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Pediatric Respiratory Emergencies Amy Gutman MD EMS Medical Director Tobey Hospital [email protected] Conflicts of Interest • Sadly, I have no corporate sponsorships or private funding to declare • Employed by Tobey Emergency Associates, a private EM group staffing Tobey Hospital Emergency Department (Southcoast Hospitals Group) • Medical Director for a bevy of awesome Fire & EMS Departments & training programs for which I am paid an enormous amount of money (ahem) Overview • Review critical aspects of prehospital care of pediatric respiratory emergencies – Epidemiology – Anatomy – Specific disease processes • Emphasizing children have unique pathophysiology & respond differently to respiratory illness than adults • Most importantly: – How to recognize “sick” – Management strategies for respiratory distress – Timely recognition of respiratory distress & appropriate intervention key to preventing progression to cardiac arrest Sick or Not Sick? Pediatric Epidemiology • 26% US population, 10% EMS calls • Respiratory distress #1 cause of admissions & death during 1st year except for congenital abnormalities • Most pediatric cardiac arrests begin as respiratory failure • Minimal training, few ill pediatric patients makes it difficult to obtain & maintain skills • Multiple sized pts, equipment sizes & drug dosages confusing in stressful situations “External” Airway Anatomy • Large head, large tongue, small mandible • Narrowest at subglottic / cricoid area • Relatively straight cervical spine • Less rigid thoracic cage with poor accessory muscle development • Horizontal ribs, diaphragm breathers • Increased metabolic rate, increased O2 consumption, limited O2 reserves Smaller “Internal” Airway • Epiglottis floppy, U shaped & anterior • Larynx anterior • Short floppy trachea • Small soft airways in obligate nasal breathers – Nose = 50% airway resistance – Large tonsils, adenoids rapidly swell • Pliable / floppy trachea collapses easily (Poiseuille’s Law) – Adult: 1 mm edema = 81% size – Pedi: 1 mm edema = 44% size Patient Needs • Fear of separation, being hurt & the unknown • Allow family to be with patient as long as it does not distract you • Never lie! • Always explain your plan to the child • Position at eye level, remain calm, speak slowly Assessment • Pre-arrival preparation & scene size-up • General assessment (Pediatric Assessment Triangle) Work of Breathing – “Sick” vs “Not Sick” vs “Could Rapidly Become Sick” – Clinical indicators reflect CV, respiratory & neurological status • ABCDE & transport decision • Ongoing assessment including more thorough history & exam CUPS: Critical, Unstable, Potentially Unstable, Stable HPI & Exam • HPI – – – – • How fast deteriorating? Fever? Noisy breathing? What has been done so far? PMH – Prematurity, hospitalizations, Illnesses, intubations, immunizations? – Allergies? – Medications? • Exam – – – – – – Sick or Not Sick? Rate? Noisy? Position? Color? Symmetric? “Normal” Vitals AGE AGE HR HR 0-3 mo 140 60-90 20-60 3 mo–2 yrs 140 90–105 55-65 2 yrs–5 yrs 90 95–105 55-65 6yrs–10 yrs 80 100–115 60-72 >10 yrs 75 115–125 65-85 SBP SB DBP Appearance • Alertness • Distractibility • Consolability • Eye contact • Speech/cry • Spontaneous motor activity • Color Abnormal Breathing Sounds • Stridor – High pitched sound heard on inspiration – Indicates upper airway obstruction • Grunting – Short, low pitched sound heard in expiration – Auto-PEEP to keep small airways open as progresses towards respiratory failure • Wheezing – High-pitched whistling sound heard expiration > inspiration – Indicates lower airway obstruction • Crackles – Crackling sounds heard on inspiration – Associated with cardio-vascular disease, lung disease, infection Respiratory Distress vs Failure • Distress – Maintain oxygenation only by increasing work of breathing • Failure – Cannot compensate for inadequate oxygenation despite extra respiratory effort & rate – Circulatory & respiratory system collapse Distress Tachypnea Nasal Flaring / Pursed Lips Stridor / Wheezing AMS / Agitation Agitation Tachycardia Delayed Capillary Refill Pale Failure RR > 60 Retractions Grunting Mottling Head Bobbing Severe Air Hunger Bradycardia Hypotension Arrest Bradypnea Inefficient respirations Cyanosis / Grey No air movement Management Strategies • Treat the symptoms, not the disease • Every child with respiratory distress needs oxygenation as uncorrected respiratory distress deteriorates to bradycardia & cardiac arrest • Priority is to support breathing effort – Remember the basics! • If