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Nadin Abdel Razeq, PhD Objectives To gain awareness of the proper procedure of peripheral IV access in pediatrics To review types of IV fluids used in children To review basics of maintenance and deficit fluid and electrolyte requirements To gain awareness of the proper procedure of IVformula preparation and administration in pediatrics To review basics of IV medications administration in children! Proper Procedure of Peripheral IV Access in Children Let us watch a Video First … Then Let us Focus on Some Important Concepts All procedures at a treatment room Scalp Site and Arterial insertion To Get Better IV access you can… Number of IV access Attempts… Basic Concept :Osmotic Pressure Basic Concept :Osmolality of the blood Isotonicity of Blood = 275-295 mOsm/L Solutions having the same osmotic pressure as that of blood are said to be isotonic with blood. Solutions with a higher osmotic pressure than body fluids are called hypertonic Solutions with a lower osmotic pressure are called hypotonic. Types of IV fluids in children 0.9% NaCl (Normal Saline) 5% glucose in water Types of IV fluids in children 10% glucose in water 25% or 50% glucose in ------------------------- 15% or 20% glucose in water Give only via a central line as a 1-2ml/kg bolus for hypoglycaemia. Monitor blood glucose water Never as an infusion Only used in NICU and at low vol eg. 1-2mls/hr via central line Types of IV fluids in children 0.9% NaCl with 5% dextrose (Normal saline with glucose) Osmolarity: 560 Types of IV fluids in children 0.45% NaCl with 5% dextrose (1/2 Normal saline with glucose and no potassium 0.18% NaCl and 4% dextrose (4% and 1/5th normal saline) Types of IV fluids in children Ringer Lactate : 0-10 gram glucose/100cc Na 130 mEq/L NaHCO3 28 mEq/L as lactate K 4 mEq/L 273 mOsm/L Water for injection Maintenance Electrolyte Requirements Maintenance K Requirements: IV: 1-2 mEq/100ml of water/day OR 1-2mEq/kg/day Indications : Administration: Added only once the urine output is established. Strength: Calculate : • Side effect: ECG monitoring Frequent testing Maintenance Electrolyte Requirements Maintenance Ca Requirements: IV: 60 to 100 mg/kg/day Indications : Administration: Strength: Calculate : Side effect: IV formulas – Practice 100ml 0.9% NaCl + 20 ml 10% G/W + 5mEq KCL / 8 hrs Microdropper Calculation of Maintenance Fluid Requirements…the Holliday-Segar Method Class activity: A 30-kg child would require??? Kathleen Asas, MD.MPH Calculation of Maintenance Fluid Requirements… A 30-kg child would require (100 × 10) + (50 × 10) + (20 × 10) = 1,700 cc/day or (4 × 10) + (2 × 10) + (1 × 10) = 70 cc/h. Kathleen Asas, MD.MPH Oral Rehydration: Key Concepts Mild to moderate dehydration may be managed successfully with oral rehydration in the majority of cases. Oral rehydration solutions should contain glucose and sodium in a ratio not to exceed 2:1 Amount of rehydration solution to be given is based on the estimated percentage of dehydration by weight. Kathleen Asas, MD.MPH Oral Rehydration Patient vomiting – 5-10mL Q 5-10 minutes and increase as tolerated Mild Dehydration – Deficit replacement: 50 mL/kg over 4 hours Moderate Dehydration – Deficit replacement: 100 mL/kg over 4 hours Kathleen Asas, MD.MPH Phase I: Resuscitation using Isotonic Fluids (NS/LR) at 20ml/kg. Re-evaluation until urine output and dehydration signs improved Phase II: Calculate maintenance & deficit fluid Hypotonic Na <130 Determine if Isotonic, Hypotonic or Hypertonic Dehydration Hypertonic Na >150 Replace fluids over 48hrs** Isotonic 130< Na <150 Kathleen Asas, MD.MPH Resuscitation phase Goal: Restore circulation, re-perfuse brain, kidneys Mild-Moderate 20 mL/kg bolus given over 30 – 60 minutes Severe May repeat bolus as needed (ideally up to 60ml/kg) Fluids – something isotonic such as NS or lactated ringers (LR) Kathleen Asas, MD.MPH Replacement Phase Stabilization Phase (For Isotonic/Hypotonic Dehydration) Goal: Replace deficit of fluids and electrolytes Replacement Phase 1st 8 hrs Stabilization Phase Next 16 hrs MIVF and Maint Na 1/3 2/3 Deficit Fluid & Deficit Na 1/2 1/2 Kathleen Asas, MD.MPH IV Medications IV Medications - basic Concepts Correct : Patient Drug Dose Rout, IV or Oral ----- check IV site , Time, Time of Other Medications Documentation IV Medications - basic Concepts Administration : Micro-dropper for each Med Minimum dilution of drugs What to Do with the extra fluids Type of solution and computability Meds Never with blood product Duration of administration – Time of Other Medication