal cortical evoked potentials.)  Motor symptom: Abnormal movements (choreiform, tics, jerks) Gait disturbance Weakness Paralysis  Motor symptoms  Movements generally worsen with calling of attention  Reflexes remain normal  No fasciculations/muscle atrophy (except chronic conversion)  Normal electromyography  Seizure symptoms ◦ Pseudoseizures  1/3 of those with pseudoseizures have coexisting epileptic disorder  Tongue biting, urinary incontinence, and injuries after falling can occur (although generally absent)  Pupillary and gag reflexes retained  No postseizure increase in prolactin concentration ◦ Depressive disorders (increased suicide risk) ◦ Anxiety disorders ◦ Somatization disorders ◦ Personality Disorders  Medical and especially neurological disorders Psychoanalytic factor   Repression of unconscious intrapsychic conflict Conversion of anxiety into a physical symptom Biological Factor   Hypometabolism of dominant hemisphere Hypermetabolism of nondominant hemisphere  Ruling out a medical disorder 25—50 % have neurological or nonpsychiatric medical disorder  Can be resolved by suggestion  LA BELLE INDIFFERENCE CONDITION TEST Tunnel vision Visual fields Profound monocular blindness Swinging flashlight sign (Marcus Gunn) Binocular visual fields Severe bilateral blindness “Wiggle your fingers; I’m just testing coordination.” Sudden flash of bright light “Look at your hand.” “Touch your index fingers.” CONDITION TEST Aphonia Request a cough Intractable sneezing Observe CONDITION TEST Coma Examiner opens eyes Ocular cephalic maneuver Syncope Head-up tilt test CONDITION TEST Anesthesia Map dermatomes Hemianesthesia Check midline Astasia-abasia Walking, dancing Paralysis, paresis Hand drop onto face Hoover test Check of motor strength Insight-oriented supportive or behavior therapy Relationship with a caring and confident therapist most important feature of the therapy Reassurance  helping the patient verbalize distress  simple behavioral interventions   Presentation of the diagnosis avoid indirect and fragmentary discussion  naming: non epileptic seizure  Avoid mentioning ‘real’ or ‘unreal’  Validate the reality of events  Present the result of the tests   Cause of the disease We do not know the cause Symptoms have no clear physical cause Is not intentionally made Result from interaction between subconscious mind and body Role of stress Need of psychological interview Encourage the patient to acknowledge recent stresses  Give positive reinforcement  Take brief rest from stress before returning to usual activities  Advise against prolonged rest or withdrawal from activities   Symptoms usually resolve rapidly leaving no permanent damage  Acute cases ◦ Reassurance/appropriate rehabilitation  Resolution usually spontaneous  Chronic cases ◦ Aggressive therapy of comorbid psychiatric illness ◦ Pharmacotherapy  Anxiolytic or antidepressant medications ? ◦ Psychotherapy  comorbid psychiatric condition SSRI Beta-blockers Analgesics Benzodiazepines  psychological process by which one person may guide the thoughts, feelings or behaviour of another  waking suggestions  hypnotic suggestions        Family therapy Cognitive behavior therapy problem-solving techniques reframing of distorted cognitive beliefs Counseling Group therapy Hypnosis Psychodynamic approaches  Exploring intrrapsychic conflicts, and the symbolism of conversion symptoms ??? Good prognosis  Acute onset  Identifiable stressor  Short interval between onset and treatment  Paralysis  Aphonia  blindness   95%  20-25%  remit spontaneously Recurrence 25 to 50% neurological disorders or nonpsychiatric medical conditions affecting the nervous system THANK YOU Any Question?