pulse remains low or breathing inadequate, re-evaluate airway, ventilations, O2 & tubing 15 Airway Management • Use pediatric assessment triangle to determine oxygenation status & O2 delivery device • Neutral “sniffing” head position – – Towel under shoulders; do not flex head which collapses trachea Head-tilt chin lift or jaw-thrust • <5 seconds to look, listen & feel • Suction airway • Appropriate ventilation volume & rate (4-6 mg/kg) – – Maintain optimal cardiac output, venous return, cerebral blood flow & coronary perfusion Limits regurgitation & aspiration 7 Ps…Not Just For RSI 1. Preparation 2. Pre-oxygenation 3. Premedication 4. Paralyze 5. Pass tube 6. Placement proof 7. Post-intubation care Endotracheal Intubation • EMS adult success rate: 85%–95% EMS pediatric success rate: 50%–80% • 2005 AHA: – Cuffed ETT effective & safe for all ages, but un-cuffed ETT recommended in neonates • Rapidly deoxygenate & decompensate – Prepare to start compressions – “Hail Mary” plan ETT & Resuscitation • Smartphone apps: – RapiTube, Difficult Airway, PediStat , PediSafe • Traditional Calculations: – Un-cuffed = (Age / 4) + 4 – Cuffed = (Age / 4) + 3 – General = Age + 16/4 • [6yo + 16]/4 = 22; 22/4 = 5.5 ETT • Ready ETT 0.5 mm smaller & larger • Use blade you like: – In very young Miller directly lifts floppy epiglottis – In older children Macintosh slides into vallecula & indirectly lifts epiglottis Alternative Airways • Supraglottic, LMA, videoscope • Supraglottics & LMAs placed blindly with insertion times approximately 5 secs even during compressions • Confirm BL lung sounds, ETCO2, tube fog, rising O2 sat & HR Secure The Tube! Secure The Baby! Upper vs Lower Airway Diseases • Upper Airway – – – – – • Foreign Body Obstruction Retropharyngeal Abscess Bacterial Tracheitis Epiglottitis Croup Lower Airway – RSV / Bronchiolitis – Asthma – Bronchitis / Pneumonia Apparent Life Threatening Events (ALTE) • Lifeless, pulseless or unresponsive infant recovering spontaneously & “looks normal” – 1-2% infants – Most common at 2-3 mo, uncommon >2 yrs • All require transport & admission • DDX: – – – – – Arrythmias Congenital heart disease Abuse / Trauma GERD Infectious / Metabolic / Neurological disorders – Respiratory compromise – Munchausen’s Foreign Body Aspiration / Obstruction (FBAO) • >90% respiratory deaths in <5 yo; 65% infant deaths from respiratory causes • Suspect in sudden respiratory distress, choking / coughing, stridor or wheezing • DDX: seizure, syncope, arrhythmia or overdose • Large objects lodge in upper airway & trachea – 20% FBAO – Acute dyspnea, drooling, stridor & cyanosis • Small objects lodge in bronchus / terminal airway Choking / FBAO • Able to talk or minimal distress, rapidly transport in position of comfort • Responsive but significant distress: – Child: abdominal thrusts or Heimlich – Infant: chest thrusts, back blows • Unresponsive, open airway & only remove object if visible / accessible – Begin CPR with airway check – Look for FB prior to starting each ventilation; if visible attempt removal with Magill’s – Airway management via PPV or advanced airway attempt • Rapid transport & notify receiving hospital • Medical Control for needle cricothyroidotomy if unable to clear obstruction, unable to intubate or ventilate Even If obstruction clears prior to your arrival, still transport Retropharyngeal Abscess • URI complication • Lymph nodes between posterior pharynx & pre-vertebral fascia – Soft palate bulging obstructs nose – Posterior pharynx bulging obstructs trachea • Abrupt fever, severe distress, painful swallowing • Head hyperextension • Noisy respirations, drooling Epiglottitis (H. Influenza) • 4-6 yo most common • 10 X decrease since H. flu vaccinations – 10% are vaccinated, but exposed to virulent strain • High fever, sore throat, stridor, drooling, tripoding & severe respiratory distress • Supraglottic edema completely obstructs airway – DO NOT attempt to visualize (“Sniff Test”) • Manage according to severity of condition but rapidly transport in upright position with humidified O2 Respiratory Distress + Sore Throat + Drooling Croup (Viral Parainfluenza) • Nightly recurring fever, hoarseness, “barking seal” cough from laryngeal & tracheal edema • 6 mo to 4 yr – Males > Females – Fall, early winter • Management: – – – – – Reassurance Humidified, cool air Steroids Racemic epinephrine Rare advanced airway management; consider alternative diagnoses Bacterial Tracheitis • Post URI • Purulent sputum, high fever, pseudomembrane • Toxic appearance + stridor • Croup-like symptoms responding poorly to croup