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Current Issues in Substance Abuse Joan E. Zweben, Ph.D. Executive Director, East Bay Community Recovery Project Clinical Professor of Psychiatry, UCSF Psychiatry Grand Rounds – Herrick Hospital January 7, 2013 The Substance Abuse Treatment System: Finding Good Care Comprehensive Assessment Current alcohol & other drug use AOD history Substance induced symptoms History and current treatment of other mental disorders SUDS treatment efforts Recovery support system & activities Are addiction meds appropriate? Substance-Induced Symptoms AOD USE CAN PRODUCE SYMPTOMS CHARACTERISTIC OF OTHER DISORDERS: Alcohol: impulse control problems (violence, suicide, unsafe sex, other high risk behavior); anxiety, depression, psychosis, dementia Stimulants: impulse control problems, mania, panic disorder, depression, anxiety, psychosis Opioids: mood disturbances, sexual dysfunction Psychotic Symptoms Hallucinations, paranoia: alcohol intoxication, withdrawal, overdose stimulant intoxication, overdose depressant intoxication, overdose hallucinogen intoxication, overdose phencyclidine intoxication, overdose Distinguishing Substance Abuse from Other Mental Disorders wait until withdrawal phenomena have subsided (usually by 4 weeks) physical exam, toxicology screens history from significant others longitudinal observations over time inquiry about quality of life during drug free periods Look for Evidence-Based Principles & Practices Evidence-based principles and practices guide system development Example: care that is appropriately comprehensive and continuous over time will produce better outcomes Evidence-based treatment interventions are important elements in the overall picture. They are not a substitute for overall adequate care. Translating EBTs into the Real World Distinguish between efficacy and effectiveness studies Huge gaps in the research literature (e.g., group interventions, therapist variables) Achieving fidelity is expensive, must be ongoing Infrastructure for ongoing evaluation is often inadequate ASAM Patient Placement Criteria PPC-2R DIMENSIONAL CRITERIA: 1. Acute intoxication and/or withdrawal 2. Biomedical conditions/complications 3. Emotional/behavioral/cognitive conditions and complications 4. Readiness to change 5. Continued problem potential 6. Living environment ASAM Levels of Care Level 0.5: early intervention Level I: outpatient services Level II: intensive OP/partial hospitalization Level III: residential/inpatient services Level IV: medically managed intensive IP Opioid maintenance therapy Marketing Impostors Distinguishing evidence from marketing Presenting multiple anecdotes with no comparison or control groups as “proof” Medications Options are good, but….. Beware the new drug “darling” Working Effectively with Returning Military Members Updated Roster of OEF, OIF, and OND Veterans Who Have Left Active Duty 1,318,510 OEF, OIF, and OND Veterans have left active duty and become eligible for VA health care since FY 2002 712,089 (~54%)* Former Active Duty troops 606,421 (~46%) Reserve and National Guard *Percentages reported are approximate due to rounding. Cumulative from 1st Quarter FY 2002 through 2nd Quarter FY 2011 John Straznikas, MD OEF/OIF Data 24% of OEF/OIF veterans responded positively to “used alcohol more than they meant to.” 21% OIF/ 18% OEF responded affirmatively that they “wanted or needed to cut down.” Hoge 2004 12% of OEF/OIF soldiers endorsed alcohol misuse. Milliken, Hoge 2007 (John Straznikas, MD) 2005 Survey of Health Related Behaviors from DOD Rates of Heavy Drinking – 5+ drinks/day: 26-55 yr olds – 9.7% Soldiers/9.5% Civilians 18-25 yr olds – Soldiers 25%/Civilians 17% (John Straznikas, MD) OEF/OIF/OND SUD Data Greater than a third of Army prosecutions are alcohol or drug related charges. 90% of military sexual crimes involve alcohol NY Times March 13, 2007 30% in rate of binge drinking from 2002 until 2005. Pentagon report 1/07 (John Straznikas, MD) PTSD and SUDs in OEF/OIF Veterans Rand Study – Dec 2008 Binge Alcohol: 50% (2x community) Tobacco Smoking: 50% (2x community) Opiate Abuse: 09% (3x community) Other Drugs: Marijuana, Sedatives, etc. Slide from: Kosten, Thomas, Treating PTSD and Addiction, 2009 Presentation Military Culture Take-home Points Make an effort to ask and learn about what the military was like for your patient. Have them teach you Know basic language Identify what is your patient’s view of their military/veteran status Examine your own biases Assess for weapons Basic Military History Which Branch did they serve in? Active Duty, National Guard or Reserves What was their job? Involved with combat? They are NOT the same! Peace-time or war-time service? Fire-fights, “being shot at”, mortars. Cooks and truck-drivers saw combat Unwanted sexual advances? Not all veterans view their military service the same Individual differences Cultural differences – VN vs. OEF/OIF Viewing the Military as a culture Cultural values Honor Respect Leave no brother behind Protect yourself - weapons Chain of command Follow orders Challenging ways veterans present to community-based programs Conformity – devalues the military and emphasizes the civilian life Dissonance – ambivalent about the two ‘cultures’ Immersion/Resistance – Idealization of the military and denigration of the civilian culture Using this Model to facilitate treatment engagement The ‘conforming’ veteran The ‘dissonant’ veteran Don’t challenge the devaluing Don’t actively join the devaluing Use Motivational Interviewing techniques to explore the ‘yes-but’ communications The ‘immersion/resistance’ veteran Don’t challenge the devaluing Focus on the present problem and solution Examine your own biases Your view of war Your view of the soldier Your view of perpetrators of violence Your view of perpetrators of atrocities Weapon assessment Assume they have a weapon Assume their weapon is an important part of their identity Ask specific questions about how they store the weapon and the bullets If lethality is active, negotiate storing bullets with a friend or getting a