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PULP CAP FEBRUARY 2013 COMPRESSED VERSION MTA THERAPIES • Root canal therapy – Perforation repair – Apicoectomy • • • • Indirect Pulp cap (Pink Dentin) Direct pulp cap (Direct Exposure) Pulpotomy (Coronal extirpation) Pulpectomy (Coronal and radicular extirpation) • Adult and pedodontic WHAT IS MTA • CALCIUM SILICATE – GYPSUM, PLASTER OF PARIS • DICALCIUM SILICATE – MAIN CONSTITUENT IN PORTLAND CEMENT • TRICALCIUM ALUMINATE (MINOR) • BIMUTH OXIDE ( 20%) FOR RADIOPACITY SUCCESSFUL PULP CAPS Healthy patient seal Recoverable pulp Inflammation management Flawless caries removal Histological repair Disinfection RETROSPECTIVE STUDIES 1. Bogan G et al JADA 2008:39 (3) 305-315 97% 2. Fuks AB, Pediatr Dent 1982,4: 240-244 81% success on permanent incisors 3. Barthel CR ,J Endod 2000; 26: 525-528 37% @ 5 years, 13% @10 years PULP CAP MATERIALS ? CR NEWS Jan 2010 • RMGI Vitrebond Plus or GC Fuji Lining LC – Indirect 40% – Indirect 68% • Calcium Hydroxide – 28% Direct, – 14% Indirect • Bonding agent – Direct 7% – Indirect 5% • • • • Laser 2% Direct Gluteraldehyde Indirect 3% MTA 3% Direct Polycarboxylate – no mention • Glass Ionomer – no mention • English sparrow poop CR News Jan 2010 vol 3 issue 1 1. CR respondents; success rates 1. 3 years: Direct 58%, Indirect 70% 2. 5 years: Direct 48%, Indirect 61% 100 90 80 70 60 50 40 30 20 10 0 DIRECT INDIRECT BOGAN FUKS BARTHEL 3 5 10 MTA • Bogan G et al JADA 2008:39 (3) 305-315 • Direct pulp capping with Mineral Trioxide aggregate – an Observational Study. • Over an observation period of nine years, the authors followed 49 of 53 teeth and found that 97.96% percent had favorable outcomes on the basis of radiographic appearance, subjective symptoms and cold testing. MTA: SUPPLIER • CLINICAL RESEARCH DENTAL • LONDON ONTARIO • 1800 265 3444 • “MTA ANGELUS WHITE” SUCCESSFUL PULP CAPS Healthy patient seal Recoverable pulp Inflammation management Flawless caries removal Histological repair Disinfection SUCCESSFUL PULP CAPS Healthy patient Recoverable pulp Inflammation management seal Histological repair Flawless caries removal Disinfection SUCCESSFUL PULP CAPS Healthy patient seal Recoverable pulp Inflammation management Flawless caries removal Histological repair Disinfection RADIOGRAPHIC CONTRAINDICATIONS • APICAL RADIOLUCENCY • APICAL DETERIORATION CONDENSING OSTEITIS • THREADLIKE PULP • PULP STONES • PROBABLE FUTURE PULP OCCLUSION E.G. CLASS V • RADIOGRAPHICLY EVIDENT CARIOUS INVASION OF PULP CHAMBER DIAGNOSTIC CONTRAINDICATIONS • • • • • • • • APICAL TENDERNESS SPONTANEOUS LONG STANDING NOCTURNAL THROBBING ENDURING SICKENING CONSTANT NEED OF MEDICATIONS OPERATIVE CONTRAINDICATIONS • • • • • EXUDATE – SEROUS PUS PROLONGED CLOTTING TIME > 5 MINS >3MM EXPOSURE GROSS CARIES INTRODUCTION INTO PULP CHAMBER • EXPLORER INTO THE PULP (OPERATOR ERROR) SUCCESSFUL PULP CAPS Healthy patient seal Recoverable pulp Inflammation management Flawless caries removal Histological repair Disinfection FORMULA FOR CARIES DETECTOR • ACID RED 52 2% IN PROPYLENE GLYCOL • COMPOUNDING PHARMACY • $30 FOR 200 CC.