management Bronchiolitis (RSV) • Viral bronchiolar edema from air trapping • >80% < 1 yo • Epidemics January - May • Recent URI with gradual onset of SOB • Expiratory wheezing, tachypnea, cyanosis • Management – Humidified oxygen – Bronchodilators – Advanced airway as needed Asthma • Lower airway hypersensitivity causing bronchospasm, edema & mucus production – Varying degrees of respiratory distress – All that wheezes is not asthma – Non-wheezers often in severe respiratory distress • Important History – – – – • Prior ICU admission / intubations >3 ED visits or >2 admissions in past yr >1 MDI used in past mo or every 4 hrs Symptom progression despite aggressive treatment Management is aggressive airway, pharmacology & fluid resuscitation – – – – Position of comfort, humidified O2 Beta-2 agents (Albuterol) Anticholinergics (Atropine, Ipatropium) Subcutaneous beta agents (Epinephrine 1:1000, 0.1 to 0.3 mg SQ) Bronchitis / Pneumonia • Viral or bacterial – Neonates: GBS, enterics – 3 mo-3yr: Streptococcus pneumonia – 4mo- Preschool: RSV / viral • Fever, cyanosis + tachypnea, cough, nasal flaring, retractions, rales, decreased breath sounds • Aggressive airway management Acute Respiratory Distress (ARDS) • Severe lung inflammation rapidly resulting in hypoxia & respiratory failure • Frequency: 2-12/100,000 • Mortality: 15% • Management: – Aggressive airway control – PEEP – Fluid & cardiovascular resuscitation Anaphylaxis • Acute & life-threatening • Release of inflammatory mediators after a trigger – MEWS: Milk, eggs, wheat, soy – Peanuts & shellfish most potent – Others: preservatives, medications, insect venom, blood products, environmental, animal, exercise • Symptoms progress over minutes to days resulting in respiratory failure, shock, multiorgan system failure & DIC – 5-20% experience recurrence of anaphylaxis >12 hrs – Symptoms can last 3 days despite treatment Anaphylaxis Management • Airway – Oxygen + adjuncts including CPAP – Make early aggressive choices including advanced airway • Medications: – – – – • Diphenhydramine Histamine blocker (pepcid, zantac) Nebulized or MDI albuterol (2.5-5 mg/dose) Epinephrine 1:1000 IM Anaphylactic Shock: – – – – Beware of “compensated shock” Trandelenburg position 20 mL/kg crystalloid bolus; repeat to 60-80 mL/kg as necessary Vasopressors: • Epinephrine (0.1-1 mcg/kg/min IV) • Dopamine (2-20 mcg/kg/min IV) • Norepinephrine (0.1-2 mcg/kg/min IV) Pediatric Bronchospasm / Respiratory Distress • Activate ALS intercept; rapidly transport without ALS if necessary • Mild Distress – If not taken max dose of prescribed MDI, encourage or assist patient to self-administer – Med Control for 2nd MDI dose if max not administered. MDI contraindicated if max dose administered, pt cannot physically use device, device not prescribed for patient • ALS: – IV, O2, Monitor – If not improving with O2, consider albuterol / atrovent nebulizer or MDI – Medical Control: • Epinephrine 0.15-0.3 mg IM autoinjector • Magnesium Sulfate 25 mg/kg IV over 5 min – Treat for shock as needed • Notify receiving hospital Special Patients • Tracheostomy tubes, apnea monitors, ventilators are common home-care devices • Most common are trach-related emergencies – – – – – • If ineffective ventilation/oxygenation: – – – – • Obstruction Tube dislodgement Stoma bleeding Tube reinsertion “false track” Infection Wipe stoma, suction tube Remove tube if necessary Once airway open, begin PPV Attempt intubation if cannot oxygenate Med Control may order tube re-insertion References • • • • • • • • • • • • • • • • Emergency Care & Transportation of the Sick and Injured, 9th ED Massachusetts OEMS (www.dph.org) Alameda County EMS www.emsonline.com Premier Health Care Services Continuing Education and Training Pediatric Advanced Life Support (PALS) Pediatric Education for the Prehospital Provider (PEPP) Pediatric Emergency Assessment, Recognition & Stabilization (PEARS) [email protected] NAEMT Emergency pediatric Care www.emsc.org E Humphreys PA-C, EMT-I “Pediatric Respiratory Emergencies” (2009) J Reynolds MD “Pediatric Respiratory Emergencies” (2012) S Villanueva MD, FACEP “Pediatric Respiratory Emergencies”. 2011. “Management of acute lung injury & ARDS in children”. Critical Care. 2009. Summary • Pre-arrival preparation important • Standardized approach to assessment & management • Knowledge of normal child development and age-specific physiology important • “Sick/not sick” determination is paramount in treatment & transport decisions Find me: Nights at Tobey ED Email me: [email protected] / Website: www.TEAEMS.com Text me: 513-255-1353