trigger lock. Special Issues with Traumatized Veterans SUD/PTSD Take Home Points for SUD/PTSD Complex and Confusing and Crisis-prone Expect an erratic therapeutic alliance Don’t blame them or yourself May take multiple treatment contacts Expect more crisis management, relapse and need for intensification of treatment structure Therapeutic Alliance is the primary treatment goal Reduces distress /discouragement with poor outcomes. More difficult to treat and worse outcomes with SUD/PTSD pts Fewer clinical improvements, more crises Uneasy alliance, negative counter-tranfx Poorer compliance with Aftercare tx Shorter time to relapse post treatment Drink more on drinking days Increased medical and interpersonal problems Increased homelessness Druley and Pashko 1988, Nace 1988, Brown and Wolfe 1994, Saladin et. al. 1995, Breslau et. al. 1997, Ouimette et. al. 1999, Najavits 1998 PREP: Prevention and Recovery for Early Psychosis Alameda County Collaboration Adolescent Substance Use Critical time for onset of SUDS Experimentation is prevalent; most do not develop SUDS Prevalence rates in higher risk samples is approx 24% or higher Social factors, esp peer influence, are strongest determinants of initiation of use. Psychological factors and effects of the substances more closely linked to abuse. (Millin & Walker, 2011) Adolescent Substance Abuse Adolescent brain more is susceptible to alcohol and other drugs Marijuana is the most prevalent, then alcohol. Polydrug use is the norm Tobacco: most smokers initiate during adolescence Prescription drug abuse is rising Prevention efforts target salient risk and protective factors Marijuana Impact on developing brain Distortions of self-concept due to disturbances of attention and concentration Conclude they are not intelligent, don’t like school; seek peer group with negative attitudes and behaviors Increased risk of psychotic illness Possible interference with medications (Zweben & Martin, 2009) PREP Collaborative: Alameda County EBCRP – Lead Agency - Administration of PREP Program - Administration of PREP Services FSASF • Community-based treatment; • Innovative funding options. • Training structure and capacity to document client outcomes MHA-AC - Outreach Marketing Stigma Reduction Community Education UCSF • Training in evidence-based practices • Diagnosis • Program evaluation and research. ACBHCS - Transition Age Youth System of Care - Issued initial RFP for TAY early psychosis funding Treatment as Usual vs. PREP • Case management (if severe enough) • 15-minute medication management, every 2-3 months • ?psychotherapy? – maybe “supportive” • Care management for everyone • Algorithm-based medication management, monthly visits+ • Cognitive Behavioral Therapy (CBT) • Little family involvement • Multi-Family Group • No specific vocational/ • Individualized vocational/ educational treatment educational support (IPS) Treatment as Usual vs. PREP • No treatment for cognitive symptoms • Referred out for substance use treatment • Computerized cognitive remediation • Harm reduction approach embedded throughout • Frequent hospitalization • Hospitalization minimized • Assumption of eventual housing/disability care • Focus on active recovery and return to full functioning Before and After PREP Hospitalizations Reduced by Half Symptom Change Real - World Functioning Medication Use at PREP: Outcomes • 23 clients whose medications were primarily managed by PREP: • 4 were not prescribed antipsychotic medication • 19 were prescribed antipsychotic medication • 5 switched from 2 or 3 antipsychotic agents to 1 • The average antipsychotic dose prescribed by PREP was 35% less than the World Health Organization’s defined daily dose* *http://www.whocc.no/atc_ddd_index/ Conclusions: PREP Works! Improves symptoms (depression), distress Reduces hospitalization and arrest rates While clients are taking the minimum medication dosages necessary Real-World Impact: Improves social functioning and functioning in school/work participation Referrals: 888-535- PREP (7737), Facilitating the Use of Mutual Help Groups Abstinence from Alcohol & Participation in AA Greater # meetings in 9-12 months, higher abstinence rates Weekly mtg attendance, higher abstinence rates at 2 years Sustained attendance, high abstinence rates (1-10+ yrs) (Kaskutas, L.A. 2009) 12 Steps: Parallels to Therapy understanding the negative consequences of AOD use understanding efforts to control use have not worked willingness to accept help taking inventory sharing with others 12 Steps, Cont. becoming willing to change identifying those harmed making amends ongoing awareness and effort to change behavior integrating changes into all aspects of behavior CBT and Other Concepts Embodied in 12-Step Programs community reinforcement social learning theory; use of social role models social support and recognition cognitive reframing social comparisons, use of social norms reference group theory catharsis cognitive control tools culture that embodies the values of recovery (John Wallace, Ph.D. 9/99) 12-Step Programs Resistances to Participation Stranger Anxiety Discomfort at being the outsider “I’m not an alcoholic/addict Fear of being engulfed “That religious stuff” Social isolation Facilitating the Use of 12-Step Programs Elicit picture of what meetings are like Explore charged issues Give permission to be ambivalent Stress “Take what you need and leave the rest” Surrender and empowerment Provide a place to talk about what is happening to them on a regular basis Preparing Psychiatric Patients for 12-Step Meetings medication is compatible with recovery, but meetings are best selected carefully some meetings are more tolerant than others of medication or eccentric behavior schizophrenics benefit from coaching on how to behave in meetings 12-step structure often beneficial; non-intrusive and stable References Kaskutas, Lee Ann. (2009). Alcoholics Anonymous Effectiveness: Faith Meets Science. Journal of Addictive Diseases, 28, 145-157. Acknowledgments: John Straznickas, MD (slides) Rachel Loewy, Ph.D. (slides) Resources www.ebcrp.org https://askprep.org/