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Cronhns & Ulcerative Colitis What are these diseases? Crohns • Inflammation of segments of the GI tract in any part. Primarily the small intestine or colon. • Affects ages 15-30yrs • In the early stages tiny ulcers form on various parts of the intestinal wall, over time horizontal rows of these ulcers fuse with vertical rows causing mucus to take on a cobblestone appearance Ulcerative Colitis • Twice that of Crohns • Common enteric bacterium E.coli • Confined to the mucosa and submucosa of the colon, starts in the left then moves to the right. • Tiny abscesses form which grow and produce purulent drainage, capillaries become friable and blood causing diarrhea and pus. Pictures!! Clinical Manifestations Crohns • Onset is usually insidious with nonspecific complaints of diarrhea,fatigue abdominal pain weight loss and fever,dehydration,malnutri tion,anemia and increased peristalsis Ulcerative colitis • Diarrhea is a predominate sign • Usually 15-20 liquid stools a day containing blood, mucus and pus. • Abdominal cramps • Involuntary leakage of stools • May include toxic megacolon ( toxic dilation of large bowel) a lifethreating condition. What should we look for in Crohns?? Subjective • Weakness • Loss of appetite • Abdominal pain and cramps • Low grade fever • Stress Objective • Complaints of diarrhea • 3-4 semisolid stools daily containing mucus and blood What should we look for in Ulcerative Colitis? Subjective • Rectal bleeding • Abdominal distention • Lethargy • Unpredictable bowel movements Objective • Weight loss • Abdominal distention • Fever • Leukocytosis • Tachycardia Sigmoidoscopy and Colonoscopy • Tests Crohn’s • Colonoscopy with multiple biopsies of the colon • Granulomas in the biopsy specimen confirm Crohns Ulcerative Colitis • Barium studies of the intestine • Sigmoidoscopy • Colonoscopy with possible biopsy • Radiological examination of the abdomen How you would treat these diseases? Drug therapy Diet therapy (1) drugs that affect the inflammatory response. Corticosteriods (2) Antibacterial drugs (3) Drugs that affect the immune system (4) Antidiarrheal preparations. Lomotil -Remission pills such as Mesalmine • Surgical Interventions » » » » Iiestomy Proctocolectomy Colon resection Kock pouch Exclude milk products and highly spicy foods • High protein and high calorie diet • Exclude caffeine Interventions as a nurse • Nutrition, fluid balance, elimination, medications, psychological aspects and sexuality must be considered. • Thorough assessment of patients bowel elimination. • Oral diets of 2500mL per day for fluid loss • Monitor weight • Record I&O at least 1500mL per day • Support Support Support!! Prognosis • A patient with chronic ulcerative colitis is directly related to the number of years they have had the disease. • List of food that are known to cause constipation,diarrhea, blockage,odors, and flatus is helpful for the patient • Crohns disease is a chronic disorder and has a high rate of recurrence in pats under 25 yrs. • Prognosis depends on the extent of involvement,duration of illness, and success of medical intervention. No known therapy will maintain a patient with Crohn’s disease in remission. Review Questions 1) What is the 2) A high ____ and lifethreating _____ diet should be complication that can consumed with occur in UC? Crohn’s and Ulcerative Colitis. a) Abdominal distention b) Low grade temp c) Toxic megacolon d) All of the above