= 5 YEARS’ SUPPLY ref CARIES DETECTOR - NO EFFECT ON BOND STRENGTH • El-Housseiny and Jamjoum, J Clin Pediat Dent 2000 • Kazemi et al, Oper Dent 2002 AFFECTED DENTIN INFECTED DENTIN SETTING THE STAGE FOR PULPAL HEALING • EXPOSURE ZONE: • LOW/NIL BACTERIAL COUNT • CONTIGUOUS ZONE • BIOCOMPATIBLE AND CALCIGENIC AGENT • VISIBLE DELINEATION FOR FUTURE INTERVENTIONS • PERIPHERAL ZONE • PERFECT SEAL MICROLEAKAGE) (ZERO (ZERO ZERO • TUBULES % AREA 90% 10% • NUMBER/ MM2 20 K 60K • DIAMETER • PRESSURE NIL 1u 3u POSITIVE!!! • SE BONDS LESS EFFECTIVE THAN ETCH AND RINSE IN DEEP DENTIN SUCCESSFUL PULP CAPS Healthy patient seal Recoverable pulp Inflammation management Flawless caries removal Histological repair Disinfection LEAVING CARIES? JOE — Volume 36, Number 9, September 2010 Long-term Survival of Indirect Pulp Treatment Performed in Primary and Permanent Teeth with Clinically Diagnosed Deep Carious Lesions Rene´ Gruythuysen, DDS, PhD, Guus van Strijp, DDS, PhD, and Min-Kai Wu, MSD, PhDE CR JAN 2010 2 APPLICATIONS ONE MINUTE EACH ref • CR News Jan 2010 vol 3 issue 1 • http://www.cliniciansreport.org/products/den tal-reports/january-2010-volume-3-issue1.php • Subscription required POTENTIAL DISINFECTANTS • ENDODONTIC • PULPAL • • • • • HYPOCHLORITE KANCA • CHLORHEXEDINE-MANY SILVER NITRATE IODINE FORMOCRESOL CA(OH)2 ref CHLORHEXEDINE NO EFFECT ON BOND STRENGTH • Santos et al, JOE, 2006 • Perdiao et , Am J Dent 1994 WHAT ABOUT SURFACE DISINFECTANTS? • • • • HYPOCHLORITE 70% ALCOHOL WITH PHENOLS 70% ALCOHOL WITH CHX ACCELERATED PEROXIDE ref NaOCl • IS A STRONG OXIDIZING AGENT • REDUCES BOND STRENGTH OF DENTIN BONDING AGENTS • Ari et al, JOE, 2003 • Erdemir et al, JOE, 2004 • Santos eta l JOE, 2006 • Lai et al, J Deny Res 2001 REVERSING NaOCl EFFECTS ON DBAS A reducing agent, such as ascorbic acid, or sodium ascorbate, reverses the effect of NaOCl on bonding strength Morris et al, JOE, 2001 Lai et al, J Dent Res, 2001 Yiu et al, J Dent Res, 2002 Weston et al JOE, 2007: 10% Na ascorbate for 1 min restored the original bond strength EDTA reverses effect of NaOCl • Doyle t al, JOE, 2006 • A final rinse with EDTA reversed the effects of NaOCl on bonding H2O2 reduces bond strength of DBAs • Erdemir et al JOE, 2004 • Nikaido et al, Am J Dent 1999 DEEP CARIES DISINFECTION • Optim 33TB Sci Can • One minute kill =10 Log -6 • TB effective • CR tested April 2007 • Excellent surface cleaner • Tissue compatible DISINFECTION PRIOR TO EXPOSURE • • • • GET CLOSE WITH DETECTOR OPTIM 33TB ONE MINUTE NO DETECTOR FINAL EXCAVATION – SLOW RPMS – SPOON • ACID ETCH 10 SECONDS/RINSE – REMOVE SMEAR LAYER • OPTIM 33 ONE MINUTE – PENETRATE TUBULES OPTIONS FOR REMOVING SMEAR LAYER & PENETRATING TUBULES • • EDTA 14% SmearClear (SybronEndo) – 17%EDTA ,surfactant • QMix (Tulsa/Dentsply) – • • CHX digluconate, <15% EDTA, surfactant Phosphoric Acid etch Citric acid CAPPING THE EXPOSURE: CAP, SEAL CAP WITH RESIN, RESTORE • FINAL EXCAVATION; EXPOSE if still carious • MTA DIRECT CAP • IMMEDIATE OVERSEAL WITH UNMODIFIED GLASS IONOMER (LUTING CEMENT) • ALLOW GI TO SET (APPROX 4 MINS) • EDTA TO RESTORE BONDABILITY • PA ETCH/RINSE/DRY PRIME/DRY+ BOND/THIN/EVAPORATE • SEAL CAP PERIMETER FLOWABLE/CURE • SEAL REMAINING DENTIN AND GINGIVAL MARGIN WITH FLOWABLE AND CURE • RESTORE WITH FINAL RESIN FOLLOWING LOW CONTRACTION STRESS PRINCIPLES , IE, INCREMENTING • FINISH AND ARTICULATE METICULOUSLY MTA MECHANISM • Silviera CMM et al. Repair of Furcal Perforation with Mineral Trioxide Aggregate: Long-Term Follow-Up of 2 Cases JCDA October 2008 Vol 74 #8 729-732 • http://www.cda-adc.ca/jcda/vol-74/issue8/729.html MTA MECHANISM • Saidon J et al. OSOMOPOR Endod 2003:95:483-489 “Cell and tissue reactions to mineral trioxide aggregate (MTA) and Portland cement.” • MTA and Portland cement show comparative biocompatibility when evaluated in vitro and in vivo. The Portland cement was sterilized by ethylene oxide. MTA MENTE ET AL • Johannes Mente, DMD, et al J. Endo May 2010 806-814 • Mineral Trioxide Aggregate or Calcium Hydroxide Direct Pulp Capping: An Analysis of the Clinical Treatment Outcome • 5 years, 167 teeth • 80% success MTA, 60% Ca(OH)2 • i.e. Twice as much failure with Ca(OH)2 Mente, DMD, et al J. Endo May 2010 • • • • • • Dentin bridge formation with MTA appears more homogenous (fewer tunnel defects) and more localized than that formed with Ca(OH)2 (20–24). caries was excavated from the cavity walls. Near to the pulp, except for one carious spot, the removal of which resulted in exposure of the pulp, the cavities were routinely disinfected with 0.12% chlorhexidine solution (Glaxo Smith Kline GmbH, Buhl, Germany). Resolution of bleeding from the exposed pulp in less than 5minutes was considered to be indicative of reversible inflammation The MTA pulp cap was overlaid with a thin protective layer of resin modified glass ionomer cement (Vitrebond; 3M Espe) The reduction in clinical success if a direct pulp capping is not followed immediately with permanent restoration has been shown in other clinical studies (11, 12) The longer the follow-up period, the more evident the trend decline in the success rate of the teeth in the Ca(OH)2 group compared with the MTA group. SUCCESSFUL PULP CAPS Healthy patient seal Recoverable pulp Inflammation management Flawless caries removal Histological repair Disinfection RESIN BIOCOMPATIBILITY??? • Volk,J, Engelmann,J.,Leyhausen,G.,Geurtsen,W. • Dental Materials 2006 22:499-505 • Effects of three resin monomers on the cellular glutathione concentration of cultured human fibroblasts See Website: Home>MODXYZ> Biocompatibility ref DYRACT AND DYRACT-CEM AND VITREBOND • J Dent Res. 1998 Dec;77(12):2012-9. Residual monomer/additive release and variability in cytotoxicity of lightcuring glass-ionomer cements and compomers. Geurtsen W, Spahl W, Leyhausen G. Severe cytotoxic effects were observed in response to both of these materials • Mutat Res. 1996 Jul 5;368(3-4):181-94. • Genotoxicity of dental materials. Heil J, Reifferscheid G, Waldmann P, Leyhausen G, Geurtsen W. Genotoxic effects were found for Vitrebond and AH 26 (since upgraded to AH26 Plus) GLASS IONOMER BIOCOMPATIBILITY • Biomaterials. 1998 Mar;19(6):559-64. Biocompatibility of various light-curing and one conventional glass-ionomer cement. Leyhausen G, Abtahi M, Karbakhsch M, Sapotnick A, Geurtsen W. Two GIs was found to be very biocompatible, while Vitrebond was found to be cytotoxic. NEW - BIODENTINE • • • • SEPTODONT $17 PER APPLICATION REQUIRES TRITURATOR IS MEANT TO BE A COMPLETE TEMPORARY FILLING • STICKY HANDLING • INDEPENDENT REVIEW YET TO BE SEEN Theracal- Bisco PEDODONTIC PULPOTOMY SUCCESSFUL PULP CAPS Healthy patient Inflammation management Recoverable pulp Seal Flawless caries removal Histological repair Disinfection SEALING THE PULP CAP IMMEDIATE RESTORATION improves prognosis 30% (Mente et al) PROTECT THE CAP from shrinkage FINAL RESTORATION with low sensitivity technique CAREFUL OCCLUSION CAREFUL AND ACCURATE OCCLUSION SUCCESSFUL PULP CAPS Healthy patient Recoverable pulp Histological repair Inflammation management Flawless caries removal seal Disinfection INFLAMMATION MANAGEMNT • MEDICATION • COMMUNICATION – Disciplined use of 1. Cautious prognosis Ibuprofen 400 mg for 24 2. “Call me I want to hours q4h 6 tabs know” – Instruct to use regardless 3. Next day follow-up call if painful or not 11 am • Alternative for NSAIDintolerant patients: 4. Not that night! dexamethasone 5. Inform that success may be temporary THE END